KEGG   ORTHOLOGY: K14802
Entry
K14802                      KO                                     

Name
DRS2, ATP8A
Definition
phospholipid-transporting ATPase [EC:7.6.2.1]
Disease
H01204  Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03009 Ribosome biogenesis
    K14802  DRS2, ATP8A; phospholipid-transporting ATPase
Enzymes [BR:ko01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.1  P-type phospholipid transporter
     K14802  DRS2, ATP8A; phospholipid-transporting ATPase
Ribosome biogenesis [BR:ko03009]
 Eukaryotic type
  Pre-40S particles
   Other pre-40S particles
    K14802  DRS2, ATP8A; phospholipid-transporting ATPase
Other DBs
GO: 0004012
TC: 3.A.3.8
Genes
HSA: 10396(ATP8A1) 51761(ATP8A2)
PTR: 461189(ATP8A1) 467238(ATP8A2)
PPS: 100986009(ATP8A2) 100989463(ATP8A1)
GGO: 101126969(ATP8A1) 101127464(ATP8A2)
PON: 100442324 100446676(ATP8A1)
NLE: 100582757(ATP8A2) 100592609(ATP8A1)
MCC: 702630(ATP8A1) 709311(ATP8A2)
MCF: 102145170(ATP8A1) 102145479(ATP8A2)
CSAB: 103246160(ATP8A1) 103249035(ATP8A2)
RRO: 104659980(ATP8A2) 104662686(ATP8A1)
CJC: 100386296(ATP8A2) 100404856(ATP8A1)
SBQ: 101043679(ATP8A2) 101047760(ATP8A1)
MMU: 11980(Atp8a1) 50769(Atp8a2)
MCAL: 110294210(Atp8a1) 110309426(Atp8a2)
MPAH: 110325320(Atp8a2) 110330999(Atp8a1)
RNO: 289615(Atp8a1) 691889(Atp8a2)
MUN: 110555694(Atp8a2) 110559503(Atp8a1)
CGE: 100756975(Atp8a1) 100763581(Atp8a2)
NGI: 103727177(Atp8a2) 103729228(Atp8a1)
HGL: 101721978(Atp8a2) 101725406(Atp8a1)
CCAN: 109685508 109690312(Atp8a1)
TUP: 102494521(ATP8A1) 102496769(ATP8A2) 102498413
CFA: 100687016(ATP8A2) 486036 607976(ATP8A1)
AML: 100465593(ATP8A1) 100477848(ATP8A2) 105239758
PTG: 102950974(ATP8A1) 102958974 102959813(ATP8A2)
PPAD: 109245621(ATP8A1) 109266144 109266145(ATP8A2)
BTA: 317692(ATP8A1) 508723(ATP8A2) 536660
BOM: 102273088(ATP8A1) 102277904 102280627(ATP8A2)
BBUB: 102398473(ATP8A1) 102411792(ATP8A2) 102412116
CHX: 102176951(ATP8A1) 102190971 102191532(ATP8A2)
BACU: 102998822(ATP8A2) 103005083(ATP8A1)
LVE: 103071186(ATP8A1) 103084501(ATP8A2)
OOR: 101269947(ATP8A1) 101282182(ATP8A2)
DLE: 111170198(ATP8A1) 111175171(ATP8A2)
PCAD: 102974200(ATP8A1) 102994737
ECB: 100059537 100062902(ATP8A1)
EPZ: 103559055(ATP8A2) 103562093(ATP8A1) 103563114
EAI: 106832433 106832434(ATP8A2) 106841270(ATP8A1)
MYB: 102242688(ATP8A1) 102251041(ATP10A) 102263207(ATP8A2)
MYD: 102752128(ATP8A2) 102770925(ATP8A1)
MNA: 107532439(ATP8A1) 107546456(ATP8A2)
HAI: 109374158(ATP8A1) 109387513(ATP8A2)
DRO: 112296209(ATP8A2) 112316913(ATP8A1)
PALE: 102882432(ATP8A1) 102894916(ATP8A2)
RAY: 107503442(ATP8A2) 107518748(ATP8A1)
MJV: 108389522(ATP8A1) 108398088
MDO: 100020627(ATP8A1) 100024643(ATP8A2)
SHR: 100917108(ATP8A1) 100927847(ATP8A2)
PCW: 110211509(ATP8A1) 110215560(ATP8A2)
OAA: 100089451(ATP8A1) 100090122(ATP8A2)
GGA: 418936(ATP8A2) 422776(ATP8A1)
MGP: 100546894(ATP8A2) 100547261(ATP8A1)
CJO: 107308305(ATP8A2) 107313794(ATP8A1)
NMEL: 110389142(ATP8A2) 110397611(ATP8A1)
APLA: 101799384(ATP8A2) 101802029(ATP8A1)
ACYG: 106048052(ATP8A1) 106049613
