KEGG   ORTHOLOGY: K15040
Entry
K15040                      KO                                     
Symbol
VDAC2
Name
voltage-dependent anion channel protein 2
Pathway
map04020  Calcium signaling pathway
map04022  cGMP-PKG signaling pathway
map04216  Ferroptosis
map04217  Necroptosis
map04218  Cellular senescence
map04613  Neutrophil extracellular trap formation
map04621  NOD-like receptor signaling pathway
map04979  Cholesterol metabolism
map05010  Alzheimer disease
map05012  Parkinson disease
map05016  Huntington disease
map05017  Spinocerebellar ataxia
map05020  Prion disease
map05022  Pathways of neurodegeneration - multiple diseases
map05166  Human T-cell leukemia virus 1 infection
map05208  Chemical carcinogenesis - reactive oxygen species
map05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K15040  VDAC2; voltage-dependent anion channel protein 2
   04022 cGMP-PKG signaling pathway
    K15040  VDAC2; voltage-dependent anion channel protein 2
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    K15040  VDAC2; voltage-dependent anion channel protein 2
   04217 Necroptosis
    K15040  VDAC2; voltage-dependent anion channel protein 2
   04218 Cellular senescence
    K15040  VDAC2; voltage-dependent anion channel protein 2
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    K15040  VDAC2; voltage-dependent anion channel protein 2
   04621 NOD-like receptor signaling pathway
    K15040  VDAC2; voltage-dependent anion channel protein 2
  09154 Digestive system
   04979 Cholesterol metabolism
    K15040  VDAC2; voltage-dependent anion channel protein 2
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K15040  VDAC2; voltage-dependent anion channel protein 2
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K15040  VDAC2; voltage-dependent anion channel protein 2
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K15040  VDAC2; voltage-dependent anion channel protein 2
   05012 Parkinson disease
    K15040  VDAC2; voltage-dependent anion channel protein 2
   05016 Huntington disease
    K15040  VDAC2; voltage-dependent anion channel protein 2
   05017 Spinocerebellar ataxia
    K15040  VDAC2; voltage-dependent anion channel protein 2
   05020 Prion disease
    K15040  VDAC2; voltage-dependent anion channel protein 2
   05022 Pathways of neurodegeneration - multiple diseases
    K15040  VDAC2; voltage-dependent anion channel protein 2
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K15040  VDAC2; voltage-dependent anion channel protein 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K15040  VDAC2; voltage-dependent anion channel protein 2
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K15040  VDAC2; voltage-dependent anion channel protein 2
