KEGG   ORTHOLOGY: K12490
Entry
K12490                      KO                                     
Symbol
ARAP3
Name
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Pathway
map04015  Rap1 signaling pathway
map04024  cAMP signaling pathway
map04144  Endocytosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
   04024 cAMP signaling pathway
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Membrane trafficking [BR:ko04131]
 Endocytosis
  Arf GTPases and associated proteins
   Arf associated proteins
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
 Others
  Rho GTPase associated proteins
   Rho GTPase-activating proteins
    K12490  ARAP3; Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
Genes
HSA: 64411(ARAP3)
PTR: 462149(ARAP3)
PPS: 100977768(ARAP3)
GGO: 101137714(ARAP3)
PON: 100437871(ARAP3)
NLE: 100598122(ARAP3)
HMH: 116471641(ARAP3)
MCC: 701400(ARAP3)
MCF: 102124624(ARAP3)
MTHB: 126957237
MNI: 105466976(ARAP3)
CSAB: 103244701(ARAP3)
CATY: 105599935(ARAP3)
PANU: 101001754(ARAP3)
TGE: 112626943(ARAP3)
MLEU: 105534851(ARAP3)
RRO: 104681826(ARAP3)
RBB: 108530209(ARAP3)
TFN: 117065697(ARAP3)
PTEH: 111526958(ARAP3)
CANG: 105510111(ARAP3)
CJC: 100387074(ARAP3)
SBQ: 101037093(ARAP3)
CIMI: 108307079(ARAP3)
CSYR: 103269885(ARAP3)
MMUR: 105862632(ARAP3)
LCAT: 123637906(ARAP3)
PCOQ: 105811557(ARAP3)
OGA: 100942649(ARAP3)
MMU: 106952(Arap3)
MCAL: 110284610(Arap3)
MPAH: 110333208(Arap3)
RNO: 361314(Arap3)
MCOC: 116087072(Arap3)
ANU: 117719827(Arap3)
MUN: 110557094(Arap3)
CGE: 100752046(Arap3)
MAUA: 101826958(Arap3)
PROB: 127234030(Arap3)
MORG: 121453343(Arap3)
MFOT: 126491950
AAMP: 119814639(Arap3)
NGI: 103736075(Arap3)
HGL: 101709044(Arap3)
CPOC: 100721743(Arap3)
CCAN: 109681337(Arap3)
DORD: 105988745(Arap3)
DSP: 122118187(Arap3)
PLOP: 125339770(Arap3)
NCAR: 124986802
MMMA: 107142144(Arap3)
OCU: 100354264
OPI: 101529450(ARAP3)
TUP: 102470245(ARAP3)
GVR: 103587910(ARAP3)
CFA: 487188(ARAP3)
CLUD: 112658888(ARAP3)
VVP: 112934640(ARAP3)
VLG: 121497329(ARAP3)
NPO: 129514011(ARAP3)
AML: 100465375(ARAP3)
UMR: 103663721(ARAP3)
UAH: 113255371(ARAP3)
UAR: 123790219(ARAP3)
ELK: 111156922
LLV: 125099676
MPUF: 101673908(ARAP3)
MNP: 132028608(ARAP3)
MLK: 131832183(ARAP3)
NVS: 122890013(ARAP3)
ORO: 101366666(ARAP3)
EJU: 114200662(ARAP3)
ZCA: 113929433(ARAP3)
MLX: 118016745(ARAP3)
NSU: 110590929(ARAP3)
LWW: 102726470(ARAP3)
FCA: 101080259(ARAP3)
PYU: 121016641(ARAP3)
PCOO: 112861091(ARAP3)
PBG: 122483746(ARAP3)
PVIV: 125169827(ARAP3)
LRUF: 124516904
