KEGG   ORTHOLOGY: K14152Help
Entry
K14152                      KO                                     

Name
HIS4
Definition
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:3.6.1.31 3.5.4.19 1.1.1.23]
Pathway
ko00340  Histidine metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko01230  Biosynthesis of amino acids
Module
M00026  Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00340 Histidine metabolism
    K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.23  histidinol dehydrogenase
     K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.19  phosphoribosyl-AMP cyclohydrolase
     K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
  3.6  Acting on acid anhydrides
   3.6.1  In phosphorus-containing anhydrides
    3.6.1.31  phosphoribosyl-ATP diphosphatase
     K14152  HIS4; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase
BRITE hierarchy
Other DBs
RN: R01158 R01163 R03012 R04035 R04037
COG: COG0140 COG0139 COG0141
GO: 0004636 0004635 0004399
Genes
TNG: GSTEN00037599G001
PDAM: 113676644
SPIS: 111332294
QSU: 111990103 112019153
SCE: YCL030C(HIS4)
AGO: AGOS_AFR703W
ERC: Ecym_1051
KLA: KLLA0_C01452g
KMX: KLMA_10065(HIS4)
LTH: KLTH0F01430g
NCS: NCAS_0B08820(NCAS0B08820)
NDI: NDAI_0A00450(NDAI0A00450)
TPF: TPHA_0E03690(TPHA0E03690)
TDL: TDEL_0C06570(TDEL0C06570)
KAF: KAFR_0D00420(KAFR0D00420)
PIC: PICST_89228(HIS2)
SPAA: SPAPADRAFT_141809(HIS2)
CAL: CAALFM_C400140CA(HIS4)
CDU: CD36_40210(HIS4)
SLB: AWJ20_2549(HIS4)
NCR: NCU03139(his-3)
NTE: NEUTE1DRAFT150173(NEUTE1DRAFT_150173)
MGR: MGG_01309
SSCK: SPSK_01021
MAW: MAC_06198
MAJ: MAA_00713
CMT: CCM_05425
BFU: BCIN_05g05260(Bchis4)
MBE: MBM_03520
ANI: AN0797.2
ANG: ANI_1_1704014(An01g12570)
ABE: ARB_00034
TVE: TRV_06267
PTE: PTT_17572
SPO: SPBC1711.13(his2)
CNE: CND06120
CNB: CNBD0280
ABP: AGABI1DRAFT72979(AGABI1DRAFT_72979)
ABV: AGABI2DRAFT184772(AGABI2DRAFT_184772)
MGL: MGL_2613
SPAR: SPRG_13327
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7049842
  Authors
Donahue TF, Farabaugh PJ, Fink GR
  Title
The nucleotide sequence of the HIS4 region of yeast.
  Journal
Gene 18:47-59 (1982)
DOI:10.1016/0378-1119(82)90055-5
  Sequence
[sce:YCL030C]

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