K13373                      KO                                     

17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:]
ko00100  Steroid biosynthesis
ko00140  Steroid hormone biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko04913  Ovarian steroidogenesis
M00101  Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase
   00140 Steroid hormone biosynthesis
    K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor  17beta-estradiol 17-dehydrogenase
     K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase  3beta-hydroxysteroid 3-dehydrogenase
     K13373  HSD17B7; 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase
Other DBs
RN: R02352 R02353 R04681 R04682 R07495 R08945 R08980 R12405
GO: 0004303 0050576
HSA: 51478(HSD17B7)
PTR: 466046 747814(HSD17B7)
PPS: 100985156(HSD17B7)
GGO: 101137638(HSD17B7)
PON: 100446761(HSD17B7)
NLE: 100587120(HSD17B7)
MCC: 720399
MCF: 102127673(HSD17B7)
CSAB: 103223654(HSD17B7)
RRO: 104656967(HSD17B7)
RBB: 108535633
CJC: 100410416(HSD17B7)
SBQ: 101047238(HSD17B7)
MMU: 15490(Hsd17b7)
MCAL: 110292934(Hsd17b7)
MPAH: 110322287(Hsd17b7)
RNO: 29540(Hsd17b7)
MUN: 110550630(Hsd17b7)
CGE: 100767580(Hsd17b7)
NGI: 103746788(Hsd17b7)
HGL: 101712707(Hsd17b7)
CCAN: 109690973(Hsd17b7)
OCU: 100008778(HSD17B7) 100349261
TUP: 102473205(HSD17B7)
CFA: 609364(HSD17B7)
VVP: 112914306(HSD17B7)
AML: 100477716(HSD17B7)
UMR: 103658287(HSD17B7)
UAH: 113268675(HSD17B7)
ORO: 101368538(HSD17B7)
ELK: 111151061
FCA: 101083482(HSD17B7)
PTG: 102968316(HSD17B7)
PPAD: 109276652(HSD17B7)
AJU: 106986761(HSD17B7)
BTA: 505212(HSD17B7)
BOM: 102266348(HSD17B7)
BIU: 109577890(HSD17B7)
BBUB: 102389083(HSD17B7)
CHX: 102179058(HSD17B7)
OAS: 101110013(HSD17B7)
SSC: 100155418(HSD17B7)
CFR: 102512546(HSD17B7)
CDK: 105092702(HSD17B7)
BACU: 103014331(HSD17B7)
LVE: 103084050(HSD17B7)
OOR: 101286750(HSD17B7)
DLE: 111169243(HSD17B7)
PCAD: 102984493(HSD17B7)
ECB: 100059061(HSD17B7)
EPZ: 103559639(HSD17B7)
EAI: 106823694(HSD17B7)
MYB: 102251181(HSD17B7)
MYD: 102767046(HSD17B7)
MNA: 107535110(HSD17B7)
HAI: 109392309(HSD17B7)
DRO: 112298817(HSD17B7)
PALE: 102892079(HSD17B7)
MJV: 108396655(HSD17B7)
LAV: 100676060 100676343(HSD17B7)
TMU: 101361551
MDO: 100016071(HSD17B7)
SHR: 100926227(HSD17B7)
PCW: 110209887(HSD17B7)
OAA: 114817513(HSD17B7)
GGA: 424367(HSD17B7)
MGP: 100542640(HSD17B7)
CJO: 107317140(HSD17B7)
NMEL: 110402344(HSD17B7)
APLA: 101799136(HSD17B7)
ACYG: 106041628(HSD17B7)
TGU: 100222823(HSD17B7)
LSR: 110478897(HSD17B7)
SCAN: 103824326(HSD17B7)
GFR: 102042580(HSD17B7)
FAB: 101818521(HSD17B7)
PHI: 102107312(HSD17B7)
PMAJ: 107198613(HSD17B7)
CCAE: 111932684(HSD17B7)
CCW: 104695594(HSD17B7)
ETL: 114067481(HSD17B7)
FPG: 101919410(HSD17B7)
FCH: 102059217(HSD17B7)
CLV: 102097738(HSD17B7)
EGZ: 104132130(HSD17B7)
NNI: 104010459(HSD17B7)
ACUN: 113483111(HSD17B7)
PADL: 103914076(HSD17B7)
AAM: 106499711(HSD17B7)
ASN: 102374189(HSD17B7)
AMJ: 102565865(HSD17B7)
PSS: 102461698(HSD17B7)
CMY: 102944731(HSD17B7)
CPIC: 101953232(HSD17B7)
ACS: 100556465(hsd17b7)
PVT: 110081655(HSD17B7)
PBI: 103063132(HSD17B7)
PMUR: 107302880(HSD17B7)
PMUA: 114598525(HSD17B7)
GJA: 107121042(HSD17B7)
XLA: 734717(hsd17b7.S)
XTR: 548963(hsd17b7)
NPR: 108801354(HSD17B7)
DRE: 768185(hsd17b7)
SANH: 107684349(hsd17b7) 107692446
CCAR: 109091408
IPU: 108271889(hsd17b7)
PHYP: 113538418(hsd17b7)
AMEX: 103035681(hsd17b7)
EEE: 113570462(hsd17b7)
TRU: 101072277 101079626(hsd17b7)
NCC: 104948248(hsd17b7) 104967182
XMA: 102223080(hsd17b7) 102225591
KMR: 108230837(hsd17b7) 108238258
ALIM: 106528419(hsd17b7)
POV: 109625649(hsd17b7) 109644359
BPEC: 110173518(hsd17b7) 110174039
MALB: 109951354(hsd17b7) 109966957
SASA: 106568727
OTW: 112260221
SALP: 111957119(hsd17b7)
ELS: 105024805
SFM: 108935177(hsd17b7)
PKI: 111841069(hsd17b7)
LCM: 102348492(HSD17B7)
CMK: 103180036(hsd17b7)
RTP: 109925128(hsd17b7)
BFO: 118426285
CIN: 100180521
SPU: 588363
APLC: 110976300
SKO: 102804082
PCAN: 112564142
CRG: 105338891
MYI: 110457107
LAK: 106150742
AQU: 100638506
 » show all
Marijanovic Z, Laubner D, Moller G, Gege C, Husen B, Adamski J, Breitling R
Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis.
Mol Endocrinol 17:1715-25 (2003)

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