KEGG   ORTHOLOGY: K14396Help
Entry
K14396                      KO                                     

Name
PABPN1, PABP2
Definition
polyadenylate-binding protein 2
Pathway
ko03015  mRNA surveillance pathway
ko05164  Influenza A
Disease
H00704  Oculopharyngeal muscular dystrophy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    K14396  PABPN1, PABP2; polyadenylate-binding protein 2
 09160 Human Diseases
  09172 Infectious disease: viral
   05164 Influenza A
    K14396  PABPN1, PABP2; polyadenylate-binding protein 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K14396  PABPN1, PABP2; polyadenylate-binding protein 2
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Other transport factors
     K14396  PABPN1, PABP2; polyadenylate-binding protein 2
BRITE hierarchy
Genes
HSA: 100529063(BCL2L2-PABPN1) 390748(PABPN1L) 8106(PABPN1)
PTR: 100612015(PABPN1L) 452797
PPS: 100981014(PABPN1) 100991758(PABPN1L)
GGO: 101134783 101147934(PABPN1L)
PON: 100442963 100457652(PABPN1L)
MCC: 713572 721624(PABPN1L)
MCF: 101867156 102123787(PABPN1L)
CSAB: 103231469(PABPN1) 103232947 103233463(PABPN1L)
RRO: 104653614 104656047(PABPN1L)
RBB: 108520280(PABPN1L) 108520669 108523566 108525626
CJC: 100389399(PABPN1L) 100396934(PABPN1)
SBQ: 101033235 101046378(PABPN1L)
MMU: 382035(Pabpn1l) 54196(Pabpn1)
MCAL: 110300697(Pabpn1l) 110309062(Pabpn1)
MPAH: 110325304(Pabpn1) 110337683(Pabpn1l)
RNO: 116697(Pabpn1) 307920(Pabpn1l)
MUN: 110545201(Pabpn1l) 110550029(Pabpn1)
CGE: 100765187(Pabpn1l) 100771019
NGI: 103739461(Pabpn1) 103740002(Pabpn1l)
HGL: 101710651(Pabpn1l) 101714601(Pabpn1)
CCAN: 109692767(Pabpn1l) 109697773(Pabpn1)
OCU: 100341393 100345355(PABPN1)
TUP: 102481490(PABPN1)
CFA: 100170671(PABPN1) 608851(PABPN1L)
VVP: 112924548(PABPN1L) 112926513
AML: 100465298(PABPN1) 100479030(PABPN1L)
UMR: 103673960(PABPN1L) 103681044(PABPN1)
UAH: 113246081(PABPN1) 113251691(PABPN1L)
ORO: 101362635(PABPN1) 101379845(PABPN1L)
ELK: 111160801
FCA: 101092223(PABPN1L) 102901720(PABPN1)
PTG: 102971101(PABPN1) 102972466(PABPN1L)
PPAD: 109245726(PABPN1L) 109255027
AJU: 106973499(PABPN1L)
BTA: 282298(PABPN1) 617429(PABPN1L)
BOM: 102275859(PABPN1) 102280384(PABPN1L)
BIU: 109564800(PABPN1) 109573001(PABPN1L) 109575992
BBUB: 102400909(PABPN1) 102405316(PABPN1L)
CHX: 102172629(PABPN1) 102190809(PABPN1L)
OAS: 101108854(PABPN1L) 105608566
SSC: 100155260(PABPN1) 100525398(PABPN1L)
CFR: 102515209(PABPN1)
CDK: 105096986(PABPN1) 105104691(PABPN1L)
BACU: 103002758 103006844(PABPN1L) 103011539(PABPN1) 103018458
LVE: 103069240(PABPN1L) 103069427 103088959(PABPN1)
OOR: 101273046(PABPN1L) 101278940(PABPN1)
DLE: 111164107 111179339(PABPN1L)
ECB: 100051357(PABPN1L) 102149994(PABPN1)
EPZ: 103556756(PABPN1)
EAI: 106828193(PABPN1L) 106840641
MYB: 102245535 102251980(PABPN1)
MYD: 102755816(PABPN1) 102759017(PABPN1L)
MNA: 107531704(PABPN1) 107543395(PABPN1L)
HAI: 109389177(PABPN1L) 109393643(PABPN1)
DRO: 112300571(PABPN1L) 112301344
PALE: 102887735(PABPN1L)
RAY: 107497982(PABPN1) 107502356(PABPN1L)
MJV: 108385615(PABPN1L) 108400025(PABPN1)
LAV: 100673314(PABPN1L) 104846994(PABPN1)
