KEGG   ORTHOLOGY: K12311Help
Entry
K12311                      KO                                     

Name
MAN2B1, LAMAN
Definition
lysosomal alpha-mannosidase [EC:3.2.1.24]
Pathway
ko00511  Other glycan degradation
ko04142  Lysosome
Disease
H00139  alpha-Mannosidosis
H00422  Glycoproteinoses
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00511 Other glycan degradation
    K12311  MAN2B1, LAMAN; lysosomal alpha-mannosidase
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    K12311  MAN2B1, LAMAN; lysosomal alpha-mannosidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.24  alpha-mannosidase
     K12311  MAN2B1, LAMAN; lysosomal alpha-mannosidase
BRITE hierarchy
Other DBs
RN: R08717 R08718
GO: 0004559
CAZy: GH38
Genes
HSA: 4125(MAN2B1)
PTR: 455745(MAN2B1)
PPS: 100977668(MAN2B1)
GGO: 101136007(MAN2B1)
PON: 100174476(MAN2B1)
NLE: 100598622(MAN2B1)
MCC: 716173(MAN2B1)
MCF: 102137710(MAN2B1)
CSAB: 103233978(MAN2B1)
RRO: 104661102(MAN2B1)
RBB: 108539608(MAN2B1)
CJC: 100395073(MAN2B1)
SBQ: 101050078(MAN2B1)
MMU: 17159(Man2b1)
RNO: 361378(Man2b1)
CGE: 100766505(Man2b1)
NGI: 103751895(Man2b1)
HGL: 101705792(Man2b1)
CCAN: 109681246(Man2b1) 109685194
TUP: 102483853(MAN2B1)
CFA: 484932(MAN2B1)
AML: 100470947(MAN2B1)
UMR: 103682159(MAN2B1)
ORO: 101367441(MAN2B1)
FCA: 493697(MAN2B1)
PTG: 102971102(MAN2B1)
AJU: 106985939(MAN2B1)
BTA: 282272(MAN2B1)
BOM: 102269568(MAN2B1)
BIU: 109561547(MAN2B1)
PHD: 102337252(MAN2B1)
CHX: 102183410(MAN2B1)
OAS: 101102146(MAN2B1)
SSC: 100518647(MAN2B1)
CFR: 102508436(MAN2B1)
CDK: 105104070(MAN2B1)
BACU: 102999783(MAN2B1)
LVE: 103088076(MAN2B1)
OOR: 101285368(MAN2B1)
ECB: 100064359(MAN2B1)
EAI: 106826920(MAN2B1)
MYB: 102255151(MAN2B1)
MYD: 102755574(MAN2B1)
HAI: 109394253(MAN2B1)
RSS: 109454954(MAN2B1)
PALE: 102898106(MAN2B1)
LAV: 100658867(MAN2B1) 100664557
MDO: 100010377(MAN2B1)
SHR: 100930413(MAN2B1)
OAA: 103170598(MAN2B1)
CJO: 107307162(MAN2B1)
SCAN: 108964243
PHI: 102101310(MAN2B1)
CCAE: 111945477
FPG: 106112399(MAN2B1)
NNI: 104009709(MAN2B1)
AAM: 106498060(MAN2B1)
ASN: 102376538(MAN2B1)
AMJ: 102562074(MAN2B1)
PSS: 102446502(MAN2B1)
CMY: 102934391(MAN2B1)
CPIC: 101942520(MAN2B1)
ACS: 100557773(man2b1)
PVT: 110082637(MAN2B1)
PBI: 103064652(MAN2B1)
PMUR: 107286892(MAN2B1)
GJA: 107114373(MAN2B1)
XLA: 108711713(man2b1.L)
XTR: 779924(man2b1)
NPR: 108794969(MAN2B1)
DRE: 541519(man2b1)
SRX: 107737232(man2b1) 107751149
IPU: 108259485(man2b1)
PHYP: 113524272(man2b1)
AMEX: 103033201(man2b1) 111188897
TRU: 101073393(man2b1)
LCO: 104925274(man2b1)
NCC: 104942255(man2b1)
MZE: 101487837(man2b1) 112434922
OLA: 101168422(man2b1)
XMA: 102232163(man2b1)
PRET: 103480745(man2b1)
NFU: 107391285(man2b1)
KMR: 108240322(man2b1)
LCF: 108880838(man2b1)
SDU: 111235904(man2b1)
HCQ: 109511053(man2b1)
BPEC: 110172144(man2b1)
MALB: 109970346(man2b1)
SASA: 101448032(man2b1) 106590633
OTW: 112240415
SALP: 112078491(man2b1)
ELS: 105012090(man2b1)
SFM: 108927502(man2b1)
LCM: 102355373(MAN2B1)
CIN: 100176799
SPU: 591324
APLC: 110975939
DME: Dmel_CG5322(LManI) Dmel_CG6206(LManII) Dmel_CG9463(LManIII) Dmel_CG9465(LManIV) Dmel_CG9466(LManV) Dmel_CG9468(LManVI)
DSI: Dsimw501_GD22254(Dsim_GD22254) Dsimw501_GD22379(Dsim_GD22379) Dsimw501_GD22380(Dsim_GD22380) Dsimw501_GD22381(Dsim_GD22381) Dsimw501_GD22383(Dsim_GD22383) Dsimw501_GD23708(Dsim_GD23708)
AME: 552249
BIM: 100743817
BTER: 100651034
SOC: 105208102
MPHA: 105837315
AEC: 105154650
ACEP: 105622460
PBAR: 105432214
HST: 105190275
DQU: 106751241
CFO: 105250629
LHU: 105672298
PGC: 109858269
OBO: 105285665
PCF: 106789636
NVI: 100120019
ZNE: 110837258
FCD: 110842868
CEL: CELE_F55D10.1(aman-1)
CBR: CBG14532(Cbr-aman-1)
BMY: Bm1_32610
LAK: 106168249
ADF: 107336032
SPIS: 111329016
HMG: 100212242
DDI: DDB_G0292206(manA)
DFA: DFA_00378(manA) DFA_02102 DFA_10499(manF) DFA_11726(manC)
SMIN: v1.2.017760.t1(symbB.v1.2.017760.t1)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Venkatesan M, Kuntz DA, Rose DR
  Title
Human lysosomal alpha-mannosidases exhibit different inhibition and metal binding properties.
  Journal
Protein Sci 18:2242-51 (2009)
DOI:10.1002/pro.235
  Sequence
[hsa:4125]

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