KEGG   ORTHOLOGY: K16058
Entry
K16058                      KO                                     
Symbol
ORAI3
Name
calcium release-activated calcium channel protein 3
Pathway
map04020  Calcium signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K16058  ORAI3; calcium release-activated calcium channel protein 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K16058  ORAI3; calcium release-activated calcium channel protein 3
Ion channels [BR:ko04040]
 Other channels
  Calcium channel, calcium release-activated (Orai)
   K16058  ORAI3; calcium release-activated calcium channel protein 3
Other DBs
TC: 1.A.52.1.2
Genes
HSA: 93129(ORAI3)
PTR: 454057(ORAI3)
PPS: 100972631(ORAI3)
PON: 100460568(ORAI3)
NLE: 100589927(ORAI3)
MCC: 712360(ORAI3)
MCF: 102131759(ORAI3)
CSAB: 103231138(ORAI3)
CATY: 105599342(ORAI3)
PANU: 101022317(ORAI3)
TGE: 112614148(ORAI3)
RRO: 104661558(ORAI3)
RBB: 108530460(ORAI3)
TFN: 117087680(ORAI3)
PTEH: 111525720(ORAI3)
CJC: 100415275(ORAI3)
SBQ: 101043870(ORAI3)
CSYR: 103264383(ORAI3)
MMUR: 105871056(ORAI3)
OGA: 100945281(ORAI3)
MMU: 269999(Orai3)
MCAL: 110297805(Orai3)
MPAH: 110317706(Orai3)
RNO: 309000(Orai3)
MCOC: 116103033(Orai3)
MUN: 110559778 110559791
CGE: 100753665(Orai3)
PLEU: 114704390(Orai3)
NGI: 103726337(Orai3)
HGL: 101705579(Orai3)
CPOC: 100715641(Orai3)
CCAN: 109682445(Orai3)
DORD: 105981835(Orai3)
DSP: 122096242(Orai3)
NCAR: 124970056
OCU: 100342751(ORAI3)
OPI: 101519686(ORAI3)
TUP: 102493634(ORAI3)
CFA: 607303(ORAI3)
VVP: 112929255(ORAI3)
VLG: 121487500(ORAI3)
AML: 100477490(ORAI3)
UMR: 103657878(ORAI3)
UAH: 113267708(ORAI3)
UAR: 123784666(ORAI3)
ELK: 111162183
LLV: 125091093
MPUF: 101681327(ORAI3)
ORO: 101376699(ORAI3)
EJU: 114214334(ORAI3)
ZCA: 113933096(ORAI3)
MLX: 117999577(ORAI3)
FCA: 101091330(ORAI3)
PYU: 121022172(ORAI3)
PBG: 122471430(ORAI3)
PTG: 102961617(ORAI3)
PPAD: 109259030(ORAI3)
AJU: 106979111(ORAI3)
HHV: 120242292(ORAI3)
BTA: 515971(ORAI3)
BOM: 102275553(ORAI3)
BIU: 109578148(ORAI3)
BBUB: 102400065(ORAI3)
CHX: 102175544(ORAI3)
OAS: 101105211(ORAI3)
ODA: 120877584(ORAI3)
CCAD: 122432975(ORAI3)
SSC: 100736565(ORAI3)
CFR: 102516780(ORAI3)
CBAI: 105082786(ORAI3)
CDK: 105102722(ORAI3)
VPC: 102525262(ORAI3)
BACU: 102999297(ORAI3)
LVE: 103080019(ORAI3)
OOR: 101282308(ORAI3)
DLE: 111182128(ORAI3)
PCAD: 102980350(ORAI3)
PSIU: 116740364(ORAI3)
ECB: 100063559(ORAI3)
EPZ: 103547235(ORAI3)
EAI: 106831896(ORAI3)
MYB: 102252561(ORAI3)
MYD: 102774046(ORAI3)
MMYO: 118656657(ORAI3)
MNA: 107540810(ORAI3)
PKL: 118704855(ORAI3)
HAI: 109374195(ORAI3)
DRO: 112304795(ORAI3)
AJM: 119041170(ORAI3)
PDIC: 114511815(ORAI3)
PHAS: 123825681(ORAI3)
MMF: 118642748(ORAI3)
RFQ: 117019836(ORAI3)
PALE: 102884414(ORAI3)
PGIG: 120620068(ORAI3)
PVP: 105304518(ORAI3)
RAY: 107503988(ORAI3)
MJV: 108385474(ORAI3)
TOD: 119241719(ORAI3)
SARA: 101547979(ORAI3)
LAV: 100662323(ORAI3)
TMU: 101354119
DNM: 101441915(ORAI3)
MDO: 100013345(ORAI3)
GAS: 123254349(ORAI3)
SHR: 100929039(ORAI3)
PCW: 110223125(ORAI3)
OAA: 100082960(ORAI3)
PSS: 102460868(ORAI3)
CPIC: 101935918(ORAI3)
CABI: 116815509(ORAI3)
MRV: 120403329(ORAI3)
ACS: 100554630(orai3)
PBI: 103054285
PGUT: 117666838(ORAI3)
PMUA: 114582852(ORAI3)
GJA: 107106650(ORAI3)
 » show all
Reference
PMID:21987805
  Authors
Demuro A, Penna A, Safrina O, Yeromin AV, Amcheslavsky A, Cahalan MD, Parker I
  Title
Subunit stoichiometry of human Orai1 and Orai3 channels in closed and open states.
  Journal
Proc Natl Acad Sci U S A 108:17832-7 (2011)
DOI:10.1073/pnas.1114814108
Reference
PMID:19622606
  Authors
Mignen O, Thompson JL, Shuttleworth TJ
  Title
The molecular architecture of the arachidonate-regulated Ca2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits.
  Journal
J Physiol 587:4181-97 (2009)
DOI:10.1113/jphysiol.2009.174193
Reference
PMID:22993197
  Authors
Motiani RK, Zhang X, Harmon KE, Keller RS, Matrougui K, Bennett JA, Trebak M
  Title
Orai3 is an estrogen receptor alpha-regulated Ca(2)(+) channel that promotes tumorigenesis.
  Journal
FASEB J 27:63-75 (2013)
DOI:10.1096/fj.12-213801
  Sequence
[hsa:93129]

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Ontology (3)   
   KEGG BRITE (2)   
   TC (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Gene (154)   
   KEGG GENES (118)   
   KEGG MGENES (16)   
   RefGene (19)   
   OC (1)   
Literature (3)   
   PubMed (3)   
All databases (162)   

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