KEGG ORTHOLOGY: K12958

ORTHOLOGY: K12958

Entry

K12958                      KO

Symbol

CAV2

Name

caveolin 2

Pathway

map04144

Endocytosis

map04510

Focal adhesion

map05020

Prion disease

map05100

Bacterial invasion of epithelial cells

map05205

Proteoglycans in cancer

map05418

Fluid shear stress and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K12958  CAV2; caveolin 2
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K12958  CAV2; caveolin 2
09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    K12958  CAV2; caveolin 2
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    K12958  CAV2; caveolin 2
  09164 Neurodegenerative disease
   05020 Prion disease
    K12958  CAV2; caveolin 2
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K12958  CAV2; caveolin 2
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K12958  CAV2; caveolin 2
Membrane trafficking [BR:ko04131]
Endocytosis
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    K12958  CAV2; caveolin 2

Genes

HSA:

858(CAV2)

PTR:	736452(CAV2)

PPS:	100992816(CAV2)

GGO:	101124237(CAV2)

PON:	100137028(CAV2)

NLE:	100596151(CAV2)

HMH:	116814269(CAV2)

MCC:	706980(CAV2)

MCF:	102122005(CAV2)

MTHB:

126951208

MNI:	105475647(CAV2)

CSAB:

103226769(CAV2)

CATY:

105598472(CAV2)

PANU:

100126667(CAV2)

TGE:	112621101(CAV2)

RRO:	104682637(CAV2)

RBB:	108528701(CAV2)

TFN:	117073440(CAV2)

PTEH:

111553423(CAV2)

CJC:	100414174(CAV2)

SBQ:	101039961(CAV2)

CIMI:

108308981(CAV2)

MMUR:

105869365(CAV2)

LCAT:

123647403(CAV2)

PCOQ:

105817145(CAV2)

OGA:	100961631(CAV2)

MMU:	12390(Cav2)

MCAL:

110296653(Cav2)

MPAH:

110315911(Cav2)

RNO:	363425(Cav2)

MCOC:

116098598(Cav2)

ANU:	117720388(Cav2)

MUN:	110552609(Cav2)

CGE:	100751645(Cav2)

MAUA:

106020726(Cav2)

PROB:

127215334(Cav2)

PLEU:

114694723(Cav2)

MORG:

121463515(Cav2)

MFOT:

126503970

AAMP:

119807487(Cav2)

NGI:	103737451(Cav2)

HGL:	101696479(Cav2)

CPOC:

106028787(Cav2)

CCAN:

109689881(Cav2)

DORD:

105988350(Cav2)

DSP:	122121810(Cav2)

PLOP:

125347054(Cav2)

NCAR:

124990334

MMMA:

107144487(Cav2)

OCU:	100126563(CAV2)

OPI:	101518247(CAV2)

TUP:	102486965(CAV2)

GVR:	103597231(CAV2)

CFA:	475294(CAV2)

CLUD:

112670794(CAV2)

VVP:	112929900(CAV2)

VLG:	121474665(CAV2)

NPO:	129502967(CAV2)

AML:	100481243(CAV2)

UMR:	103676671(CAV2)

UAH:	113263196(CAV2)

UAR:	123789036(CAV2)

ELK:

111151976

LLV:

125080942

MPUF:

101676645(CAV2)

MNP:	132015772(CAV2)

MLK:	131829657(CAV2)

NVS:	122905005(CAV2)

ORO:	101366509(CAV2)

EJU:	114210654(CAV2)

ZCA:	113911890(CAV2)

MLX:	118021007(CAV2)

NSU:	110588903(CAV2)

LWW:	102734825(CAV2)

FCA:	493667(CAV2)

PYU:	121028449(CAV2)

PCOO:

112867055(CAV2)

PBG:	122488131(CAV2)

PVIV:

125160280(CAV2)

LRUF:

124524324

PTG:	102952837(CAV2)

PPAD:

109248392(CAV2)

PUC:

125930882

AJU:

106970672

HHV:	120223825(CAV2)

BTA:	493642(CAV2)

BOM:	102284893(CAV2)

BIU:	109557415(CAV2)

BBIS:

104981939(CAV2)

CHX:	102176581(CAV2)

OAS:	100126571(CAV2)

BTAX:

128046728(CAV2)

