KEGG   ORTHOLOGY: K13310
Entry
K13310                      KO                                     
Symbol
desV, eryCI
Name
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase [EC:2.6.1.106]
Pathway
map00523  Polyketide sugar unit biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01250  Biosynthesis of nucleotide sugars
Module
M00797  dTDP-D-desosamine biosynthesis
Reaction
R06426  dTDP-3-amino-3,4,6-trideoxy-D-glucose:2-oxoglutarate aminotransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K13310  desV, eryCI; dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.106  dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
     K13310  desV, eryCI; dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
Genes
PTRL: OU419_09855
TFV: IDJ81_02380
SRN: A4G23_00481(fdtB_1)
SPAV: Spa2297_32850
SHAW: CEB94_04710
SGX: H4W23_25510
SFB: CP974_02505
SCOA: QU709_45620
SEN: SACE_0734(eryCI)
ACTI: UA75_17820
ACAD: UA74_17285
AHG: AHOG_15460(fdtB2)
CROS: N8J89_11400
PLAB: C6361_24070
PLAT: C6W10_35925
AEY: CDG81_13130
PBAJ: LRS13_04530
LUB: TBR22_A49060
AG: AAC68680(desV)
 » show all
Reference
PMID:17456741
  Authors
Burgie ES, Thoden JB, Holden HM
  Title
Molecular architecture of DesV from Streptomyces venezuelae: a PLP-dependent transaminase involved in the biosynthesis of the unusual sugar desosamine.
  Journal
Protein Sci 16:887-96 (2007)
DOI:10.1110/ps.062711007
Reference
PMID:16187386
  Authors
Szu PH, He X, Zhao L, Liu HW
  Title
Biosynthesis of TDP-D-desosamine: identification of a strategy for C4 deoxygenation.
  Journal
Angew Chem Int Ed Engl 44:6742-6 (2005)
DOI:10.1002/anie.200501998
Reference
PMID:9770448
  Authors
Xue Y, Zhao L, Liu HW, Sherman DH
  Title
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.
  Journal
Proc Natl Acad Sci U S A 95:12111-6 (1998)
DOI:10.1073/pnas.95.21.12111
  Sequence
[ag:AAC68680]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (8)   
   KEGG MODULE (1)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (19)   
   KEGG GENES (18)   
   OC (1)   
Literature (3)   
   PubMed (3)   
All databases (37)   

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