PTG: 102962215(ARAP3)
PPAD: 109252207(ARAP3)
PUC: 125934878
AJU: 106968226
HHV: 120234355(ARAP3)
BTA: 112447442(ARAP3)
BOM: 102265022(ARAP3)
BIU: 109561086(ARAP3)
BBUB: 102411515(ARAP3)
BBIS: 104996240(ARAP3)
CHX: 102184425(ARAP3)
OAS: 101105821(ARAP3)
BTAX: 128050452(ARAP3)
ODA: 120863533(ARAP3)
CCAD: 122439781(ARAP3)
MBEZ: 129558724(ARAP3)
SSC: 100511744(ARAP3)
CFR: 102511883(ARAP3)
CBAI: 105065468(ARAP3)
CDK: 105090802(ARAP3)
VPC: 102538920(ARAP3)
BACU: 103013330(ARAP3)
BMUS: 118892095(ARAP3)
LVE: 103082900(ARAP3)
OOR: 101280167(ARAP3)
DLE: 111183025(ARAP3)
PCAD: 102979637(ARAP3)
PSIU: 116751544(ARAP3)
NASI: 112404367(ARAP3)
ECB: 100072169(ARAP3)
EPZ: 103550695(ARAP3)
EAI: 106836965(ARAP3)
MYB: 102253252(ARAP3)
MYD: 102761561(ARAP3)
MMYO: 118658849(ARAP3)
MLF: 102436129(ARAP3)
PKL: 118711329(ARAP3)
EFUS: 103285630(ARAP3)
MNA: 107531508(ARAP3)
DRO: 112318118(ARAP3)
SHON: 118998505(ARAP3)
AJM: 119051057(ARAP3)
PDIC: 114509280(ARAP3)
PHAS: 123809987(ARAP3)
MMF: 118615668(ARAP3)
PPAM: 129066592(ARAP3)
HAI: 109393984(ARAP3)
RFQ: 117016949(ARAP3)
PALE: 102897313(ARAP3)
PGIG: 120581446(ARAP3)
PVP: 105297072(ARAP3) 105311236
RAY: 107499695(ARAP3)
MJV: 108405531(ARAP3)
TOD: 119243341(ARAP3)
SARA: 101549734(ARAP3)
SETR: 126027948(ARAP3)
LAV: 100657212(ARAP3)
TMU: 101357139
ETF: 101663025(ARAP3)
DNM: 101415638(ARAP3)
MDO: 100027875(ARAP3)
GAS: 123233833
SHR: 100928929(ARAP3)
AFZ: 127550035
PCW: 110220838(ARAP3)
OAA: 100076932(ARAP3)
GGA: 416196(ARAP3)
PCOC: 116231947(ARAP3)
MGP: 100543789(ARAP3)
CJO: 107320281(ARAP3)
TPAI: 128081393(ARAP3)
LMUT: 125700393(ARAP3)
NMEL: 110405328(ARAP3)
APLA: 101796955(ARAP3)
ACYG: 106034417(ARAP3)
CATA: 118256156(ARAP3)
AFUL: 116494656(ARAP3)
TGU: 100220646(ARAP3)
LSR: 110480255(ARAP3)
SCAN: 103817415(ARAP3)
PMOA: 120499186(ARAP3)
OTC: 121343327(ARAP3)
PRUF: 121354864(ARAP3)
GFR: 102032084(ARAP3)
FAB: 101817352(ARAP3)
OMA: 130258533(ARAP3)
PHI: 102108475(ARAP3)
PMAJ: 107210565(ARAP3)
CCAE: 111935703(ARAP3)
CCW: 104696073(ARAP3)
CBRC: 103614992(ARAP3)
ETL: 114066132(ARAP3)
ZAB: 102067758(ARAP3)
ACHL: 103806636
SVG: 106861321(ARAP3)
MMEA: 130585195(ARAP3)
HRT: 120759061(ARAP3)
FPG: 101917849(ARAP3)
FCH: 102055065(ARAP3)
CLV: 102092535(ARAP3)
EGZ: 104135761(ARAP3)
NNI: 104016573(ARAP3)
PCRI: 104031640(ARAP3)
PLET: 104619604(ARAP3)
EHS: 104512713(ARAP3)
PCAO: 104041797(ARAP3)
ACUN: 113485333(ARAP3)
TALA: 104359539(ARAP3)
PADL: 103921971(ARAP3)
AFOR: 103898949(ARAP3)
ACHC: 115334403(ARAP3)
HALD: 104320814(ARAP3)