ODA:	120878213(CAV2)

CCAD:

122438346(CAV2)

MBEZ:

129552428(CAV2)

SSC:	100125375(CAV2)

CFR:	102524490(CAV2)

CBAI:

105063151(CAV2)

CDK:	105085318(CAV2)

VPC:	102537479(CAV2)

BACU:

103001094(CAV2)

BMUS:

118900506(CAV2)

LVE:	103068687(CAV2)

OOR:	101280988(CAV2)

DLE:	111179321(CAV2)

PCAD:

102977968(CAV2)

PSIU:

116759350(CAV2)

NASI:

112408234(CAV2)

ECB:	100071136(CAV2)

EPZ:	103561371(CAV2)

EAI:	106829266(CAV2)

MYB:	102264168(CAV2)

MYD:	102756981(CAV2)

MMYO:

118666483(CAV2)

MLF:	102418076(CAV2)

PKL:	118711656(CAV2)

EFUS:

103295927(CAV2)

MNA:	107528527(CAV2)

DRO:	112300182(CAV2)

AJM:	119052720(CAV2)

PDIC:

114507681(CAV2)

PHAS:

123824737(CAV2)

MMF:	118619898(CAV2)

PPAM:

129062965(CAV2)

HAI:	109389345(CAV2)

RFQ:	117018072(CAV2)

PALE:

102887161(CAV2)

PGIG:

120601227(CAV2)

PVP:	105300273(CAV2)

RAY:	107497469(CAV2)

MJV:	108399324(CAV2) 118973391

TOD:	119245943(CAV2)

SARA:

101557315(CAV2)

SETR:

126005036(CAV2)

LAV:	100655716(CAV2)

TMU:

101347312

ETF:	101655557(CAV2)

DNM:	101435788(CAV2)

MDO:	100011724(CAV2)

GAS:	123250726(CAV2)

SHR:	100916483(CAV2)

AFZ:

127564303

PCW:	110202942(CAV2)

OAA:	100091379 114814756(CAV2)

GGA:	417772(CAV2)

PCOC:

116243996(CAV2)

MGP:	104909643(CAV2)

CJO:	107309156(CAV2)

TPAI:

128073484(CAV2)

LMUT:

125694145(CAV2)

NMEL:

110392606(CAV2)

APLA:

101805307(CAV2)

ACYG:

106042050(CAV2)

CATA:

118246894(CAV2)

AFUL:

116500629(CAV2)

TGU:	101234223(CAV2)

LSR:	110477138(CAV2)

SCAN:

103813681(CAV2)

OTC:	121344793(CAV2)

PRUF:

121355783(CAV2)

GFR:	102040661(CAV2)

FAB:	101810092(CAV2)

OMA:	130261598(CAV2)

PHI:	102100230(CAV2)

PMAJ:

107205109(CAV2)

CCAE:

111922633(CAV2)

CCW:	104698291(CAV2)

CBRC:

103614856(CAV2)

ETL:	114062359(CAV2)

ZAB:	102070512(CAV2)

ACHL:

103811674(CAV2)

SVG:	106863115(CAV2)

MMEA:

130589232(CAV2)

HRT:	120752225(CAV2)

FPG:	101912583(CAV2)

FCH:	102050239(CAV2)

EGZ:	104133418(CAV2)

NNI:	104013627(CAV2)

PCRI:

104028921(CAV2)

PLET:

104613775(CAV2)

EHS:	104502965(CAV2)

ACUN:

113491224(CAV2)

TALA:

104355755(CAV2)

PADL:

103917010(CAV2)

AFOR:

103905269(CAV2)

ACHC:

115342018(CAV2)

HALD:

104312607(CAV2)

HLE:	104835869(CAV2)

AGEN:

126044483

GCL:

127017007

CSTI:

104549704(CAV2)

CMAC:

104477471(CAV2)

MUI:	104533668(CAV2)

BREG:

104629358(CAV2)

FGA:	104070469(CAV2)

GSTE:

104263617(CAV2)

LDI:	104342393(CAV2)

MNB:	103781158(CAV2)

NNT:	104402417(CAV2)

SHAB:

115605663(CAV2)

DPUB:

104309191(CAV2)

PGUU:

104469093(CAV2)

ACAR:

104517697(CAV2)

CPEA:

104394687(CAV2)

