KEGG   ORTHOLOGY: K13548
Entry
K13548                      KO                                     

Name
neoA, kanK
Definition
2-deoxy-scyllo-inosamine dehydrogenase [EC:1.1.1.329]
Pathway
ko00524  Neomycin, kanamycin and gentamicin biosynthesis
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    K13548  neoA, kanK; 2-deoxy-scyllo-inosamine dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.329  2-deoxy-scyllo-inosamine dehydrogenase
     K13548  neoA, kanK; 2-deoxy-scyllo-inosamine dehydrogenase
Other DBs
RN: R08892 R10130
Genes
SRN: A4G23_05130(neoA)
AG: BAD95818(neoA) CAF60530(kanK)
Reference
PMID:16506694 (neoA)
  Authors
Kudo F, Yamamoto Y, Yokoyama K, Eguchi T, Kakinuma K
  Title
Biosynthesis of 2-deoxystreptamine by three crucial enzymes in Streptomyces fradiae NBRC 12773.
  Journal
J Antibiot (Tokyo) 58:766-74 (2005)
DOI:10.1038/ja.2005.104
  Sequence
Reference
PMID:15313224 (kanK)
  Authors
Kharel MK, Subba B, Basnet DB, Woo JS, Lee HC, Liou K, Sohng JK
  Title
A gene cluster for biosynthesis of kanamycin from Streptomyces kanamyceticus: comparison with gentamicin biosynthetic gene cluster.
  Journal
Arch Biochem Biophys 429:204-14 (2004)
DOI:10.1016/j.abb.2004.06.009
  Sequence
Reference
  Authors
Kudo F, Eguchi T
  Title
Biosynthetic enzymes for the aminoglycosides butirosin and neomycin.
  Journal
Methods Enzymol 459:493-519 (2009)
DOI:10.1016/S0076-6879(09)04620-5

DBGET integrated database retrieval system