KEGG   ORTHOLOGY: K12394
Entry
K12394                      KO                                     
Symbol
AP1S1_2
Name
AP-1 complex subunit sigma 1/2
Pathway
map04142  Lysosome
map05170  Human immunodeficiency virus 1 infection
Disease
H00658  Syndromic X-linked mental retardation
H02220  MEDNIK syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    K12394  AP1S1_2; AP-1 complex subunit sigma 1/2
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K12394  AP1S1_2; AP-1 complex subunit sigma 1/2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12394  AP1S1_2; AP-1 complex subunit sigma 1/2
Membrane trafficking [BR:ko04131]
 Endosome - Golgi transport
  Others
   AP-1 complex
    K12394  AP1S1_2; AP-1 complex subunit sigma 1/2
Genes
HSA: 1174(AP1S1) 8905(AP1S2)
PTR: 737479(AP1S2) 740971(AP1S1)
PPS: 100970147(AP1S1) 100983447(AP1S2) 117980273 117980473
GGO: 101143987(AP1S2) 101148077(AP1S1)
PON: 100435994(AP1S2) 100437759(AP1S1)
NLE: 100585675(AP1S1) 100587241(AP1S2)
MCC: 713244(AP1S2) 719569(AP1S1)
MCF: 102114826(AP1S1) 102132905(AP1S2)
CSAB: 103231646(AP1S2) 103246696(AP1S1)
CATY: 105574677(AP1S2) 105593414(AP1S1)
PANU: 101004796(AP1S2) 101019240(AP1S1)
TGE: 112615380(AP1S2) 112620794(AP1S1)
RRO: 104657300(AP1S2) 104681184(AP1S1)
RBB: 108518942(AP1S1) 108540105
TFN: 117072533(AP1S1) 117077256(AP1S2)
PTEH: 111527923(AP1S1) 111531641(AP1S2)
CJC: 100384920(AP1S1) 100411052(AP1S2)
SBQ: 101027487 101045707(AP1S1) 101047405(AP1S2)
CSYR: 103250982(AP1S1) 103251574(AP1S2)
MMUR: 105868414(AP1S1) 105882406(AP1S2)
OGA: 100947667(AP1S2) 100961554(AP1S1)
MMU: 108012(Ap1s2) 11769(Ap1s1)
MCAL: 110286699(Ap1s2) 110305364(Ap1s1)
MPAH: 110312865(Ap1s1) 110313383(Ap1s2)
RNO: 302671(Ap1s2) 360785(Ap1s1)
MCOC: 116068577(Ap1s1) 116090393(Ap1s2)
MUN: 110565661 110566256(Ap1s1)
CGE: 100759417(Ap1s1) 100768456(Ap1s2)
PLEU: 114705708(Ap1s2) 114710321(Ap1s1)
CPOC: 100724571(Ap1s1) 100732251(Ap1s2)
CCAN: 109691427(Ap1s2) 109692818(Ap1s1)
DORD: 105997343(Ap1s1) 105997666(Ap1s2)
DSP: 122108505(Ap1s2) 122113828(Ap1s1)
OCU: 100351856(AP1S2) 100357188(AP1S1)
OPI: 101523034 101526279(AP1S2) 101532865(AP1S1)
TUP: 102474217 102477765(AP1S1) 102482573(AP1S2)
CFA: 100688000(AP1S1) 611468(AP1S2)
VVP: 112912560 112919148(AP1S2) 112935719(AP1S1)
VLG: 121483109(AP1S2) 121487839(AP1S1)
AML: 100465621(AP1S2) 100483720(AP1S1)
UMR: 103656543 103668129(AP1S2) 103670126(AP1S1)
UAH: 113242279(AP1S2) 113248843 113267838(AP1S1)
UAR: 123777290(AP1S1) 123785088 123793871(AP1S2)
MPUF: 101675629(AP1S2) 101686492(AP1S1)
ORO: 101363008(AP1S2) 101366143 101382714(AP1S1)
