KEGG   ORTHOLOGY: K13578
Entry
K13578                      KO                                     
Symbol
BMPR1B, ALK6, CDw293
Name
bone morphogenetic protein receptor type-1B [EC:2.7.11.30]
Pathway
map04013  MAPK signaling pathway - fly
map04060  Cytokine-cytokine receptor interaction
map04350  TGF-beta signaling pathway
map04360  Axon guidance
map04390  Hippo signaling pathway
map04550  Signaling pathways regulating pluripotency of stem cells
map05418  Fluid shear stress and atherosclerosis
Disease
H00468  Acromesomelic dysplasia, Demirhan type
H00482  Brachydactyly
H02543  Acromesomelic dysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04013 MAPK signaling pathway - fly
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
   04350 TGF-beta signaling pathway
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
   04390 Hippo signaling pathway
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
  09183 Protein families: signaling and cellular processes
   04090 CD molecules
    K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
Protein kinases [BR:ko01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B
CD molecules [BR:ko04090]
 Proteins
  K13578  CDw293, BMPR1B; bone morphogenetic protein receptor, type IB
Other DBs
GO: 0005025
Genes
HSA: 658(BMPR1B)
PTR: 461683(BMPR1B)
PPS: 100991587(BMPR1B)
GGO: 101127602(BMPR1B)
PON: 100444576(BMPR1B)
NLE: 100595681(BMPR1B)
MCC: 705474(BMPR1B)
MCF: 102136230(BMPR1B)
CATY: 105572359(BMPR1B)
PANU: 101008254(BMPR1B)
TGE: 112624237(BMPR1B)
RRO: 104679852(BMPR1B)
RBB: 108531867(BMPR1B)
TFN: 117085690(BMPR1B)
PTEH: 111527133(BMPR1B)
CJC: 100397724(BMPR1B)
SBQ: 101046738(BMPR1B)
CSYR: 103256175(BMPR1B)
MMUR: 105870796(BMPR1B)
LCAT: 123627264(BMPR1B)
OGA: 100954342(BMPR1B)
MMU: 12167(Bmpr1b)
MCAL: 110290823(Bmpr1b)
MPAH: 110319737(Bmpr1b)
RNO: 310914(Bmpr1b)
MCOC: 116093866(Bmpr1b)
MUN: 110561307(Bmpr1b)
CGE: 100774629
MAUA: 101835618(Bmpr1b)
PLEU: 114681722(Bmpr1b)
MORG: 121446008(Bmpr1b)
AAMP: 119800949(Bmpr1b)
NGI: 103728063(Bmpr1b)
HGL: 101710196(Bmpr1b)
CPOC: 100732675(Bmpr1b)
CCAN: 109703066(Bmpr1b)
DORD: 105995850(Bmpr1b)
DSP: 122127136(Bmpr1b)
NCAR: 124994650
OCU: 100351275(BMPR1B)
OPI: 101522569(BMPR1B)
TUP: 102496847
CFA: 478484(BMPR1B)
CLUD: 112645135(BMPR1B)
VVP: 112932648(BMPR1B)
VLG: 121493624(BMPR1B)
AML: 100467049(BMPR1B)
UMR: 103677908(BMPR1B)
UAH: 113263130(BMPR1B)
UAR: 123788609(BMPR1B)
ELK: 111155171
LLV: 125093190
MPUF: 101680784(BMPR1B)
ORO: 101373181(BMPR1B)
EJU: 114220098(BMPR1B)
ZCA: 113925802(BMPR1B)
MLX: 118010315(BMPR1B)
FCA: 101082489(BMPR1B)
PYU: 121032188(BMPR1B)
PBG: 122478431(BMPR1B)
PTG: 102968798(BMPR1B)
PPAD: 109275645(BMPR1B)
AJU: 106983784(BMPR1B)
HHV: 120237845(BMPR1B)
BTA: 407128(BMPR1B)
