KEGG   ORTHOLOGY: K13376Help
Entry
K13376                      KO                                     

Name
TGFB2
Definition
transforming growth factor beta-2
Pathway
ko04010  MAPK signaling pathway
ko04060  Cytokine-cytokine receptor interaction
ko04068  FoxO signaling pathway
ko04110  Cell cycle
ko04218  Cellular senescence
ko04350  TGF-beta signaling pathway
ko04380  Osteoclast differentiation
ko04390  Hippo signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05140  Leishmaniasis
ko05142  Chagas disease (American trypanosomiasis)
ko05144  Malaria
ko05145  Toxoplasmosis
ko05146  Amoebiasis
ko05152  Tuberculosis
ko05161  Hepatitis B
ko05166  Human T-cell leukemia virus 1 infection
ko05200  Pathways in cancer
ko05205  Proteoglycans in cancer
ko05206  MicroRNAs in cancer
ko05210  Colorectal cancer
ko05211  Renal cell carcinoma
ko05212  Pancreatic cancer
ko05220  Chronic myeloid leukemia
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
ko05321  Inflammatory bowel disease (IBD)
ko05323  Rheumatoid arthritis
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05414  Dilated cardiomyopathy (DCM)
Module
M00680  TGF-beta signaling
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H00800  Loeys-Dietz syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
   04350 TGF-beta signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
   04390 Hippo signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
   04068 FoxO signaling pathway
    K13376  TGFB2; transforming growth factor beta-2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13376  TGFB2; transforming growth factor beta-2
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    K13376  TGFB2; transforming growth factor beta-2
   04218 Cellular senescence
    K13376  TGFB2; transforming growth factor beta-2
 09150 Organismal Systems
  09158 Development
   04380 Osteoclast differentiation
    K13376  TGFB2; transforming growth factor beta-2
 09160 Human Diseases
  09161 Cancers
   05200 Pathways in cancer
    K13376  TGFB2; transforming growth factor beta-2
   05206 MicroRNAs in cancer
    K13376  TGFB2; transforming growth factor beta-2
   05205 Proteoglycans in cancer
    K13376  TGFB2; transforming growth factor beta-2
   05210 Colorectal cancer
    K13376  TGFB2; transforming growth factor beta-2
   05212 Pancreatic cancer
    K13376  TGFB2; transforming growth factor beta-2
   05225 Hepatocellular carcinoma
    K13376  TGFB2; transforming growth factor beta-2
   05226 Gastric cancer
    K13376  TGFB2; transforming growth factor beta-2
   05220 Chronic myeloid leukemia
    K13376  TGFB2; transforming growth factor beta-2
   05211 Renal cell carcinoma
    K13376  TGFB2; transforming growth factor beta-2
  09162 Immune diseases
   05323 Rheumatoid arthritis
    K13376  TGFB2; transforming growth factor beta-2
   05321 Inflammatiory bowel disease (IBD)
    K13376  TGFB2; transforming growth factor beta-2
  09165 Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K13376  TGFB2; transforming growth factor beta-2
   05414 Dilated cardiomyopathy (DCM)
    K13376  TGFB2; transforming growth factor beta-2
  09166 Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K13376  TGFB2; transforming growth factor beta-2
  09167 Infectious diseases
   05152 Tuberculosis
    K13376  TGFB2; transforming growth factor beta-2
   05166 HTLV-I infection
    K13376  TGFB2; transforming growth factor beta-2
   05161 Hepatitis B
    K13376  TGFB2; transforming growth factor beta-2
   05146 Amoebiasis
    K13376  TGFB2; transforming growth factor beta-2
   05144 Malaria
    K13376  TGFB2; transforming growth factor beta-2
   05145 Toxoplasmosis
    K13376  TGFB2; transforming growth factor beta-2
   05140 Leishmaniasis
    K13376  TGFB2; transforming growth factor beta-2
   05142 Chagas disease (American trypanosomiasis)