MDO: 100024631(PABPN1) 100026268(PABPN1L)
SHR: 100913313 100934313(PABPN1L) 111719772(PABPN1)
PCW: 110193030(PABPN1) 110210485(PABPN1L)
OAA: 100081310(PABPN1L) 100091694
GGA: 769028(PABPN1L)
MGP: 104913066(PABPN1L)
CJO: 107319530(PABPN1L)
NMEL: 110404193(PABPN1L)
APLA: 101791322(PABPN1L)
ACYG: 106046521(PABPN1L)
LSR: 110468801(PABPN1L) 110481922(PABPN1)
SCAN: 103816889(PABPN1L) 115484225(PABPN1)
GFR: 102037386(PABPN1L)
FAB: 101817743(PABPN1L)
PHI: 102101485(PABPN1L)
PMAJ: 107209617(PABPN1L)
CCAE: 111934401(PABPN1L) 111942994 111943552
CCW: 104691930(PABPN1L)
ETL: 114060551(PABPN1L)
FPG: 101923639(PABPN1L)
FCH: 102052867(PABPN1L)
CLV: 102096608(PABPN1L)
EGZ: 104127044(PABPN1L)
NNI: 104022824 104023638(PABPN1L)
ACUN: 113484602(PABPN1L)
PADL: 103919465(PABPN1L)
ASN: 102376381(PABPN1L) 102382268
AMJ: 102560911(PABPN1L) 106737025(PABPN1)
PSS: 102444712 102445724(PABPN1L)
CPIC: 101932126(PABPN1) 101939001(PABPN1L)
ACS: 100551702(pabpn1) 100555960(pabpn1l)
PVT: 110076239(PABPN1L) 110087838
PMUR: 107283481(PABPN1L) 107294807(PABPN1)
TSR: 106556480
PMUA: 114581472(PABPN1) 114602928(PABPN1L)
XLA: 380411(pabpn1.L) 398201(pabpn1.S) 398516(pabpn1l.L) 403372(pabpn1l.S)
XTR: 407911(pabpn1) 549106(pabpn1l)
NPR: 108786771 108787722(PABPN1L)
DRE: 406543(pabpn1)
IPU: 108256547(PABPN1) 108259598(pabpn1l) 108265929
PHYP: 113541161(pabpn1) 113546748(pabpn1l)
AMEX: 103031724(pabpn1l) 103033460(pabpn1)
EEE: 113575711(pabpn1l) 113586084(pabpn1)
TRU: 101063888(pabpn1l) 101071360(pabpn1)
LCO: 104922767 104927509(pabpn1)
NCC: 104941946(pabpn1) 104947116(pabpn1l)
MZE: 101464473(pabpn1) 101471233(pabpn1l)
ONL: 100705289(pabpn1) 100708349(pabpn1l) 109198957
OLA: 101157012(pabpn1) 101170990(pabpn1l)
XMA: 102229160(pabpn1) 102231342(pabpn1l)
XCO: 114136549(pabpn1) 114142562(pabpn1l)
PRET: 103462375(pabpn1l) 103482315(pabpn1)
CVG: 107091372(pabpn1l) 107095250(pabpn1)
NFU: 107381171(pabpn1l) 107382693(pabpn1)
KMR: 108229120(pabpn1l) 108245444(pabpn1)
ALIM: 106529765(pabpn1) 106535461(pabpn1l)
AOCE: 111568096 111579350(pabpn1) 111588397(pabpn1l)
CSEM: 103376922(pabpn1) 103378657(pabpn1l)
POV: 109624715(pabpn1l) 109629749(pabpn1)
LCF: 108887658(pabpn1l) 108898238(pabpn1)
SDU: 111238407(pabpn1l) 111239286(pabpn1)
SLAL: 111648218(pabpn1) 111668278(pabpn1l)
HCQ: 109516996(pabpn1) 109519695(pabpn1l)
BPEC: 110166314(pabpn1) 110172903(pabpn1l)
MALB: 109965981(pabpn1) 109966233(pabpn1l)
ELS: 105017077(pabpn1l) 105019495(pabpn1)
LCM: 102352183(PABPN1L) 102354373(PABPN1)
CIN: 100181118
SPU: 594592
APLC: 110981317
SKO: 100368893
DME: Dmel_CG2163(Pabp2)
DER: 6542110
DSI: Dsimw501_GD10545(Dsim_GD10545)
DYA: Dyak_GE19180(Dyak_Pabp2)
DSR: 110180723
DPE: 6592762
DMN: 108158694
DWI: 6652094
DAZ: 108615741
DNV: 108654627
DHE: 111600794
MDE: 101888292
LCQ: 111686720
AAG: 5566366
AALB: 109405147
AME: 409558
BIM: 100746296
BTER: 100646108
CCAL: 108632391
OBB: 114880343
MPHA: 105839273
AEC: 105145034
ACEP: 105619361
PBAR: 105430263
VEM: 105565113
HST: 105188796
DQU: 106750034
CFO: 105256043
LHU: 105668535
PGC: 109862683
OBO: 105287491
NVI: 103317853
CSOL: 105361871
MDL: 103580428
TCA: 664338
DPA: 109540448
