KEGG   ORTHOLOGY: K16333
Entry
K16333                      KO                                     
Symbol
CRTC2, TORC2
Name
CREB-regulated transcription coactivator 2
Pathway
map04151  PI3K-Akt signaling pathway
map04152  AMPK signaling pathway
map04922  Glucagon signaling pathway
map04931  Insulin resistance
map05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
   04152 AMPK signaling pathway
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    K16333  CRTC2, TORC2; CREB-regulated transcription coactivator 2
Genes
HSA: 200186(CRTC2)
PTR: 738694(CRTC2)
PPS: 100976458(CRTC2)
GGO: 101149666(CRTC2)
PON: 100438416(CRTC2)
NLE: 100597840(CRTC2)
MCC: 715908(CRTC2)
MCF: 102137277(CRTC2)
CSAB: 103223939(CRTC2)
CATY: 105593476(CRTC2)
PANU: 101017183(CRTC2)
TGE: 112636398(CRTC2)
RRO: 104663514(CRTC2)
RBB: 108518844(CRTC2)
TFN: 117065177(CRTC2)
PTEH: 111543705(CRTC2)
CJC: 103789006(CRTC2)
SBQ: 101040859(CRTC2)
CSYR: 103252138(CRTC2)
MMUR: 105885915(CRTC2)
OGA: 100955731(CRTC2)
MMU: 74343(Crtc2)
MCAL: 110291453(Crtc2)
MPAH: 110320038(Crtc2)
RNO: 310615(Crtc2)
MCOC: 116093209(Crtc2)
MUN: 110554243(Crtc2)
CGE: 100751848(Crtc2)
PLEU: 114707916(Crtc2)
NGI: 103751715(Crtc2)
HGL: 101709168(Crtc2)
CPOC: 100727423(Crtc2)
CCAN: 109688050(Crtc2)
DORD: 105984961(Crtc2)
DSP: 122109555(Crtc2)
NCAR: 124964238
OCU: 100358960(CRTC2)
OPI: 101522646(CRTC2)
TUP: 102481058(CRTC2)
CFA: 612305(CRTC2)
VVP: 112918870(CRTC2)
VLG: 121471329(CRTC2)
AML: 100472270(CRTC2)
UMR: 103668413(CRTC2)
UAH: 113245327(CRTC2)
UAR: 123783591(CRTC2)
ELK: 111138927
LLV: 125085649
MPUF: 101687620(CRTC2)
ORO: 101383200(CRTC2)
EJU: 114198645(CRTC2)
ZCA: 113933591(CRTC2)
MLX: 118013831(CRTC2)
FCA: 101101104(CRTC2)
PYU: 121015686(CRTC2)
PBG: 122475713(CRTC2)
PTG: 102953123(CRTC2)
PPAD: 109256187
HHV: 120221507(CRTC2)
BTA: 540959(CRTC2)
BOM: 102280934(CRTC2)
BIU: 109554474(CRTC2)
BBUB: 102397007(CRTC2)
CHX: 102180907(CRTC2)
OAS: 101102117(CRTC2)
ODA: 120855778(CRTC2) 120869894
CCAD: 122433317(CRTC2)
SSC: 100519835(CRTC2)
CFR: 102515899(CRTC2)
CBAI: 105068252(CRTC2)
CDK: 105089365(CRTC2)
VPC: 102536035(CRTC2)
BACU: 103004880(CRTC2)
LVE: 103086651(CRTC2)
OOR: 101287600(CRTC2)
DLE: 111167180(CRTC2)
PCAD: 112061832(CRTC2)
PSIU: 116757632(CRTC2)
ECB: 100056571(CRTC2)
EPZ: 103555397(CRTC2)
EAI: 106846251(CRTC2)
MYB: 102257000(CRTC2)
MYD: 102770919(CRTC2)
MMYO: 118672873(CRTC2)
MLF: 102417307(CRTC2)
MNA: 107543902(CRTC2)
PKL: 118721110(CRTC2)
HAI: 109373525(CRTC2)
DRO: 112316349(CRTC2)
SHON: 118990206(CRTC2)
AJM: 119061758(CRTC2)
PDIC: 114488806(CRTC2) 114490749
PHAS: 123804750(CRTC2)
MMF: 118637757(CRTC2)
RFQ: 117014506(CRTC2)
PALE: 102879203(CRTC2)
PGIG: 120592226(CRTC2)
PVP: 105296392(CRTC2)
RAY: 107509408(CRTC2)
MJV: 108408207(CRTC2)
TOD: 119236119(CRTC2)
SARA: 101548618(CRTC2)
