KEGG   ORTHOLOGY: K15603
Entry
K15603                      KO                                     

Name
TCF4_12
Definition
transcription factor 4/12
Disease
H00756  Pitt-Hopkins syndrome
H00960  Fuchs corneal dystrophy
H02160  Craniosynostoses
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K15603  TCF4_12; transcription factor 4/12
Transcription factors [BR:ko03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   Ubiquitous (class A) factors
    K15603  TCF4_12; transcription factor 4/12
Genes
HSA: 6925(TCF4) 6938(TCF12)
PTR: 453466(TCF12) 455432(TCF4)
PPS: 100967508(TCF4) 100971979(TCF12)
GGO: 101133252(TCF12) 101134466(TCF4)
PON: 100445658(TCF4) 100460448(TCF12)
NLE: 100584380(TCF4) 100603993(TCF12)
MCC: 695814(TCF4) 699626(TCF12)
MCF: 101926020(TCF12) 102146624(TCF4)
CSAB: 103244236(TCF4) 103245569(TCF12)
RRO: 104670907(TCF12) 104672093(TCF4)
RBB: 108514101(TCF4) 108545082(TCF12)
CJC: 100396827(TCF4)
SBQ: 101038651(TCF12) 101053606(TCF4)
MMU: 21406(Tcf12) 21413(Tcf4)
MCAL: 110284855(Tcf4) 110301509(Tcf12)
MPAH: 110327284(Tcf12) 110332885(Tcf4)
RNO: 25720(Tcf12) 84382(Tcf4)
MUN: 110553517(Tcf12) 110565698(Tcf4)
CGE: 100767684(Tcf4) 100770871(Tcf12)
NGI: 103736199(Tcf4) 103745573(Tcf12)
HGL: 101703066(Tcf12) 101707519(Tcf4) 101716342
CCAN: 109688457(Tcf4) 109700401(Tcf12)
OCU: 100339415(TCF12) 100343311(TCF4)
TUP: 102475151(TCF12) 102502742(TCF4)
CFA: 100684199(TCF12) 403949(TCF4)
VVP: 112919281(TCF4) 112919700(TCF12)
AML: 100463792(TCF4) 100469676(TCF12)
UMR: 103664490(TCF4) 103676784(TCF12)
UAH: 113253440(TCF4) 113269667(TCF12)
ORO: 101377326(TCF12) 101383785(TCF4)
FCA: 101083852(TCF12) 101097354(TCF4)
PTG: 102953973(TCF4) 102971309(TCF12)
PPAD: 109262933(TCF12) 109275687(TCF4)
AJU: 106973782(TCF12) 106980944(TCF4)
BTA: 509039(TCF12) 534935(TCF4)
BOM: 102272322(TCF12) 102279847(TCF4)
BIU: 109565096(TCF12) 109577775(TCF4)
BBUB: 102397933(TCF4) 102404685(TCF12)
CHX: 102182876(TCF12) 102188726(TCF4)
OAS: 101119478(TCF12) 101120538(TCF4)
SSC: 100511671(TCF4) 100621557(TCF12)
CFR: 102510066(TCF4) 102513896(TCF12)
CDK: 105088665(TCF12) 105103593(TCF4)
BACU: 102999136(TCF4) 103013430(TCF12)
LVE: 103074792(TCF12) 103087568(TCF4)
OOR: 101272769(TCF12) 101287607(TCF4)
DLE: 111177652(TCF12) 111180239(TCF4)
PCAD: 102984739(TCF4) 102987931(TCF12)
ECB: 100049930(TCF4) 100068843(TCF12)
EPZ: 103564770 103566739(TCF4)
EAI: 106830052(TCF12) 106834912(TCF4)
MYB: 102244742(TCF4) 102246641(TCF12)
MYD: 102756485(TCF12) 102760928(TCF4)
MNA: 107533745(TCF12) 107546650(TCF4)