    K13376  TGFB2; transforming growth factor beta-2
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and growth factors
    K13376  TGFB2; transforming growth factor beta-2
   00536 Glycosaminoglycan binding proteins
    K13376  TGFB2; transforming growth factor beta-2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00680  TGF-beta signaling
     K13376  TGFB2; transforming growth factor beta-2
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K13376  TGFB2; transforming growth factor beta-2
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Growth factors/receptors
   K13376  TGFB2; transforming growth factor beta-2
BRITE hierarchy
Genes
HSA: 7042(TGFB2)
PTR: 457742(TGFB2)
PPS: 100985755(TGFB2)
GGO: 101125504(TGFB2)
PON: 100461291(TGFB2)
NLE: 100596183(TGFB2)
MCC: 707540(TGFB2)
MCF: 101925182(TGFB2)
CSAB: 103230082(TGFB2)
RRO: 104662252(TGFB2)
RBB: 108528282(TGFB2)
CJC: 100390586(TGFB2)
SBQ: 101044624(TGFB2)
MMU: 21808(Tgfb2)
RNO: 81809(Tgfb2)
CGE: 100774918(Tgfb2)
NGI: 103728817(Tgfb2) 103728866
HGL: 101707457(Tgfb2)
CCAN: 109698650(Tgfb2)
OCU: 100009371(TGFB2)
TUP: 102500482(TGFB2)
CFA: 488596(TGFB2)
AML: 100463584(TGFB2)
UMR: 103658194(TGFB2)
ORO: 101380860(TGFB2)
FCA: 101093414(TGFB2)
PTG: 102951894(TGFB2)
AJU: 106979500(TGFB2)
BTA: 534069(TGFB2)
BOM: 102283491(TGFB2)
BIU: 109570509(TGFB2)
PHD: 102317456(TGFB2)
CHX: 100861228(TGFB2)
OAS: 554322(TGFB2)
SSC: 397084(TGFB2)
CFR: 102505811(TGFB2)
CDK: 105100091(TGFB2)
BACU: 103001453(TGFB2)
LVE: 103070826(TGFB2)
OOR: 101276254(TGFB2)
ECB: 100050377(TGFB2)
EPZ: 103543045(TGFB2)
EAI: 106836714(TGFB2)
MYB: 102250887(TGFB2)
MYD: 102755920(TGFB2)
HAI: 109381205(TGFB2)
RSS: 109453108(TGFB2)
PALE: 102881295(TGFB2)
LAV: 100656534(TGFB2)
TMU: 101347669
MDO: 100017548(TGFB2)
SHR: 100914910(TGFB2)
OAA: 100080176(TGFB2)
GGA: 421352(TGFB2)
MGP: 100549559(TGFB2)
CJO: 107311051(TGFB2)
APLA: 101791629(TGFB2) 101794148(TGFB2)
ACYG: 106031565(TGFB2)
TGU: 100231617(TGFB2)
GFR: 102037698(TGFB2)
FAB: 101814341(TGFB2)
PHI: 102114598(TGFB2)
PMAJ: 107202393(TGFB2)
CCW: 104685626(TGFB2)
FPG: 101917357(TGFB2)
FCH: 102047778(TGFB2)
CLV: 102085196(TGFB2)
EGZ: 104133428(TGFB2)
AAM: 106490440(TGFB2)
ASN: 102382227(TGFB2)
AMJ: 102562163(TGFB2)
PSS: 102452874(TGFB2)
CMY: 102946116(TGFB2)
CPIC: 101945771(TGFB2)
ACS: 100568228(tgfb2)
PVT: 110083352 110087066(TGFB2)
GJA: 107110247(TGFB2) 107115203
XLA: 108717706(tgfb2.S) 373801(tgfb2.L)
XTR: 100489680(tgfb2)
NPR: 108795797(TGFB2)
DRE: 369194(tgfb2)
IPU: 108268908 108269996(tgfb2)
AMEX: 103026112(tgfb2) 103042476
TRU: 101066787(tgfb2) 101074584
LCO: 104925539 104936633(tgfb2)
NCC: 104945388
MZE: 101466107 101469764(tgfb2)
OLA: 101155037
XMA: 102223216
PRET: 103471446(tgfb2)
NFU: 107377547
CSEM: 103388748(tgfb2) 103390834
LCF: 108872574 108886089(tgfb2)
HCQ: 109511954 109521921(tgfb2)
BPEC: 110158948 110159085(tgfb2)
ELS: 105007294(tgfb2) 105026733
SFM: 108925415 108929121(tgfb2)
LCM: 102352268 102358422(TGFB2)
CMK: 103172825 103185816(tgfb2)
CIN: 778780(tgfbeta2)
SPU: 588471
APLC: 110979251
SKO: 100329003(TGFbeta2)
AQU: 105312053
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Chen YG
  Title
Endocytic regulation of TGF-beta signaling.
  Journal
Cell Res 19:58-70 (2009)
DOI:10.1038/cr.2008.315
Reference
  Authors
Singla DK, Sun B
  Title
Transforming growth factor-beta2 enhances differentiation of cardiac myocytes from embryonic stem cells.
  Journal
Biochem Biophys Res Commun 332:135-41 (2005)
DOI:10.1016/j.bbrc.2005.04.098
  Sequence
[hsa:7042]
Reference
PMID:3322813
  Authors
de Martin R, Haendler B, Hofer-Warbinek R, Gaugitsch H, Wrann M, Schlusener H, Seifert JM, Bodmer S, Fontana A, Hofer E
  Title
Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.
  Journal
EMBO J 6:3673-7 (1987)
  Sequence
[hsa:7042]

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