EJU: 114200437(AP1S2) 114214447(AP1S1)
ZCA: 113931012(AP1S2) 113932887(AP1S1) 118356610
MLX: 117999440(AP1S1) 118007046(AP1S2)
FCA: 101081183(AP1S1) 101096540(AP1S2)
PYU: 121017656(AP1S1) 121025671(AP1S2)
PBG: 122471314(AP1S1) 122477274(AP1S2)
PTG: 102966106(AP1S2) 102972027(AP1S1)
PPAD: 109248325(AP1S2) 109250527(AP1S1)
AJU: 106983455(AP1S2) 106988111(AP1S1)
HHV: 120232929(AP1S2) 120239266(AP1S1)
BTA: 616331(AP1S2) 768053(AP1S1)
BOM: 102273819(AP1S2) 102276355(AP1S1)
BIU: 109555179(AP1S2) 109578775(AP1S1)
BBUB: 102391704(AP1S1) 102394665(AP1S2)
CHX: 102170040(AP1S1) 102177702(AP1S2)
OAS: 101104633(AP1S2) 101122493(AP1S1)
ODA: 120878992(AP1S1) 120882553(AP1S2)
CCAD: 122433301(AP1S1) 122434825(AP1S2)
SSC: 100517795(AP1S2) 100624239(AP1S1)
CFR: 102505439(AP1S1) 102507282(AP1S2)
CBAI: 105067243(AP1S1) 105079300(AP1S2)
CDK: 105092392(AP1S1) 105094988(AP1S2)
VPC: 102529996(AP1S1) 102535486(AP1S2)
BACU: 103003025(AP1S2) 103019158(AP1S1)
LVE: 103085301(AP1S2) 103091350(AP1S1)
OOR: 101273362(AP1S1) 101282972(AP1S2)
DLE: 111168891(AP1S2) 111181996(AP1S1)
PCAD: 102978978(AP1S2) 102995531(AP1S1)
PSIU: 116740945(AP1S1) 116747454(AP1S2)
ECB: 100060194(AP1S1) 100629680(AP1S2)
EPZ: 103541184(AP1S1) 103543754
EAI: 106839299(AP1S1) 106841572(AP1S2)
MYB: 102252720(AP1S2) 102263153(AP1S1)
MYD: 102761837(AP1S2) 102771289(AP1S1)
MMYO: 118653738(AP1S2) 118656369(AP1S1)
MLF: 102418013(AP1S2) 102419274(AP1S1)
MNA: 107526506(AP1S1) 107529515(AP1S2)
PKL: 118703391(AP1S1) 118719795(AP1S2)
HAI: 109384977(AP1S1) 109395427(AP1S2)
DRO: 112313392(AP1S2) 112315007(AP1S1)
SHON: 118992848(AP1S1) 118993799(AP1S2)
AJM: 119044723(AP1S1) 119058324(AP1S2)
PDIC: 114494621(AP1S1) 114504636(AP1S2)
PHAS: 123806330(AP1S1) 123830040(AP1S2)
MMF: 118635597(AP1S2) 118641879(AP1S1)
RFQ: 117023622(AP1S2) 117024423(AP1S1)
PALE: 102879773(AP1S1) 102886905(AP1S2)
PGIG: 120591669(AP1S1) 120594302(AP1S2)
PVP: 105294005(AP1S2) 105299723(AP1S1)
RAY: 107497186(AP1S2) 107511773(AP1S1)
MJV: 108395146(AP1S2) 108395793(AP1S1)
TOD: 119241564(AP1S1) 119244450 119246311(AP1S2)
SARA: 101538908(AP1S2) 101548182(AP1S1)
LAV: 100662591(AP1S2) 100673211(AP1S1)
DNM: 101438854(AP1S2) 101445073(AP1S1)
MDO: 100016849(AP1S2) 100016919(AP1S1)
SHR: 100914815(AP1S2) 100916131(AP1S1)
PCW: 110194268(AP1S1) 110222427(AP1S2)
OAA: 100085289(AP1S2) 114808195(AP1S1)
GGA: 418621(AP1S2)
PCOC: 116230733(AP1S2) 116239848
MGP: 100541495(AP1S2)
CJO: 107307418(AP4M1) 107325516(AP1S2)
NMEL: 110391354(AP1S1) 110404956(AP1S2)
APLA: 101790911(AP1S2)
ACYG: 106037827(AP1S2)
AFUL: 116487957(AP1S2)
TGU: 100229865(AP1S2) 115492730(AP1S1)
LSR: 110471611(AP1S2)
