KEGG   ORTHOLOGY: K13260
Entry
K13260                      KO                                     

Name
CYP81E
Definition
isoflavone/4'-methoxyisoflavone 2'-hydroxylase [EC:1.14.14.90 1.14.14.89]
Pathway
ko00943  Isoflavonoid biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00943 Isoflavonoid biosynthesis
    K13260  CYP81E; isoflavone/4'-methoxyisoflavone 2'-hydroxylase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K13260  CYP81E; isoflavone/4'-methoxyisoflavone 2'-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.89  4'-methoxyisoflavone 2'-hydroxylase
     K13260  CYP81E; isoflavone/4'-methoxyisoflavone 2'-hydroxylase
    1.14.14.90  isoflavone 2'-hydroxylase
     K13260  CYP81E; isoflavone/4'-methoxyisoflavone 2'-hydroxylase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, plant type
  CYP81 family
   K13260  CYP81E; isoflavone/4'-methoxyisoflavone 2'-hydroxylase
Other DBs
RN: R06560 R06561 R06606 R06607 R07371 R07746
GO: 0033773 0047957
Genes
CPAP: 110822377
CIT: 102624248
CIC: CICLE_v10025420mg
TCC: 18601853 18601857 18601860 18601861
GRA: 105763176 105789260
GHI: 107916731 107936806 107945765 107953970
GAB: 108470315 108476762
DZI: 111282012 111282131 111282224 111282978 111283036 111283932 111308417
EGR: 104420349
GMX: 100784650 100790507 100797371 100798269 100801092(CYP81E11) 100804509 100807819 100811727 100812102
LJA: Lj0g3v0281229.2(Lj0g3v0281229.2) Lj2g3v1925640.1(Lj2g3v1925640.1) Lj4g3v0189840.1(Lj4g3v0189840.1) Lj4g3v0189850.1(Lj4g3v0189850.1)
POP: 18101164
SLY: 101250559
SPEN: 107011466
SOT: 102601877
NTA: 107782936
NSY: 104238470
NTO: 104120546
NAU: 109213256
INI: 109151908
OEU: 111367220
DCR: 108196113
AG: BAA22422(CYP81E1)
 » show all
Reference
PMID:9790908 (CYP81E1)
  Authors
Akashi T, Aoki T, Ayabe S
  Title
CYP81E1, a cytochrome P450 cDNA of licorice (Glycyrrhiza echinata L.), encodes isoflavone 2'-hydroxylase.
  Journal
Biochem Biophys Res Commun 251:67-70 (1998)
DOI:10.1006/bbrc.1998.9414
  Sequence
Reference
PMID:14617078 (CYP81E7 CYP81E8)
  Authors
Liu CJ, Huhman D, Sumner LW, Dixon RA.
  Title
Regiospecific hydroxylation of isoflavones by cytochrome p450 81E enzymes from Medicago truncatula.
  Journal
Plant J 36:471-84 (2003)
DOI:10.1046/j.1365-313X.2003.01893.x
  Sequence

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