KEGG   ORTHOLOGY: K16015
Entry
K16015                      KO                                     

Name
rifL, asm44
Definition
oxidoreductase [EC:1.1.1.-]
Pathway
ko01051  Biosynthesis of ansamycins
ko01110  Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01051 Biosynthesis of ansamycins
    K16015  rifL, asm44; oxidoreductase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.-  
     K16015  rifL, asm44; oxidoreductase
Other DBs
RN: R06594
Genes
SVL: Strvi_5369
SRC: M271_45555
SPAD: DVK44_17995
FRA: Francci3_0430
FRE: Franean1_1660 Franean1_4840
FAL: FRAAL0915
SEN: SACE_2871(rifL)
AMD: AMED_0628(rifL)
AMN: RAM_03210
AMM: AMES_0626(rifL)
AMZ: B737_0627(rifL)
AMI: Amir_3288
SAQ: Sare_1256
MIL: ML5_5913
MSAG: GCM10017556_49870(rifL)
 » show all
Reference
  Authors
Yu TW, Muller R, Muller M, Zhang X, Draeger G, Kim CG, Leistner E, Floss HG
  Title
Mutational analysis and reconstituted expression of the biosynthetic genes involved in the formation of 3-amino-5-hydroxybenzoic acid, the starter unit of rifamycin biosynthesis in amycolatopsis Mediterranei S699.
  Journal
J Biol Chem 276:12546-55 (2001)
DOI:10.1074/jbc.M009667200
  Sequence
[amn:RAM_03210]
Reference
  Authors
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG
  Title
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.
  Journal
Proc Natl Acad Sci U S A 99:7968-73 (2002)
DOI:10.1073/pnas.092697199

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