KEGG   ORTHOLOGY: K12395
Entry
K12395                      KO                                     
Symbol
AP1S3
Name
AP-1 complex subunit sigma-3
Pathway
map04142  Lysosome
map05170  Human immunodeficiency virus 1 infection
Disease
H01656  Psoriasis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    K12395  AP1S3; AP-1 complex subunit sigma-3
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K12395  AP1S3; AP-1 complex subunit sigma-3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12395  AP1S3; AP-1 complex subunit sigma-3
Membrane trafficking [BR:ko04131]
 Endosome - Golgi transport
  Others
   AP-1 complex
    K12395  AP1S3; AP-1 complex subunit sigma-3
Genes
HSA: 130340(AP1S3)
PTR: 459979(AP1S3)
PPS: 100981090(AP1S3)
GGO: 101130940(AP1S3)
PON: 100435961(AP1S3)
NLE: 100602846(AP1S3)
MCC: 710257(AP1S3)
MCF: 102141447(AP1S3)
CSAB: 103217955(AP1S3)
CATY: 105586990(AP1S3)
PANU: 101022509(AP1S3)
TGE: 112636250(AP1S3)
RRO: 104656437(AP1S3)
RBB: 108514204(AP1S3)
TFN: 117094457(AP1S3)
PTEH: 111549146(AP1S3)
CJC: 100385953(AP1S3)
SBQ: 101039675(AP1S3)
CSYR: 103269673(AP1S3)
MMUR: 105869355(AP1S3)
OGA: 100965909(AP1S3)
MMU: 252903(Ap1s3)
MCAL: 110303493(Ap1s3)
MPAH: 110322425(Ap1s3)
RNO: 367304(Ap1s3)
MCOC: 116088633(Ap1s3)
MUN: 110552879(Ap1s3)
CGE: 100764202(Ap1s3)
PLEU: 114703309(Ap1s3)
NGI: 103727779(Ap1s3)
HGL: 101698822(Ap1s3)
CPOC: 100718917(Ap1s3)
CCAN: 109696371(Ap1s3)
DORD: 105981011(Ap1s3)
DSP: 122107493(Ap1s3)
NCAR: 124978853
OCU: 100355197(AP1S3)
OPI: 101527765(AP1S3)
TUP: 102497153(AP1S3)
VVP: 112922437(AP1S3)
VLG: 121480658(AP1S3)
AML: 100464154(AP1S3)
UMR: 103662863(AP1S3)
UAH: 113250398(AP1S3)
UAR: 123778098(AP1S3)
ELK: 111139355
LLV: 125095125
MPUF: 101672273(AP1S3)
ORO: 101363248(AP1S3)
EJU: 114210752(AP1S3)
ZCA: 113919863(AP1S3)
MLX: 118012635(AP1S3)
FCA: 101084726(AP1S3)
PYU: 121014499(AP1S3)
PBG: 122481837(AP1S3)
PTG: 102961683(AP1S3)
PPAD: 109264988(AP1S3)
AJU: 106988181(AP1S3)
HHV: 120234833(AP1S3)
BTA: 540693(AP1S3)
BOM: 102271061(AP1S3)
BIU: 109575840(AP1S3)
BBUB: 102395799(AP1S3)
CHX: 102184293(AP1S3)
OAS: 101117145(AP1S3)
ODA: 120854462(AP1S3)
CCAD: 122426668(AP1S3)
SSC: 100627432(AP1S3)
CFR: 102514737(AP1S3)
CBAI: 105064104(AP1S3)
CDK: 105088305(AP1S3)
VPC: 102543064(AP1S3)
BACU: 102997819(AP1S3)
LVE: 103085995(AP1S3)
OOR: 101274379(AP1S3)
DLE: 111171873(AP1S3)
PCAD: 102995269(AP1S3)
PSIU: 116757092(AP1S3)
ECB: 100061230(AP1S3)
EPZ: 103550310(AP1S3)
EAI: 106832468(AP1S3)
MYB: 102244596(AP1S3)
MYD: 102762911(AP1S3)
MMYO: 118661350(AP1S3)
MLF: 102440123(AP1S3)
MNA: 107526690(AP1S3)
PKL: 118709332(AP1S3)
HAI: 109396185(AP1S3)
DRO: 112308043(AP1S3)
SHON: 118975437(AP1S3)
AJM: 119044727(AP1S3)
PDIC: 114495239(AP1S3)
PHAS: 123830020(AP1S3)
MMF: 118625841(AP1S3)
RFQ: 117026365(AP1S3)
PALE: 102893225(AP1S3)
PGIG: 120596823(AP1S3)
PVP: 105294756(AP1S3)
RAY: 107499072(AP1S3)
MJV: 108384297(AP1S3)
TOD: 119256256(AP1S3)
SARA: 101556655(AP1S3)
LAV: 100655898(AP1S3)
TMU: 101357881
DNM: 101424265(AP1S3)
MDO: 100022527(AP1S3)
GAS: 123242754(AP1S3) 123249021
SHR: 100922303(AP1S3)
PCW: 110219498(AP1S3)
OAA: 100081614(AP1S3)
GGA: 424807(AP1S3)
PCOC: 116230925(AP1S3)
MGP: 100551012(AP1S3)
CJO: 107318016(AP1S3)
NMEL: 110397459(AP1S3)
APLA: 101795480(AP1S3)
ACYG: 106036213(AP1S3)
