KEGG   ORTHOLOGY: K16060
Entry
K16060                      KO                                     
Symbol
BIRC2_3
Name
baculoviral IAP repeat-containing protein 2/3
Pathway
map01524  Platinum drug resistance
map04064  NF-kappa B signaling pathway
map04120  Ubiquitin mediated proteolysis
map04210  Apoptosis
map04215  Apoptosis - multiple species
map04217  Necroptosis
map04390  Hippo signaling pathway
map04510  Focal adhesion
map04621  NOD-like receptor signaling pathway
map04624  Toll and Imd signaling pathway
map04668  TNF signaling pathway
map05132  Salmonella infection
map05145  Toxoplasmosis
map05168  Herpes simplex virus 1 infection
map05200  Pathways in cancer
map05202  Transcriptional misregulation in cancer
map05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04064 NF-kappa B signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04668 TNF signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04215 Apoptosis - multiple species
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04217 Necroptosis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09150 Organismal Systems
  09151 Immune system
   04624 Toll and Imd signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   04621 NOD-like receptor signaling pathway
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
   05202 Transcriptional misregulation in cancer
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
Peptidases and inhibitors [BR:ko01002]
 Peptidase inhibitors
  Family I32: IAP family
   K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    K16060  BIRC2_3; baculoviral IAP repeat-containing protein 2/3
Other DBs
GO: 0043027
Genes
HSA: 329(BIRC2) 330(BIRC3)
PTR: 451507(BIRC3) 451508(BIRC2)
PPS: 100970636(BIRC2) 100971429(BIRC3)
GGO: 101126938(BIRC3) 101127675(BIRC2)
PON: 100457249(BIRC3) 100457858(BIRC2)
NLE: 100579740(BIRC3) 100580307(BIRC2)
MCC: 702468(BIRC3) 702592(BIRC2)
MCF: 102137780 102138168(BIRC2)
CSAB: 103248332(BIRC3) 103248333(BIRC2)
CATY: 105591400(BIRC3) 105591401(BIRC2)
PANU: 100997299(BIRC3) 101026503(BIRC2)
TGE: 112605791(BIRC2) 112605792(BIRC3)
RRO: 104674657(BIRC3) 104674658(BIRC2)
RBB: 108514076(BIRC2) 108514077(BIRC3)
TFN: 117080066(BIRC3) 117080067(BIRC2)
PTEH: 111540065(BIRC3) 111540066
CJC: 100394418(BIRC2)
SBQ: 101027816(BIRC2) 101043827(BIRC3)
CSYR: 103251545(BIRC3) 103251546
MMUR: 105874569(BIRC2) 105874570(BIRC3)
LCAT: 123641896(BIRC2) 123641897(BIRC3)
OGA: 100950019(BIRC2) 100951387(BIRC3) 100951719
MMU: 11796(Birc3) 11797(Birc2)
MCAL: 110301861(Birc2) 110302303
RNO: 60371(Birc2) 78971(Birc3)
MUN: 110553751(Birc3) 110553757
CGE: 100756596(Birc2) 100761700
