KEGG   ORTHOLOGY: K13240
Entry
K13240                      KO                                     

Name
NOS1
Definition
nitric-oxide synthase, brain [EC:1.14.13.39]
Pathway
ko00220  Arginine biosynthesis
ko00330  Arginine and proline metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko04020  Calcium signaling pathway
ko04145  Phagosome
ko04371  Apelin signaling pathway
ko04713  Circadian entrainment
ko04730  Long-term depression
ko04926  Relaxin signaling pathway
ko04970  Salivary secretion
ko05010  Alzheimer disease
ko05014  Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    K13240  NOS1; nitric-oxide synthase, brain
   00330 Arginine and proline metabolism
    K13240  NOS1; nitric-oxide synthase, brain
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    K13240  NOS1; nitric-oxide synthase, brain
   04020 Calcium signaling pathway
    K13240  NOS1; nitric-oxide synthase, brain
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K13240  NOS1; nitric-oxide synthase, brain
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    K13240  NOS1; nitric-oxide synthase, brain
  09154 Digestive system
   04970 Salivary secretion
    K13240  NOS1; nitric-oxide synthase, brain
  09156 Nervous system
   04730 Long-term depression
    K13240  NOS1; nitric-oxide synthase, brain
  09159 Environmental adaptation
   04713 Circadian entrainment
    K13240  NOS1; nitric-oxide synthase, brain
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K13240  NOS1; nitric-oxide synthase, brain
   05014 Amyotrophic lateral sclerosis
    K13240  NOS1; nitric-oxide synthase, brain
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     K13240  NOS1; nitric-oxide synthase, brain
Other DBs
RN: R00111 R00557 R00558
GO: 0004517
Genes
HSA: 4842(NOS1)
PTR: 467139(NOS1)
PPS: 100996089(NOS1)
GGO: 101147071(NOS1)
PON: 100433069(NOS1)
NLE: 100597250(NOS1)
MCC: 693781(NOS1)
MCF: 102123521(NOS1)
RRO: 104675533(NOS1)
RBB: 108539288(NOS1)
CJC: 100895717(NOS1)
SBQ: 101034544(NOS1)
MMU: 18125(Nos1)
MCAL: 110294416(Nos1)
MPAH: 110312876(Nos1)
RNO: 24598(Nos1)
MUN: 110551884(Nos1)
CGE: 100758127(Nos1)
NGI: 103745523(Nos1)
HGL: 101711993(Nos1)
CCAN: 109686387(Nos1)
OCU: 100009243(NOS1)
TUP: 102480558(NOS1)
CFA: 477498(NOS1)
VVP: 112932933(NOS1)
AML: 100468087(NOS1)
UMR: 103661304(NOS1)
UAH: 113266817(NOS1)
ORO: 101375441(NOS1)
ELK: 111156411
FCA: 101100342(NOS1)
PTG: 102962715(NOS1)
PPAD: 109277571(NOS1)
AJU: 106971710(NOS1)
BTA: 536132(NOS1)
BOM: 102280537(NOS1)
BIU: 109571319(NOS1)
BBUB: 102400136(NOS1)
CHX: 102185490(NOS1)
OAS: 443533(NOS1)
SSC: 100520934(NOS1)
CFR: 102508946(NOS1)
CDK: 105104911(NOS1)
BACU: 103008209(NOS1)
LVE: 103090138(NOS1)
OOR: 101273057(NOS1)
DLE: 111186931(NOS1)
PCAD: 102991967(NOS1)
ECB: 100051079(NOS1)
EPZ: 103547950(NOS1)
EAI: 106839766(NOS1)
MYB: 102260489(NOS1)
MYD: 102763635(NOS1)
MNA: 107528483(NOS1)
HAI: 109382238(NOS1)
DRO: 112310614(NOS1)
PALE: 102884569(NOS1)
RAY: 107513162(NOS1)
MJV: 108397443(NOS1)
LAV: 100673992(NOS1)
TMU: 101342004
MDO: 100013712(NOS1)
SHR: 100921140(NOS1)