BOM: 102284193(BMPR1B)
BIU: 109560330(BMPR1B)
BBUB: 102399524(BMPR1B)
CHX: 100861211(BMPR1B)
OAS: 443454(BMPR1B)
ODA: 120861921(BMPR1B)
CCAD: 122422280(BMPR1B)
SSC: 396691(BMPR1B)
CFR: 102511519(BMPR1B)
CBAI: 105067883(BMPR1B)
CDK: 105089530(BMPR1B)
VPC: 102531544(BMPR1B)
BACU: 103017850(BMPR1B)
LVE: 103077119(BMPR1B)
OOR: 101287667(BMPR1B)
DLE: 111179080(BMPR1B)
PCAD: 102983663(BMPR1B)
PSIU: 116754357(BMPR1B)
ECB: 100053554(BMPR1B)
EPZ: 103557055(BMPR1B)
EAI: 106826733(BMPR1B)
MYB: 102255240(BMPR1B)
MYD: 102764015(BMPR1B)
MMYO: 118671609(BMPR1B)
MLF: 102427396(BMPR1B)
MNA: 107531931(BMPR1B)
PKL: 118703859(BMPR1B)
HAI: 109385323(BMPR1B)
DRO: 112317823(BMPR1B)
SHON: 118987039(BMPR1B)
AJM: 119045406(BMPR1B)
PDIC: 114493021(BMPR1B)
PHAS: 123806904(BMPR1B)
MMF: 118631469(BMPR1B)
RFQ: 117022555(BMPR1B)
PALE: 102896177(BMPR1B)
PGIG: 120588330(BMPR1B)
PVP: 105289544(BMPR1B)
RAY: 107510637(BMPR1B)
MJV: 108399139(BMPR1B)
TOD: 119261364(BMPR1B)
SARA: 101539626(BMPR1B)
LAV: 100660194(BMPR1B)
TMU: 101344166
DNM: 101423411(BMPR1B)
MDO: 100016370(BMPR1B)
GAS: 123253139(BMPR1B)
SHR: 100920492(BMPR1B)
OAA: 100086574(BMPR1B)
GGA: 396030(BMPR1B)
PCOC: 116231277(BMPR1B)
MGP: 100543302(BMPR1B)
CJO: 107313618(BMPR1B)
NMEL: 110398680(BMPR1B)
APLA: 101794439(BMPR1B)
ACYG: 106041244(BMPR1B)
AFUL: 116488894(BMPR1B)
TGU: 100218713(BMPR1B)
LSR: 110481569(BMPR1B)
SCAN: 103826038(BMPR1B)
PMOA: 120502826(BMPR1B)
OTC: 121346562(BMPR1B)
PRUF: 121362603(BMPR1B)
GFR: 102045388(BMPR1B)
FAB: 101818178(BMPR1B)
PHI: 102103410(BMPR1B)
PMAJ: 107203490(BMPR1B)
CCAE: 111929421(BMPR1B)
CCW: 104697196(BMPR1B)
CBRC: 103622907(BMPR1B)
ETL: 114064806(BMPR1B)
ZAB: 102071053(BMPR1B)
FPG: 101913989(BMPR1B)
FCH: 102054291(BMPR1B)
CLV: 102092756(BMPR1B)
EGZ: 104122617(BMPR1B)
NNI: 104021195(BMPR1B)
PLET: 104620495(BMPR1B)
PCRI: 104039015(BMPR1B)
ACUN: 113479504(BMPR1B)
TALA: 104366978(BMPR1B)
PADL: 103919510(BMPR1B)
ACHC: 115345016(BMPR1B)
HALD: 104318627(BMPR1B)
CCRI: 104158928(BMPR1B)
CSTI: 104551089(BMPR1B)
EHS: 104511681(BMPR1B)
CMAC: 104484651
FGA: 104084046(BMPR1B)
GSTE: 104262135
LDI: 104341222
MNB: 103771819(BMPR1B)
OHA: 104331640(BMPR1B)
AAM: 106491882(BMPR1B)
AROW: 112974829(BMPR1B)
NPD: 112949366(BMPR1B)
DNE: 112984519(BMPR1B)
ASN: 102369865(BMPR1B)
AMJ: 102561072(BMPR1B)
CPOO: 109322301(BMPR1B)
GGN: 109304034(BMPR1B)
PSS: 102449724(BMPR1B)
CMY: 102945112(BMPR1B)
CPIC: 101946330(BMPR1B)
TST: 117878186(BMPR1B)
MRV: 120375539 120406293(BMPR1B)
ACS: 100553122(bmpr1b)
PVT: 110081721(BMPR1B)
SUND: 121930750(BMPR1B)
PBI: 103058301
PMUR: 107294782(BMPR1B)
TSR: 106550986(BMPR1B)
PGUT: 117678965(BMPR1B)
VKO: 123023062(BMPR1B)
PMUA: 114603946(BMPR1B)
ZVI: 118083897(BMPR1B)
GJA: 107116711(BMPR1B)
STOW: 125439933(BMPR1B)
