KEGG   ORTHOLOGY: K12329Help
Entry
K12329                      KO                                     

Name
PPP1R12B, MYPT2
Definition
protein phosphatase 1 regulatory subunit 12B
Pathway
ko04270  Vascular smooth muscle contraction
ko04510  Focal adhesion
ko04810  Regulation of actin cytoskeleton
ko04921  Oxytocin signaling pathway
ko05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cellular community - eukaryotes
   04510 Focal adhesion
    K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
  Cell motility
   04810 Regulation of actin cytoskeleton
    K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
  Circulatory system
   04270 Vascular smooth muscle contraction
    K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
Protein phosphatases and associated proteins [BR:ko01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K12329  PPP1R12B, MYPT2; protein phosphatase 1 regulatory subunit 12B
BRITE hierarchy
Genes
HSA: 4660(PPP1R12B)
PTR: 457629(PPP1R12B)
PPS: 100970244(PPP1R12B)
GGO: 101133217(PPP1R12B)
PON: 103890237(PPP1R12B)
NLE: 100592546 100593768(PPP1R12B)
MCC: 705775(PPP1R12B)
MCF: 102121021(PPP1R12B)
CSAB: 103230309(PPP1R12B)
RRO: 104674509(PPP1R12B)
RBB: 108545061(PPP1R12B)
CJC: 100404247(PPP1R12B)
SBQ: 101053159(PPP1R12B)
MMU: 329251(Ppp1r12b)
RNO: 304813(Ppp1r12b)
CGE: 100753601(Ppp1r12b)
NGI: 103731836(Ppp1r12b)
HGL: 101711489(Ppp1r12b)
CCAN: 109690053(Ppp1r12b) 109690054
OCU: 100356902(PPP1R12B)
TUP: 102500634(PPP1R12B)
CFA: 490230(PPP1R12B)
AML: 100470069(PPP1R12B) 100480266
ORO: 101369772(PPP1R12B)
FCA: 101098766(PPP1R12B)
PTG: 102950482(PPP1R12B)
AJU: 106973120(PPP1R12B)
BTA: 107131237(PPP1R12B)
BOM: 102286584(PPP1R12B)
PHD: 102329074 102335151(PPP1R12B)
CHX: 102181773(PPP1R12B)
SSC: 100525832(PPP1R12B)
CFR: 102506936(PPP1R12B)
CDK: 105105927(PPP1R12B)
BACU: 103012518(PPP1R12B)
LVE: 103071840(PPP1R12B)
OOR: 101289221(PPP1R12B)
ECB: 100063928(PPP1R12B)
EPZ: 103561986(PPP1R12B)
EAI: 106840263(PPP1R12B)
MYB: 102263913(PPP1R12B)
MYD: 102762227(PPP1R12B)
HAI: 109380462(PPP1R12B)
RSS: 109457731(PPP1R12B)
PALE: 102879733(PPP1R12B)
LAV: 100675940(PPP1R12B)
MDO: 100011797(PPP1R12B)
SHR: 100925265(PPP1R12B)
OAA: 100077407(PPP1R12B)
GGA: 395478(PPP1R12B)
MGP: 100545452 104914452(PPP1R12B)
CJO: 107324641(PPP1R12B)
APLA: 101797997(PPP1R12B)
ACYG: 106045852 106045864(PPP1R12B)
TGU: 100224964(PPP1R12B)
FAB: 101813313(PPP1R12B) 101818016
PHI: 102113018(PPP1R12B)
PMAJ: 107214882(PPP1R12B)
CCW: 104692457(PPP1R12B)
FPG: 101915795(PPP1R12B)
FCH: 102059378(PPP1R12B)
AAM: 106500257(PPP1R12B)
ASN: 102387200(PPP1R12B)
AMJ: 102561475(PPP1R12B)
PSS: 102450232(PPP1R12B)
CMY: 102943607 102943827(PPP1R12B)
CPIC: 101931457(PPP1R12B) 103306709
ACS: 100566099(ppp1r12b)
PVT: 110073397(PPP1R12B)
PBI: 103051701(PPP1R12B)
XLA: 108708153(ppp1r12b.L)
XTR: 780217(ppp1r12b)
NPR: 108792790
DRE: 101885790
CCAR: 109081823
IPU: 108276302
AMEX: 103026736
NCC: 104944116
LCM: 102364878
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Grassie ME, Moffat LD, Walsh MP, MacDonald JA
  Title
The myosin phosphatase targeting protein (MYPT) family: a regulated mechanism for achieving substrate specificity of the catalytic subunit of protein phosphatase type 1delta.
  Journal
Arch Biochem Biophys 510:147-59 (2011)
DOI:10.1016/j.abb.2011.01.018

DBGET integrated database retrieval system