KEGG   ORTHOLOGY: K14216
Entry
K14216                      KO                                     

Name
OAS
Definition
2'-5'-oligoadenylate synthetase [EC:2.7.7.84]
Pathway
ko04621  NOD-like receptor signaling pathway
ko05160  Hepatitis C
ko05162  Measles
ko05164  Influenza A
ko05168  Herpes simplex virus 1 infection
ko05169  Epstein-Barr virus infection
ko05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K14216  OAS; 2'-5'-oligoadenylate synthetase
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    K14216  OAS; 2'-5'-oligoadenylate synthetase
   05171 Coronavirus disease - COVID-19
    K14216  OAS; 2'-5'-oligoadenylate synthetase
   05164 Influenza A
    K14216  OAS; 2'-5'-oligoadenylate synthetase
   05162 Measles
    K14216  OAS; 2'-5'-oligoadenylate synthetase
   05168 Herpes simplex virus 1 infection
    K14216  OAS; 2'-5'-oligoadenylate synthetase
   05169 Epstein-Barr virus infection
    K14216  OAS; 2'-5'-oligoadenylate synthetase
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.84  2'-5' oligoadenylate synthase
     K14216  OAS; 2'-5'-oligoadenylate synthetase
Other DBs
RN: R10909 R10910
Genes
HSA: 4938(OAS1) 4939(OAS2) 4940(OAS3)
PTR: 452267(OAS3) 739129(OAS1) 739230(OAS2)
PPS: 100970211(OAS3) 100993699(OAS1) 103783986(OAS2)
GGO: 101128307(OAS1) 101128904(OAS2) 101129249(OAS3)
PON: 100172992(OAS1) 100443561(OAS3) 100444286(OAS2)
NLE: 100587554(OAS1) 100587890(OAS3) 100588209(OAS2)
MCC: 712265(OAS1) 712342(OAS3) 712401(OAS2)
MCF: 102131636(OAS1) 102132016(OAS3) 102132392(OAS2)
CSAB: 103239154(OAS1) 103239155(OAS3) 103239156(OAS2)
RRO: 104666641(OAS1) 104666642(OAS3) 104666645(OAS2)
RBB: 108540456(OAS3) 108540457(OAS1) 108540462(OAS2)
CJC: 100385368(OAS1) 100392459(OAS3) 103795420(OAS2)
SBQ: 101043239(OAS2) 101043563(OAS3) 101043879(OAS1)
MMU: 23960(Oas1g) 23961(Oas1b) 246727(Oas3) 246728(Oas2) 246730(Oas1a)
MCAL: 110293989 110293990 110293991 110293992 110293993 110293994 110294376 110294589(Oas3) 110295017(Oas2)
MPAH: 110313134(Oas2) 110313135(Oas3) 110313137 110339082 110339083 110339085 110339086 110339087 110339088
RNO: 100910735(Oas1g) 192281(Oas1a) 246268(Oas1b) 304507(Oas1i) 363938(Oas2) 494202(Oas3)
MUN: 110546395(Oas1) 110546404(Oas3) 110546405 110546406
CGE: 100761048 100767905 100768468 100768763 100769335 100769624 100769916(Oas3) 100770794 113831143(Oas2)
NGI: 103745552 103745585 103745586(Oas3) 103745587
HGL: 101698818(Oas2) 101699903(Oas1)
CCAN: 109675879 109675880 109681969 109681970
OCU: 100340530(OAS3) 100340787(OAS2) 108178670(OAS1)
TUP: 102495865(OAS2) 106735200(OAS1)
CFA: 477490(OAS3) 608778(OAS1) 611051(OAS2)
VVP: 112935202(OAS1) 112935211(OAS3)
AML: 100468112(OAS2) 100469118(OAS1) 100469368(OAS3)
UMR: 103661196(OAS1) 103661197(OAS2) 103661290(OAS3)
UAH: 113266813(OAS3) 113266985
ORO: 101369458(OAS2) 101373749(OAS1) 101374040(OAS3)
ELK: 111156451 111156463 111156464
FCA: 101087875(OAS1) 101088116(OAS3) 102902426(OAS2)
PTG: 102952232(OAS3) 107179395(OAS2)
PPAD: 109277626(OAS1) 109277795(OAS3)
AJU: 106982083 113595144
BTA: 347699(OAS1X) 519922(OAS1Z) 529660(OAS2) 654488(OAS1Y)
