KEGG   ORTHOLOGY: K14039
Entry
K14039            Tight     KO                                     

Name
E1.14.99.37
Definition
taxadiene 5alpha-hydroxylase [EC:1.14.99.37]
Pathway
ko00904  Diterpenoid biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00904 Diterpenoid biosynthesis
    K14039  E1.14.99.37; taxadiene 5alpha-hydroxylase
Other DBs
RN: R06306
GO: 0050604
Genes
AG: AAQ56240
Reference
  Authors
Jennewein S, Long RM, Williams RM, Croteau R
  Title
Cytochrome p450 taxadiene 5alpha-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis.
  Journal
Chem Biol 11:379-87 (2004)
DOI:10.1016/j.chembiol.2004.02.022
  Sequence

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