KEGG   ORTHOLOGY: K12076Help
Entry
K12076                      KO                                     

Name
DLG1
Definition
disks large protein 1
Pathway
ko04390  Hippo signaling pathway
ko04391  Hippo signaling pathway - fly
ko04530  Tight junction
ko04660  T cell receptor signaling pathway
ko05165  Human papillomavirus infection
ko05166  HTLV-I infection
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04390 Hippo signaling pathway
    K12076  DLG1; disks large protein 1
   04391 Hippo signaling pathway -fly
    K12076  DLG1; disks large protein 1
 Cellular Processes
  Cellular community - eukaryotes
   04530 Tight junction
    K12076  DLG1; disks large protein 1
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    K12076  DLG1; disks large protein 1
 Human Diseases
  Cancers
   05203 Viral carcinogenesis
    K12076  DLG1; disks large protein 1
  Infectious diseases
   05166 HTLV-I infection
    K12076  DLG1; disks large protein 1
   05165 Human papillomavirus infection
    K12076  DLG1; disks large protein 1
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Centrosome formation and ciliogenesis proteins
   Other centriole associated proteins
    K12076  DLG1; disks large protein 1
BRITE hierarchy
Genes
HSA: 1739(DLG1)
PTR: 460968(DLG1)
PPS: 100987596(DLG1)
GGO: 101132886(DLG1)
PON: 100444925(DLG1)
NLE: 100603856(DLG1)
MCC: 709572(DLG1)
MCF: 102123600(DLG1)
CSAB: 103241973(DLG1)
RRO: 104676365(DLG1)
RBB: 108530521(DLG1)
CJC: 100401687(DLG1)
SBQ: 101032502(DLG1)
MMU: 13383(Dlg1)
RNO: 25252(Dlg1)
CGE: 100774630(Dlg1)
NGI: 103738531(Dlg1)
HGL: 101716409(Dlg1)
OCU: 100339253(DLG1)
TUP: 102468222(DLG1)
CFA: 488036(DLG1)
AML: 100481489(DLG1)
UMR: 103678920(DLG1)
ORO: 101363847(DLG1)
FCA: 101084051(DLG1)
PTG: 102971040(DLG1)
AJU: 106976354(DLG1)
BTA: 785291(DLG1)
BOM: 102284602(DLG1)
BIU: 109562672(DLG1)
PHD: 102319946(DLG1)
CHX: 102178485(DLG1)
OAS: 101103028(DLG1)
SSC: 100157729(DLG1)
CFR: 102508504(DLG1)
CDK: 105101276(DLG1)
BACU: 103001527(DLG1)
LVE: 103079722(DLG1)
OOR: 101270560(DLG1)
ECB: 100060094(DLG1)
EPZ: 103559183
EAI: 106848317(DLG1)
MYB: 102251241(DLG1)
MYD: 102771948(DLG1)
HAI: 109387512(DLG1)
RSS: 109443268(DLG1)
PALE: 102887557(DLG1)
LAV: 100662117(DLG1)
TMU: 101353387
MDO: 100017371(DLG1)
SHR: 100924037(DLG1)
OAA: 100082103(DLG1)
GGA: 424890(DLG1)
MGP: 100545279(DLG1)
CJO: 107318156(DLG1)
APLA: 101798182(DLG1)
ACYG: 106039234(DLG1)
TGU: 100220198(DLG1)
GFR: 102034754(DLG1)
FAB: 101813757(DLG1)
PHI: 102113578(DLG1)
PMAJ: 107208781(DLG1)
CCW: 104693473(DLG1)
FPG: 101914926(DLG1)
FCH: 102052280(DLG1)
CLV: 102091278(DLG1)
EGZ: 104127125(DLG1)
AAM: 106485876(DLG1)
ASN: 102388205(DLG1)
AMJ: 102560983(DLG1)
PSS: 102453762(DLG1)
CMY: 102946800(DLG1)
CPIC: 101941940(DLG1)
PVT: 110087113
PBI: 103061777
GJA: 107125637(DLG1)
XTR: 733937(dlg1)
NPR: 108795997(DLG1)
DRE: 114446(dlg1) 497648(dlg1l)
IPU: 108271975 108280564(DLG1)
TRU: 101061618 101067056(dlg1)
NCC: 104946575(dlg1)
MZE: 101468517 101473605(dlg1)
PRET: 103460621 103463088(dlg1)
NFU: 107383683 107392960(dlg1)
CSEM: 103396276(dlg1) 103396862
SFM: 108921599(dlg1) 108939922
LCM: 102359739(DLG1)
CMK: 103181252(dlg1)
CIN: 100177284
APLC: 110981686
SKO: 100329000(SAP97)
DME: Dmel_CG1725(dlg1)
AAG: 23687408
AME: 724292
BIM: 100747372
BTER: 100643982
SOC: 105201229
AEC: 105146407
ACEP: 105627778
PBAR: 105425276
HST: 105190839
CFO: 105253961
LHU: 105677469
PGC: 109854966
TCA: 663521
BMOR: 101744274
PXY: 105388463
ZNE: 110831408
FCD: 110852265
TUT: 107363121
CEL: CELE_C25F6.2(dlg-1)
CBR: CBG14691(Cbr-dlg-1)
BMY: Bm1_32060
TSP: Tsp_08375
CRG: 105346688
MYI: 110465311
OBI: 106876507
EPA: 110232068
ADF: 107337951
HMG: 100209202
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Round JL, Humphries LA, Tomassian T, Mittelstadt P, Zhang M, Miceli MC
  Title
Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factors.
  Journal
Nat Immunol 8:154-61 (2007)
DOI:10.1038/ni1422
Reference
PMID:8678991
  Authors
Burgess DL, Rafael JA, Meisler MH, Chamberlain JS
  Title
Dlgh1, a mouse homolog of the drosophila discs-large gene, is located on chromosome 16.
  Journal
Mamm Genome 7:623-4 (1996)
DOI:10.1007/s003359900187
  Sequence
[mmu:13383]
Reference
  Authors
Manneville JB, Jehanno M, Etienne-Manneville S
  Title
Dlg1 binds GKAP to control dynein association with microtubules, centrosome positioning, and cell polarity.
  Journal
J Cell Biol 191:585-98 (2010)
DOI:10.1083/jcb.201002151
Reference
  Authors
Ishidate T, Matsumine A, Toyoshima K, Akiyama T
  Title
The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase.
  Journal
Oncogene 19:365-72 (2000)
DOI:10.1038/sj.onc.1203309

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