SCAN: 103815824(AP1S2)
OTC: 121332970 121342239(AP1S2)
PRUF: 121349929 121356223(AP1S2)
GFR: 102033701(AP1S1) 102036894(AP1S2)
FAB: 101813784(AP1S2)
PHI: 102108850(AP1S2)
PMAJ: 107202983(AP1S2)
CCAE: 111922843(AP1S2) 111945801
CCW: 104686170(AP1S2)
ETL: 114068267(AP1S2)
ZAB: 102066551(AP1S2)
FPG: 101911258(AP1S2)
FCH: 102046155(AP1S2)
CLV: 102093039(AP1S2) 102094882
NNI: 104022529(AP1S2)
ACUN: 113477925(AP1S2)
TALA: 104366289(AP1S2)
PADL: 103918205(AP1S2)
ACHC: 115334712(AP1S2) 115338408
AAM: 106491903(AP1S2)
AROW: 112976190(AP1S2)
NPD: 112943986(AP1S2) 112957822
DNE: 112995638(AP1S2)
ASN: 102369930(AP1S1) 102387703(AP1S2)
AMJ: 102560773(AP1S1) 102567825(AP1S2)
CPOO: 109306026(AP1S2)
GGN: 109302633(AP1S2)
PSS: 102453253(AP1S2) 102463976(AP1S1)
CMY: 102937990(AP1S2)
CPIC: 101949115(AP1S2) 101950293(AP1S1)
TST: 117869463(AP1S2)
CABI: 116817069(AP1S1) 116821842(AP1S2)
MRV: 120375754(AP1S2) 120381831(AP1S1)
ACS: 100555595(ap1s2)
PVT: 110075447(AP1S2) 110077426(AP1S1)
SUND: 121924782(AP1S2) 121933966(AP1S1)
PBI: 103062893(AP1S1) 103067167(AP1S2)
PMUR: 107285054(AP1S1) 107296335(AP1S2)
TSR: 106551757(AP1S1) 106553042(AP1S2)
PGUT: 117673435(AP1S1) 117675800(AP1S2)
VKO: 123021750(AP1S1) 123023426(AP1S2)
PMUA: 114582470(AP1S1) 114596260(AP1S2)
ZVI: 118085040(AP1S2) 118095413(AP1S1)
GJA: 107113526 107115854(AP1S2)
STOW: 125431656(AP1S2) 125445264(AP1S1)
XLA: 108703509(ap1s1.S) 108707923(ap1s2.L) 399079(ap1s1.L) 495185(ap1s2.S)
XTR: 394963(ap1s1) 733931(ap1s2)
NPR: 108792320(AP1S2)
RTEM: 120933480(AP1S1)
BBUF: 120986515(AP1S1) 120994626(AP1S2)
BGAR: 122927165(AP1S1) 122930375(AP1S2)
DRE: 327237(ap1s2) 337771(zgc:162858) 393279(ap1s1)
PPRM: 120468960(ap1s2) 120471166 120483654(ap1s1)
MAMB: 125257101(ap1s2) 125260331 125264608(ap1s1)
IPU: 108267920(ap1s1) 108270839(ap1s2) 108275964
PHYP: 113530822 113530955(ap1s2) 113539937(ap1s1)
SMEO: 124387920(ap1s1) 124390876(ap1s2) 124399061
TFD: 113641870 113657499(ap1s1) 113657877(ap1s2)
ELY: 117253742 117254401 117271381(ap1s3b) 117272719(ap1s1)
SLUC: 116035963(ap1s1) 116037222(ap1s3b) 116054588(ap1s2) 116058704
ECRA: 117934859(ap1s1) 117944349(ap1s2) 117950109 117953681(ap1s3b)
GAT: 120811534(ap1s2) 120815769(ap1s3b) 120822268(ap1s1) 120823678
PPUG: 119209080(ap1s3b) 119216225 119222439(ap1s1) 119226234(ap1s2)
CUD: 121504548(ap1s1) 121507575 121512177 121520771(ap1s3b)
OAU: 116311673 116324064(ap1s1) 116331294 116332869(ap1s3b)
OML: 112147083(ap1s3b) 112150169 112156409(ap1s1) 112160589(ap1s2)
PFOR: 103137158 103143570(ap1s2) 103148860 103148963(ap1s1)
PLAI: 106942561 106952019(ap1s2) 106956042(ap1s1) 106962205
