KEGG   ORTHOLOGY: K12619
Entry
K12619                      KO                                     

Name
XRN2, RAT1
Definition
5'-3' exoribonuclease 2 [EC:3.1.13.-]
Pathway
ko03008  Ribosome biogenesis in eukaryotes
ko03018  RNA degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   03008 Ribosome biogenesis in eukaryotes
    K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
  09123 Folding, sorting and degradation
   03018 RNA degradation
    K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery
    K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
   03019 Messenger RNA biogenesis
    K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
   03009 Ribosome biogenesis
    K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
   03016 Transfer RNA biogenesis
    K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.13  Exoribonucleases producing 5'-phosphomonoesters
    3.1.13.-  
     K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
Transcription machinery [BR:ko03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic type
  mRNA degradation factors
   5'-3' decay
    5' exonucleases
     K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
Ribosome biogenesis [BR:ko03009]
 Eukaryotic type
  Pre-60S particles
   RNases
    K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
Transfer RNA biogenesis [BR:ko03016]
 Eukaryotic type
  tRNA degradation factors
   Rapid tRNA decay (RTD) pathway factors
    K12619  XRN2, RAT1; 5'-3' exoribonuclease 2
Genes
HSA: 22803(XRN2)
PTR: 458131(XRN2)
PPS: 100981151(XRN2)
GGO: 101139932(XRN2)
PON: 100173960(XRN2)
NLE: 100593111(XRN2)
MCC: 700934(XRN2)
MCF: 102134671(XRN2)
CSAB: 103215286(XRN2)
RRO: 104666944(XRN2)
RBB: 108536432(XRN2)
CJC: 100388181(XRN2)
SBQ: 101047908(XRN2)
MMU: 24128(Xrn2)
MCAL: 110310241(Xrn2)
MPAH: 110318322(Xrn2)
RNO: 362229(Xrn2)
MUN: 110553976(Xrn2)
CGE: 100770311(Xrn2)
NGI: 103740603(Xrn2)
HGL: 101697198(Xrn2)
CCAN: 109699816(Xrn2)
OCU: 100353161(XRN2)
TUP: 102490729(XRN2)
CFA: 477133(XRN2)
VVP: 112922703(XRN2)
AML: 100468930(XRN2)
UMR: 103677852(XRN2)
UAH: 113246784(XRN2)
ORO: 101381649(XRN2)
ELK: 111141389
FCA: 101084699(XRN2)
PTG: 102950740(XRN2)
PPAD: 109274657(XRN2)
AJU: 106984730(XRN2)
BTA: 517417(XRN2)
BOM: 102273486(XRN2)
BIU: 109568047(XRN2)
BBUB: 102410632(XRN2)
CHX: 102171526(XRN2)
OAS: 101102410(XRN2)
SSC: 100517201(XRN2)
CFR: 102504615(XRN2)
CDK: 105101564(XRN2)
BACU: 103000607(XRN2)
LVE: 103072390(XRN2)
OOR: 101282901(XRN2)
DLE: 111185048(XRN2)
PCAD: 102981997(XRN2)
ECB: 100050094(XRN2)
EPZ: 103563461(XRN2)
EAI: 106840312(XRN2)
MYB: 102263305(XRN2)
MYD: 102759792(XRN2)
MNA: 107536325(XRN2)
HAI: 109373916(XRN2)
DRO: 112304193(XRN2)
PALE: 102893608(XRN2)
RAY: 107500776(XRN2)
LAV: 100654986(XRN2)
TMU: 101354926
MDO: 100031372(XRN2)
SHR: 100926971(XRN2)
PCW: 110208731(XRN2)
OAA: 100074900(XRN2)
GGA: 421236(XRN2)
CJO: 107310734(XRN2)
NMEL: 110395808(XRN2)
APLA: 101794687(XRN2)
ACYG: 106042287(XRN2)
TGU: 100225776(XRN2)
LSR: 110474346(XRN2)
SCAN: 103819264(XRN2)
GFR: 102043356(XRN2)
FAB: 101816872(XRN2)
PHI: 102108757(XRN2)
PMAJ: 107201361(XRN2)
CCAE: 111926373(XRN2)
CCW: 104691474(XRN2)
ETL: 114067804(XRN2)
FPG: 101919651(XRN2)
FCH: 102053601(XRN2)
CLV: 102093706(XRN2)
EGZ: 104133448(XRN2)
NNI: 104022453(XRN2)
ACUN: 113478504(XRN2)
PADL: 103922061(XRN2)
AAM: 106499579(XRN2)
ASN: 102374361(XRN2)
AMJ: 102558593(XRN2)
PSS: 102452295(XRN2)
CMY: 102941188(XRN2)
CPIC: 101947639(XRN2)
ACS: 100562943(xrn2)
