KEGG ORTHOLOGY: K16744

ORTHOLOGY: K16744

Entry

K16744                      KO

Symbol

B9D1

Name

B9 domain-containing protein 1

Disease

H00261

Meckel syndrome

H00530

Joubert syndrome and related disorders

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K16744  B9D1; B9 domain-containing protein 1
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  MKS complex
   K16744  B9D1; B9 domain-containing protein 1

Other DBs

GO:

0036038

Genes

HSA:	27077(B9D1)

PTR:	742196(B9D1)

PPS:	100968638(B9D1)

GGO:	101139188(B9D1)

PON:	100450663(B9D1)

PPYG:

129017745(B9D1)

NLE:	100599563(B9D1)

HMH:	116483089(B9D1)

SSYN:

129462836(B9D1)

MCC:	702949(B9D1)

MCF:	102131705(B9D1)

MTHB:

126939055

MNI:	105493344(B9D1)

CSAB:

103242507(B9D1)

CATY:

105593714(B9D1)

PANU:

100999286(B9D1)

RRO:	104660709(B9D1)

RBB:	108516766(B9D1)

TFN:	117067582(B9D1)

PTEH:

111528151(B9D1)

CANG:

105520997(B9D1)

CJC:	100401864(B9D1)

SBQ:	101050010(B9D1)

CIMI:

108293481(B9D1)

ANAN:

105730696(B9D1)

CSYR:

103273100(B9D1)

MMUR:

105861949(B9D1)

LCAT:

123621111(B9D1)

PCOQ:

105823457(B9D1)

OGA:	100941259(B9D1)

MMU:	27078(B9d1)

MCAL:

110305302(B9d1)

MPAH:

110332057(B9d1)

RNO:	287383(B9d1)

MCOC:

116079246(B9d1)

ANU:	117709839(B9d1)

ASYL:

127695038(B9d1)

MUN:	110549806(B9d1)

CGE:	100774531(B9d1)

MAUA:

101835398(B9d1)

PROB:

127219166(B9d1)

PLEU:

114683281(B9d1)

MORG:

121456662(B9d1)

MFOT:

126514709

AAMP:

119812562(B9d1)

NGI:	103728220(B9d1)

HGL:	101726021(B9d1)

CPOC:

100728113(B9d1)

CCAN:

109699725(B9d1)

DORD:

105985877(B9d1)

DSP:	122103091(B9d1)

PLOP:

125366139(B9d1)

NCAR:

124980689

MMMA:

107157136(B9d1)

ITI:	101968805(B9d1)

OCU:

100340290

OPI:	101524769(B9D1)

TUP:	102475748(B9D1)

GVR:	103598191(B9D1)

CFA:	479519(B9D1)

CLUD:

112647274(B9D1)

VVP:	112924944(B9D1)

VLG:	121499671(B9D1)

NPO:	129497537(B9D1)

AML:	100470445(B9D1)

UMR:	103658545(B9D1)

UAH:	113271277(B9D1)

UAR:	123779780(B9D1)

ELK:

111139268

LLV:

125088029

MPUF:

101676295(B9D1)

MNP:	132003381(B9D1)

MLK:	131816873(B9D1)

NVS:	122906877(B9D1)

ORO:	101366390(B9D1)

EJU:	114198165(B9D1)

ZCA:	113908164(B9D1)

MLX:	118000128(B9D1)

NSU:	110584648(B9D1)

LWW:	102730226(B9D1)

FCA:	101097602(B9D1)

PYU:	121015739(B9D1)

PCOO:

112857100(B9D1)

PBG:	122485027(B9D1)

PVIV:

125151836(B9D1)

LRUF:

124519627

LGF:	123603098(B9D1)

AJU:

106981450

PTG:	102953976(B9D1)

PPAD:

109245792(B9D1)

PUC:

125926955

PLEZ:

122206870(B9D1)

HHV:	120228712(B9D1)

BTA:	505335(B9D1)

BOM:	102269955(B9D1)

BIU:	109573905(B9D1)

BBUB:

