KEGG   ORTHOLOGY: K15909Help
Entry
K15909                      KO                                     

Name
SHIP2, INPPL1
Definition
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86]
Pathway
ko00562  Inositol phosphate metabolism
ko01100  Metabolic pathways
ko04070  Phosphatidylinositol signaling system
ko04662  B cell receptor signaling pathway
ko04666  Fc gamma R-mediated phagocytosis
ko04910  Insulin signaling pathway
Disease
H01828  Opsismodysplasia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
 09150 Organismal Systems
  09151 Immune system
   04662 B cell receptor signaling pathway
    K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
   04666 Fc gamma R-mediated phagocytosis
    K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
  09152 Endocrine system
   04910 Insulin signaling pathway
    K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.86  phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase
     K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
Membrane trafficking [BR:ko04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Inositol 5-phosphatases
    K15909  SHIP2, INPPL1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2
BRITE hierarchy
Other DBs
RN: R09827
GO: 0034485
Genes
HSA: 3636(INPPL1)
PTR: 451403(INPPL1)
PPS: 100992766(INPPL1)
PON: 100450015(INPPL1)
MCC: 718421(INPPL1)
MMU: 16332(Inppl1)
RNO: 65038(Inppl1)
CFA: 485209(INPPL1)
AML: 100482460(INPPL1)
BTA: 783833(INPPL1)
SSC: 100462718(INPPL1)
ECB: 100066037(INPPL1)
MDO: 100015500(INPPL1)
OAA: 100088229(INPPL1)
GGA: 428692(INPPL1)
MGP: 100540799
TGU: 100222691
ACS: 100556812(inppl1)
XLA: 108698315 108708768(inppl1.L)
XTR: 100485745(inppl1)
DRE: 325179(inppl1a)
SPU: 584901
HMG: 100212864
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9660833
  Authors
Habib T, Hejna JA, Moses RE, Decker SJ
  Title
Growth factors and insulin stimulate tyrosine phosphorylation of the 51C/SHIP2 protein.
  Journal
J Biol Chem 273:18605-9 (1998)
DOI:10.1074/jbc.273.29.18605
  Sequence
[hsa:3636]

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