KEGG   ORTHOLOGY: K13700Help
Entry
K13700                      KO                                     

Name
ABHD6
Definition
abhydrolase domain-containing protein 6 [EC:3.1.1.23]
Pathway
ko04723  Retrograde endocannabinoid signaling
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Nervous system
   04723 Retrograde endocannabinoid signaling
    K13700  ABHD6; abhydrolase domain-containing protein 6
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.23  acylglycerol lipase
     K13700  ABHD6; abhydrolase domain-containing protein 6
Peptidases [BR:ko01002]
 Serine Peptidases
  Family S33
   K13700  ABHD6; abhydrolase domain-containing protein 6
BRITE hierarchy
Other DBs
RN: R01352
GO: 0047372
Genes
HSA: 57406(ABHD6)
PTR: 470830(ABHD6)
PPS: 100991016(ABHD6)
GGO: 101133371(ABHD6)
PON: 100433718(ABHD6)
NLE: 100603829(ABHD6)
MCC: 702384(ABHD6)
MCF: 101865192(ABHD6)
CSAB: 103227807(ABHD6)
RRO: 104660191(ABHD6)
RBB: 108543611(ABHD6)
CJC: 100399741(ABHD6)
SBQ: 101029501(ABHD6)
MMU: 66082(Abhd6)
RNO: 305795(Abhd6)
CGE: 100769391(Abhd6)
NGI: 103740533(Abhd6)
HGL: 101709119(Abhd6)
CCAN: 109697257(Abhd6)
OCU: 100355792(ABHD6)
TUP: 102495614(ABHD6)
CFA: 484712(ABHD6)
UMR: 103674201(ABHD6)
ORO: 101384286(ABHD6)
FCA: 101099621(ABHD6)
PTG: 102951092(ABHD6)
AJU: 106968842(ABHD6)
BTA: 505283(ABHD6)
BOM: 102264967(ABHD6)
BIU: 109576324(ABHD6)
PHD: 102316504(ABHD6)
CHX: 102186912(ABHD6)
OAS: 101122635(ABHD6)
SSC: 100515411(ABHD6)
CFR: 102514395(ABHD6)
CDK: 105089804(ABHD6)
BACU: 103019625(ABHD6)
LVE: 103084100(ABHD6)
OOR: 101286268(ABHD6)
ECB: 100057821(ABHD6)
EPZ: 103550624(ABHD6)
EAI: 106848671(ABHD6)
MYB: 102256495(ABHD6)
MYD: 102763677(ABHD6)
HAI: 109388234(ABHD6)
RSS: 109443595(ABHD6)
PALE: 102885597(ABHD6)
LAV: 100654589(ABHD6)
TMU: 101341187
MDO: 100014368(ABHD6)
SHR: 100922543(ABHD6)
OAA: 100093261(ABHD6)
GGA: 416009(ABHD6)
MGP: 100549431(ABHD6)
CJO: 107320004(ABHD6)
APLA: 101797444(ABHD6)
ACYG: 106038037(ABHD6)
TGU: 100223089(ABHD6)
GFR: 102038736(ABHD6)
FAB: 101814682(ABHD6)
PHI: 102113368(ABHD6)
PMAJ: 107210494(ABHD6)
CCW: 104683277(ABHD6)
FPG: 101917545(ABHD6)
FCH: 102056134(ABHD6)
CLV: 102090678(ABHD6)
EGZ: 104126718(ABHD6)
AAM: 106485081(ABHD6)
ASN: 102369326(ABHD6)
AMJ: 102573436(ABHD6)
PSS: 102452924(ABHD6)
CMY: 102947149(ABHD6)
CPIC: 101931833(ABHD6)
PBI: 103066569(ABHD6) 103066701
XLA: 380544(abhd6.S) 444738(abhd6.L)
XTR: 100145783(abhd6)
NPR: 108791855(ABHD6)
DRE: 799085(abhd6a)
IPU: 108254751(abhd6) 108275644
AMEX: 103028342 103035021(abhd6)
TRU: 101061228 101075359(abhd6)
LCO: 104935829 104940345(abhd6)
MZE: 101466698 101485424(abhd6)
OLA: 101167454 101175545(abhd6)
PRET: 103464284 103467549(abhd6)
NFU: 107391074(abhd6)
CSEM: 103385492 103386668(abhd6)
LCF: 108874798(abhd6) 108889494
HCQ: 109510343(abhd6) 109528715
BPEC: 110157964(abhd6)
SASA: 100195326(abhd6) 106566659
ELS: 105013312(abhd6) 105013987
SFM: 108929761(abhd6)
LCM: 102364120(ABHD6)
CMK: 103190038(abhd6)
APLC: 110986474
SKO: 102807223
CRG: 105320493
MYI: 110445921
EPA: 110250920
ADF: 107336014
AQU: 100634628
SPAR: SPRG_09302
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Marrs WR, Blankman JL, Horne EA, Thomazeau A, Lin YH, Coy J, Bodor AL, Muccioli GG, Hu SS, Woodruff G, Fung S, Lafourcade M, Alexander JP, Long JZ, Li W, Xu C, Moller T, Mackie K, Manzoni OJ, Cravatt BF, Stella N
  Title
The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.
  Journal
Nat Neurosci 13:951-7 (2010)
DOI:10.1038/nn.2601
  Sequence
[mmu:66082]
Reference
  Authors
Blankman JL, Simon GM, Cravatt BF
  Title
A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol.
  Journal
Chem Biol 14:1347-56 (2007)
DOI:10.1016/j.chembiol.2007.11.006
  Sequence
[mmu:66082]

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