MAUA: 101835694(Birc2) 110339912
AAMP: 119809564 119809632(Birc2)
NGI: 103731538(Birc2) 103746493(Birc3)
HGL: 101718804(Birc2) 101719143(Birc3)
CPOC: 100713574(Birc3) 100715527(Birc2)
CCAN: 109689097(Birc2) 109689098(Birc3)
DORD: 105980764(Birc2)
DSP: 122110391(Birc2)
OCU: 100338118(BIRC2) 100340120(BIRC3)
OPI: 101526404(BIRC2) 101529445(BIRC3)
TUP: 102493795(BIRC2) 102494213(BIRC3)
CFA: 479464(BIRC2) 489433(BIRC3)
CLUD: 112671444(BIRC2) 112671445
VVP: 112925935(BIRC3) 112925936(BIRC2)
VLG: 121500037(BIRC2) 121500437
UMR: 103662462(BIRC2) 103662463
UAH: 113260143(BIRC2) 113260144
UAR: 123792498 123792499(BIRC2)
MPUF: 101691821(BIRC2) 101692293
ORO: 101372845(BIRC3) 101373139(BIRC2)
EJU: 114211382
MLX: 118013143(BIRC3) 118013146(BIRC2)
FCA: 101083444 101101663(BIRC2)
PYU: 121020751 121020801(BIRC2)
PBG: 122482885 122482886(BIRC2)
PTG: 102951731(BIRC3) 102972419(BIRC2)
PPAD: 109257521 109257526(BIRC2)
AJU: 106976507 106976508(BIRC2)
HHV: 120219677 120219681(BIRC2)
BTA: 514386(BIRC3) 539314(BIRC2)
BOM: 102269806(BIRC3) 102286771(BIRC2)
BIU: 109555878 109568764(BIRC3) 109569840(BIRC2)
BBUB: 102394110(BIRC3) 102394850
CHX: 102173485(BIRC2) 102173952(BIRC3)
OAS: 101119930(BIRC2) 101120189(BIRC3)
ODA: 120876161(BIRC2) 120876162(BIRC3)
CCAD: 122449723(BIRC2) 122449787(BIRC3)
SSC: 100622590(BIRC3) 100622859
CFR: 102513751 102513991(BIRC2)
CBAI: 105083471(BIRC2) 105083472(BIRC3)
CDK: 105087177(BIRC2) 105087178(BIRC3)
VPC: 102530205(BIRC2) 102539995(BIRC3)
BACU: 103006934(BIRC3) 103007434(BIRC2)
LVE: 103086871(BIRC3) 103087142(BIRC2)
OOR: 101276394(BIRC3) 101276649(BIRC2)
DLE: 111168369(BIRC2) 111168370(BIRC3)
PCAD: 102981700(BIRC3) 102981991(BIRC2)
PSIU: 116757989(BIRC3) 116758079(BIRC2)
ECB: 100061273(BIRC2) 100068894(BIRC3)
EPZ: 103552625(BIRC3) 103552627(BIRC2)
EAI: 106845876(BIRC3) 106845877(BIRC2)
MYB: 102240943(BIRC3) 102241248(BIRC2)
MYD: 102771967(BIRC2) 102772449(BIRC3)
MLF: 102424316(BIRC3) 102424628(BIRC2)
MNA: 107532417(BIRC2) 107532418
PKL: 118712461(BIRC2)
SHON: 118975660(BIRC2) 118975664
AJM: 119054065(BIRC3) 119054066(BIRC2)
PDIC: 114498544(BIRC2) 114500581(BIRC3)
PHAS: 123805465(BIRC2) 123805489(BIRC3)
MMF: 118627996(BIRC2) 118628047
RFQ: 117030524(BIRC2) 117030766(BIRC3)
PALE: 102884388 102884651(BIRC2)
PGIG: 120618083(BIRC3) 120618084(BIRC2)
PVP: 105298277(BIRC3) 105298278(BIRC2)
RAY: 107504640 107504641(BIRC2)
MJV: 108389053(BIRC3) 108389075(BIRC2)
TOD: 119240918(BIRC2) 119240919(BIRC3)
SARA: 101546184(BIRC2) 101546443(BIRC3)
DNM: 101427801(BIRC3) 101428234
MDO: 100010741 100010782(BIRC2)
OAA: 100077243
GGA: 374012(BIRC2)
PCOC: 116230614(BIRC2)
MGP: 100543708(BIRC2)
