KEGG   ORTHOLOGY: K15646
Entry
K15646                      KO                                     

Name
cmaA
Definition
coronamic acid synthetase CmaA, adenylation and thiolation didomain protein [EC:6.2.1.46]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K15646  cmaA; coronamic acid synthetase CmaA, adenylation and thiolation didomain protein
Enzymes [BR:ko01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.46  L-allo-isoleucine---holo-[CmaA peptidyl-carrier protein] ligase
     K15646  cmaA; coronamic acid synthetase CmaA, adenylation and thiolation didomain protein
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  PKS-NRPS hybrid
   Bacterial type (modular)
    Coronatine hybrid PKS-NRPS
     K15646  cmaA; coronamic acid synthetase CmaA, adenylation and thiolation didomain protein
Other DBs
RN: R11084
Genes
PST: PSPTO_4709(cmaA)
PAMG: BKM19_029795
AZL: AZL_a01820
AG: AAQ93484(cmaA)
Reference
  Authors
Vaillancourt FH, Yeh E, Vosburg DA, O'Connor SE, Walsh CT
  Title
Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis.
  Journal
Nature 436:1191-4 (2005)
DOI:10.1038/nature03797
Reference
  Authors
Couch R, O'Connor SE, Seidle H, Walsh CT, Parry R
  Title
Characterization of CmaA, an adenylation-thiolation didomain enzyme involved in the biosynthesis of coronatine.
  Journal
J Bacteriol 186:35-42 (2004)
DOI:10.1128/JB.186.1.35-42.2004
  Sequence

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