XLA: 108706748(bmpr1b.S) 108710900(bmpr1b.L)
XTR: 780089(bmpr1b)
NPR: 108785433(BMPR1B)
RTEM: 120917009(BMPR1B)
BBUF: 120989824(BMPR1B)
BGAR: 122926230(BMPR1B)
DRE: 100149664(bmpr1bb) 30742(bmpr1ba)
PPRM: 120482687(bmpr1bb) 120487994(bmpr1ba)
MAMB: 125262547(bmpr1bb) 125267240(bmpr1ba)
IPU: 108277027(bmpr1bb)
PHYP: 113544873(bmpr1b)
SMEO: 124393661(bmpr1bb)
TFD: 113638483(bmpr1bb)
AMEX: 111195008(bmpr1b)
EEE: 113567944 113573320(bmpr1b)
TRU: 101061264 101075765(bmpr1b)
LCO: 104920273(bmpr1b) 104924706
NCC: 104950677(bmpr1b)
CGOB: 115013755(bmpr1b) 115016468
ELY: 117253034(bmpr1ba) 117269956(bmpr1bb)
EFO: 125890542(bmpr1ba) 125905634(bmpr1bb)
PLEP: 121937697 121943931(bmpr1ba)
SLUC: 116035056(bmpr1bb) 116056716(bmpr1ba)
ECRA: 117944374(bmpr1ba) 117959665(bmpr1bb)
PFLV: 114555306(bmpr1b) 114570926
GAT: 120831025(bmpr1ba) 120831885(bmpr1bb)
PPUG: 119225477(bmpr1ba) 119227017(bmpr1bb)
MSAM: 119891347(bmpr1ba) 119914293(bmpr1bb)
CUD: 121510308(bmpr1ba) 121525612(bmpr1bb)
ALAT: 119019450(bmpr1ba) 119029421(bmpr1bb)
ONL: 100690021(bmpr1b) 100697982
OAU: 116311877(bmpr1ba) 116322454(bmpr1bb)
OLA: 101163987 101171086(bmpr1b)
OML: 112148815(bmpr1ba) 112163021(bmpr1bb)
XMA: 102226015 102230081(bmpr1b)
XCO: 114149477 114154918(bmpr1b)
XHE: 116724855 116730122(bmpr1b)
PRET: 103470230(bmpr1b) 103473770
GAF: 122819506(bmpr1bb) 122828126(bmpr1ba)
CVG: 107084462(bmpr1b) 107088457
CTUL: 119791017(bmpr1bb) 119797157(bmpr1ba)
GMU: 124873081(bmpr1bb) 124877955(bmpr1ba)
NFU: 107373829 107394018(bmpr1b)
KMR: 108234542(bmpr1ba) 108247544(bmpr1bb)
ALIM: 106514446 106533827(bmpr1b)
NWH: 119413327(bmpr1ba) 119424607(bmpr1bb)
AOCE: 111574921 111576466(bmpr1b)
MCEP: 124996523(bmpr1bb) 125012654(bmpr1ba)
CSEM: 103390150 103398158(bmpr1b)
POV: 109626287 109638193(bmpr1b)
SSEN: 122758163(bmpr1bb) 122769449(bmpr1ba)
HHIP: 117767605(bmpr1ba) 117771516(bmpr1bb)
HSP: 118115444(bmpr1ba) 118125680(bmpr1bb)
LCF: 108878299(bmpr1b) 108879878
SDU: 111230879(bmpr1b) 111237790
XGL: 120805309(bmpr1ba) 120806394(bmpr1bb)
HCQ: 109526066 109526258(bmpr1b)
MALB: 109961609(bmpr1b) 109970815
BSPL: 114862607(bmpr1ba) 114866477(bmpr1bb)
OMY: 110522929(bmpr1bb) 110525233(bmpr1ba) 110536815
OGO: 123999666 124034656(bmpr1ba) 124048766(bmpr1bb)
SALP: 111961436
SNH: 120026464(bmpr1bb) 120041793(bmpr1ba) 120044235
ELS: 105014580(bmpr1b) 105025159
PKI: 111842039 111856572(bmpr1b)
AANG: 118206920(bmpr1ba) 118213440
LOC: 102686806(bmpr1b)
PSPA: 121298854
LCM: 102364169(BMPR1B)
CMK: 103184492(bmpr1ba)
BFO: 118412357
BBEL: 109466679
SCLV: 120347291
SPU: 592872
APLC: 110978597
SKO: 100303460(bmpR1)
DME: Dmel_CG14026(tkv)
DER: 6540645
DSE: 6613461
DSI: Dsimw501_GD22659(Dsim_GD22659)
DAN: 6498327
DSR: 110187397
DPO: 4817227
DPE: 6588982
