KEGG   ORTHOLOGY: K12901
Entry
K12901            Tight     KO                                     
Symbol
fomC
Name
phosphonoacetaldehyde reductase
Pathway
map00440  Phosphonate and phosphinate metabolism
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00903  Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
Reaction
R08861  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00440 Phosphonate and phosphinate metabolism
    K12901  fomC; phosphonoacetaldehyde reductase
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K12901  fomC; phosphonoacetaldehyde reductase
Genes
AG: BAA32497(fomC)
Reference
  Authors
Metcalf WW, van der Donk WA
  Title
Biosynthesis of phosphonic and phosphinic acid natural products.
  Journal
Annu Rev Biochem 78:65-94 (2009)
DOI:10.1146/annurev.biochem.78.091707.100215
Reference
  Authors
Woodyer RD, Shao Z, Thomas PM, Kelleher NL, Blodgett JA, Metcalf WW, van der Donk WA, Zhao H
  Title
Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster.
  Journal
Chem Biol 13:1171-82 (2006)
DOI:10.1016/j.chembiol.2006.09.007

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