CJO: 107308397(BIRC2)
NMEL: 110389900(BIRC2)
APLA: 101793263(BIRC2)
ACYG: 106034170(BIRC2)
AFUL: 116491707
TGU: 100225317(BIRC2)
LSR: 110470015
SCAN: 103827281
PMOA: 120506584
OTC: 121342542
PRUF: 121364160
GFR: 102031819
FAB: 101821374(BIRC2)
PHI: 102110239(BIRC2)
PMAJ: 107210777(BIRC2)
CCAE: 111924350(BIRC2)
CCW: 104690066
CBRC: 103617954
ETL: 114067044(BIRC2)
ZAB: 102070517(BIRC2)
FPG: 101924079(BIRC2)
FCH: 102051620(BIRC2)
CLV: 102090342
EGZ: 104128906(BIRC2)
NNI: 104023072(BIRC2)
PLET: 104619554
PCRI: 104024478(BIRC2)
ACUN: 113491430
TALA: 104359443
PADL: 103918923(BIRC2)
ACHC: 115353209
HALD: 104325606(BIRC2)
CCRI: 104168972(BIRC2)
CSTI: 104549733
EHS: 104516561
FGA: 104070819
GSTE: 104260222
LDI: 104340321(BIRC2)
MNB: 103777881(BIRC2)
AAM: 106495530(BIRC2)
AROW: 112971955(BIRC2)
NPD: 112943708(BIRC2)
DNE: 112988747(BIRC2)
ASN: 102368067
AMJ: 102562735(BIRC2)
CPOO: 109306739
GGN: 109303136
PSS: 102448753
CMY: 102941252
CPIC: 101948146
TST: 117871179
CABI: 116814900(BIRC2)
MRV: 120371556(BIRC2)
ACS: 100554030(birc2)
PVT: 110080243(BIRC2)
SUND: 121927176(BIRC2)
PBI: 103052845(BIRC2)
PMUR: 107286355
TSR: 106549668
PGUT: 117660822(BIRC2)
VKO: 123029249
PMUA: 114595659(BIRC2)
ZVI: 118084907(BIRC2)
STOW: 125430428(BIRC2)
XLA: 100036859(birc2.S) 108703748 446568(birc2.L)
XTR: 108648784 448041(birc2)
NPR: 108786933
RTEM: 120929024(BIRC2)
BBUF: 120996399(BIRC2)
BGAR: 122931187(BIRC2)
DRE: 373107(birc2)
PPRM: 120494429(birc2)
MAMB: 125253483(birc2)
IPU: 100304597(birc2)
PHYP: 113541487(birc2)
SMEO: 124397708(birc2)
TFD: 113634941(birc2)
AMEX: 103025481(birc2)
EEE: 113573611(birc2)
TRU: 101075537
LCO: 104934542
NCC: 104964663(birc2)
CGOB: 115019094
ELY: 117266679(birc2)
EFO: 125898103(birc2)
PLEP: 121952415(birc2)
SLUC: 116056492 116064779(birc2)
ECRA: 117955162(birc2)
PFLV: 114566357
GAT: 120821377(birc2)
PPUG: 119215054(birc2)
MSAM: 119884738(birc2)
CUD: 121518456(birc2)
ALAT: 119030723(birc2)
MZE: 101484124
ONL: 100705328
OAU: 116313607(birc2)
OLA: 101172600
OML: 112142434(birc2)
XMA: 102228638(birc2)
XCO: 114153415(birc2)
XHE: 116728331
PRET: 103475480(birc2)
PFOR: 103140982(birc2)
PLAI: 106955041(birc2)
PMEI: 106921217(birc2)
GAF: 122844404(birc2)
CVG: 107098510(birc2)
CTUL: 119775863(birc2)
GMU: 124876393(birc2)
NFU: 107387009(birc2)
KMR: 108237026(birc2)
ALIM: 106514085(birc2)
NWH: 119420583(birc2)
AOCE: 111580650
MCEP: 125021342(birc2)
CSEM: 103395117(birc2)
POV: 109628681
SSEN: 122779604(birc2)
HHIP: 117774164(birc2)
HSP: 118122602(birc2)
LCF: 108893387
SDU: 111234415
SLAL: 111666176
XGL: 120802962(birc2)
HCQ: 109509764
BPEC: 110158425
MALB: 109959278
BSPL: 114869611(birc2)