PMEI: 106914646(ap1s2) 106921341 106924431(ap1s1) 106931453
GAF: 122820460(ap1s1) 122823068(ap1s2) 122838451 122841314(ap1s3b)
CTUL: 119777076 119778757(ap1s3b) 119782316(ap1s2) 119785460(ap1s1)
GMU: 124867041(ap1s2) 124869789(ap1s3b) 124873907 124881268(ap1s1)
KMR: 108240201 108242253(ap1s1) 108245521(ap1s3b) 108250539
ALIM: 106512429(ap1s2) 106526973(ap1s1) 106528171 106532077
NWH: 119414576(ap1s3b) 119429175(ap1s2) 119429897
HHIP: 117757991 117759716 117778514(ap1s3b) 117779323(ap1s1)
PKI: 111838252(ap1s2) 111852923
AANG: 118213766 118223281(ap1s1) 118223833(ap1s2) 118236257
LOC: 102684980(ap1s1) 102693378(ap1s2)
LCM: 102360227(AP1S2) 102360447(AP1S1)
CMK: 103177486(ap1s2) 103190658(ap1s1)
BFO: 118427838
BBEL: 109466962
CIN: 100179571
SCLV: 120326187
APLC: 110980978
SKO: 102807777
DME: Dmel_CG5864(AP-1sigma)
DER: 6555077
DSE: 6607655
DSI: Dsimw501_GD21048(Dsim_GD21048)
DAN: 6499816
DSR: 110191183
DPE: 6587336
DMN: 108156952
DWI: 6647642
DGR: 6567971
DAZ: 108612939
DNV: 108654001
DHE: 111602705
DVI: 6630768
CCAT: 101461466
BOD: 106616189
MDE: 101893587
SCAC: 106086736
LCQ: 111680933
ACOZ: 120947936
AARA: 120908407
AAG: 5567835
CPII: 120427252
CNS: 116344024
AME: 724303
ACER: 107995672
ALAB: 122719839
BIM: 100749537
BBIF: 117204067
BVK: 117231712
BVAN: 117155864
BTER: 100652035
BPYO: 122567134
CCAL: 108631867
OBB: 114880198
MGEN: 117219904
NMEA: 116434032
CGIG: 122397087
SOC: 105203644
MPHA: 105840646
AEC: 105144351
ACEP: 105627712
PBAR: 105434194
VEM: 105559550
HST: 105181608
DQU: 106746286
CFO: 105250927
FEX: 115243341
LHU: 105679984
PGC: 109853640
OBO: 105274729
PCF: 106784275
PFUC: 122521317
VPS: 122638212
NVI: 100113912
CSOL: 105367523
TPRE: 106648704
MDL: 103573247
CGLO: 123270985
FAS: 105269585
DAM: 107040234
AGIF: 122854851
CCIN: 107265255
TCA: 659702
DPA: 109532880
SOY: 115886857
CSET: 123315200
AGB: 108905662
LDC: 111507120
NVL: 108558061
APLN: 108741231
PPYR: 116181676
OTU: 111421212
BMOR: 692921(AP1S)
BMAN: 114239890
MSEX: 115447558
BANY: 112053203
PMAC: 106712912
PPOT: 106102737
PXU: 106117838
PRAP: 110999510
ZCE: 119838507
HAW: 110380047
TNL: 113493427
SLIU: 111356123
OFU: 114362147
PXY: 105384076
API: 100166710
DNX: 107173856
AGS: 114131000
RMD: 113549115
BTAB: 109032261
DCI: 103515127
CLEC: 106668448
HHAL: 106685685
NLU: 111054386
FOC: 113214807
ZNE: 110834006
CSEC: 111867438
FCD: 110844422
DMK: 116920112
PVM: 113814551
PCHN: 125042266
HAME: 121863294
PCLA: 123759409
PTRU: 123519979
HAZT: 108676474
DSV: 119441704
RSAN: 119386865
RMP: 119178692
VDE: 111249859
DPTE: 113792143
DFR: 124491574
CSCU: 111633368
SDM: 118180642