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial protein import machinery
  Outer membrane
   Porin
    K15040  VDAC2; voltage-dependent anion channel protein 2
Ion channels [BR:ko04040]
 Chloride channels
  Maxi chloride channel (VDAC)
   K15040  VDAC2; voltage-dependent anion channel protein 2
Other DBs
GO: 0008308
TC: 1.B.8.1
Genes
HSA: 7417(VDAC2)
PTR: 738876(VDAC2)
PPS: 100990596(VDAC2)
GGO: 101148105(VDAC2)
PON: 100456290(VDAC2)
NLE: 100588414(VDAC2)
MCC: 704257(VDAC2)
MCF: 101865627(VDAC2)
MTHB: 126962446
CSAB: 103215964(VDAC2)
CATY: 105597362(VDAC2)
PANU: 101009552(VDAC2)
TGE: 112631163(VDAC2)
RRO: 104671883(VDAC2)
RBB: 108529513(VDAC2)
TFN: 117082746(VDAC2)
PTEH: 111537825(VDAC2)
CJC: 100399481(VDAC2)
SBQ: 101038914(VDAC2)
CSYR: 103263904(VDAC2)
MMUR: 105866328(VDAC2)
LCAT: 123650270(VDAC2)
OGA: 100962937(VDAC2)
MMU: 22334(Vdac2)
MCAL: 110309560(Vdac2)
MPAH: 110325370(Vdac2)
RNO: 83531(Vdac2)
MCOC: 116084380(Vdac2)
MUN: 110548867(Vdac2)
CGE: 100761812(Vdac2)
MAUA: 101826831(Vdac2)
PLEU: 114700220(Vdac2)
MORG: 121435027(Vdac2) 121438629
AAMP: 119800149(Vdac2)
NGI: 103747445(Vdac2) 103747985
HGL: 101723570(Vdac2)
CPOC: 100723838(Vdac2)
CCAN: 109693642(Vdac2) 109700211
DORD: 105992684(Vdac2)
DSP: 122116516(Vdac2)
NCAR: 124984706
OCU: 100009473(VDAC2)
OPI: 101518154 101532282(VDAC2)
TUP: 102476815(VDAC2)
GVR: 103605434(VDAC2)
CFA: 479255(VDAC2)
CLUD: 112651940(VDAC2)
VVP: 112927770(VDAC2)
VLG: 121486531(VDAC2)
AML: 100465507(VDAC2)
UMR: 103667846(VDAC2)
UAH: 113259206(VDAC2)
UAR: 123782868(VDAC2) 123788811
ELK: 111145442
LLV: 125084591
MPUF: 101674296(VDAC2)
ORO: 101374903(VDAC2)
EJU: 114214136(VDAC2)
ZCA: 113923387(VDAC2)
MLX: 118021936(VDAC2)
NSU: 110577984 110589660(VDAC2)
LWW: 102747348(VDAC2)
FCA: 101092793(VDAC2)
PYU: 121036822(VDAC2)
PBG: 122493482(VDAC2)
LRUF: 124506927
PTG: 102951163(VDAC2)
PPAD: 109264442(VDAC2)
AJU: 106969683(VDAC2)
HHV: 120233718(VDAC2) 120234907
BTA: 282120(VDAC2)
BOM: 102281314(VDAC2)
BIU: 109553821(VDAC2)
BBUB: 102391970(VDAC2)
BBIS: 104997530(VDAC2)
CHX: 102169457(VDAC2)
OAS: 101103533(VDAC2)
ODA: 120865264(VDAC2)
CCAD: 122446361(VDAC2)
SSC: 397659(VDAC2)
CFR: 102520541(VDAC2) 106730896
CBAI: 105075349(VDAC2)
CDK: 105092440(VDAC2)
VPC: 102540832(VDAC2)
BACU: 103000396(VDAC2)
LVE: 103087514(VDAC2)
OOR: 101276520(VDAC2)
DLE: 111183542(VDAC2)
PCAD: 102995871(VDAC2)
ECB: 100064276(VDAC2)
EPZ: 103560633(VDAC2)
EAI: 106843557(VDAC2)
MYB: 102245606(VDAC2)
MYD: 102751339(VDAC2)
MMYO: 118670177(VDAC2)
MLF: 102431583(VDAC2)
MNA: 107545842(VDAC2)
PKL: 118719112(VDAC2)
HAI: 109372707(VDAC2) 109392355
DRO: 112303041 112305359(VDAC2)
