KEGG   ORTHOLOGY: K16007
Entry
K16007            Tight     KO                                     

Name
oleAI
Definition
8,8a-deoxyoleandolide synthase 1
Pathway
ko00522  Biosynthesis of 12-, 14- and 16-membered macrolides
ko01052  Type I polyketide structures
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00775  Oleandomycin biosynthesis, malonyl-CoA + methylmalonyl-CoA => 8,8a-deoxyoleandolide => oleandomycin
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16007  oleAI; 8,8a-deoxyoleandolide synthase 1
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K16007  oleAI; 8,8a-deoxyoleandolide synthase 1
Other DBs
RN: R06453
Genes
AG: AAF82408(oleAI)
Reference
  Authors
Shah S, Xue Q, Tang L, Carney JR, Betlach M, McDaniel R
  Title
Cloning, characterization and heterologous expression of a polyketide synthase and P-450 oxidase involved in the biosynthesis of the antibiotic oleandomycin.
  Journal
J Antibiot (Tokyo) 53:502-8 (2000)
DOI:10.7164/antibiotics.53.502
  Sequence

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