TGU: 100220565(ATP8A2) 100228586(ATP8A1)
LSR: 110470761(ATP8A2) 110482587(ATP8A1)
SCAN: 103824959(ATP8A1) 103827323(ATP8A2)
GFR: 102038476(ATP8A1) 102040876(ATP8A2)
FAB: 101811109(ATP8A2) 101812034(ATP8A1)
PHI: 102103842(ATP8A1) 102105284(ATP8A2)
PMAJ: 107203029(ATP8A1) 107210219(ATP8A2)
CCAE: 111923460(ATP8A2) 111928456(ATP8A1)
CCW: 104689880(ATP8A2) 104690658(ATP8A1)
ETL: 114057580(ATP8A2) 114061164(ATP8A1)
FPG: 101910802 101913068(ATP8A2) 101924039(ATP8A1)
FCH: 102049838(ATP8A1) 102056518(ATP8A2)
CLV: 102096479(ATP8A2) 102098463(ATP8A1)
EGZ: 104128461(ATP8A1) 104131691(ATP8A2)
NNI: 104020754(ATP8A1) 104023029(ATP8A2)
ACUN: 113479210(ATP8A1) 113482614(ATP8A2)
PADL: 103920102(ATP8A2) 103923997(ATP8A1)
AAM: 106490188(ATP8A1) 106500401(ATP8A2)
ASN: 102376473(ATP8A1) 102386600
AMJ: 102565160(ATP8A2) 102571061(ATP8A1)
PSS: 102443448(ATP8A1) 102452052(ATP8A2)
CMY: 102931155(ATP8A2) 102946813(ATP8A1)
CPIC: 101930978(ATP8A2) 101945397(ATP8A1)
ACS: 100554182(atp8a2) 100564127(atp8a1)
PVT: 110075221(ATP8A1) 110076458(ATP8A2)
PBI: 103058631 103066857(ATP8A1)
PMUR: 107288419(ATP8A2) 107297900(ATP8A1)
TSR: 106543485(ATP8A1) 106554038(ATP8A2)
PMUA: 114595743(ATP8A2) 114604758(ATP8A1)
GJA: 107112573(ATP8A1) 107112633(ATP8A2)
XLA: 108698176(atp8a1.L) 108706578(atp8a1.S) 108707568
XTR: 101730757(atp8a2) 733571(atp8a1)
NPR: 108793825(ATP8A1) 108795175(ATP8A2)
DRE: 100330943(atp8a2)
IPU: 108256710(atp8a2) 108269037(atp8a1)
PHYP: 113529104(atp8a1) 113541098(atp8a2)
AMEX: 103024439(atp8a2) 103026348(atp8a1)
EEE: 113576124(atp8a2) 113585295(atp8a1)
TRU: 101069525(atp8a2) 101075533(atp8a1)
LCO: 104924965(atp8a2) 104927925(atp8a1)
NCC: 104956972(atp8a1)
MZE: 101472900(atp8a1) 101485339(atp8a2)
ONL: 100698566(atp8a2) 100707986(atp8a1)
OLA: 101162251(atp8a2) 101175086(atp8a1)
XMA: 102221031(atp8a2) 102231583(atp8a1)
XCO: 114136709(atp8a2) 114138866(atp8a1)
PRET: 103456637(atp8a2) 103471508(atp8a1)
NFU: 107379161(atp8a1) 107382858(atp8a2)
KMR: 108230387(atp8a2) 108231306(atp8a1)
ALIM: 106513419(atp8a2) 106525363(atp8a1) 106536282
AOCE: 111570681(atp8a2) 111582990 111583277(atp8a1) 111583617
CSEM: 103377244(atp8a2) 103390601(atp8a1)
LCF: 108881748(atp8a2) 108895351(atp8a1)
SDU: 111220916(atp8a2) 111232617(atp8a1)
SLAL: 111648157(atp8a1) 111662997(atp8a2)
HCQ: 109514038(atp8a2) 109515841(atp8a1)
BPEC: 110158830(atp8a1) 110160973
MALB: 109960100(atp8a2) 109972040(atp8a1)
ELS: 105015964 105021962(atp8a2) 105028279(atp8a1)
LCM: 102354915(ATP8A2)
CMK: 103175876(atp8a1) 103183262(atp8a2)
BFO: 118418791
CIN: 100186827
SPU: 764069
APLC: 110976158
SKO: 100369974
DME: Dmel_CG42321(ATP8A)
DER: 6549482
DSE: 6608993
DSI: Dsimw501_GD25762(Dsim_GD25762)
DAN: 6494051
DSR: 110180496
DPE: 6590695
DWI: 6637958
DAZ: 108615321
DNV: 108654314
DHE: 111598025
DVI: 6625169
MDE: 101899577
LCQ: 111686131
AAG: 5566589
AME: 552074
BIM: 100748672
BTER: 100651947
CCAL: 108625227
OBB: 114876395
SOC: 105195215
MPHA: 105828597
AEC: 105146443
ACEP: 105626520
PBAR: 105422832
VEM: 105568780
HST: 105188273
