KEGG   ORTHOLOGY: K12182Help
Entry
K12182                      KO                                     

Name
HGS, HRS, VPS27
Definition
hepatocyte growth factor-regulated tyrosine kinase substrate
Pathway
ko04144  Endocytosis
ko04145  Phagosome
Module
M00408  ESCRT-0 complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K12182  HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate
   04145 Phagosome
    K12182  HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Protein processing
    M00408  ESCRT-0 complex
     K12182  HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate
Membrane trafficking [BR:ko04131]
 Endosome - Lysosome transport
  Endosomal sorting complexes required for transport (ESCRT)
   ESCRT-0 complex
    K12182  HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate
BRITE hierarchy
Genes
HSA: 9146(HGS)
PTR: 454966(HGS)
PPS: 100995389(HGS)
GGO: 101152742(HGS)
PON: 100447151(HGS)
NLE: 100595673(HGS)
MCC: 714385(HGS)
MCF: 102130302(HGS)
CSAB: 103243727(HGS)
RRO: 104654960(HGS)
RBB: 108534113(HGS)
CJC: 100391698(HGS)
SBQ: 101048011(HGS)
MMU: 15239(Hgs)
RNO: 56084(Hgs)
CGE: 100765681(Hgs) 103158909
NGI: 103730308(Hgs)
HGL: 101706323(Hgs)
CCAN: 109702480(Hgs)
TUP: 102496792(HGS)
CFA: 483367(HGS)
AML: 100471988(HGS)
UMR: 103665999(HGS)
ORO: 101380692(HGS)
FCA: 101088702(HGS)
PTG: 102962567
AJU: 106987393(HGS)
BTA: 511582(HGS)
BOM: 102284452(HGS)
BIU: 109573715(HGS)
PHD: 102333438(HGS)
CHX: 102181336(HGS)
OAS: 101116491(HGS)
SSC: 106508767(HGS)
CFR: 102522502(HGS)
CDK: 105105710(HGS)
BACU: 103007591(HGS)
LVE: 103084443(HGS)
OOR: 101272954(HGS)
ECB: 100055613(HGS)
EPZ: 103551090(HGS)
EAI: 106845832(HGS)
MYB: 102264210(HGS)
MYD: 102757452(HGS)
HAI: 109393058(HGS)
RSS: 109449351(HGS)
PALE: 102889403(HGS)
LAV: 100677768(HGS)
TMU: 101341062
MDO: 100025702(HGS)
SHR: 100926759(HGS)
OAA: 100091110(HGS)
GGA: 428675(HGS)
MGP: 100546212(HGS)
CJO: 107322130(HGS)
APLA: 101799282(HGS)
ACYG: 106046753(HGS)
TGU: 100230661(HGS)
GFR: 102033465(HGS)
FAB: 101821215(HGS)
PHI: 102106831(HGS)
PMAJ: 107212540(HGS)
CCW: 104698230(HGS)
FPG: 101916388(HGS)
FCH: 102053104(HGS)
CLV: 102092912(HGS)
EGZ: 104131163
AAM: 106487142(HGS)
ASN: 102385241(HGS)
AMJ: 102561640(HGS)
PSS: 102454916(HGS)
CMY: 102936133(HGS)
CPIC: 101933189(HGS)
ACS: 100566601(hgs)
PVT: 110090507(HGS)
PBI: 103065558(HGS)
GJA: 107123314(HGS)
XLA: 399007(hgs.L)
XTR: 549267(hgs)
NPR: 108784759(HGS)
DRE: 334175(hgs)
SRX: 107711191(hgs) 107722883
SGH: 107599295
IPU: 108256888(hgs)
AMEX: 103027389(hgs)
TRU: 101075142(hgs)
LCO: 104918631(hgs)
NCC: 104960317(hgs)
MZE: 101466364 101468021(hgs)
OLA: 101168120(hgs)
XMA: 102228811(hgs)
PRET: 103468795(hgs)
NFU: 107395391(hgs)
CSEM: 103392699(hgs)
LCF: 108902686(hgs)
HCQ: 109532511(hgs)
BPEC: 110166460(hgs)
ELS: 105029614(hgs)
LCM: 102354207(HGS)
CMK: 103175587(hgs)
CIN: 778843(zf(fyve)-11)
SPU: 578315
APLC: 110978555
SKO: 100378364
DME: Dmel_CG2903(Hrs)
DSI: Dsimw501_GD23175(Dsim_GD23175)
MDE: 101898678
AAG: 5566357
AME: 410510(Hrs)
BIM: 100741964
BTER: 100646438
SOC: 105195021
AEC: 105154858
ACEP: 105620786
PBAR: 105429963
HST: 105186135
CFO: 105256872
LHU: 105676695
PGC: 109862016
NVI: 100123769
TCA: 656221
DPA: 109544450
NVL: 108560621
BMOR: 101738908
PMAC: 106713234
PRAP: 110992154
DNX: 107170148
ZNE: 110837649
FCD: 110849423
TUT: 107363218
CEL: CELE_C07G1.5(hgrs-1)
CBR: CBG01567(Cbr-hgrs-1)
BMY: Bm1_29500
TSP: Tsp_03155
CRG: 105333900
MYI: 110453672
OBI: 106883725
LAK: 106176866
SHX: MS3_09602
EPA: 110239950
ADF: 107345925
HMG: 101236981
PXB: 108866918
SCE: YNR006W(VPS27)
ERC: Ecym_2123
KMX: KLMA_20419(VPS27)
NCS: NCAS_0G01000(NCAS0G01000)
NDI: NDAI_0F01130(NDAI0F01130)
TPF: TPHA_0H02110(TPHA0H02110)
TBL: TBLA_0A02410(TBLA0A02410)
TDL: TDEL_0A07090(TDEL0A07090)
KAF: KAFR_0F00930(KAFR0F00930)
PIC: PICST_36619(VPS27)
CAL: CAALFM_C100750CA(VPS27)
CAUR: QG37_01051
SLB: AWJ20_3966(VPS27)
NCR: NCU04015
NTE: NEUTE1DRAFT148795(NEUTE1DRAFT_148795)
MGR: MGG_04958
MAW: MAC_02650
MAJ: MAA_02152
CMT: CCM_05070
MBE: MBM_05153
ANI: AN2071.2
ANG: ANI_1_600094(An11g04400)
CIM: CIMG_12799(CIMG01226)
ABE: ARB_05268
TVE: TRV_02307
PTE: PTT_11026
SPO: SPAC19A8.05c(sst4)
CNE: CNE03710
CNB: CNBE3700
ABP: AGABI1DRAFT65855(AGABI1DRAFT_65855)
ABV: AGABI2DRAFT190088(AGABI2DRAFT_190088)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Miura S, Takeshita T, Asao H, Kimura Y, Murata K, Sasaki Y, Hanai JI, Beppu H, Tsukazaki T, Wrana JL, Miyazono K, Sugamura K
  Title
Hgs (Hrs), a FYVE domain protein, is involved in Smad signaling through cooperation with SARA.
  Journal
Mol Cell Biol 20:9346-55 (2000)
DOI:10.1128/MCB.20.24.9346-9355.2000
  Sequence
[mmu:15239]
Reference
  Authors
Katzmann DJ, Stefan CJ, Babst M, Emr SD
  Title
Vps27 recruits ESCRT machinery to endosomes during MVB sorting.
  Journal
J Cell Biol 162:413-23 (2003)
DOI:10.1083/jcb.200302136
  Sequence
[sce:YNR006W]

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