KEGG   ORTHOLOGY: K11415
Entry
K11415                      KO                                     

Name
SIRT5, SIR2L5
Definition
NAD+-dependent protein deacetylase sirtuin 5 [EC:2.3.1.286]
Pathway
ko00760  Nicotinate and nicotinamide metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K11415  SIRT5, SIR2L5; NAD+-dependent protein deacetylase sirtuin 5
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K11415  SIRT5, SIR2L5; NAD+-dependent protein deacetylase sirtuin 5
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.286  protein acetyllysine N-acetyltransferase
     K11415  SIRT5, SIR2L5; NAD+-dependent protein deacetylase sirtuin 5
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Histone modification proteins
   HDACs (histone deacetylases)
    SIRTs (sirtuins, class III HDACs)
     K11415  SIRT5, SIR2L5; NAD+-dependent protein deacetylase sirtuin 5
Other DBs
RN: R10633 R10634
Genes
HSA: 23408(SIRT5)
PTR: 747069(SIRT5)
PPS: 100985261(SIRT5)
GGO: 101146991(SIRT5)
PON: 100189679(SIRT5)
NLE: 100582821(SIRT5)
MCC: 700855(SIRT5)
MCF: 102138500(SIRT5)
CSAB: 103222143(SIRT5)
RRO: 104672592(SIRT5)
RBB: 108541593(SIRT5)
CJC: 100409461(SIRT5)
SBQ: 101051064(SIRT5)
MMU: 68346(Sirt5)
MCAL: 110308397(Sirt5)
MPAH: 110333965(Sirt5)
RNO: 306840(Sirt5)
MUN: 110544304(Sirt5)
CGE: 100767069(Sirt5)
NGI: 103732881(Sirt5)
HGL: 101718891(Sirt5)
CCAN: 109685517 109685520(Sirt5)
OCU: 100339154(SIRT5)
TUP: 102471182(SIRT5)
CFA: 478726(SIRT5)
VVP: 112920537(SIRT5) 112928185
AML: 100469747(SIRT5)
UMR: 103664900(SIRT5)
UAH: 113264471(SIRT5)
ORO: 101381670(SIRT5)
ELK: 111156676
FCA: 101089862(SIRT5)
PTG: 102949922(SIRT5)
PPAD: 109249621(SIRT5)
AJU: 106974181(SIRT5)
BTA: 507347(SIRT5)
BOM: 102280522(SIRT5)
BIU: 109577246(SIRT5)
BBUB: 102411275(SIRT5)
CHX: 100860989(SIRT5)
OAS: 101104099(SIRT5)
SSC: 100125966(SIRT5)
CFR: 102509749(SIRT5)
CDK: 105089089(SIRT5)
BACU: 103018550(SIRT5)
LVE: 103072883(SIRT5)
OOR: 101276018(SIRT5)
DLE: 111181373(SIRT5)
ECB: 100051757(SIRT5)
EPZ: 103551671(SIRT5)
EAI: 106836560(SIRT5)
MYB: 102260946(SIRT5)
MYD: 102753056(SIRT5)
MNA: 107540371(SIRT5)
HAI: 109393189(SIRT5)
DRO: 112309324(SIRT5)
PALE: 102893890(SIRT5)
RAY: 107499254(SIRT5)
MJV: 108409410(SIRT5)
LAV: 100671587(SIRT5)
TMU: 101350662
MDO: 100026454(SIRT5)
SHR: 100919915(SIRT5)
PCW: 110208679(SIRT5)
OAA: 100084511(SIRT5)
GGA: 420834(SIRT5)
MGP: 100548081(SIRT5)
CJO: 107309713(SIRT5)
NMEL: 110394208(SIRT5)
APLA: 101793845(SIRT5)
ACYG: 106041701(SIRT5)
TGU: 100220330
LSR: 110483427(SIRT5)
SCAN: 103819409(SIRT5)
GFR: 102033998(SIRT5)
FAB: 101820797(SIRT5)
PHI: 102100972(SIRT5)
PMAJ: 107199842(SIRT5)
CCAE: 111923925
CCW: 104691427
ETL: 114059470(SIRT5)
FPG: 101915619(SIRT5)
FCH: 102060061(SIRT5)
CLV: 102093099
EGZ: 104125486(SIRT5)
NNI: 104021805(SIRT5)
ACUN: 113477336(SIRT5)
PADL: 103919047(SIRT5)
AAM: 106483417(SIRT5)