BOM: 102283231 102283513 102283796(OAS2)
BIU: 109570926 109571283(OAS2) 109571284
BBUB: 102395010 102407094 102407627(OAS1) 102408391(OAS2)
CHX: 102186893(OAS2) 102190983
OAS: 101109915 101110181 101112122 105602911 114108712 114118858
SSC: 397570(OAS1) 595128(OAS2)
CFR: 102524147(OAS1)
CDK: 105101979(OAS1)
BACU: 102999657 103002522(OAS2) 103002794 103003537(OAS1)
LVE: 103087433(OAS1) 103087703(OAS2)
OOR: 101277868(OAS2) 101289192
DLE: 111162647
PCAD: 102995339(OAS2) 102995791(OAS1) 102996067
ECB: 100034147(OAS1) 791225(OAS3) 791250(OAS2)
EPZ: 103542327(OAS2) 103543308(OAS3) 103557130
EAI: 106842212 106842249(OAS1)
MYB: 102247108(OAS1) 102251057(OAS2) 102258838
MYD: 102756142(OAS3) 102756409(OAS2) 102759968(OAS1)
MNA: 107529575 107529617 107545518
HAI: 109382229 109382257
DRO: 112310467(OAS3) 112310771 112317826
PALE: 102879074(OAS1) 102879322(OAS3) 102889470(OAS2)
RAY: 107513228 107513273(OAS1)
MJV: 108384390 108384393(OAS2) 108387381
LAV: 100659469(OAS2) 104846792(OAS3) 104846793(OAS1)
TMU: 101344040 101344304 101347429
MDO: 100028774(OAS3) 100028841 100028903(OAS1)
SHR: 100928002(OAS3) 100928264 105749342
PCW: 110202068 110202070 110202095(OAS2)
AMJ: 106737542(OAS1)
PSS: 102447754 102448391
CMY: 102937233(OAS3)
CPIC: 101945210
ACS: 100562806(oas1)
PVT: 110082886
PBI: 103053194
PMUR: 107285479 107297389
TSR: 106554335
PMUA: 114586818
GJA: 107122904 107125898
LCM: 102355743
CMK: 103184093
RTP: 109931758 109931761
BFO: 118415180 118421963 118421966
APLC: 110976512 110982654 110982655 110982656 110982668 110982703
SKO: 102802564
FCD: 110850527
LGI: LOTGIDRAFT_161508 LOTGIDRAFT_233290
PCAN: 112559330 112559331 112560500 112576994 112576995 112576996 112576997
CRG: 105337972 105348571
LAK: 106154994 106159596 106172491
NVE: 5515274
ADF: 107334717 107334718 107357250
AMIL: 114959348 114959349 114959351 114973781
DGT: 114526963 114529882 114529883 114529884 114529910 114529911 114529977 114535094 114535102 114535105 114535124
AQU: 105316703 109580198 109581478
 » show all
Reference
PMID:2416561
  Authors
Benech P, Mory Y, Revel M, Chebath J
  Title
Structure of two forms of the interferon-induced (2'-5') oligo A synthetase of human cells based on cDNAs and gene sequences.
  Journal
EMBO J 4:2249-56 (1985)
DOI:10.1002/j.1460-2075.1985.tb03922.x
  Sequence
[hsa:4938]
Reference
PMID:1577824
  Authors
Marie I, Hovanessian AG
  Title
The 69-kDa 2-5A synthetase is composed of two homologous and adjacent functional domains.
  Journal
J Biol Chem 267:9933-9 (1992)
  Sequence
[hsa:4939]
Reference
  Authors
Ito M, Shichijo S, Tsuda N, Ochi M, Harashima N, Saito N, Itoh K
  Title
Molecular basis of T cell-mediated recognition of pancreatic cancer cells.
  Journal
Cancer Res 61:2038-46 (2001)
  Sequence
[hsa:4940]

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (14)   
   KEGG PATHWAY (14)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
   KEGG RCLASS (1)   
Gene (510)   
   KEGG GENES (272)   
   KEGG MGENES (10)   
   RefGene (214)   
   OC (14)   
Literature (3)   
   PubMed (3)   
All databases (533)   

Download RDF
DBGET integrated database retrieval system