OMY: 110514649(birc2) 110533228
ONE: 115121787
SALP: 112072902
SNH: 120042228(birc2)
ELS: 105006427(birc2)
SFM: 108934246
PKI: 111838067
AANG: 118236782(birc2)
LOC: 102688292(birc2)
PSPA: 121302550(birc2)
LCM: 102364182(BIRC2)
CMK: 103177430(birc2)
RTP: 109939041
CIN: 100175293 100182621 100183688 778881(zf(ring)-14)
SPU: 581540
APLC: 110981472
SKO: 100378904
DME: Dmel_CG8293(Diap2)
DER: 6548868
DSE: 6609342
DSI: Dsimw501_GD25587(Dsim_GD25587)
DYA: Dyak_GE14118(Dyak_Iap2)
DAN: 6496179
DSR: 110178237
DPO: 4805563
DPE: 6603157
DWI: 6640629
DGR: 6560519
DAZ: 108617526
DNV: 108653986
DHE: 111599683
DVI: 6627156
CCAT: 101452029
BOD: 106617867
MDE: 101900624
SCAC: 106092843
LSQ: 119609773
HIS: 119654977
AAG: 5568196
AALB: 109402332
CPII: 120421687
CNS: 116345598
BCOO: 119070662
AME: 413374
ACER: 108003619
ALAB: 122720794
BIM: 100741028
BBIF: 117211555
BVK: 117237956
BVAN: 117155194
BTER: 100647366
BPYO: 122570199
OBB: 114879108
MGEN: 117229145
CGIG: 122399863
SOC: 105199677
MPHA: 105829200
AEC: 105148032
ACEP: 105623438
PBAR: 105422658
VEM: 105567055
HST: 105182143
DQU: 106751808
CFO: 105249204
FEX: 115241158
LHU: 105676081
OBO: 105282023
PCF: 106791785
PFUC: 122515694
VPS: 122635270
NVI: 100122438
CSOL: 105359266
TPRE: 106653765
CGLO: 123259502
FAS: 105263674
DAM: 107036657
AGIF: 122857990
CCIN: 107269892
TCA: 663905(Tiap2)
DPA: 109534605
SOY: 115891591
ATD: 109596674
CSET: 123318977
AGB: 108910197
LDC: 111510610
NVL: 108568147
APLN: 108741011
PPYR: 116164134
OTU: 111416078
BMOR: 100529214(iap2)
BMAN: 114245563
BANY: 112045716
PMAC: 106714052
PPOT: 106103068
PXU: 106121999
PRAP: 110993152
ZCE: 119833833
HAW: 110383246
TNL: 113498337
SLIU: 111357679
API: 100159034
RMD: 113556228
DCI: 103508496
CLEC: 106669703
HHAL: 106690100
NLU: 111061132
FOC: 113211278
TPAL: 117652864
ZNE: 110838931
CSEC: 111866121
HAME: 121856695
EAF: 111702197
LSM: 121117438
PPOI: 119099845
DSV: 119461566
RSAN: 119395929
RMP: 119174266
CSCU: 111635727
PTEP: 107447772
SDM: 118188688
NVE: 5501165
EPA: 110251845
ATEN: 116286304
ADF: 107347984
AMIL: 114959586
PDAM: 113672022
SPIS: 111334213
DGT: 114536589
XEN: 124441476
 » show all
Reference
PMID:8643514
  Authors
Uren AG, Pakusch M, Hawkins CJ, Puls KL, Vaux DL
  Title
Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors.
  Journal
Proc Natl Acad Sci U S A 93:4974-8 (1996)
DOI:10.1073/pnas.93.10.4974
  Sequence
[hsa:329 330]
Reference
  Authors
Dubrez-Daloz L, Dupoux A, Cartier J
  Title
IAPs: more than just inhibitors of apoptosis proteins.
  Journal
Cell Cycle 7:1036-46 (2008)
DOI:10.4161/cc.7.8.5783

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