AFUL: 116492379(AP1S3)
TGU: 100221442(AP1S3)
LSR: 110483643(AP1S3)
SCAN: 103815443(AP1S3)
PMOA: 120508557(AP1S3)
OTC: 121341145(AP1S3)
PRUF: 121357921(AP1S3)
GFR: 102043745(AP1S3)
FAB: 101817090(AP1S3)
PHI: 102104225(AP1S3)
PMAJ: 107209010(AP1S3)
CCAE: 111933555(AP1S3)
CCW: 104693419(AP1S3)
ETL: 114069333(AP1S3)
ZAB: 102064074(AP1S3)
FPG: 101914561(AP1S3)
FCH: 102052723(AP1S3)
CLV: 102091833(AP1S3)
EGZ: 104135440(AP1S3)
NNI: 104013000(AP1S3)
ACUN: 113483563(AP1S3)
TALA: 104365781(AP1S3)
PADL: 103917853(AP1S3)
ACHC: 115346903(AP1S3)
AAM: 106485846(AP1S3)
NPD: 112947912(AP1S3)
DNE: 112988836(AP1S3)
ASN: 102376352(AP1S3)
AMJ: 102566806(AP1S3)
CPOO: 109308637(AP1S3)
GGN: 109288196(AP1S3)
PSS: 102460224(AP1S3)
CMY: 102929315(AP1S3)
CPIC: 101949522(AP1S3)
TST: 117883151(AP1S3)
MRV: 120371330(AP1S3)
ACS: 100565890(ap1s3)
PVT: 110079965(AP1S3)
SUND: 121926555(AP1S3)
PBI: 103060144(AP1S3)
PMUR: 107290158(AP1S3)
TSR: 106543871(AP1S3)
PGUT: 117678375(AP1S3)
PMUA: 114597797(AP1S3)
ZVI: 118093885(AP1S3)
GJA: 107115865(AP1S3)
XLA: 108717084 443609(ap1s3.S)
XTR: 549333(ap1s3)
NPR: 108792662(AP1S3)
RTEM: 120936570(AP1S3)
BBUF: 120997734(AP1S3)
BGAR: 122935024(AP1S3)
DRE: 447897(ap1s3b) 550415(ap1s3a)
PPRM: 120470685 120470791(ap1s3a) 120471479(ap1s3b)
IPU: 108280899(ap1s3b)
PHYP: 113533140
SMEO: 124403104(ap1s3b)
TFD: 113640673(ap1s3b)
AMEX: 103023733
EEE: 113567836 113587007(ap1s3)
TRU: 101070445(ap1s3)
LCO: 104934358(ap1s3)
CGOB: 115018121
ELY: 117260300(ap1s3a)
PLEP: 121943051(ap1s3a)
SLUC: 116039020(ap1s3a)
ECRA: 117939901(ap1s3a)
PFLV: 114552796(ap1s3)
GAT: 120816589(ap1s3a)
PPUG: 119214413(ap1s3a)
MSAM: 119882720(ap1s3a)
CUD: 121523434(ap1s3a)
ONL: 100701959(ap1s3)
OAU: 116328121(ap1s3a)
OLA: 101157633(ap1s3)
OML: 112149887(ap1s3a)
XMA: 102221131(ap1s3)
XCO: 114133470(ap1s3)
XHE: 116737206(ap1s3)
PRET: 103474925(ap1s3)
PFOR: 103145231(ap1s3)
PLAI: 106953857(ap1s3)
PMEI: 106920626(ap1s3)
GAF: 122832638(ap1s3a)
CVG: 107103794
CTUL: 119775229(ap1s3a)
GMU: 124884515(ap1s3a)
NFU: 107380787(ap1s3)
KMR: 108249463(ap1s3a)
NWH: 119411503(ap1s3a)
AOCE: 111577114(ap1s3)
CSEM: 103377821(ap1s3)
POV: 109634538(ap1s3)
SSEN: 122760910(ap1s3a)
HHIP: 117772718(ap1s3a)
LCF: 108888202(ap1s3)
SDU: 111232824(ap1s3)
SLAL: 111671313(ap1s3)
XGL: 120791531(ap1s3a)
HCQ: 109510935(ap1s3)
BPEC: 110154579(ap1s3)
MALB: 109951317(ap1s3)
OTW: 112267251
OMY: 110503382
ELS: 105017110(ap1s3)
SFM: 108932483(ap1s3)
AANG: 118209861(ap1s3a) 118229606
LOC: 102685346(ap1s3)
PSPA: 121326476
LCM: 102367110(AP1S3)
CMK: 103175336
RTP: 109928774
 » show all
Reference
  Authors
Setta-Kaffetzi N, Simpson MA, Navarini AA, Patel VM, Lu HC, Allen MH, Duckworth M, Bachelez H, Burden AD, Choon SE, Griffiths CE, Kirby B, Kolios A, Seyger MM, Prins C, Smahi A, Trembath RC, Fraternali F, Smith CH, Barker JN, Capon F
  Title
AP1S3 mutations are associated with pustular psoriasis and impaired Toll-like receptor 3 trafficking.
  Journal
Am J Hum Genet 94:790-7 (2014)
DOI:10.1016/j.ajhg.2014.04.005
  Sequence
[hsa:130340]
Reference
  Authors
Boehm M, Bonifacino JS
  Title
Adaptins: the final recount.
  Journal
Mol Biol Cell 12:2907-20 (2001)
DOI:10.1091/mbc.12.10.2907
  Sequence
[hsa:130340]

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