PCW: 110222812(NOS1)
OAA: 100093259(NOS1)
GGA: 427721(NOS1)
MGP: 100538441(NOS1)
CJO: 107321466(NOS1)
NMEL: 110406170(NOS1)
APLA: 101798766(NOS1)
ACYG: 106045554(NOS1)
TGU: 100231414(NOS1) 116807264
LSR: 110474155(NOS1)
SCAN: 103818226(NOS1)
GFR: 102042821(NOS1)
FAB: 101820761(NOS1)
PHI: 102106809(NOS1)
PMAJ: 107211573(NOS1)
CCAE: 111936662(NOS1)
CCW: 104695038(NOS1)
ETL: 114071586(NOS1)
FPG: 101916747(NOS1)
FCH: 102047821(NOS1)
CLV: 102093432(NOS1)
EGZ: 104129871(NOS1)
NNI: 104010553(NOS1)
ACUN: 113486129(NOS1)
PADL: 103913684(NOS1)
AAM: 106493898(NOS1)
ASN: 102380334(NOS1)
AMJ: 102561243(NOS1)
PSS: 102444149(NOS1)
CMY: 102941829(NOS1)
CPIC: 101937660(NOS1)
ACS: 100562233(nos1)
PVT: 110090104(NOS1)
PBI: 103052972(NOS1)
PMUR: 107295430(NOS1)
PMUA: 114587067(NOS1)
GJA: 107112296(NOS1)
XLA: 108707179(nos1.S) 373705(nos1.L)
XTR: 100497595(nos1)
NPR: 108785232(NOS1)
DRE: 60658(nos1)
SRX: 107726721 107755829(nos1)
SANH: 107668720 107704495(nos1)
SGH: 107599142(nos1) 107599638
IPU: 108255344(nos1)
PHYP: 113537215(nos1)
AMEX: 103046065(nos1)
EEE: 113577767(nos1)
TRU: 101066909(nos1)
LCO: 104923687(nos1)
NCC: 104967506(nos1)
MZE: 101485683(nos1)
ONL: 100534582(nos1)
OLA: 100049502(nos1)
XMA: 102233853(nos1)
XCO: 114154866(nos1)
PRET: 103469871(nos1)
CVG: 107087335(nos1)
NFU: 107386248(nos1)
KMR: 108246938(nos1)
ALIM: 106519449(nos1)
AOCE: 111572539(nos1)
CSEM: 103396877 103397851(nos1)
POV: 109637139(nos1)
LCF: 108903114(nos1)
SDU: 111227324(nos1)
SLAL: 111663111(nos1)
HCQ: 109525272(nos1)
BPEC: 110155016(nos1)
MALB: 109959109(nos1)
SASA: 100136388(nos1) 106585241
ELS: 105031277(nos1)
SFM: 108927312(nos1)
PKI: 111851114 111852748(nos1)
LCM: 102348281(NOS1)
CMK: 103184386(nos1)
RTP: 109914181(nos1) 109922224
CIN: 100183039
DME: Dmel_CG6713(Nos)
DER: 6542987
DSE: 6612066
DSI: Dsimw501_GD22223(Dsim_GD22223)
DAN: 6496893
DSR: 110183462
DPE: 6596585
DMN: 108163699
DWI: 6641760
DAZ: 108609612
DNV: 108658145
DHE: 111601524
DVI: 6629111
MDE: 101891936
LCQ: 111681704
AAG: 5572370
AME: 503861(NOS)
BIM: 100749227
BTER: 100650517
CCAL: 108625325
OBB: 114871710
SOC: 105200228
MPHA: 105829748
AEC: 105149468
ACEP: 105625167
PBAR: 105432905
VEM: 105557978
HST: 105183230
DQU: 106744004
CFO: 105250272
LHU: 105675559
PGC: 109856190
OBO: 105286125
PCF: 106793080
NVI: 100313941(Nos)
CSOL: 105360744
MDL: 103570884
TCA: 655549
DPA: 109546644
NVL: 108558954
BMOR: 100144542(NOS2) 692510(NOS1)
API: 100160390
DNX: 107172687
AGS: 114128082
RMD: 113551041
BTAB: 109031807
CLEC: 106661589
ZNE: 110828058
FCD: 110850636
TUT: 107370056
DPTE: 113792010
PTEP: 107440636
PCAN: 112563084
CRG: 105322950
MYI: 110460719
LAK: 106169208
NVE: 5511062
EPA: 110253339
PDAM: 113685754
HMG: 101240122
 » show all
Reference
PMID:7528745
  Authors
Hall AV, Antoniou H, Wang Y, Cheung AH, Arbus AM, Olson SL, Lu WC, Kau CL, Marsden PA
  Title
Structural organization of the human neuronal nitric oxide synthase gene (NOS1).
  Journal
J Biol Chem 269:33082-90 (1994)
  Sequence
[hsa:4842]

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