SHON: 118993509(VDAC2)
AJM: 119038134(VDAC2) 119053810
PDIC: 114491433 114496446(VDAC2)
PHAS: 123820947(VDAC2)
MMF: 118632500(VDAC2)
RFQ: 117036062(VDAC2)
PALE: 102898192(VDAC2)
PGIG: 120609565(VDAC2)
PVP: 105288878(VDAC2)
RAY: 107518519(VDAC2)
MJV: 108393309(VDAC2)
TOD: 119234900(VDAC2) 119260988
SARA: 101553627(VDAC2)
LAV: 100667776(VDAC2)
TMU: 101346677
ETF: 101649902(VDAC2)
DNM: 101420466 101447422(VDAC2)
MDO: 100012461(VDAC2)
GAS: 123232936(VDAC2)
SHR: 100920408(VDAC2)
PCW: 110221481(VDAC2)
OAA: 100075011(VDAC2)
GGA: 395498(VDAC2)
PCOC: 116235073(VDAC2)
MGP: 100540440(VDAC2)
CJO: 107315829(VDAC2)
NMEL: 110399852(VDAC2)
ACYG: 106032935(VDAC2)
AFUL: 116491183(VDAC2)
TGU: 100221276(VDAC2) 116807251
LSR: 110471741(VDAC2)
SCAN: 103814011(VDAC2)
PMOA: 120510925(VDAC2)
OTC: 121336041(VDAC2)
PRUF: 121356693(VDAC2)
GFR: 102038775(VDAC2)
FAB: 101810113(VDAC2)
PHI: 102102486(VDAC2)
PMAJ: 107206958(VDAC2)
CCAE: 111931054(VDAC2)
CCW: 104697612(VDAC2)
CBRC: 103623697(VDAC2)
ETL: 114055910(VDAC2)
ZAB: 102060788(VDAC2)
ACHL: 103803983(VDAC2)
FPG: 101915240(VDAC2)
FCH: 102057472(VDAC2)
CLV: 102088857(VDAC2)
EGZ: 104129097(VDAC2)
NNI: 104015955(VDAC2)
PLET: 104615693(VDAC2)
PCRI: 104025300
PCAO: 104040230(VDAC2)
ACUN: 113481457(VDAC2)
TALA: 104360275(VDAC2)
PADL: 103915597(VDAC2)
AFOR: 103897578(VDAC2)
ACHC: 115348118(VDAC2)
HALD: 104315983(VDAC2)
HLE: 104831917(VDAC2)
AGEN: 126043153
GCL: 127017618
CCRI: 104168142(VDAC2)
CSTI: 104551083(VDAC2)
EHS: 104517397(VDAC2)
CMAC: 104474950(VDAC2)
MUI: 104535115(VDAC2)
FGA: 104072659(VDAC2)
GSTE: 104262729(VDAC2)
LDI: 104341654(VDAC2)
MNB: 103777795(VDAC2)
OHA: 104335769(VDAC2)
NNT: 104411577(VDAC2)
DPUB: 104297659(VDAC2)
PGUU: 104459891(VDAC2)
ACAR: 104519173(VDAC2)
CPEA: 104391451(VDAC2)
AVIT: 104273602(VDAC2)
CVF: 104289665(VDAC2)
CUCA: 104067934(VDAC2)
TEO: 104378408(VDAC2)
BRHI: 104493738(VDAC2)
AAM: 106498931(VDAC2)
AROW: 112961045(VDAC2)
NPD: 112951455(VDAC2)
TGT: 104569123(VDAC2)
DNE: 112993295(VDAC2)
SCAM: 104141752(VDAC2)
ASN: 102381104(VDAC2)
AMJ: 102559245(VDAC2)
CPOO: 109324118(VDAC2)
GGN: 109287366(VDAC2)
PSS: 102450498(VDAC2)
CMY: 102946880(VDAC2)
CPIC: 101951352(VDAC2)
TST: 117879866(VDAC2)
CABI: 116834229(VDAC2)
MRV: 120368580(VDAC2)
ACS: 100565441(vdac2)
PVT: 110080326(VDAC2)
SUND: 121926063(VDAC2)
PBI: 103049275(VDAC2)
PMUR: 107298679(VDAC2)
CTIG: 120306414(VDAC2)
TSR: 106537461(VDAC2)
PGUT: 117676153(VDAC2)
VKO: 123018315(VDAC2)
PMUA: 114597053(VDAC2)
ZVI: 118096309(VDAC2)
GJA: 107109962(VDAC2)
STOW: 125436338(VDAC2)
XLA: 734449(vdac2.S)
XTR: 548947(vdac2)
NPR: 108788404(VDAC2)
RTEM: 120909038(VDAC2)
BBUF: 121003508(VDAC2)
BGAR: 122940983(VDAC2)
DRE: 322126(vdac2)
