KEGG   ORTHOLOGY: K14369
Entry
K14369                      KO                                     
Symbol
eryG
Name
erythromycin 3''-O-methyltransferase [EC:2.1.1.254]
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00774  Erythromycin biosynthesis, propanoyl-CoA + methylmalonyl-CoA => deoxyerythronolide B => erythromycin A/B
Reaction
R05520  S-adenosyl-L-methionine:erythromycin-C 3''-O-methyltransferase
R05532  S-adenosyl-L-methionine:erythromycin-D 3''-O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K14369  eryG; erythromycin 3''-O-methyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K14369  eryG; erythromycin 3''-O-methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.254  erythromycin 3''-O-methyltransferase
     K14369  eryG; erythromycin 3''-O-methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Methylase
   K14369  eryG; erythromycin 3''-O-methyltransferase
Genes
AER: AERYTH_15890
SEN: SACE_0728(eryG)
Reference
PMID:1840640
  Authors
Haydock SF, Dowson JA, Dhillon N, Roberts GA, Cortes J, Leadlay PF
  Title
Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases.
  Journal
Mol Gen Genet 230:120-8 (1991)
DOI:10.1007/BF00290659
  Sequence
[sen:SACE_0728]

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
   KEGG RCLASS (2)   
Gene (3)   
   KEGG GENES (2)   
   OC (1)   
Literature (1)   
   PubMed (1)   
All databases (19)   

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