KEGG   ORTHOLOGY: K16507
Entry
K16507                      KO                                     

Name
DCHS1_2, PCDH16_23
Definition
protocadherin-16/23
Pathway
ko04391  Hippo signaling pathway - fly
ko04392  Hippo signaling pathway - multiple species
Disease
H01393  Van Maldergem syndrome
H01868  Mitral valve prolapse
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04391 Hippo signaling pathway - fly
    K16507  DCHS1_2, PCDH16_23; protocadherin-16/23
   04392 Hippo signaling pathway - multiple species
    K16507  DCHS1_2, PCDH16_23; protocadherin-16/23
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules
    K16507  DCHS1_2, PCDH16_23; protocadherin-16/23
Cell adhesion molecules [BR:ko04515]
 Cadherins
  Cadherin related
   K16507  DCHS1_2, PCDH16_23; protocadherin-16/23
Genes
HSA: 54798(DCHS2) 8642(DCHS1)
PTR: 451001(DCHS1) 471326(DCHS2)
PPS: 100987682(DCHS1) 100993387(DCHS2) 100993733
GGO: 101132281(DCHS2) 101148236(DCHS1)
PON: 100443552(DCHS1) 100459003(DCHS2)
NLE: 100601098(DCHS1) 100606055(DCHS2)
MCC: 697604(DCHS2) 711938(DCHS1)
MCF: 102115140(DCHS2) 102125003(DCHS1)
CSAB: 103236412 103241286(DCHS1)
RRO: 104677758(DCHS2) 104678306(DCHS1)
CJC: 100400245(DCHS2) 100412399(DCHS1)
MMU: 100534287(Dchs2) 233651(Dchs1)
MCAL: 110291856(Dchs2) 110299114(Dchs1)
MPAH: 110320813(Dchs2) 110326393(Dchs1)
RNO: 100909434 308912(Dchs1) 310550(Dchs2)
MUN: 110554319 110556077(Dchs2) 110559585(Dchs1)
CGE: 100760642(Dchs1) 100774272(Dchs2)
NGI: 103737569(Dchs1) 103751031(Dchs2)
HGL: 101702888(Dchs2) 101707793(Dchs1)
OCU: 100357034(DCHS1) 103350668(DCHS2) 103350669
TUP: 102475179(DCHS1) 102482414(DCHS2)
CFA: 111090102 476837(DCHS1) 482659(DCHS2)
AML: 100465636(DCHS2) 100473136(DCHS1)
UMR: 103658097(DCHS2) 103658098 103681434(DCHS1)
UAH: 113245857(DCHS1) 113255440(DCHS2)
ORO: 101364846(DCHS1) 101366836(DCHS2)
FCA: 101093545(DCHS1) 101100127(DCHS2) 111559083
PTG: 102955902(DCHS1) 102963100(DCHS2)
PPAD: 109262503(DCHS2) 109271079(DCHS1)
AJU: 106981146(DCHS1) 106982447(DCHS2)
BTA: 107133268 515576(DCHS1) 539323(DCHS2)
BOM: 102279507(DCHS1) 102285643(DCHS2)
BIU: 109569663(DCHS1)
BBUB: 102400161(DCHS2) 102405525(DCHS1)
CHX: 102169210(DCHS2) 102185761(DCHS1)
OAS: 101109908(DCHS1) 101122136(DCHS2) 114108867
SSC: 100623166(DCHS1) 100626442(DCHS2)
CFR: 102519647(DCHS1) 102523453(DCHS2)
CDK: 105089293(DCHS2) 105097905(DCHS1)
BACU: 103003507 103005250(DCHS2) 103010259(DCHS1)
LVE: 103069801 103084611(DCHS1)
OOR: 101276561(DCHS2) 101288504(DCHS1)
DLE: 111169161(DCHS1) 111187715(DCHS2)
PCAD: 102991213(DCHS2) 102994579(DCHS1)
ECB: 100055264(DCHS1) 100069855(DCHS2)
EAI: 106821795 106838176(DCHS1)
MYB: 102256893(DCHS1) 102259606(DCHS2)
MYD: 102771659(DCHS2) 102774307(DCHS1) 107184140
MNA: 107525607(DCHS2) 107540482(DCHS1)
HAI: 109376534(DCHS1) 109381999(DCHS2)
DRO: 112312187(DCHS2) 112312791(DCHS1)
PALE: 102880947(DCHS1) 102893222(DCHS2)
RAY: 107504346(DCHS1) 107506852 107510765(DCHS2)
LAV: 100663613(DCHS1) 100673313(DCHS2)
MDO: 100030982(DCHS1) 100620013(DCHS2)
SHR: 100918722(DCHS1) 100932466(DCHS2)
PCW: 110200516(DCHS1) 110213699(DCHS2)
OAA: 100081358(DCHS2) 114809114(DCHS1)
GGA: 419073(DCHS1) 769052(DCHS2)
MGP: 100545983(DCHS2) 100551201(DCHS1)
CJO: 107308569(DCHS1)
NMEL: 110391708(DCHS1) 110397489(DCHS2)
APLA: 101790765(DCHS1) 101795145(DCHS2)
ACYG: 106032268(DCHS2) 106049773(DCHS1)
LSR: 110470521(DCHS2) 110474962(DCHS1)
SCAN: 103824397(DCHS1) 103826227(DCHS2)
GFR: 102035484(DCHS1) 102036399(DCHS2)
FAB: 101808053(DCHS1) 101815109(DCHS2)