PPRM: 120462038 120479649(vdac2)
MAMB: 125255500 125276634(vdac2)
IPU: 108263545(vdac2) 108273854
PHYP: 113543440(vdac2)
SMEO: 124388503 124403773(vdac2)
TFD: 113634812 113639914(vdac2)
ELY: 117247157 117248722(vdac2)
EFO: 125880939 125903120(vdac2)
PLEP: 121954691(vdac2) 121958529
SLUC: 116054975(vdac2) 116061214
ECRA: 117936885 117960893(vdac2)
GAT: 120819421 120820659(vdac2)
PPUG: 119212861 119213928(vdac2)
MSAM: 119916049 119917586(vdac2)
CUD: 121511276(vdac2) 121528627
ALAT: 119009719 119033916(vdac2)
ONL: 100700892 100703459(vdac2)
OAU: 116309854(vdac2) 116327494
OML: 112154172 112161679(vdac2)
GAF: 122822701 122842994(vdac2)
CTUL: 119774935 119792456(vdac2)
GMU: 124859648(vdac2) 124875481
KMR: 108245669(vdac2) 108249683
ALIM: 106515335(vdac2) 106517011
NWH: 119413071(vdac2) 119424019
AOCE: 111574785 111575545(vdac2)
HHIP: 117753359 117776021(vdac2)
HSP: 118100678 118119002(vdac2)
XGL: 120794839 120796336(vdac2)
HCQ: 109512544(vdac2) 109513410
BPEC: 110164408 110173602(vdac2)
BSPL: 114845680 114870699(vdac2)
SASA: 100846953(vdac2) 106577200(VDAC2) 106608573(VDAC2) 106611737(VDAC2)
AANG: 118219694(vdac2)
LOC: 102694933(vdac2)
PSEX: 120515492 120541564(vdac2)
LCM: 102366723(VDAC2)
CMK: 103182012(vdac2)
RTP: 109935019(vdac2)
BFO: 118411604
BBEL: 109466786
CIN: 100184654
SCLV: 120347347
SPU: 576005
APLC: 110977525
AJC: 117122875
SKO: 100376223
DME: Dmel_CG17137(Porin2) Dmel_CG6647(porin)
DSE: 6612072
DSI: Dsimw501_GD22218(Dsim_GD22218) Dsimw501_GD22219(Dsim_GD22219)
DYA: Dyak_GE13240(Dyak_porin) Dyak_GE13251
DAN: 6496888
DVI: 6628769
CCAT: 101459468
BOD: 106624123
MDE: 101900152
SCAC: 106083068
LCQ: 111681702
LSQ: 119604745
HIS: 119655606
ACOZ: 120957137
AARA: 120900368
ASTE: 118513400
CPII: 120424097
CNS: 116344948
AME: 551325
ALAB: 122721054
BIM: 100741933
BBIF: 117210273
BVK: 117241771
BVAN: 117157058
BTER: 100651968
BPYO: 122573913
CCAL: 108625020
MGEN: 117227466
NMEA: 116430930
CGIG: 122396010
MPHA: 105837482
AEC: 105152380
ACEP: 105626437
PBAR: 105429395
HST: 105187903
DQU: 106748225
CFO: 105255405
OBO: 105276935
PFUC: 122516376
VPS: 122628383
TPRE: 106650662
MDL: 103571037
CGLO: 123273457
FAS: 105266127
DAM: 107048312
AGIF: 122853270
CINS: 118074179
LHT: 122507847
TCA: 662925
DPA: 109544496
SOY: 115891655
ATD: 109609187
CSET: 123316279
AGB: 108915984
NVL: 108561285
APLN: 108732629
PPYR: 116178649
BMOR: 101739703
BMAN: 114242363
MSEX: 115444370
BANY: 112052285
NIQ: 126771570
PMAC: 106721007
PPOT: 106110929
PXU: 106126798
PRAP: 111001634
PBX: 123714028
PNAP: 125060247
ZCE: 119839882
CCRC: 123698124
HAW: 110375794
HZE: 124638702
TNL: 113507651
SLIU: 111353849
OFU: 114353740
PXY: 105390784
CFEL: 113376913
API: 100158822
DNX: 107164306