PVT: 110077452(XRN2)
PBI: 103063230(XRN2)
PMUR: 107297762(XRN2)
TSR: 106552193(XRN2)
PMUA: 114601202(XRN2)
GJA: 107106120(XRN2)
XLA: 100049102(xrn2.L) 108716605
XTR: 733834(xrn2)
NPR: 108804761(XRN2)
DRE: 321940(xrn2)
SRX: 107719412 107745894(xrn2)
IPU: 108257946(xrn2)
PHYP: 113531933(xrn2)
AMEX: 103036099(xrn2)
EEE: 113571690(xrn2)
TRU: 101080068(xrn2)
LCO: 104939755(xrn2)
MZE: 101473736(xrn2)
ONL: 100696623(xrn2)
OLA: 101163131(xrn2)
XMA: 102222739(xrn2)
XCO: 114158956(xrn2)
PRET: 103457049(xrn2)
CVG: 107098172(xrn2)
NFU: 107378188(xrn2)
KMR: 108228906(xrn2)
ALIM: 106524235(xrn2)
AOCE: 111582655(xrn2)
CSEM: 103381319(xrn2)
LCF: 108872468(xrn2)
SDU: 111216427(xrn2)
SLAL: 111645237(xrn2)
HCQ: 109516769(xrn2)
MALB: 109971310(xrn2)
SASA: 106571262
OTW: 112250005
SALP: 111954157
ELS: 105017831(xrn2)
LCM: 102366306(XRN2)
CMK: 103181691(xrn2)
BFO: 118411812
CIN: 100177034
SPU: 590369
SKO: 100376752(XRN2)
DME: Dmel_CG10354(Rat1)
DER: 6542584
DSI: Dsimw501_GD23438(Dsim_GD23438)
DSR: 110185682
DPE: 113565487
DMN: 108161907
DHE: 111600864
MDE: 101894988
AAG: 5578992
AME: 408840
BIM: 100745013
BTER: 100644887
CCAL: 108627054
OBB: 114872943
SOC: 105205191
MPHA: 105833546
AEC: 105149991
ACEP: 105621236
PBAR: 105428363
VEM: 105569456
HST: 105184218
DQU: 106740771
CFO: 105249372
LHU: 105677838
PGC: 109857581
OBO: 105286335
PCF: 106790099
NVI: 100117393
TCA: 662556
BMOR: 101746473
BMAN: 114248413
PRAP: 111003936
TNL: 113504793
PXY: 105381915
API: 100159621
DNX: 107171441
AGS: 114128954
RMD: 113552326
FCD: 110844059
CEL: CELE_Y48B6A.3(xrn-2)
CBR: CBG20900(Cbr-xrn-2)
BMY: Bm1_49855
TSP: Tsp_08094
CRG: 105345357
OBI: 106869156
NVE: 116604541
EPA: 110245011
AMIL: 114975336
DGT: 114531593
HMG: 100205936
AQU: 100640875
ATH: AT1G75660(XRN3) AT5G42540(XRN2)
ALY: 9299844
RCN: 112169420
PPER: 18792164
PAVI: 110771075
MDM: 103450393
PXB: 103927935
QSU: 112002385
INI: 109170026
SIND: 105166022
DOSA: Os01t0872700-01(Os01g0872700)
OBR: 102710165
BDI: 100835512
ATS: 109748677
SBI: 8085812
ZMA: 103649964
SITA: 101753124
PDA: 103720841
EGU: 105035524
MUS: 103993606
DCT: 110098478
PEQ: 110038885
AOF: 109825184
OLU: OSTLU_526
SCE: YOR048C(RAT1)
ERC: Ecym_5486
KMX: KLMA_20373(RAT1)
NCS: NCAS_0G00590(NCAS0G00590)
NDI: NDAI_0F00680(NDAI0F00680)
TPF: TPHA_0J01240(TPHA0J01240)
TBL: TBLA_0A09480(TBLA0A09480)
TDL: TDEL_0B02780(TDEL0B02780)
KAF: KAFR_0C06110(KAFR0C06110)
CAL: CAALFM_C401080WA(RAT1)
SLB: AWJ20_5114(RAT1)
NCR: NCU01643
MGR: MGG_11426
SSCK: SPSK_01409
MAW: MAC_09299
MAJ: MAA_02697
CMT: CCM_07458
BFU: BCIN_13g04510(Bcrat1)
MBE: MBM_07364
ANI: AN0707.2
ANG: ANI_1_968074(An08g06790)
ABE: ARB_05228
TVE: TRV_02267
PTE: PTT_07622
SPO: SPAC26A3.12c(dhp1)
CNE: CNF01810
CNB: CNBF2890
MGL: MGL_2332
MRT: MRET_0181
EHI: EHI_080270(293.t00010) EHI_093360(22.t00005) EHI_128220 EHI_132400(297.t00006) EHI_133330(5.t00013)
TAN: TA08085
TPV: TP04_0369
BBO: BBOV_II002230(18.m06180)
CPV: cgd8_2250
 » show all
Reference
  Authors
Fang F, Phillips S, Butler JS
  Title
Rat1p and Rai1p function with the nuclear exosome in the processing and degradation of rRNA precursors.
  Journal
RNA 11:1571-8 (2005)
DOI:10.1261/rna.2900205
  Sequence
[sce:YOR048C]
Reference
  Authors
Kim M, Krogan NJ, Vasiljeva L, Rando OJ, Nedea E, Greenblatt JF, Buratowski S
  Title
The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.
  Journal
Nature 432:517-22 (2004)
DOI:10.1038/nature03041
  Sequence
[sce:YOR048C]

DBGET integrated database retrieval system