PHI: 102099865(DCHS2) 102105197(DCHS1)
PMAJ: 107202734(DCHS2) 107216119(DCHS1)
CCAE: 111928415(DCHS2) 111942757(DCHS1)
CCW: 104697315(DCHS2) 104698106(DCHS1)
ETL: 114066325(DCHS2) 114069905(DCHS1)
FPG: 101916067(DCHS2) 101920630(DCHS1)
FCH: 102051163(DCHS1) 102060025(DCHS2)
CLV: 102087567(DCHS2) 102098022
EGZ: 104126759(DCHS2) 104130617(DCHS1)
NNI: 104014882(DCHS1) 104021352(DCHS2)
ACUN: 113476009(DCHS1) 113479698(DCHS2)
PADL: 103921817(DCHS2) 103924870(DCHS1)
AAM: 106491874(DCHS2) 106497753(DCHS1)
ASN: 102377942(DCHS1) 102378025(DCHS2)
AMJ: 102560792(DCHS1) 102567137(DCHS2) 109282275
CMY: 102933283(DCHS1) 102944648(DCHS2)
CPIC: 101951611(DCHS2) 101953324(DCHS1)
PVT: 110072796(DCHS2) 110078119(DCHS1)
PBI: 103059863(DCHS1) 103065302(DCHS2)
PMUR: 107288660(DCHS1)
TSR: 106541885(DCHS1) 106543715 106553594(DCHS2)
PMUA: 114595133(DCHS1) 114603937(DCHS2)
XLA: 108704336 108704337(dchs2.S) 108707609(dchs1.L) 108710100(dchs1.S) 108719608(dchs2.L)
XTR: 100485624(dchs2) 100494036(dchs1)
NPR: 108788191(DCHS2) 108802034(DCHS1)
DRE: 100004458(dchs2) 100334632(dchs1a) 553300(dchs1b)
IPU: 108260639(dchs2) 108277286(DCHS1) 108278281
TRU: 101062627 105417686(dchs2)
BPEC: 110158557(dchs1) 110166096(dchs2) 110168350
LCM: 102356625 102364338(DCHS2)
CMK: 103173050 103188606(dchs1) 103189388(dchs2)
RTP: 109917723(dchs2) 109922374
APLC: 110980432
DME: Dmel_CG17941(ds)
DER: 6543282
DSE: 6617285
DSI: Dsimw501_GD22944(Dsim_GD22944)
DAN: 6497692
DSR: 110178127
DPE: 6595453
DMN: 108163037
DWI: 6644094
DAZ: 108611552
DNV: 108649476
DHE: 111599039
DVI: 6628308
AAG: 5565885
AME: 408767
BIM: 100749750
BTER: 100644155
OBB: 114877518
SOC: 105207553
MPHA: 105836051
AEC: 105146737
CFO: 105248839
PGC: 109856639
NVI: 100113866
CSOL: 105366109
MDL: 103571568
TCA: 662006(dachsous)
BMAN: 114243429
PRAP: 110999268
TNL: 113497560
API: 100167672
DNX: 107164118
RMD: 113549852
CLEC: 106665493
ZNE: 110827540
FCD: 110851066
TUT: 107367935
CSCU: 111626921
PTEP: 107449611
CEL: CELE_R10F2.1(cdh-1)
CBR: CBG15733(Cbr-cdh-1) CBG15736
LAK: 106160888
EGL: EGR_02139
NVE: 5512184
EPA: 110254828
DGT: 114529155
 » show all
Reference
  Authors
Nakajima D, Nakayama M, Kikuno R, Hirosawa M, Nagase T, Ohara O
  Title
Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs.
  Journal
Brain Res Mol Brain Res 94:85-95 (2001)
DOI:10.1016/S0169-328X(01)00218-2
  Sequence
[hsa:8642 54798]
Reference
  Authors
Thomas C, Strutt D
  Title
The roles of the cadherins Fat and Dachsous in planar polarity specification in Drosophila.
  Journal
Dev Dyn 241:27-39 (2012)
DOI:10.1002/dvdy.22736
Reference
  Authors
Hong JC, Ivanov NV, Hodor P, Xia M, Wei N, Blevins R, Gerhold D, Borodovsky M, Liu Y
  Title
Identification of new human cadherin genes using a combination of protein motif search and gene finding methods.
  Journal
J Mol Biol 337:307-17 (2004)
DOI:10.1016/j.jmb.2004.01.026
  Sequence
[hsa:54798]
Reference
  Authors
Cappello S, Gray MJ, Badouel C, Lange S, Einsiedler M, Srour M, Chitayat D, Hamdan FF, Jenkins ZA, Morgan T, Preitner N, Uster T, Thomas J, Shannon P, Morrison V, Di Donato N, Van Maldergem L, Neuhann T, Newbury-Ecob R, Swinkells M, Terhal P, Wilson LC, Zwijnenburg PJ, Sutherland-Smith AJ, Black MA, Markie D, Michaud JL, Simpson MA, Mansour S, McNeill H, Gotz M, Robertson SP
  Title
Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development.
  Journal
Nat Genet 45:1300-8 (2013)
DOI:10.1038/ng.2765
  Sequence
[mmu:233651]

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