BMOR: 733078(Pabn1)
BMAN: 114239399
PMAC: 106713596
PRAP: 110991389
HAW: 110370605
TNL: 113503873
PXY: 105391434
API: 100159220
DNX: 107170278
AGS: 114119777
RMD: 113550135
BTAB: 109029723
CLEC: 106664213
ZNE: 110838734
FCD: 110842469
PVM: 113800275
TUT: 107368749
DPTE: 113791335
PTEP: 107453921
CEL: CELE_C17E4.5(pabp-2) CELE_EEED8.12(EEED8.12) CELE_EEED8.4(EEED8.4) CELE_T08B6.5(sgnh-1)
CBR: CBG03741(Cbr-pabp-2) CBG05376 CBG05418
BMY: Bm1_48895
PCAN: 112576721
CRG: 105334534
MYI: 110453397
OBI: 106873873
SHX: MS3_00808
EGL: EGR_09203
EPA: 110241565
ADF: 107327699
AMIL: 114954262
PDAM: 113665845
SPIS: 111325732
HMG: 100202412
AQU: 100633250
LJA: Lj0g3v0103959.1(Lj0g3v0103959.1) Lj0g3v0103959.2(Lj0g3v0103959.2) Lj0g3v0103959.3(Lj0g3v0103959.3) Lj0g3v0103959.4(Lj0g3v0103959.4) Lj0g3v0103959.5(Lj0g3v0103959.5) Lj0g3v0225609.1(Lj0g3v0225609.1) Lj0g3v0251069.1(Lj0g3v0251069.1) Lj0g3v0251069.2(Lj0g3v0251069.2)
DOSA: Os02t0757900-01(Os02g0757900) Os06t0219600-01(Os06g0219600)
ATS: 109740292(LOC109740292) 109750230(LOC109750230) 109751893(LOC109751893)
APRO: F751_3091
SCE: YIR001C(SGN1)
ERC: Ecym_4483
KMX: KLMA_50386(SGN1)
NCS: NCAS_0A07700(NCAS0A07700)
NDI: NDAI_0H02090(NDAI0H02090)
TBL: TBLA_0A01040(TBLA0A01040)
TDL: TDEL_0H03080(TDEL0H03080)
KAF: KAFR_0K01170(KAFR0K01170)
CAL: CAALFM_C209650WA(CaO19.1389) CAALFM_C700250CA(CaO19.7097)
SLB: AWJ20_4776(SGN1)
NCR: NCU03946
NTE: NEUTE1DRAFT69316(NEUTE1DRAFT_69316)
MGR: MGG_07252
SSCK: SPSK_05497
MAW: MAC_07733
MAJ: MAA_00028
CMT: CCM_01093
BFU: BCIN_04g00440(Bcsgn1)
MBE: MBM_07952
ANI: AN1340.2
ANG: ANI_1_152074(An08g01040)
ABE: ARB_08025
TVE: TRV_04339
PTE: PTT_16602
SPO: SPBC16E9.12c(pab2)
CNE: CNB04570
CNB: CNBB1200
MGL: MGL_0778
MRT: MRET_0037
DDI: DDB_G0277371(pabpn1)
DFA: DFA_01901(pabpn1)
EHI: EHI_009470(47.t00012) EHI_092630(204.t00007)
PYO: PY17X_0828100(PY00009)
PCB: PCHAS_082510(PC000174.00.0)
TAN: TA03875
TPV: TP03_0088
BBO: BBOV_I002350(19.m02195)
CPV: cgd6_410
TPS: THAPSDRAFT_268661(pab1)
SPAR: SPRG_02264
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Fan X, Dion P, Laganiere J, Brais B, Rouleau GA
  Title
Oligomerization of polyalanine expanded PABPN1 facilitates nuclear protein aggregation that is associated with cell death.
  Journal
Hum Mol Genet 10:2341-51 (2001)
DOI:10.1093/hmg/10.21.2341
  Sequence
[hsa:8106]
Reference
  Authors
Benoit B, Nemeth A, Aulner N, Kuhn U, Simonelig M, Wahle E, Bourbon HM
  Title
The Drosophila poly(A)-binding protein II is ubiquitous throughout Drosophila development and has the same function in mRNA polyadenylation as its bovine homolog in vitro.
  Journal
Nucleic Acids Res 27:3771-8 (1999)
DOI:10.1093/nar/27.19.3771
  Sequence
Reference
PMID:9462747
  Authors
Brais B, Bouchard JP, Xie YG, Rochefort DL, Chretien N, Tome FM, Lafreniere RG, Rommens JM, Uyama E, Nohira O, Blumen S, Korczyn AD, Heutink P, Mathieu J, Duranceau A, Codere F, Fardeau M, Rouleau GA
  Title
Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy.
  Journal
Nat Genet 18:164-7 (1998)
DOI:10.1038/ng0298-164
  Sequence
[hsa:8106]

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