KEGG   ORTHOLOGY: K16058
Entry
K16058                      KO                                     
Symbol
ORAI3
Name
calcium release-activated calcium channel protein 3
Pathway
map04020  Calcium signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K16058  ORAI3; calcium release-activated calcium channel protein 3
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels
    K16058  ORAI3; calcium release-activated calcium channel protein 3
Ion channels [BR:ko04040]
 Other channels
  Calcium channel, calcium release-activated (Orai)
   K16058  ORAI3; calcium release-activated calcium channel protein 3
Other DBs
TC: 1.A.52.1.2
Genes
HSA: 93129(ORAI3)
PTR: 454057(ORAI3)
PPS: 100972631(ORAI3)
PON: 100460568(ORAI3)
NLE: 100589927(ORAI3)
MCC: 712360(ORAI3)
MCF: 102131759(ORAI3)
CSAB: 103231138(ORAI3)
CATY: 105599342(ORAI3)
PANU: 101022317(ORAI3)
TGE: 112614148(ORAI3)
RRO: 104661558(ORAI3)
RBB: 108530460(ORAI3)
TFN: 117087680(ORAI3)
PTEH: 111525720(ORAI3)
CJC: 100415275(ORAI3)
SBQ: 101043870(ORAI3)
CSYR: 103264383(ORAI3)
MMUR: 105871056(ORAI3)
OGA: 100945281(ORAI3)
MMU: 269999(Orai3)
MCAL: 110297805(Orai3)
MPAH: 110317706(Orai3)
RNO: 309000(Orai3)
MCOC: 116103033(Orai3)
CGE: 100753665(Orai3)
PLEU: 114704390(Orai3)
NGI: 103726337(Orai3)
HGL: 101705579(Orai3)
CPOC: 100715641(Orai3)
CCAN: 109682445(Orai3)
DORD: 105981835(Orai3)
DSP: 122096242(Orai3)
NCAR: 124970056
OCU: 100342751(ORAI3)
OPI: 101519686(ORAI3)
TUP: 102493634(ORAI3)
CFA: 607303(ORAI3)
VVP: 112929255(ORAI3)
VLG: 121487500(ORAI3)
AML: 100477490(ORAI3)
UMR: 103657878(ORAI3)
UAH: 113267708(ORAI3)
UAR: 123784666(ORAI3)
ELK: 111162183
LLV: 125091093
MPUF: 101681327(ORAI3)
ORO: 101376699(ORAI3)
EJU: 114214334(ORAI3)
ZCA: 113933096(ORAI3)
MLX: 117999577(ORAI3)
FCA: 101091330(ORAI3)
PYU: 121022172(ORAI3)
PBG: 122471430(ORAI3)
PTG: 102961617(ORAI3)
PPAD: 109259030(ORAI3)
AJU: 106979111(ORAI3)
HHV: 120242292(ORAI3)
BTA: 515971(ORAI3)
BOM: 102275553(ORAI3)
BIU: 109578148(ORAI3)
BBUB: 102400065(ORAI3)
CHX: 102175544(ORAI3)
OAS: 101105211(ORAI3)
ODA: 120877584(ORAI3)
CCAD: 122432975(ORAI3)
SSC: 100736565(ORAI3)
CFR: 102516780(ORAI3)
CBAI: 105082786(ORAI3)
CDK: 105102722(ORAI3)
VPC: 102525262(ORAI3)
BACU: 102999297(ORAI3)
LVE: 103080019(ORAI3)
OOR: 101282308(ORAI3)
DLE: 111182128(ORAI3)
PCAD: 102980350(ORAI3)
PSIU: 116740364(ORAI3)
ECB: 100063559(ORAI3)
EPZ: 103547235(ORAI3)
EAI: 106831896(ORAI3)
MYB: 102252561(ORAI3)
MYD: 102774046(ORAI3)
MMYO: 118656657(ORAI3)
MNA: 107540810(ORAI3)
PKL: 118704855(ORAI3)
HAI: 109374195(ORAI3)
DRO: 112304795(ORAI3)
AJM: 119041170(ORAI3)
PDIC: 114511815(ORAI3)
PHAS: 123825681(ORAI3)
MMF: 118642748(ORAI3)
RFQ: 117019836(ORAI3)
PALE: 102884414(ORAI3)
PGIG: 120620068(ORAI3)
PVP: 105304518(ORAI3)
RAY: 107503988(ORAI3)
MJV: 108385474(ORAI3)
TOD: 119241719(ORAI3)
SARA: 101547979(ORAI3)
LAV: 100662323(ORAI3)
TMU: 101354119
DNM: 101441915(ORAI3)
MDO: 100013345(ORAI3)
GAS: 123254349(ORAI3)
SHR: 100929039(ORAI3)
PCW: 110223125(ORAI3)
OAA: 100082960(ORAI3)
PSS: 102460868(ORAI3)
CPIC: 101935918(ORAI3)
CABI: 116815509(ORAI3)
MRV: 120403329(ORAI3)
ACS: 100554630(orai3)
PBI: 103054285
PGUT: 117666838(ORAI3)
PMUA: 114582852(ORAI3)
GJA: 107106650(ORAI3)
 » show all
Reference
  Authors
Demuro A, Penna A, Safrina O, Yeromin AV, Amcheslavsky A, Cahalan MD, Parker I
  Title
Subunit stoichiometry of human Orai1 and Orai3 channels in closed and open states.
  Journal
Proc Natl Acad Sci U S A 108:17832-7 (2011)
DOI:10.1073/pnas.1114814108
Reference
  Authors
Mignen O, Thompson JL, Shuttleworth TJ
  Title
The molecular architecture of the arachidonate-regulated Ca2+-selective ARC channel is a pentameric assembly of Orai1 and Orai3 subunits.
  Journal
J Physiol 587:4181-97 (2009)
DOI:10.1113/jphysiol.2009.174193
Reference
  Authors
Motiani RK, Zhang X, Harmon KE, Keller RS, Matrougui K, Bennett JA, Trebak M
  Title
Orai3 is an estrogen receptor alpha-regulated Ca(2)(+) channel that promotes tumorigenesis.
  Journal
FASEB J 27:63-75 (2013)
DOI:10.1096/fj.12-213801
  Sequence
[hsa:93129]

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