CEL: CELE_F29G9.3(aps-1)
CBR: CBG_09266(Cbr-aps-1)
BMY: BM_BM13787(Bma-aps-1)
PCAN: 112555297
BGT: 106065610
HRF: 124120884
HRJ: 124275444
CRG: 105344281
MYI: 110459990
PMAX: 117342955
OBI: 106883384
OSN: 115214086
LAK: 106160166
EGL: EGR_05627
NVE: 5517290
EPA: 110242026
ATEN: 116293371
ADF: 107336144
AMIL: 114954175
PDAM: 113676193
SPIS: 111330486
DGT: 114535657
XEN: 124447281
AQU: 100637868
ATH: AT2G17380(AP19) AT4G35410
CIT: 102626824
LJA: Lj0g3v0346919.1(Lj0g3v0346919.1) Lj0g3v0346919.2(Lj0g3v0346919.2) Lj0g3v0346929.1(Lj0g3v0346929.1) Lj2g3v2985930.1(Lj2g3v2985930.1)
ZJU: 107419435
MNT: 21396925
CSV: 101217518
CMO: 103500483
BHJ: 120078114
MCHA: 111007622
SLY: 101260000
SPEN: 107003002
SOT: 102603184
CANN: 107851269
NSY: 104246852
NTO: 104090274
NAU: 109207386
INI: 109182374
ITR: 116007681
EGT: 105959449
BVG: 104904104
NNU: 104608608
DOSA: Os03t0783700-00(Os03g0783700) Os03t0811300-01(Os03g0811300)
BDI: 100833430
ATS: 109759144
DCT: 110102771
PEQ: 110039361
MNG: MNEG_0285
APRO: F751_2161
SCE: YLR170C(APS1)
SEUB: DI49_3688
ERC: Ecym_2724
KMX: KLMA_40289(APS1)
NCS: NCAS_0A08790(NCAS0A08790)
NDI: NDAI_0G05210(NDAI0G05210)
TPF: TPHA_0B03570(TPHA0B03570)
TBL: TBLA_0A01260(TBLA0A01260)
TDL: TDEL_0B06190(TDEL0B06190)
KAF: KAFR_0I02080(KAFR0I02080)
KNG: KNAG_0I01390(KNAG0I01390)
CAL: CAALFM_CR05310WA(CaO19.1012)
NCR: NCU10618
NTE: NEUTE1DRAFT98501(NEUTE1DRAFT_98501)
MGR: MGG_11227
SSCK: SPSK_07865
MAJ: MAA_05639
CMT: CCM_08132
BFU: BCIN_14g01930(Bcaps1)
MBE: MBM_00494
ANI: AN7682.2
ANG: ANI_1_604034(An03g04910)
ALUC: AKAW2_50860S(VAS2)
CIM: CIMG_10479(CIMG00132)
ABE: ARB_05741
TVE: TRV_04501
PTE: PTT_13476
CNE: CNE04240
CNB: CNBE4230
TASA: A1Q1_06644
MORE: E1B28_001782 E1B28_006491(VAS2_1)
ABP: AGABI1DRAFT113333(AGABI1DRAFT_113333) AGABI1DRAFT66564(AGABI1DRAFT_66564)
ABV: AGABI2DRAFT192023(AGABI2DRAFT_192023) AGABI2DRAFT197752(AGABI2DRAFT_197752)
MGL: MGL_0669
MRT: MRET_2541
DDI: DDB_G0279359(ap1s1) DDB_G0295711(ap1s2)
DFA: DFA_03576 DFA_09635(ap1s2)
EHI: EHI_178740(15.t00050)
PCB: PCHAS_091430(PC001327.02.0)
TAN: TA06850
TPV: TP01_0754
BBO: BBOV_IV010890(23.m06432)
CPV: cgd8_4040
PTI: PHATRDRAFT_36149(AP1sigma)
SPAR: SPRG_09014
EHX: EMIHUDRAFT_438661(Aps1-1) EMIHUDRAFT_78860(Aps1-2)
GTT: GUITHDRAFT_163623(AP1S)
 » show all
Reference
PMID:9733768
  Authors
Takatsu H, Sakurai M, Shin HW, Murakami K, Nakayama K
  Title
Identification and characterization of novel clathrin adaptor-related proteins.
  Journal
J Biol Chem 273:24693-700 (1998)
DOI:10.1074/jbc.273.38.24693
  Sequence
[hsa:1174]

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