KEGG   ORTHOLOGY: K12806
Entry
K12806                      KO                                     
Symbol
CARD16_17_18
Name
caspase recruitment domain-containing protein 16/17/18
Pathway
map04621  NOD-like receptor signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K12806  CARD16_17_18; caspase recruitment domain-containing protein 16/17/18
Other DBs
GO: 0004869
Genes
HSA: 114769(CARD16) 59082(CARD18)
PTR: 451519 451520 735456
GGO: 101138158(CARD16) 101139631(CARD18) 101140577
PON: 100440132(CARD18) 103891899(CARD16) 112135531
MCC: 106993454(CARD16) 705678(CARD18) 706971
MCF: 102121933(CARD18)
CSAB: 103248364(CARD16)
CATY: 105588752(CARD18) 105588756 105588790
PANU: 101008343(CARD16) 103881450
TGE: 112633131(CARD18)
RBB: 108513169(CARD18) 108513178(CARD16) 108531418
TFN: 117080201(CARD18) 117080364
PTEH: 111532121(CARD18)
CJC: 100385976(CARD18)
SBQ: 101049025(CARD18)
CSYR: 110596261
OGA: 111721902
OPI: 105941816
LVE: 103079704
MMYO: 118664120(CARD18)
MLF: 102429744(CARD18)
MNA: 107532339
AJM: 119060749(CARD16)
PDIC: 118501218(CARD16)
PHAS: 123819738(CARD16)
MMF: 118627743(CARD18) 118627744(CARD16)
PALE: 102895388
RAY: 107504290
OAU: 116318252
OMY: 110499420
BFO: 118406098
 » show all
Reference
  Authors
Humke EW, Shriver SK, Starovasnik MA, Fairbrother WJ, Dixit VM
  Title
ICEBERG: a novel inhibitor of interleukin-1beta generation.
  Journal
Cell 103:99-111 (2000)
DOI:10.1016/S0092-8674(00)00108-2
  Sequence
[hsa:59082]
Reference
  Authors
Druilhe A, Srinivasula SM, Razmara M, Ahmad M, Alnemri ES
  Title
Regulation of IL-1beta generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins.
  Journal
Cell Death Differ 8:649-57 (2001)
DOI:10.1038/sj.cdd.4400881
  Sequence
[hsa:114769]
Reference
  Authors
Lamkanfi M, Denecker G, Kalai M, D'hondt K, Meeus A, Declercq W, Saelens X, Vandenabeele P
  Title
INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation.
  Journal
J Biol Chem 279:51729-38 (2004)
DOI:10.1074/jbc.M407891200

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