HLE: 104839061(ARAP3)
AGEN: 126051060
GCL: 127022149
CCRI: 104166641(ARAP3)
CSTI: 104563776
CMAC: 104481834(ARAP3)
MUI: 104543518(ARAP3)
BREG: 104633584(ARAP3)
FGA: 104083127
LDI: 104349859(ARAP3)
MNB: 103779940
OHA: 104338340(ARAP3)
NNT: 104404298(ARAP3)
SHAB: 115615672(ARAP3)
PGUU: 104472148(ARAP1)
ACAR: 104522777
CPEA: 104392049(ARAP3)
AVIT: 104273448(ARAP3)
CVF: 104282606(ARAP3)
RTD: 128916258(ARAP3)
CUCA: 104065871(ARAP3)
BRHI: 104493312
AAM: 106488076(ARAP3)
AROW: 112968423(ARAP3)
NPD: 112951741(ARAP3)
TGT: 104578922(ARAP3)
DNE: 112981820(ARAP3)
SCAM: 104154021(ARAP3)
ASN: 102385140(ARAP3)
AMJ: 102562874(ARAP3)
CPOO: 109309919(ARAP3)
GGN: 109290172(ARAP3)
CMY: 102941861(ARAP3)
CCAY: 125641232(ARAP3)
DCC: 119859944(ARAP3)
CPIC: 101946704(ARAP3)
TST: 117881555(ARAP3)
CABI: 116820887(ARAP3)
MRV: 120369968(ARAP3)
ACS: 100561635(arap3)
ASAO: 132774281(ARAP3)
PVT: 110082024(ARAP3)
SUND: 121929327(ARAP3)
PBI: 103057750(ARAP3)
PMUR: 107299164(ARAP3)
CTIG: 120300256(ARAP3)
TSR: 106547848
PTEX: 113448139(ARAP3)
NSS: 113422333(ARAP3)
VKO: 123029665(ARAP3)
PMUA: 114601098(ARAP3)
PRAF: 128418010(ARAP3)
ZVI: 118079319(ARAP3)
HCG: 128324980(ARAP3)
GJA: 107124863
STOW: 125443754(ARAP3)
EMC: 129333472(ARAP3)
XLA: 108710892 108713296
XTR: 100492779(arap3)
NPR: 108785748(ARAP3)
RTEM: 120932503(ARAP3)
BBUF: 121008498(ARAP3)
BGAR: 122923256(ARAP3)
MUO: 115475463(ARAP3)
GSH: 117351491(ARAP3)
DRE: 558931(arap3)
SRX: 107717393 107741086
SANH: 107662027 107664716
SGH: 107563596 107598344(arap3)
CCAR: 109069922
CAUA: 113057804 113058109 113114249
CGIB: 127971712 128027318
PTET: 122358079(arap3)
LROH: 127176504(arap3)
OMC: 131553631(arap3)
PPRM: 120460878(arap3)
RKG: 130084849(arap3)
MAMB: 125259047(arap3)
CIDE: 127494357
MASI: 127413015 127417986
TROS: 130564138(arap3)
TDW: 130438308(arap3)
MANU: 129422321(arap3)
IPU: 108269111
IFU: 128611448(arap3)
PHYP: 113528795(arap3)
SMEO: 124385924(arap3)
TFD: 113635801(arap3)
TVC: 132855752(arap3)
AMEX: 103033395
CMAO: 118806882(arap3)
EEE: 113573380
CHAR: 105911201(arap3)
TRU: 105418312 115248421
TFS: 130531504(arap3)
TNG: GSTEN00004670G001
LCO: 104936083(arap3)
TBEN: 117482579(arap3)
CGOB: 115005929(arap3)
GACU: 117535127(arap3)
EMAC: 134859956(arap3)
ELY: 117261179(arap3)
EFO: 125894784(arap3)
PLEP: 121947789
SLUC: 116051159(arap3)
PFLV: 114563000(arap3)
GAT: 120817803(arap3)
PPUG: 119211441(arap3)
AFB: 129089823(arap3)
CLUM: 117737217(arap3)
MSAM: 119888686(arap3)
SCHU: 122880433(arap3)
CUD: 121516165(arap3)