102403198(B9D1)

BBIS:

104990858(B9D1)

CHX:	102180795(B9D1)

OAS:	101110346(B9D1)

BTAX:

128065511(B9D1)

CSUM:

138083957(B9D1)

ODA:	120867404(B9D1)

CCAD:

122444188(B9D1)

MREE:

136148957(B9D1)

OVR:	110138521(B9D1)

MBEZ:

129544206(B9D1)

SSC:	110256122(B9D1)

CFR:	102507919(B9D1)

CBAI:

105083747(B9D1)

CDK:	105100561(B9D1)

VPC:	102541009(B9D1)

BACU:

103002984(B9D1)

BMUS:

118886432(B9D1)

LVE:	103080537(B9D1)

OOR:	101284564(B9D1)

LALB:

132510716(B9D1)

PCAD:

102981505(B9D1)

PSIU:

116746384(B9D1)

NASI:

112405056(B9D1)

ECB:	100063389(B9D1)

EPZ:	103565864(B9D1)

EAI:	106837915(B9D1)

MYB:	102258541(B9D1)

MYD:	102751601(B9D1)

MMYO:

118649410(B9D1)

MLF:	102439503(B9D1)

MDT:	132217949(B9D1)

MYUM:

138994353(B9D1)

PKL:	118726777(B9D1)

EFUS:

103299364(B9D1)

MNA:	107524521(B9D1)

DRO:	112308524(B9D1)

SHON:

119002743(B9D1)

AJM:	119062287(B9D1)

PDIC:

114515061(B9D1)

PHAS:

123809439(B9D1)

MMF:	118641258(B9D1)

PPAM:

129068689(B9D1)

RFQ:	117013947(B9D1)

PALE:

102897260(B9D1)

PGIG:

120589843(B9D1)

PVP:	105291384(B9D1)

RAY:	107511073(B9D1)

MJV:	108409114(B9D1)

TOD:	119231028(B9D1)

SARA:

101550250(B9D1)

SFUM:

130044063(B9D1)

SETR:

126013765(B9D1)

LAV:	100655871(B9D1)

TMU:

101346926

ETF:	101654476(B9D1)

DNM:	101422094(B9D1)

MDO:	100016238(B9D1)

GAS:	123235135(B9D1)

SHR:	100918009(B9D1)

AFZ:

127561393

PCW:	110220545(B9D1)

TVP:	118834178(B9D1)

PBRV:

138158889(B9D1)

OAA:	100084530(B9D1)

TACU:

119942296(B9D1)

GGA:	416525(B9D1)

PCOC:

116237601(B9D1)

MGP:	100546158(B9D1)

CJO:	107320660(B9D1)

TPAI:

128078894(B9D1)

LMUT:

125700538(B9D1)

NMEL:

110406136(B9D1)

APLA:

101803033(B9D1)

ACYG:

106032192(B9D1)

CATA:

118256425(B9D1)

AFUL:

116495227(B9D1)

TGU:	115497234(B9D1)

LSR:	110481788(B9D1)

SCAN:

103817831(B9D1)

PMOA:

120513304(B9D1)

OTC:	121334521(B9D1)

PRUF:

121350815(B9D1)

ATRC:

139597980(B9D1)

GFR:	102036656(B9D1)

FAB:	101816846(B9D1)

OMA:	130259434(B9D1)

PHI:	102108328(B9D1)

PMAJ:

107210940(B9D1)

CCAE:

111936157(B9D1)

CCW:	104685012(B9D1)

CBRC:

103615551

ACOE:

138118606(B9D1)

ETL:	114065990(B9D1)

ZAB:	102069553(B9D1)

ZLE:	135454064(B9D1)

ACHL:

103799046(B9D1)

SVG:	106864763(B9D1)

MMEA:

130582531(B9D1)

HRT:	120759629(B9D1)

SATI:

136367996(B9D1)

CCIC:

134050532(B9D1)

FPG:	101922112(B9D1)

FCH:

102046302

CCRI:

104155925

NNT:

104409977

SHAB:

115606680(B9D1)

ACUN:

113485792(B9D1)

TALA:

104357424(B9D1)

ACHC:

115335960(B9D1)

HALD:

104321451(B9D1)

HLE:	104833625(B9D1)

AGEN:

126034131

HHAR:

128134937(B9D1)

GCL:

127022538

CSTI:

104558060(B9D1)

LDI:	104353269(B9D1)

MNB:	103778304(B9D1)

DPUB:

104297474(B9D1)

PPUS:

135180784(B9D1)

AVIT:

104271618(B9D1)

BRHI:

104498458(B9D1)

EGZ:

104135732

NNI:	104015247(B9D1)

PCRI:

104030598(B9D1)

PCAO:

104053618(B9D1)

PADL:

103921450(B9D1)

AFOR:

103905023

FGA:

104078678

GSTE:

104259197(B9D1)

CLV:	102095263(B9D1)

MUI:	104533420(B9D1)

PGUU:

104467890(B9D1)

PLET:

104622815(B9D1)

EHS:	104507963(B9D1)

CMAC:

104479835(B9D1)

CUCA:

104060421(B9D1)

BREG:

104633796(B9D1)

ACAR:

104522791(B9D1)

CPEA:

104394042(B9D1)

CVF:	104289596(B9D1)

RTD:	128914275(B9D1)

CRID:

134520016(B9D1)

AAM:

106487443

AROW:

112974376(B9D1)

NPD:	112959939(B9D1)

TGT:	104567393(B9D1)

DNE:	112980415(B9D1)

SCAM:

104141201(B9D1)

ASN:	102369652 102385357

AMJ:	102558733(B9D1) 102569585(B9D1)

CPOO:

109314648(B9D1)

GGN:	109294372(B9D1)

PSS:

102443386

CMY:	102944961(B9D1)

CCAY:

125643827(B9D1)

DCC:	119862422(B9D1)

CPIC:

101945811(B9D1)

TST:	117884255(B9D1)

CABI:

116814819(B9D1)

MRV:	120374128(B9D1)

ACS:	103281096(b9d1)

ASAO:

132782102(B9D1)

PVT:	110070367(B9D1)

SUND:

121914830(B9D1)

PBI:	103058836(B9D1)

PMUR:

107289155(B9D1)

CTIG:

120319269(B9D1)

PGUT:

117679506(B9D1)

APRI:

131185376(B9D1)

PTEX:

113438858(B9D1)

NSS:	113422357(B9D1)

VKO:	123025246(B9D1)

PMUA:

114584717(B9D1)

PRAF:

128401600(B9D1)

ZVI:	118093196(B9D1)

HCG:	128336646(B9D1)

GJA:	107108873(B9D1)

STOW:

125430485(B9D1)

EMC:	129340729(B9D1)

XLA:	108702318 446392(b9d1.L)

XTR:	549063(b9d1)

NPR:	108793672(B9D1)

RTEM:

120943239(B9D1)

BBUF:

121008633(B9D1)

BGAR:

122945198(B9D1)

PWL:	138261301(B9D1)

MUO:	115476668(B9D1)

GSH:	117345715(B9D1)

DRE:	554150(b9d1)

SRX:	107720101 107737762 107756931

SANH:

107654544 107674617

SGH:	107581793(b9d1) 107592385

CCAR:

109108718 109109335

CAUA:

113050424 113078098

CGIB:

127951842 127952679

PTET:

122333114(b9d1)

LROH:

127160823(b9d1)

OMC:	131537452(b9d1)

PPRM:

120489940(b9d1)

RKG:	130095052(b9d1)

MAMB:

125269257(b9d1)

CIDE:

127508599

CERY:

137012488(b9d1)

MASI:

127450917

TROS:

130561258(b9d1)

TDW:	130425883(b9d1)

MANU:

129432961(b9d1)

PDAB:

135737651 135747755

IPU:	100528571(b9d1)

IFU:	128600386(b9d1)

PHYP:

113535963(b9d1)

SMEO:

124375899(b9d1)