LAV: 100673108(CRTC2)
TMU: 101344998
MDO: 100019951(CRTC2)
GAS: 123246108(CRTC2)
SHR: 100922824(CRTC2)
PCW: 110211993(CRTC2)
OAA: 114808055(CRTC2)
CJO: 107324475(CRTC2)
AFUL: 116499645(CRTC2)
TGU: 100221000(CRTC2)
LSR: 110476855(CRTC2)
SCAN: 108964479
PMOA: 120502618(CRTC2)
OTC: 121335667(CRTC2)
PRUF: 121353521(CRTC2)
FAB: 101816291(CRTC2)
PHI: 102110933(CRTC2)
PMAJ: 107214640(CRTC2)
FPG: 101923752(CRTC2)
FCH: 102050437(CRTC2)
CLV: 110364232(CRTC2)
EGZ: 104123012(CRTC2)
NNI: 104018282(CRTC2)
TALA: 116963238(CRTC2)
ACHC: 115345298(CRTC2)
AAM: 106484278(CRTC2)
AROW: 112973250(CRTC2)
DNE: 112984721
ASN: 102372662(CRTC2)
AMJ: 102571416(CRTC2)
CPOO: 109324723(CRTC2)
CMY: 102939459(CRTC2)
CPIC: 101942224(CRTC2)
TST: 117888792(CRTC2)
CABI: 116832723(CRTC2)
MRV: 120390318(CRTC2)
PVT: 110088491(CRTC2)
SUND: 121915926(CRTC2)
PBI: 103055527(CRTC2)
PMUR: 107285215(CRTC2)
TSR: 106552862
PGUT: 117657975(CRTC2)
VKO: 123032516(CRTC2)
PMUA: 114586231
ZVI: 118076023(CRTC2)
GJA: 107110880(CRTC2)
XTR: 101733698(crtc2)
RTEM: 120921026
BBUF: 120982461(CRTC2)
BGAR: 122923707(CRTC2)
DRE: 108179660
SRX: 107745155
CCAR: 109073074
IPU: 108256981(crtc2) 108267545
SMEO: 124384437
TFD: 113644502 113661567(crtc2)
TRU: 101063579(crtc2)
LCO: 109141940
ELY: 117265889
PLEP: 121945439
SLUC: 116064718
PFLV: 114556786
GAT: 120809993
PPUG: 119196992
MSAM: 119896920
CUD: 121513345
MZE: 101479703(crtc2)
ONL: 100694646(crtc2)
OAU: 116327806
OLA: 101166701
OML: 112136591
XMA: 102220988(crtc2)
XCO: 114141694(crtc2)
XHE: 116717872(crtc2)
PRET: 103477480(crtc2)
PFOR: 103155115
PLAI: 106958836(crtc2)
PMEI: 106907428(crtc2)
GAF: 122831719
CVG: 107095534(crtc2)
CTUL: 119780920
GMU: 124866047
NFU: 107378893
KMR: 108229424
NWH: 119409778
AOCE: 111568265
CSEM: 103388972(crtc2)
POV: 109646180
SSEN: 122775118
HHIP: 117776583
LCF: 108884694
SDU: 111234090
XGL: 120784772
HCQ: 109512134(crtc2)
BPEC: 110157907
MALB: 109970057
ELS: 105012688(crtc2) 105019155
SFM: 108941900
PKI: 111838365(crtc2) 111848277
LOC: 102693587
PSPA: 121309965
LCM: 102352254(CRTC2)
RTP: 109926463
PJA: 122247117
DFR: 124497675
 » show all
Reference
  Authors
Conkright MD, Canettieri G, Screaton R, Guzman E, Miraglia L, Hogenesch JB, Montminy M
  Title
TORCs: transducers of regulated CREB activity.
  Journal
Mol Cell 12:413-23 (2003)
DOI:10.1016/j.molcel.2003.08.013
Reference
  Authors
Iourgenko V, Zhang W, Mickanin C, Daly I, Jiang C, Hexham JM, Orth AP, Miraglia L, Meltzer J, Garza D, Chirn GW, McWhinnie E, Cohen D, Skelton J, Terry R, Yu Y, Bodian D, Buxton FP, Zhu J, Song C, Labow MA
  Title
Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells.
  Journal
Proc Natl Acad Sci U S A 100:12147-52 (2003)
DOI:10.1073/pnas.1932773100
  Sequence
[hsa:200186]

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