ALAT: 119007164(arap3)
MZE: 101467418(arap3)
ONL: 100711520(arap3)
OAU: 116335513(arap3)
OLA: 101162821(arap3)
OML: 112153181(arap3)
CSAI: 133446702 133447741
XMA: 102237474(arap3)
XCO: 114139599(arap3)
XHE: 116714578(arap3)
PRET: 103471782(arap3)
PFOR: 103155966(arap3)
PLAI: 106939943
PMEI: 106922903
GAF: 122836767(arap3)
PPRL: 129354319
CVG: 107082704(arap3)
CTUL: 119784579(arap3)
GMU: 124860745(arap3)
NFU: 107381061(arap3)
KMR: 108248976(arap3)
ALIM: 106533294
NWH: 119408820(arap3)
AOCE: 111586047(arap3)
MCEP: 125008055(arap3)
CSEM: 103390798(arap3)
POV: 109643191
SSEN: 122762757 122778749
HHIP: 117769181(arap3)
HSP: 118112323(arap3)
SMAU: 118319230(arap3)
LCF: 108891792
SDU: 111233521(arap3)
SLAL: 111665612(arap3)
XGL: 120785040(arap3)
HCQ: 109508299(arap3)
SSCV: 125981353
SBIA: 133508697(arap3)
PEE: 133407575(arap3)
PTAO: 133484557(arap3)
BPEC: 110168021
MALB: 109956747(arap3)
BSPL: 114864033(arap3)
SJO: 128362649(arap3)
SASA: 106594768 106604143 106612290
STRU: 115167133 115205733
OTW: 112239485(arap3) 112255862
OMY: 110487789 110504357(arap3)
OGO: 123993734(arap3) 124011592
ONE: 115121950 115124096
OKI: 109878030 109910211
OKE: 118373490 118378380
SALP: 111965591 111967067
SNH: 120047880(arap3) 120062170
CCLU: 121530728 121538634
ELS: 105007474(arap3)
SFM: 108922908(arap3)
PKI: 111836366(arap3)
AANG: 118223265(arap3)
LOC: 102692407(arap3)
PSPA: 121297017 121324109
ARUT: 117413330 117431623
PSEX: 120542267(arap3)
LCM: 102359686(ARAP3)
CMK: 103184169(arap3)
CPLA: 122559892(arap3)
HOC: 132823516(arap3)
LERI: 129701500(arap3)
TAD: TRIADDRAFT_59978
 » show all
Reference
PMID:15296756
  Authors
Krugmann S, Williams R, Stephens L, Hawkins PT
  Title
ARAP3 is a PI3K- and rap-regulated GAP for RhoA.
  Journal
Curr Biol 14:1380-4 (2004)
DOI:10.1016/j.cub.2004.07.058
Reference
PMID:11804589
  Authors
Krugmann S, Anderson KE, Ridley SH, Risso N, McGregor A, Coadwell J, Davidson K, Eguinoa A, Ellson CD, Lipp P, Manifava M, Ktistakis N, Painter G, Thuring JW, Cooper MA, Lim ZY, Holmes AB, Dove SK, Michell RH, Grewal A, Nazarian A, Erdjument-Bromage H, Tempst P, Stephens LR, Hawkins PT
  Title
Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices.
  Journal
Mol Cell 9:95-108 (2002)
DOI:10.1016/S1097-2765(02)00434-3
  Sequence
[hsa:64411]

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Gene (933)   
   KEGG GENES (401)   
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   RefGene (202)   
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