TFD:	113643981(b9d1)

TVC:	132863917(b9d1)

CGAR:

128518742(b9d1)

NGRA:

132900743(b9d1)

TRN:	134307177(b9d1)

AMEX:

103038659(b9d1)

CMAO:

118805691(b9d1)

EEE:	113584940(b9d1)

CHAR:

105899922(b9d1)

SPIL:

134076343(b9d1)

TRU:	101062295(b9d1)

TFS:	130514729(b9d1)

TNG:	GSTEN00021851G001

LCO:	104925600(b9d1)

NCC:	104950528(b9d1)

TBEN:

117493037(b9d1)

CGOB:

115012007(b9d1)

PGEO:

117451387(b9d1)

GACU:

117552770(b9d1)

EMAC:

134878685(b9d1)

ELY:	117268459(b9d1)

EFO:	125879265(b9d1)

PLEP:

121957076(b9d1)

SLUC:

116065230(b9d1)

ECRA:

117957498(b9d1)

ESP:	116702461(b9d1)

PFLV:

114570356(b9d1)

GAT:	120827663(b9d1)

PPUG:

119220232(b9d1)

AFB:	129098924(b9d1)

CLUM:

117735262(b9d1)

PSWI:

130188321(b9d1)

CANA:

137786984(b9d1)

CVE:	137874290(b9d1)

MSAM:

119886033(b9d1)

CUD:	121529254(b9d1)

SPUL:

138604048(b9d1)

LMIX:

132954390(b9d1)

ALAT:

119014175(b9d1)

ASTR:

137609686(b9d1)

MZE:	101485298(b9d1)

ONL:	100706858(b9d1)

OAU:	116333260(b9d1)

OLA:	101164060(b9d1)

OML:	112146240(b9d1)

CSAI:

133422504(b9d1)

XMA:	102237715(b9d1)

XCO:	114159615(b9d1)

XHE:	116735095(b9d1)

PRET:

103469146(b9d1)

PFOR:

103151814(b9d1)

PLAI:

106951958(b9d1)

PMEI:

106914543(b9d1)

GAF:	122822299(b9d1)

PPRL:

129363344(b9d1)

CVG:	107088094(b9d1)

CTUL:

119793524(b9d1)

GMU:	124863191 124864492

NFU:	107376711(b9d1)

KMR:	108242982(b9d1)

ALIM:

106516532(b9d1)

NWH:	119422176(b9d1)

AOCE:

111565377(b9d1)

EJA:	138198359(b9d1)

BFRE:

138627580(b9d1)

MCEP:

124997609(b9d1)

CSEM:

103393185(b9d1)

POV:	109639507(b9d1)

SSEN:

122785085(b9d1)

SSOE:

131475073(b9d1)

HHIP:

117766773(b9d1)

HSP:	118123130(b9d1)

PPLT:

128458185(b9d1)

SMAU:

118288666(b9d1)

LCF:

108881066

SDU:	111230285(b9d1)

SLAL:

111647508(b9d1) 111662526

XGL:	120788035(b9d1)

HCQ:	109514906(b9d1)

SSCV:

125983544(b9d1)

SBIA:

133514244(b9d1)

PEE:	133414391(b9d1)

PTAO:

133465498(b9d1)

BPEC:

110160660(b9d1)

MALB:

109958841(b9d1)

BSPL:

114860845(b9d1)

SJO:	128378977(b9d1)

SSCO:

133999815(b9d1)

GMH:	115559851(b9d1)

SASA:

106597625(b9d1)

STRU:

115182374(b9d1)

OTW:	121843118(b9d1)

OMY:	110510645 118947124

OGO:	124021094(b9d1)

OKI:	116360844 116364151

OKE:	118383850(b9d1)

OMM:	135538751 135543968

OCLA:

139422369 139424108

SNH:	120040740(b9d1)

CCLU:

121540879(b9d1) 121562347 123490068

ELS:	105008323(b9d1)

SFM:	108941748(b9d1)

PKI:	111849186(b9d1)

AANG:

118220827(b9d1)