DQU: 106745602
CFO: 105248267
LHU: 105669563
PGC: 109859162
OBO: 105282219
PCF: 106792270
CSOL: 105362344
MDL: 103572280
TCA: 663307
DPA: 109535391
ATD: 109598113
NVL: 108568056
BMOR: 101746988
BMAN: 114243370
PMAC: 106709599
PRAP: 110998343
HAW: 110375191
TNL: 113507302
BTAB: 109030084
CLEC: 106669096
ZNE: 110828371
PVM: 113806423
TUT: 107367187
DPTE: 113795583
CSCU: 111617359
PTEP: 107446997
CEL: CELE_Y49E10.11(tat-1)
CBR: CBG11754(Cbr-tat-1)
BMY: Bm1_41570
TSP: Tsp_05177
PCAN: 112559893
CRG: 105348731
MYI: 110449526
OBI: 106872891
SHX: MS3_10423
EGL: EGR_04311
NVE: 5507451
EPA: 110252568
ADF: 107348700
AMIL: 114950759
PDAM: 113686470
SPIS: 111344616
DGT: 114524547
HMG: 100209479
ATH: AT1G59820(ALA3) AT5G04930(ALA1)
LJA: Lj0g3v0004229.1(Lj0g3v0004229.1) Lj0g3v0104529.1(Lj0g3v0104529.1) Lj0g3v0253989.1(Lj0g3v0253989.1) Lj0g3v0253989.2(Lj0g3v0253989.2) Lj1g3v2471250.1(Lj1g3v2471250.1) Lj1g3v2471250.2(Lj1g3v2471250.2) Lj2g3v1353620.2(Lj2g3v1353620.2)
DOSA: Os01t0277600-00(Os01g0277600) Os03t0326200-01(Os03g0326200) Os03t0334700-01(Os03g0334700) Os10t0412000-01(Os10g0412000)
MNG: MNEG_2645
APRO: F751_0465
SCE: YAL026C(DRS2)
ERC: Ecym_5071
KMX: KLMA_50118(DRS2)
NCS: NCAS_0F01710(NCAS0F01710)
NDI: NDAI_0H02560(NDAI0H02560)
TPF: TPHA_0H02720(TPHA0H02720)
TBL: TBLA_0A04620(TBLA0A04620)
TDL: TDEL_0H03790(TDEL0H03790)
KAF: KAFR_0K00630(KAFR0K00630)
PIC: PICST_33561(DRS2)
CAL: CAALFM_C307230WA(CaO19.6778)
SLB: AWJ20_4638(DRS2) AWJ20_4639(DRS2)
BNN: FOA43_004221(DRS2)
NCR: NCU00352
NTE: NEUTE1DRAFT82209(NEUTE1DRAFT_82209)
MGR: MGG_12922
SSCK: SPSK_03875
MAW: MAC_03722
MAJ: MAA_05889
CMT: CCM_01425
BFU: BCIN_16g03280(Bcdrs2)
MBE: MBM_00404
ANI: AN6112.2
ANG: ANI_1_558104(An12g04500)
PBL: PAAG_12472(PAAG_07970)
ABE: ARB_04946
TVE: TRV_07132
PTE: PTT_08728
CNE: CNA03720
CNB: CNBA3510
TASA: A1Q1_05866
ABP: AGABI1DRAFT119321(AGABI1DRAFT_119321)
ABV: AGABI2DRAFT185198(AGABI2DRAFT_185198)
MGL: MGL_3263
MRT: MRET_2430
EHI: EHI_141350(309.t00009) EHI_188210(75.t00023)
PCB: PCHAS_143680(PC000483.03.0)
BBO: BBOV_I000770(16.m00775) BBOV_IV001830(21.m02975)
SMIN: v1.2.008818.t1(symbB.v1.2.008818.t1) v1.2.009532.t1(symbB.v1.2.009532.t1) v1.2.009535.t1(symbB.v1.2.009535.t1) v1.2.011936.t1(symbB.v1.2.011936.t1) v1.2.014487.t1(symbB.v1.2.014487.t1) v1.2.017624.t1(symbB.v1.2.017624.t1) v1.2.017624.t2(symbB.v1.2.017624.t2) v1.2.025610.t1(symbB.v1.2.025610.t1)
PTI: PHATRDRAFT_52368(ATPase-P4)
 » show all
Reference
PMID:8247005
  Authors
Ripmaster TL, Vaughn GP, Woolford JL Jr
  Title
DRS1 to DRS7, novel genes required for ribosome assembly and function in Saccharomyces cerevisiae.
  Journal
Mol Cell Biol 13:7901-12 (1993)
DOI:10.1128/MCB.13.12.7901
  Sequence
[sce:YAL026C]
Reference
  Authors
Paterson JK, Renkema K, Burden L, Halleck MS, Schlegel RA, Williamson P, Daleke DL
  Title
Lipid specific activation of the murine P4-ATPase Atp8a1 (ATPase II).
  Journal
Biochemistry 45:5367-76 (2006)
DOI:10.1021/bi052359b
  Sequence
[mmu:11980]

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