KEGG   ORTHOLOGY: K13369Help
Entry
K13369                      KO                                     

Name
HSD17B6
Definition
17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239]
Pathway
ko00140  Steroid hormone biosynthesis
ko00830  Retinol metabolism
ko01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
    1.1.1.105  all-trans-retinol dehydrogenase (NAD+)
     K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
    1.1.1.239  3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
     K13369  HSD17B6; 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
BRITE hierarchy
Other DBs
RN: R01836 R02124 R02352 R02353 R04681 R04682 R08945 R08980
GO: 0004303 0004745 0050327
Genes
HSA: 8630(HSD17B6)
PTR: 452001
PPS: 100996145(HSD17B6)
GGO: 101153072
PON: 100458219(HSD17B6)
NLE: 100606923
MCC: 713549(HSD17B6)
MCF: 101926544(HSD17B6)
CSAB: 103238543(HSD17B6)
RRO: 104673659(HSD17B6)
RBB: 108516069(HSD17B6)
CJC: 100387390(HSD17B6)
SBQ: 101054253(HSD17B6)
MMU: 27400(Hsd17b6)
MCAL: 110303948
MPAH: 110326955(Hsd17b6)
RNO: 100362350 286964(Hsd17b6)
CGE: 100762147(Hsd17b6)
NGI: 103730224(Hsd17b6)
HGL: 101699287(Hsd17b6)
CCAN: 109686095
TUP: 102485005(HSD17B6)
CFA: 481118(HSD17B6)
VVP: 112922366(HSD17B6)
AML: 100474694(HSD17B6)
UMR: 103656323(HSD17B6)
UAH: 113256406(HSD17B6)
ORO: 101368715(HSD17B6)
ELK: 111160200
FCA: 101088341(HSD17B6)
PTG: 102971783(HSD17B6)
PPAD: 109270351(HSD17B6)
AJU: 106986922(HSD17B6)
BTA: 533086(HSD17B6)
BOM: 102283510(HSD17B6)
BIU: 109559345
BBUB: 102407967
CHX: 102185066(HSD17B6)
OAS: 101105400
SSC: 100620470
CFR: 102508382
CDK: 105096750
BACU: 103008169(HSD17B6)
LVE: 103076064(HSD17B6)
OOR: 101278484(HSD17B6)
DLE: 111173857(HSD17B6)
PCAD: 102988625
ECB: 100052840
EPZ: 103545357 103565330(HSD17B6)
EAI: 106832977(HSD17B6)
MYD: 102770923
PALE: 102883634(HSD17B6)
RAY: 107521200(HSD17B6)
MJV: 108402619
LAV: 100657790
TMU: 101345897
SHR: 100931687
PCW: 110211084
CMY: 102944543(HSD17B6)
ACS: 100564174(hsd17b6)
PMUR: 107293735
TSR: 106545328(HSD17B6)
GJA: 107120904(HSD17B6)
XLA: 398882(rdh16.L)
XTR: 100135184(rdh16)
CRG: 105342862
MYI: 110451842
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9188497
  Authors
Biswas MG, Russell DW
  Title
Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate.
  Journal
J Biol Chem 272:15959-66 (1997)
DOI:10.1074/jbc.272.25.15959
  Sequence
[hsa:8630] [rno:286964]
Reference
  Authors
Chetyrkin SV, Hu J, Gough WH, Dumaual N, Kedishvili NY
  Title
Further characterization of human microsomal 3alpha-hydroxysteroid dehydrogenase.
  Journal
Arch Biochem Biophys 386:1-10 (2001)
DOI:10.1006/abbi.2000.2203
  Sequence
[hsa:8630]

DBGET integrated database retrieval system