ASN: 102370553(SIRT5)
AMJ: 102570727(SIRT5)
PSS: 102463555(SIRT5)
CMY: 102931061(SIRT5)
CPIC: 101936381(SIRT5)
ACS: 100562942(sirt5)
PVT: 110081688(SIRT5)
PBI: 103051631(SIRT5)
PMUR: 107286340(SIRT5) 107287021
TSR: 106547979(SIRT5)
PMUA: 114600869(SIRT5)
GJA: 107106244(SIRT5)
XLA: 447308(sirt5.S) 496346(sirt5.L)
XTR: 100170199(sirt5)
NPR: 108792801(SIRT5)
DRE: 100536119 436878(sirt5)
IPU: 100528250(sirt5) 108268057
PHYP: 113545351(sirt5) 113547299
AMEX: 103031700(sirt5) 111194338
EEE: 113582991 113588649(sirt5)
TRU: 101074434(sirt5)
NCC: 104962438(sirt5)
MZE: 101466609(sirt5) 101476082
OLA: 101162440(sirt5) 101163111
XMA: 102226825(sirt5) 102227585
XCO: 114146803 114150751(sirt5)
PRET: 103463402(sirt5) 103479554
CVG: 107083000(sirt5) 107092410
NFU: 107383913 107393051(sirt5)
KMR: 108239590 108248348(sirt5)
ALIM: 106532264(sirt5) 106533933
AOCE: 111568703 111569881(sirt5)
CSEM: 103396282 103399853(sirt5)
POV: 109639223(sirt5) 109647853
LCF: 108879583(sirt5) 108883417
SDU: 111227531(sirt5) 111231072
SLAL: 111670468 111671795(sirt5)
HCQ: 109521238 109524717(sirt5)
BPEC: 110158058 110172275(sirt5)
MALB: 109957715 109961281(sirt5)
SASA: 106560408 106569266 106584069(sirt5) 106599723(SIRT5)
OTW: 112250233(sirt5)
PKI: 111845831 111850102(sirt5)
LCM: 102346114(SIRT5)
CMK: 103171981(sirt5)
RTP: 109917225
BFO: 118417268
CIN: 100177952
SPU: 574945
APLC: 110983071
SKO: 100374956
AME: 552701
BIM: 100746435
BTER: 100644308
CCAL: 108629785
OBB: 114874218
SOC: 105204171
MPHA: 105834705
AEC: 105152998
ACEP: 105627479
PBAR: 105429657
VEM: 105558397
HST: 105189544
DQU: 106743308
CFO: 105256202
LHU: 105671359
PGC: 109858612
OBO: 105275121
NVI: 100122998
MDL: 103568755
TCA: 661574
ATD: 109608796
BMOR: 101741654
BMAN: 114240799
PRAP: 110996970
TNL: 113500582
PXY: 105382870
BTAB: 109032844
CLEC: 106665797
ZNE: 110827176
TUT: 107362555
DPTE: 113797396
PTEP: 107439463
PCAN: 112577137
CRG: 105331278
MYI: 110440277
OBI: 106882983
SHX: MS3_03622
EGL: EGR_00605
NVE: 5519523
EPA: 110236562
ADF: 107343868
AMIL: 114957780
PDAM: 113679217
SPIS: 111330677
DGT: 114516668
AQU: 100637022
PPP: 112294038
TDL: TDEL_0E01780(TDEL0E01780)
PIC: PICST_35457(SIR1)
CAL: CAALFM_C102740CA(CaO19.2963)
SLB: AWJ20_2533(UGO1)
NTE: NEUTE1DRAFT88258(NEUTE1DRAFT_88258)
MGR: MGG_15048
NHE: NECHADRAFT_94915(SRT2101)
MAW: MAC_02742
CMT: CCM_04008
ANI: AN1782.2
ANG: ANI_1_932094(An11g06980)
ABE: ARB_05290
TVE: TRV_02327
PTE: PTT_13395
TASA: A1Q1_04732
ABP: AGABI1DRAFT79637(AGABI1DRAFT_79637)
ABV: AGABI2DRAFT187357(AGABI2DRAFT_187357)
NGD: NGA_0390700(NPDA)
CCRO: CMC5_022870(cobB)
 » show all
Reference
  Authors
Saunders LR, Verdin E
  Title
Sirtuins: critical regulators at the crossroads between cancer and aging.
  Journal
Oncogene 26:5489-504 (2007)
DOI:10.1038/sj.onc.1210616
  Sequence
[hsa:23408] [mmu:68346]

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