KEGG   ORTHOLOGY: K16184
Entry
K16184                      KO                                     

Name
AKT1S1, PRAS40
Definition
proline-rich AKT1 substrate 1
Pathway
ko04140  Autophagy - animal
ko04150  mTOR signaling pathway
ko04152  AMPK signaling pathway
ko04211  Longevity regulating pathway
ko04213  Longevity regulating pathway - multiple species
ko04714  Thermogenesis
ko05131  Shigellosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
   04150 mTOR signaling pathway
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
 09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
   04213 Longevity regulating pathway - multiple species
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
  09159 Environmental adaptation
   04714 Thermogenesis
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05131 Shigellosis
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
Membrane trafficking [BR:ko04131]
 Autophagy
  Other autophagy associated proteins
   mTORC1 complex
    K16184  AKT1S1, PRAS40; proline-rich AKT1 substrate 1
Genes
HSA: 84335(AKT1S1)
PTR: 456218(AKT1S1)
PPS: 100981524(AKT1S1)
GGO: 101151809(AKT1S1)
PON: 100449244(AKT1S1)
NLE: 100606336(AKT1S1)
MCC: 719101(AKT1S1)
MCF: 102139860(AKT1S1)
CSAB: 103235060(AKT1S1)
RRO: 104667216(AKT1S1)
RBB: 108535813(AKT1S1)
CJC: 100385926(AKT1S1)
SBQ: 101035426(AKT1S1)
MMU: 67605(Akt1s1)
MCAL: 110299208(Akt1s1)
MPAH: 110324411(Akt1s1)
RNO: 292887(Akt1s1)
CGE: 100768286(Akt1s1)
NGI: 103743684(Akt1s1)
HGL: 101712955(Akt1s1)
CCAN: 109683918(Akt1s1)
TUP: 102485528(AKT1S1)
CFA: 610130(AKT1S1)
VVP: 112931404(AKT1S1)
AML: 109489401(AKT1S1)
UMR: 103657265(AKT1S1)
UAH: 113243278(AKT1S1)
ORO: 101366130(AKT1S1)
ELK: 111160809
FCA: 101100932(AKT1S1)
PPAD: 109253038(AKT1S1)
AJU: 106983118(AKT1S1)
BTA: 514859(AKT1S1)
BOM: 102264796(AKT1S1)
BIU: 109572134(AKT1S1)
BBUB: 102395301(AKT1S1)
CHX: 102186333(AKT1S1)
OAS: 101109114(AKT1S1)
SSC: 100519715(AKT1S1)
CFR: 102515969(AKT1S1)
CDK: 105100186(AKT1S1)
BACU: 103005941(AKT1S1)
LVE: 103075856(AKT1S1)
OOR: 101289949(AKT1S1)
DLE: 111180592(AKT1S1)
PCAD: 102990917(AKT1S1)
ECB: 100052282(AKT1S1)
EPZ: 103558294(AKT1S1)
EAI: 106824154(AKT1S1)
MYB: 102243802(AKT1S1)
MYD: 102758931(AKT1S1)
MNA: 107531871(AKT1S1)
HAI: 109391032(AKT1S1)
DRO: 112310069(AKT1S1)
PALE: 102897877(AKT1S1)
RAY: 107498836(AKT1S1)
MJV: 108383352(AKT1S1)
LAV: 100671446(AKT1S1)
TMU: 101345300
MDO: 100030158(AKT1S1)
SHR: 100928550(AKT1S1)
PCW: 110219791(AKT1S1)
OAA: 114814792(AKT1S1)
ASN: 102367984(AKT1S1)
AMJ: 102558199(AKT1S1)
CPIC: 101938133(AKT1S1)
ACS: 100557925(akt1s1)
PVT: 110078574(AKT1S1)
PBI: 103049186(AKT1S1)
TSR: 106549271(AKT1S1) 106556088
PMUA: 114608013(AKT1S1)
GJA: 107116605(AKT1S1)
XLA: 431814(akt1s1.S) 495075(akt1s1.L)
XTR: 496515(akt1s1)
NPR: 108792627(AKT1S1)
DRE: 566559(akt1s1)
CCAR: 109109154
IPU: 108280807(akt1s1)
PHYP: 113528230(akt1s1)
AMEX: 111193360(akt1s1)
EEE: 113587138(akt1s1)
LCO: 104939070(akt1s1)
NCC: 104954396(akt1s1)
MZE: 101481934(akt1s1)
ONL: 100689736(akt1s1)
OLA: 101169289(akt1s1)
XMA: 102221079(akt1s1)
XCO: 114159983(akt1s1)
PRET: 103468981(akt1s1)
CVG: 107097127(akt1s1)
NFU: 107378483(akt1s1)
KMR: 108237767(akt1s1)
AOCE: 111572742(akt1s1)
CSEM: 103392853(akt1s1)
POV: 109634335(akt1s1)
LCF: 108880633(akt1s1)
SDU: 111217583(akt1s1)
SLAL: 111660518(akt1s1)
HCQ: 109527791(akt1s1)
BPEC: 110161314(akt1s1)
MALB: 109963177(akt1s1)
OTW: 112258995
ELS: 105012938(akt1s1)
SFM: 108941800(akt1s1)
PKI: 111836870(akt1s1)
LCM: 102354837(AKT1S1)
CMK: 103173667(akt1s1)
RTP: 109923030(akt1s1)
BFO: 118412296
CIN: 100176540
APLC: 110975487
SKO: 100379062
AME: 551512
BIM: 100746742
BTER: 100645428
CCAL: 108622323
OBB: 114874712
SOC: 105198761
ACEP: 105618850
PBAR: 105427247
HST: 105189811
DQU: 106747449
CFO: 105249652
LHU: 105673603
PGC: 109853289
NVI: 100217361(Lobe)
CSOL: 105365101
NVL: 108559757
BTAB: 109043844
CLEC: 106669992
TUT: 107362660
PTEP: 107444734
MYI: 110449090
OBI: 106873180
NVE: 5508361
EPA: 110245043
AMIL: 114958534
SPIS: 111326006
DGT: 114533702
HMG: 100206382
 » show all
Reference
  Authors
Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM
  Title
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
  Journal
Mol Cell 25:903-15 (2007)
DOI:10.1016/j.molcel.2007.03.003
Reference
  Authors
Kovacina KS, Park GY, Bae SS, Guzzetta AW, Schaefer E, Birnbaum MJ, Roth RA
  Title
Identification of a proline-rich Akt substrate as a 14-3-3 binding partner.
  Journal
J Biol Chem 278:10189-94 (2003)
DOI:10.1074/jbc.M210837200
  Sequence
[hsa:84335]

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