HAI: 109381743(TCF4) 109394959(TCF12)
DRO: 112311675(TCF12) 112322967(TCF4)
PALE: 102890499(TCF4) 102897474(TCF12)
RAY: 107502175(TCF4) 107518604(TCF12)
MJV: 108395142(TCF4) 108407634(TCF12)
LAV: 100657701(TCF4) 100663924(TCF12)
MDO: 100016603(TCF4) 100020031(TCF12)
SHR: 100926974(TCF4) 100934213(TCF12)
PCW: 110205221(TCF12) 110213940(TCF4)
OAA: 100079058(TCF4) 100083476(TCF12)
GGA: 396334(TCF12)
MGP: 100545950(TCF12)
CJO: 107307000 107318518(TCF12)
NMEL: 110390384(TCF4) 110391943 110403537(TCF12)
APLA: 101794113(TCF4) 101800291(TCF12)
ACYG: 106033695(TCF12) 106044895(TCF4)
TGU: 100226398(TCF12)
LSR: 110479221(TCF12) 110484130
SCAN: 103815986(TCF12)
GFR: 102043059(TCF12)
FAB: 101812179(TCF12)
PHI: 102105160(TCF4) 102111631(TCF12)
PMAJ: 107209206(TCF12)
CCAE: 111934160(TCF12) 111940942(TCF4)
CCW: 104683834(TCF12)
ETL: 114056356(TCF12) 114070283(TCF4)
FPG: 101918548(TCF12) 101918710(TCF4)
FCH: 102051805(TCF12) 102056886(TCF4)
CLV: 102087657(TCF12) 102098165(TCF4)
EGZ: 104125018(TCF4) 104130887(TCF12)
NNI: 104010834(TCF4) 104017162(TCF12)
ACUN: 113483797(TCF12) 113489845(TCF4)
PADL: 103914864(TCF12) 103916163(TCF4)
AAM: 106487079(TCF4) 106496451(TCF12)
ASN: 102381277(TCF12) 102381961(TCF4)
AMJ: 102559163(TCF12) 102567660(TCF4)
PSS: 102443474(TCF4) 102448137(TCF12)
CMY: 102936634(TCF4) 102942658(TCF12)
CPIC: 101939371(TCF4) 101944514(TCF12)
ACS: 100553875(tcf12) 100557374(tcf4)
PVT: 110074523(TCF12) 110082630(TCF4)
PBI: 103059180(TCF4) 103061151(TCF12)
PMUR: 107283155(TCF12) 107295560(TCF4)
TSR: 106542889(TCF12) 106554487(TCF4)
PMUA: 114584216(TCF12) 114606191(TCF4)
GJA: 107108697(TCF12) 107110996(TCF4)
XLA: 108718448(XE2.1) 373726(tcf4.S) 398335 399451(tcf12.L)
XTR: 100124777(tcf4) 100188922(tcf12)
NPR: 108789827 108804486(TCF4)
DRE: 100526651(tcf4) 407985(tcf12)
IPU: 100304623(tcf12) 100329230(eb1) 108274485 108279184(tcf4)
PHYP: 113529993 113535549(tcf4) 113540867(tcf12)
EEE: 113567638(tcf4) 113571804 113575724(tcf12)
TRU: 101072332 101072514(tcf4) 101078621(tcf12)
LCO: 104917815(tcf4) 104924301(tcf12) 104931421
MZE: 101465421(tcf12) 101468544 101473449(tcf4)
ONL: 100694308(tcf4) 100695208 100709496(tcf12)
OLA: 101158544(tcf4) 101161725 101162824(tcf12)
XMA: 102218818 102220903(tcf4) 102225476(tcf12)
XCO: 114143032(tcf12) 114149016(tcf4) 114159419
PRET: 103460417(tcf4) 103462525(tcf12) 103466449
NFU: 107375077(tcf4) 107381382(tcf12) 107388629
KMR: 108228252(tcf12) 108229889 108245755(tcf4)
CSEM: 103380476 103389049(tcf4) 103398362(tcf12)
LCF: 108876745 108877764(tcf12) 108901150(tcf4)
