KEGG   ORTHOLOGY: K13368Help
Entry
K13368                      KO                                     

Name
HSD17B2
Definition
17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239]
Pathway
ko00140  Steroid hormone biosynthesis
ko01100  Metabolic pathways
ko04913  Ovarian steroidogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     K13368  HSD17B2; 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
BRITE hierarchy
Other DBs
RN: R01836 R02352 R02353 R04681 R04682 R08945 R08980
GO: 0004303 0050327
Genes
HSA: 3294(HSD17B2)
PTR: 454269(HSD17B2)
PPS: 100983435(HSD17B2)
GGO: 101131453(HSD17B2)
PON: 100456547(HSD17B2)
NLE: 100588757(HSD17B2)
MCC: 714282(HSD17B2)
MCF: 102119721(HSD17B2)
CSAB: 103233373(HSD17B2)
RRO: 104671622(HSD17B2)
RBB: 108521311(HSD17B2)
CJC: 100390710(HSD17B2)
SBQ: 101030366(HSD17B2)
MMU: 15486(Hsd17b2)
MCAL: 110299663(Hsd17b2)
MPAH: 110337701(Hsd17b2)
RNO: 79243(Hsd17b2)
MUN: 110550260(Hsd17b2)
CGE: 100751897(Hsd17b2)
NGI: 103748738(Hsd17b2)
HGL: 101719685(Hsd17b2)
OCU: 100358604(HSD17B2)
TUP: 102481564(HSD17B2)
CFA: 489690(HSD17B2)
VVP: 112912332(HSD17B2)
AML: 100484508(HSD17B2)
UMR: 103662132(HSD17B2)
UAH: 113252538(HSD17B2)
ORO: 101379076(HSD17B2)
FCA: 101085592(HSD17B2)
PTG: 102958819(HSD17B2)
PPAD: 109245636(HSD17B2)
AJU: 106984011(HSD17B2)
BTA: 515710(HSD17B2)
BOM: 102278674(HSD17B2)
BIU: 109572993(HSD17B2)
BBUB: 102406091(HSD17B2)
CHX: 102182621(HSD17B2)
OAS: 100913161(HSD17B2)
SSC: 100312973(HSD17B2)
CFR: 102514993(HSD17B2)
CDK: 105089442(HSD17B2)
BACU: 103014202(HSD17B2)
LVE: 103070446(HSD17B2)
OOR: 101284697(HSD17B2)
DLE: 111179344(HSD17B2)
PCAD: 102984629(HSD17B2)
ECB: 100146214(HSD17B2)
EPZ: 103558215(HSD17B2)
EAI: 106832532(HSD17B2)
MYB: 102260774(HSD17B2)
MYD: 102751454(HSD17B2)
MNA: 107525681(HSD17B2)
HAI: 109378375(HSD17B2)
DRO: 112300652(HSD17B2)
PALE: 102882881(HSD17B2)
RAY: 107521360(HSD17B2)
MJV: 108400471(HSD17B2)
LAV: 100673988(HSD17B2)
TMU: 101341742
MDO: 100031815(HSD17B2)
SHR: 100921563(HSD17B2)
PCW: 110212686(HSD17B2)
OAA: 100076931(HSD17B2)
GGA: 415807(HSD17B2)
MGP: 100549838(HSD17B2)
CJO: 107319415(HSD17B2)
NMEL: 110404501(HSD17B2)
APLA: 101792379(HSD17B2)
ACYG: 106044875(HSD17B2)
TGU: 100228039(HSD17B2)
LSR: 110476239(HSD17B2)
SCAN: 103816732(HSD17B2)
GFR: 102039377(HSD17B2)
FAB: 101810951(HSD17B2)
PHI: 102103079(HSD17B2)
PMAJ: 107209789(HSD17B2)
CCAE: 111934744(HSD17B2)
CCW: 104691825(HSD17B2)
ETL: 114066564(HSD17B2)
FPG: 101915382(HSD17B2)
FCH: 102048922(HSD17B2)
CLV: 102095570(HSD17B2)
EGZ: 104133743(HSD17B2)
NNI: 104014591(HSD17B2)
ACUN: 113484357(HSD17B2)
PADL: 103923867(HSD17B2)
AAM: 106483270(HSD17B2)
ASN: 102375872(HSD17B2)
AMJ: 102574309(HSD17B2)
PSS: 102453984(HSD17B2)
CMY: 102941631(HSD17B2)
CPIC: 101941193(HSD17B2)
ACS: 103282091
PVT: 110090097(HSD17B2)
PBI: 103058540(HSD17B2)
PMUR: 107287717(HSD17B2)
PMUA: 114602206(HSD17B2)
GJA: 107109831(HSD17B2)
XLA: 108714085(hsd17b2.L)
XTR: 100497002(hsd17b2)
NPR: 108786564(HSD17B2)
DRE: 449537(hsd17b2)
SRX: 107723978
SGH: 107555707
IPU: 108275401(Hsd17b2)
PHYP: 113529589
AMEX: 103032973(hsd17b2)
EEE: 113573186
TRU: 101071919
LCO: 104938964(hsd17b2)
AOCE: 111585754
CSEM: 103379612(hsd17b2)
LCF: 108885234
SDU: 111233733
SLAL: 111647408
BPEC: 110162637(hsd17b2)
MALB: 109969153(hsd17b2)
SASA: 106561531(hsd17b2)
OTW: 112218829(hsd17b2)
SALP: 111962699(hsd17b2)
ELS: 105018101(hsd17b2)
LCM: 102360275(HSD17B2)
CMK: 103191276
SPU: 755047
TUT: 107365892
PTEP: 107442495
PCAN: 112559141
CRG: 105342689
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Smuc T, Rizner TL
  Title
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines.
  Journal
Chem Biol Interact 178:228-33 (2009)
DOI:10.1016/j.cbi.2008.10.038
Reference
  Authors
Plante J, Simard M, Rantakari P, Cote M, Provost PR, Poutanen M, Tremblay Y
  Title
Epithelial cells are the major site of hydroxysteroid (17beta) dehydrogenase 2 and androgen receptor expression in fetal mouse lungs during the period overlapping the surge of surfactant.
  Journal
J Steroid Biochem Mol Biol 117:139-45 (2009)
DOI:10.1016/j.jsbmb.2009.08.006

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