AVIT:

104276329(CAV2)

RTD:	128904152(CAV2)

CUCA:

104064339(CAV2)

BRHI:

104488097(CAV2)

AAM:	106488129(CAV2)

AROW:

112965502(CAV2)

NPD:	112942327(CAV2)

TGT:	104580429(CAV2)

DNE:	112981588(CAV2)

SCAM:

104153581(CAV2)

ASN:	102368692(CAV2)

AMJ:	102564889(CAV2)

CPOO:

109315617(CAV2)

GGN:

109296356

PSS:	102447339(CAV2)

CMY:	102932255(CAV2)

CCAY:

125630349(CAV2)

DCC:	119840925(CAV2)

CPIC:

101953479(CAV2)

TST:	117876679(CAV2)

CABI:

116819239(CAV2)

MRV:	120395509(CAV2)

ACS:	100560849(cav2) 100562999

ASAO:

132766534 132776255(CAV2)

PVT:	110077035(CAV2) 110078663

SUND:

121923089 121932024(CAV2)

PBI:	103065527 103066484

PMUR:

107284239 107287881(CAV2)

CTIG:

120301440 120305330(CAV2)

TSR:	106557421(CAV2)

PGUT:

117673586(CAV2) 117675508

APRI:

131193306 131202470(CAV2)

PTEX:

113443403

NSS:	113413070(CAV2) 113417705

VKO:	123019913(CAV2) 123029957

PMUA:

114587875 114605517(CAV2)

PRAF:

128404837 128422236(CAV2)

ZVI:	118075486 118090739(CAV2)

HCG:	128327887(CAV2) 128347861

GJA:	107113782(CAV2)

STOW:

125428090 125435641(CAV2)

EMC:	129335907(CAV2) 129346374

XLA:	108698293(XB5932841.L) 108700040(XB5932841.S) 398391(cav2.L) 443832(cav2.S)

XTR:	100496423 548480(cav2)

NPR:	108784481 108788741(CAV2)

RTEM:

120914414 120931876(CAV2)

BBUF:

120977245 120981698(CAV2)

BGAR:

122919509 122927949(CAV2)

MUO:	115462406 115478760(CAV2)

GSH:	117363348 117367013(CAV2)

DRE:	100136849(cav4a) 415240(cav2) 791212(cav4b)

SRX:	107715787 107716639 107737724 107741322 107750272 107753679

SANH:

107657001 107658045 107659543 107665691 107671977 107673446 107679579 107685982

SGH:	107562459 107574002 107576490 107580652 107584495

CCAR:

109065154 109065157 109073710 109081482 109088581 109097500

CAUA:

113043261 113051100 113055361 113066756 113069114 113094669

CGIB:

127944495 127947469 128011488 128013927 128015193 128022141

PTET:

122328744(zgc:158296) 122330591(cav2) 122354398(zgc:172270)

LROH:

127154980(cav4b) 127157124(cav2) 127166884 127173361(cav4a)

OMC:	131531819(cav4b) 131533945(cav2) 131543064 131549800(cav4a)

PPRM:

120459091(cav2) 120462894(zgc:158296) 120480744(zgc:172270)

RKG:	130081670(cav4b) 130083531(cav4a) 130085329(cav2) 130087606

MAMB:

125246985(cav2) 125256558(cav4a) 125260794(cav4b) 125273259

CIDE:

127504790 127506705 127514445 127522671

MASI:

127419443 127419938 127426128 127428002 127436270 127437710

TROS:

130545469(cav4b) 130551900(cav2) 130571395(cav4a)

TDW:	130409813(cav4b) 130410535(cav4a) 130414229(cav2)

MANU:

129427754(cav4a) 129431082(cav4b) 129434128(cav2)

IPU:	108269359 108275955(cav4b) 108281023(cav4a)

IFU:	128611793(cav2) 128619207(cav4b) 128624761(cav4a)

PHYP:

113529636 113530656 113539637 113546604(cav2)

SMEO:

124386639(cav2) 124399228(zgc:158296) 124402398(zgc:172270)

TFD:	113648582(cav4a) 113651475(cav2) 113658246(cav4b)

TVC:	132837731(cav4a) 132856171(cav2) 132862764(cav4b)

AMEX:

103023460 103028678(cav2) 103029205 103043623

CMAO:

