KEGG   ORTHOLOGY: K12344Help
Entry
K12344                      KO                                     

Name
SRD5A2
Definition
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Pathway
ko00140  Steroid hormone biosynthesis
ko05215  Prostate cancer
Disease
H00608  46,XY disorder of sex development due to testosterone secretion defect
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K12344  SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2
 09160 Human Diseases
  09162 Cancers: Specific types
   05215 Prostate cancer
    K12344  SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     K12344  SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2
BRITE hierarchy
Other DBs
RN: R02208 R02497 R08954 R10242
GO: 0047751
Genes
HSA: 6716(SRD5A2)
PTR: 100614992(SRD5A2)
PPS: 100986960(SRD5A2)
GGO: 101138758(SRD5A2)
PON: 100454013(SRD5A2)
NLE: 100597634(SRD5A2)
MCC: 705676(SRD5A2)
MCF: 102115639(SRD5A2)
CSAB: 103220536(SRD5A2)
RRO: 104669588(SRD5A2)
RBB: 108516633(SRD5A2)
CJC: 100415292(SRD5A2)
SBQ: 101043426(SRD5A2)
MMU: 94224(Srd5a2)
RNO: 64677(Srd5a2)
CGE: 100766917(Srd5a2)
NGI: 103748375(Srd5a2)
HGL: 101708836(Srd5a2)
CCAN: 109702049(Srd5a2)
OCU: 100343882(SRD5A2)
TUP: 102478179(SRD5A2)
CFA: 403715(SRD5A2)
AML: 100466687(SRD5A2)
UMR: 103671605(SRD5A2)
ORO: 101376466(SRD5A2)
FCA: 101086898(SRD5A2)
PTG: 102953790(SRD5A2)
AJU: 113592483(SRD5A2)
BTA: 527024(SRD5A2)
BOM: 102271230(SRD5A2)
BIU: 109565724(SRD5A2)
PHD: 102326516(SRD5A2)
CHX: 102187232(SRD5A2)
OAS: 100820756(SRD5A2)
SSC: 397048(SRD5A2)
CFR: 102523831(SRD5A2)
CDK: 105095594(SRD5A2)
BACU: 103005044
LVE: 103084942(SRD5A2)
OOR: 101284817(SRD5A2)
ECB: 100070655(SRD5A2)
EPZ: 103561662(SRD5A2)
EAI: 106847216(SRD5A2)
MYB: 102242056(SRD5A2)
MYD: 102773080(SRD5A2)
HAI: 109388788(SRD5A2)
RSS: 109437897(SRD5A2)
PALE: 102884992(SRD5A2)
TMU: 101348818
MDO: 100031489(SRD5A2)
SHR: 100934924(SRD5A2)
OAA: 100078235(SRD5A2)
GGA: 772291(SRD5A2)
MGP: 100546745(SRD5A2)
CJO: 107311306(SRD5A2)
APLA: 101799397(SRD5A2)
ACYG: 106049776(SRD5A2)
TGU: 100225484(SRD5A2)
SCAN: 103821781(SRD5A2)
GFR: 102038097(SRD5A2)
FAB: 101808258(SRD5A2)
PHI: 102108406(SRD5A2)
PMAJ: 107201346(SRD5A2)
CCAE: 111926994(SRD5A2)
CCW: 104684391(SRD5A2)
FPG: 101919492(SRD5A2)
FCH: 102046391(SRD5A2)
CLV: 102085278(SRD5A2)
EGZ: 104124808(SRD5A2)
NNI: 104012069(SRD5A2)
ACUN: 113478727(SRD5A2)
AAM: 106485465(SRD5A2)
ASN: 102380562(SRD5A2)
AMJ: 102573116(SRD5A2)
PSS: 102451701(SRD5A2)
CMY: 102936118(SRD5A2)
CPIC: 101939421
ACS: 100563846(srd5a2)
PVT: 110076132(SRD5A2)
PBI: 103048475(SRD5A2)
PMUR: 107302483(SRD5A2)
GJA: 107108075(SRD5A2)
XLA: 108716702(srd5a2.L) 108717848(srd5a2.S)
XTR: 549867(srd5a2)
NPR: 108789853(SRD5A2)
DRE: 550388(srd5a2b) 550398(srd5a2a)
IPU: 108258997(srd5a2)
PHYP: 113537369(srd5a2)
AMEX: 103036227(srd5a2) 103043083
EEE: 113579627(srd5a2)
TRU: 101066856(srd5a2)
LCO: 104918211(srd5a2) 104939523
XMA: 102228249 102230435(srd5a2)
NFU: 107375448(srd5a2) 107394001
KMR: 108229061 108248141(srd5a2)
CSEM: 103383286
LCF: 108882308 108885816(srd5a2)
SDU: 111220716(srd5a2) 111237591
HCQ: 109516280(srd5a2)
BPEC: 110153623 110157251(srd5a2)
MALB: 109971818(srd5a2)
SASA: 100196185(s5a2) 106564819(S5A2)
LCM: 102355026(SRD5A2)
CMK: 103181748(srd5a2)
HMG: 100197205
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Caglayan AO, Dundar M, Tanriverdi F, Baysal NA, Unluhizarci K, Ozkul Y, Borlu M, Batukan C, Kelestimur F
  Title
Idiopathic hirsutism: local and peripheral expression of aromatase (CYP19A) and 5alpha-reductase genes (SRD5A1 and SRD5A2).
  Journal
Fertil Steril 96:479-82 (2011)
DOI:10.1016/j.fertnstert.2011.05.040

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