CLEC: 106660834
HHAL: 106682202
FOC: 113202320
TPAL: 117646790
ZNE: 110831069
SGRE: 126329181
DMK: 116916753
DPZ: 124328364
PJA: 122247562
PCHN: 125039434
HAME: 121871374
PCLA: 123753241
PTRU: 123518075
HAZT: 108673543
LSM: 121113534
DSV: 119431989
RSAN: 119371713
RMP: 119163720
VDE: 111245874
VJA: 111271855
DPTE: 113790759
DFR: 124496704
CSCU: 111621297
CEL: CELE_R05G6.7(vdac-1)
CBR: CBG_05894
BMY: BM_BM5232(Bma-vdac-1)
TSP: Tsp_12419
PCAN: 112554731
BGT: 106057557
GAE: 121380260
HRF: 124134305
HRJ: 124261422
CRG: 105339176
MYI: 110449398
PMAX: 117327220
OBI: 106877054
OSN: 115223839
LAK: 106167163
NVE: 5502779
EPA: 110232000
ATEN: 116298539
ADF: 107357455
AMIL: 114976572
PDAM: 113684501
SPIS: 111340195
DGT: 114530995
XEN: 124438969
HMG: 100207044
AQU: 100637825
ATH: AT3G01280(VDAC1) AT5G15090(VDAC3) AT5G57490(VDAC4) AT5G67500(VDAC2)
LJA: Lj0g3v0086299.1(Lj0g3v0086299.1) Lj0g3v0086309.1(Lj0g3v0086309.1) Lj1g3v2942100.1(Lj1g3v2942100.1) Lj2g3v1034580.1(Lj2g3v1034580.1) Lj2g3v1968250.1(Lj2g3v1968250.1) Lj2g3v1968260.1(Lj2g3v1968260.1) Lj4g3v2093710.1(Lj4g3v2093710.1) Lj4g3v2093710.2(Lj4g3v2093710.2) Lj4g3v2093720.1(Lj4g3v2093720.1) Lj5g3v0308840.2(Lj5g3v0308840.2)
DOSA: Os01t0588200-01(Os01g0588200) Os01t0715500-00(Os01g0715500) Os03t0137500-01(Os03g0137500) Os03t0202200-01(Os03g0202200) Os05t0536200-01(Os05g0536200) Os09t0361400-01(Os09g0361400)
APRO: F751_3441
SCE: YIL114C(POR2) YNL055C(POR1)
ERC: Ecym_3292
KMX: KLMA_80163(POR1)
NCS: NCAS_0B06420(NCAS0B06420)
NDI: NDAI_0B03710(NDAI0B03710)
TPF: TPHA_0C03190(TPHA0C03190)
TBL: TBLA_0B05800(TBLA0B05800)
TDL: TDEL_0C04070(TDEL0C04070)
KAF: KAFR_0J01130(KAFR0J01130) KAFR_0J01550(KAFR0J01550)
KNG: KNAG_0E01870(KNAG0E01870) KNAG_0I01830(KNAG0I01830)
PIC: PICST_90315(POR1)
CAL: CAALFM_C104100CA(POR1)
SLB: AWJ20_1491(POR1)
NCR: NCU04304(por)
NTE: NEUTE1DRAFT115659(NEUTE1DRAFT_115659)
MGR: MGG_00968
SSCK: SPSK_08800
MAW: MAC_01165
MAJ: MAA_05569
CMT: CCM_00510
MBE: MBM_08014
ANI: AN4402.2
PBL: PAAG_12425(PAAG_07564)
ABE: ARB_02689
TVE: TRV_05433
PTE: PTT_01274
CNE: CNC05830
CNB: CNBC1350
TASA: A1Q1_06044
ABP: AGABI1DRAFT85125(AGABI1DRAFT_85125)
ABV: AGABI2DRAFT137226(AGABI2DRAFT_137226)
SCM: SCHCO_02644822(SCHCODRAFT_02644822)
MGL: MGL_2751
MRT: MRET_1759
DDI: DDB_G0271848(porA)
 » show all
Reference
PMID:8420959
  Authors
Blachly-Dyson E, Zambronicz EB, Yu WH, Adams V, McCabe ER, Adelman J, Colombini M, Forte M
  Title
Cloning and functional expression in yeast of two human isoforms of the outer mitochondrial membrane channel, the voltage-dependent anion channel.
  Journal
J Biol Chem 268:1835-41 (1993)
  Sequence
[hsa:7417]

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