118799629(zgc:172270) 118806732(cav2) 118807555 118822530(zgc:158296)

EEE:	113569401 113578900 113584983 113587969

CHAR:

105894128(zgc:158296) 105897959(zgc:172270) 105904651

TRU:	100137153(cav2) 101069917

TFS:	130524619(cav4a) 130536311(cav2)

TNG:	GSTEN00027475G001 GSTEN00029817G001

LCO:	104920517 104930495 104930774 104931753(cav2)

NCC:	104952899 104956273 104965626 104966248

TBEN:

117489758 117489773(zgc:172270) 117494390(zgc:158296) 117497331(cav2)

CGOB:

115008187 115008700 115009156(cav2) 115011086

PGEO:

117446174 117447066(zgc:172270) 117448164(cav2) 117450159(zgc:158296)

GACU:

117532898(zgc:158296) 117538695(cav2) 117548116(zgc:172270) 117551012

EMAC:

134871597(cav4b) 134882986(cav2) 134883338(cav4a) 134883544

ELY:	117256315(zgc:172270) 117257088 117257983(zgc:158296) 117262629(cav2)

EFO:	125886769(cav2) 125891555(cav4b) 125892775 125896694(cav4a)

PLEP:

121939000 121950662(cav2) 121956181 121958418(zgc:172270)

SLUC:

116036393(cav2) 116040623(zgc:158296) 116041703 116051572(zgc:172270)

ECRA:

117943212(zgc:172270) 117943704 117947247(zgc:158296) 117949309(cav2)

ESP:	116688249 116688419 116691899 116693808(cav2)

PFLV:

114553726 114554233 114559192 114560264(cav2)

GAT:	120809625(cav2) 120829603(zgc:158296) 120834970 120835477(zgc:172270)

PPUG:

119196704(cav2) 119223241(zgc:158296) 119230015(zgc:172270)

AFB:	129100389(cav4b) 129106355 129106412(cav4a) 129108668(cav2)

CLUM:

117730537(zgc:172270) 117731161 117731765(cav2) 117733837(zgc:158296)

PSWI:

130208631 130208925

MSAM:

119886802(zgc:172270) 119886975 119894034(cav2)

SCHU:

122861705(zgc:172270) 122874649(cav2)

CUD:	121507296 121507376(zgc:172270) 121515262(cav2) 121518208(zgc:158296)

ALAT:

119021576 119021934(zgc:172270) 119022264(zgc:158296) 119025033(cav2)

MZE:	101465229 101466353(cav2) 101469442 101475329

ONL:	100691279 100693947 100709253 100709440(cav2)

OAU:	116315606(zgc:158296) 116317511(cav2) 116333925 116334269(zgc:172270)

OLA:	101156574 101164882 110014685

OML:	112139170(cav2) 112144785(zgc:172270) 112145542 112159748(zgc:158296)

CSAI:

133444599(cav2) 133449354 133449382(cav4a) 133456571

XMA:	102219207 102223913 102225266 102233295(cav2)

XCO:	114135819 114136168 114143439(cav2) 114148419

XHE:	116709598(cav2) 116710253 116711114 116720553

PRET:

103464552 103465217 103465631(cav2) 103466888

PFOR:

103137395 103150613(cav2) 103150700 103151330

PLAI:

106947943 106950393 106953502(cav2) 106959006

PMEI:

106910273 106918478 106919601 106923748

GAF:	122833923(zgc:172270) 122834073 122836084(cav2) 122836805(zgc:158296)

PPRL:

129353368(cav2) 129355772 129358424(cav4a) 129371707(cav4b)

CVG:	107083229(cav2) 107093336 107096117

CTUL:

119775100(zgc:172270) 119779964 119780437(cav2)

GMU:	124856557 124857020(cav4a) 124874684(cav4b) 124877888(cav2)

NFU:	107385186 107388348(cav2) 107391351

KMR:	108231190(zgc:172270) 108233071(zgc:158296) 108235698 108248202(cav2)

ALIM:

106516099 106517961 106518849(cav2) 106527002

NWH:	119412356(zgc:172270) 119412524 119416054(cav2) 119417742(zgc:158296)

AOCE:

111568685 111572783(cav2) 111574955 111575501

MCEP:

125007027 125007179(cav4a) 125015428(cav2) 125018710(cav4b)

