Entry |
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Symbol |
cmaE
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Name |
coronamic acid synthetase CmaE, aminoacyltransferase [EC: 2.3.2.28]
|
Reaction |
R11103 | L-allo-isoleucyl-[peptidyl-carrier protein]:[peptidyl-carrier protein] L-allo-isoleucyltransferase |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K15647 cmaE; coronamic acid synthetase CmaE, aminoacyltransferase
Enzymes [BR:ko01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.28 L-allo-isoleucyltransferase
K15647 cmaE; coronamic acid synthetase CmaE, aminoacyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide synthase (PKS)
PKS-NRPS hybrid
Bacterial type (modular)
Coronatine hybrid PKS-NRPS
K15647 cmaE; coronamic acid synthetase CmaE, aminoacyltransferase
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Genes |
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Reference |
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Authors |
Vaillancourt FH, Yeh E, Vosburg DA, O'Connor SE, Walsh CT |
Title |
Cryptic chlorination by a non-haem iron enzyme during cyclopropyl amino acid biosynthesis. |
Journal |
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Sequence |
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Reference |
|
Authors |
Lai JR, Koglin A, Walsh CT |
Title |
Carrier protein structure and recognition in polyketide and nonribosomal peptide biosynthesis. |
Journal |
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Reference |
|
Authors |
Strieter ER, Vaillancourt FH, Walsh CT |
Title |
CmaE: a transferase shuttling aminoacyl groups between carrier protein domains in the coronamic acid biosynthetic pathway. |
Journal |
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Sequence |
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