SDU: 111218239(tcf12) 111221250(tcf4) 111229624
SLAL: 111650817(tcf12) 111659607(tcf4) 111666919
HCQ: 109507481 109525914(tcf12) 109529973(tcf4)
BPEC: 110169608 110172473(tcf4) 110175241(tcf12)
MALB: 109960770(tcf4) 109965935(tcf12) 109972491
ELS: 105016444(tcf12) 105018350 105020523(tcf4)
SFM: 108926742(tcf12) 108929064 108934374(tcf4)
PKI: 111843783(tcf4) 111845051(tcf12) 111846776
LCM: 102353644(TCF12) 102362134(TCF4)
CMK: 103184855(tcf4) 103187131(tcf12)
CIN: 778914(e12/e47)
APLC: 110977378
SKO: 100313756
DME: Dmel_CG5102(da)
DER: 6542377
DSE: 6611986
DSI: Dsimw501_GD23691(Dsim_GD23691)
DAN: 6498584
DSR: 110183272
DPE: 6589305
DMN: 108162477
DWI: 6649972
DAZ: 108611038
DNV: 108649668
DHE: 111594396
DVI: 6636637
MDE: 101890872
AAG: 5580046
AALB: 109416248
AME: 410553
BIM: 100746078
BTER: 100645175
CCAL: 108627858
OBB: 114880380
SOC: 105194232
MPHA: 105837269
AEC: 105143664
ACEP: 105627633
VEM: 105563276
HST: 105185406
DQU: 106743149
CFO: 105257493
LHU: 105671432
PGC: 109853506
OBO: 105274987
PCF: 106784185
NVI: 100120439
CSOL: 105366671
MDL: 103578529
TCA: 662057
DPA: 109544980
ATD: 109597457
BMOR: 101746894
BMAN: 114252596
PMAC: 106715612
PRAP: 110995940
HAW: 110376188
TNL: 113504282
PXY: 105392521
API: 100162653
DNX: 107167518
AGS: 114124861
RMD: 113557499
BTAB: 109041157
CLEC: 106672235
ZNE: 110836542
FCD: 110858316
PVM: 113817650
TUT: 107371392
DPTE: 113799664
CSCU: 111613818
CEL: CELE_M05B5.5(hlh-2)
CBR: CBG21941(Cbr-hlh-2)
BMY: Bm1_04725
TSP: Tsp_11731
PCAN: 112556359
CRG: 105345239
MYI: 110458725
OBI: 106868645
LAK: 106180233
SHX: MS3_00961
EGL: EGR_00950
NVE: 5512752
EPA: 110237604
ADF: 107352869
AMIL: 114962942
PDAM: 113674609
SPIS: 111335933
DGT: 114525520
HMG: 100202254
AQU: 100638509
 » show all
Reference
PMID:1681116
  Authors
Corneliussen B, Thornell A, Hallberg B, Grundstrom T
  Title
Helix-loop-helix transcriptional activators bind to a sequence in glucocorticoid response elements of retrovirus enhancers.
  Journal
J Virol 65:6084-93 (1991)
DOI:10.1128/JVI.65.11.6084-6093.1991
  Sequence
[hsa:6925]
Reference
PMID:1312219
  Authors
Hu JS, Olson EN, Kingston RE
  Title
HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors.
  Journal
Mol Cell Biol 12:1031-42 (1992)
DOI:10.1128/mcb.12.3.1031
  Sequence
[hsa:6938]
Reference
  Authors
Arce L, Yokoyama NN, Waterman ML
  Title
Diversity of LEF/TCF action in development and disease.
  Journal
Oncogene 25:7492-504 (2006)
DOI:10.1038/sj.onc.1210056

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