CSEM:

103379589(cav2) 103384571 103385743

POV:	109623973(cav2) 109630680 109638468

SSEN:

122768850(zgc:172270) 122775959(cav2) 122776939(zgc:158296)

HHIP:

117761978(zgc:172270) 117763015(cav2) 117764283(zgc:158296)

HSP:	118104929(cav4a) 118110063(cav2) 118110409(cav4b)

SMAU:

118310095(cav4a) 118315661(cav2) 118316843(cav4b)

LCF:	108882686(cav4b) 108889884(cav4a) 108893998

SDU:	111220534(cav2) 111222816 111230734

SLAL:

111653214 111657843 111672165(cav2)

XGL:	120783152(zgc:172270) 120793752(cav2) 120804429(zgc:158296)

HCQ:	109530889(cav2) 109531487

SSCV:

125970190 125976966

SBIA:

133502680(cav2) 133507924(cav4a)

PEE:	133402678(cav2) 133409073(cav4a)

PTAO:

133478156(cav2) 133483921(cav4a)

BPEC:

110155122(cav2) 110158094 110158095 110168663

MALB:

109956322(cav2) 109958196 109958948 109970394

BSPL:

114855702 114856371(cav4a) 114857547(cav2) 114858753(cav4b)

SJO:	128355261 128355801(cav4a) 128357222(cav4b) 128358607(cav2)

SASA:

100196537(cav2) 106561555 106565578 106573118(cav2) 106583184 106583537(CAV2)

STRU:

115149866 115150338 115152328 115197556 115207889 115208087

OTW:	112218853(cav2) 112223176 112252652 112254822 112255282 112262828

OMY:	110494092 110495180 110499503(cav2) 110524381 110528334

OGO:	123993101 124004019 124004163 124019627 124033589(cav2)

ONE:	115109664 115115861 115131484 115133969 115142346

OKI:	109867831 109873058 109889627(cav2) 109891283 109891577 109901109

OKE:	118389492 118389524 118395947(cav2) 118400967

SALP:

111952970(cav2) 111962724 111963932 111969281 111970311 111970678

SNH:	120021261 120025895 120041136 120053523(cav2) 120064749 120065528

CCLU:

121531534 121531676(cav2) 121575057 121575218 121578167 121578516

ELS:	105018294(cav2) 105026476 106024720 114828880 114828881

SFM:	108918385 108918726 108931440

PKI:	111836012 111837470 111842436

AANG:

118208364 118211001(zgc:158296) 118211630 118218765 118231128(cav2)

LOC:	102684934(cav2) 102696115

PSPA:

121298329 121305472(zgc:158296) 121318230 121320261 121329362

ARUT:

117411840 117413724 117415282 117419739 117964005 117964069

PSEX:

120534108(cav2) 120542928(zgc:158296)

LCM:	102354291 102362627 102365324(CAV2)

CMK:	103176736 103179353

RTP:	109912147(cav2) 109923579 125485113(cav4a)

CPLA:

122557483 122559225(zgc:172270) 122559683(cav2)

HOC:	132813926 132822164 132824925(cav2)

LERI:

129704563(cav4a) 129706513(cav2)

PMRN:

116947523(CAV2)

LRJ:	133351692(CAV2)

BBEL:

TPAL:

EAF:

VDE:

VJA:

UDV:

CEL:	CELE_C56A3.7(cav-2)

CBR:	CBG_06676(Cbr-cav-2)

NAI:	NECAME_07765

CRG:	105323034 117691050

CANU:

OED:

MYI:

PMAX:

MMER:

Reference

PMID:19427337

Authors

Kwon H, Jeong K, Hwang EM, Park JY, Hong SG, Choi WS, Pak Y

Title

Caveolin-2 regulation of STAT3 transcriptional activation in response to insulin.

Journal

Biochim Biophys Acta 1793:1325-33 (2009)
DOI:10.1016/j.bbamcr.2009.04.015

Sequence

[rno:363425]

Reference

PMID:8552590

Authors

Scherer PE, Okamoto T, Chun M, Nishimoto I, Lodish HF, Lisanti MP

Title

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.

Journal

Proc Natl Acad Sci U S A 93:131-5 (1996)
DOI:10.1073/pnas.93.1.131

Sequence

[hsa:858]

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