DMN: 108162467
DWI: 6646565
DGR: 6566681
DAZ: 108616910
DNV: 108655109
DHE: 111599898
DVI: 6636326
CCAT: 101458302
BOD: 106616764
MDE: 101900564
SCAC: 106089634
LCQ: 111684178
LSQ: 119609624
HIS: 119650837
ACOZ: 120958566
AARA: 120899646
ASTE: 118510850
CNS: 116337061
BCOO: 119075322
AME: 408442
ACER: 107994622
ALAB: 122711353
BIM: 100747692
BBIF: 117209979
BVK: 117243049
BVAN: 117160822
BTER: 105665609
BPYO: 122575161
CCAL: 108627633
OBB: 114879670
MGEN: 117226010
NMEA: 116427176
CGIG: 122403101
SOC: 105194209
MPHA: 105838849
AEC: 105143402
ACEP: 105627533
PBAR: 105431245
VEM: 105563224
HST: 105189577
DQU: 106749199
CFO: 105259212
FEX: 115239944
LHU: 105677089
PGC: 109853566
OBO: 105283439
PCF: 106786117
PFUC: 122516506
VPS: 122632314
NVI: 100116851
CSOL: 105364340
MDL: 103580360
CGLO: 123269484
FAS: 105263163
DAM: 107039591
LHT: 122503565
TCA: 659260(thickveins)
ATD: 109594648
CSET: 123317594
NVL: 108557405
APLN: 108734624
PPYR: 116177804
OTU: 111413406
BMOR: 101741200
BMAN: 114250588
MSEX: 115444194
BANY: 112044074
PPOT: 106105178
PXU: 106125618
PRAP: 110999119
HAW: 110379864
HZE: 124638710
TNL: 113503669
SLIU: 111354106
OFU: 114350021
API: 100167815
DNX: 107170416
AGS: 114133078
RMD: 113553055
CLEC: 106670988
HHAL: 106682650
NLU: 111054912
FOC: 113203102
TPAL: 117650319
ZNE: 110830227
CSEC: 111869030
FCD: 110858668
DMK: 116936600
PVM: 113802620
PJA: 122244057
PCHN: 125025212
HAME: 121877380
PCLA: 123760134
HAZT: 108671166
DSV: 119436852
RSAN: 119396665
RMP: 119161301
CSCU: 111631396
PTEP: 107445266
SDM: 118184832
CEL: CELE_C32D5.2(sma-6)
CBR: CBG_02627(Cbr-sma-6)
BMY: BM_BM2507(Bma-sma-6)
TSP: Tsp_04000
PCAN: 112557043
BGT: 106071866
GAE: 121380208
HRF: 124132568
HRJ: 124279594
CRG: 105332635
MYI: 110451209
PMAX: 117330899
MMER: 123564025
OBI: 106873837
OSN: 115213859
LAK: 106160415
NVE: 5513627
EPA: 110232951
ATEN: 116303934
PDAM: 113666029
SPIS: 111337202
DGT: 114523050
XEN: 124452398
 » show all
Reference
PMID:9178898
  Authors
Ide H, Katoh M, Sasaki H, Yoshida T, Aoki K, Nawa Y, Osada Y, Sugimura T, Terada M
  Title
Cloning of human bone morphogenetic protein type IB receptor (BMPR-IB) and its expression in prostate cancer in comparison with other BMPRs.
  Journal
Oncogene 14:1377-82 (1997)
DOI:10.1038/sj.onc.1200964
  Sequence
[hsa:658]
Reference
  Authors
Graul-Neumann LM, Deichsel A, Wille U, Kakar N, Koll R, Bassir C, Ahmad J, Cormier-Daire V, Mundlos S, Kubisch C, Borck G, Klopocki E, Mueller TD, Doelken SC, Seemann P
  Title
Homozygous missense and nonsense mutations in BMPR1B cause acromesomelic chondrodysplasia-type Grebe.
  Journal
Eur J Hum Genet 22:726-33 (2014)
DOI:10.1038/ejhg.2013.222
  Sequence
[hsa:658]

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