AROT:

135248232(b9d1)

CCOG:

133120404(b9d1)

LOC:	102692155(b9d1)

PSPA:

121331200(b9d1)

PSEX:

120542883(b9d1)

LCM:	102355380(B9D1)

CMK:	103187107(b9d1)

RTP:	109933974(b9d1)

CPLA:

122560528(b9d1)

HOC:	132825362(b9d1)

LERI:

129706983(b9d1)

PMRN:

116949552(B9D1)

LRJ:	133346570(B9D1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG14870(B9d1)

DER:

6553160

DSE:

6606244

DSI:	Dsimw501_GD19027(Dsim_GD19027)

DYA:	Dyak_GE24315

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI23223

DAZ:

108618319

DNV:

115562460

DHE:

111595223

DVI:	6631016(B9d1)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:	119670895 119670897 119672700

MDE:	101900407 131804378

SCAC:

106080755

LCQ:

111674983

LSQ:

119599866

CVJ:	135957478(B9d1)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ006605

CPII:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:	105673833(B9d1)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

DPA:

ESIM:

136416913(B9d1)

EFOR:

136347436(B9d1)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_215035

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137932436(B9d1)

PRAP:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

API:	100160805(B9d1)

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

106686904(B9d1)

NLU:

111053242

HVI:

124360078

MQU:

128992358

PHU:	Phum_PHUM253750

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_206137

DMK:

DPZ:

AFRA:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123764402(B9d1)

CQD:	128687932(B9d1)

PTRU:

123499794

ESN:

127004590

MNZ:

135197264

MRJ:	136841447(B9d1)

PORN:

139754799(B9d1)

EAF:

111701923

LSM:	121127130(B9d1)

TCF:

131883109

PPOI:

119113419 119113424 119113425 119113789 119113791

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

CVS:	136983871(B9d1)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_K03E6.4(mksr-1)

CBR:	CBG_11067(Cbr-mksr-1)

CRQ:	GCK72_022256

NAI:	NECAME_12547

BMY:	BM_BM4788(Bma-mksr-1)

LOA:	LOAG_10702

TSP:	Tsp_03052 Tsp_14689

HRO:	HELRODRAFT_88997

LGI:	LOTGIDRAFT_184197

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_011740

SHX:	MS3_00002517(B9D1_1)

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_52971

AQU:

100633761

CRE:	CHLRE_16g674627v5

VCN:	VOLCADRAFT_105683

MIS:	MICPUN_61278

MPP:	MICPUCDRAFT_27619

MBR:	MONBRDRAFT_24999

SRE:	PTSG_00476

BBES:

BESB_076760

TET:	TTHERM_00219110

PTM:	GSPATT00029931001 GSPATT00030141001

TPS:	THAPSDRAFT_264691

AAF:	AURANDRAFT_28991

PIF:	PITG_14588

SPAR:

SPRG_05772

TBR:	Tb10.61.2290

TBG:	TbgDal_X17560

TCR:	511283.294

LMA:	LMJF_32_0280

LIF:	LINJ_32_0290

LDO:	LDBPK_320290

LMI:	LMXM_31_0280

LMAT:

92511778(LSCM1_01666)

LOI:	92358647(LSCM4_02687)

LEIS:

94178472(GH5_02975)

LENR:

94169414(CUR178_02141)

LEIN:

94185903(JIQ42_02178)

PHET:

94288490(JKF63_02385)

NGR:	NAEGRDRAFT_52666

TVA:	TVAG_2v0080550 TVAG_2v0266890 TVAG_2v0494510 TVAG_2v0978690

SSAO:

94294145(SS50377_20122)

EHX:	EMIHUDRAFT_115658 EMIHUDRAFT_222627

GTT:	GUITHDRAFT_108112

» show all

Reference

PMID:19208769

Authors

Bialas NJ, Inglis PN, Li C, Robinson JF, Parker JD, Healey MP, Davis EE, Inglis CD, Toivonen T, Cottell DC, Blacque OE, Quarmby LM, Katsanis N, Leroux MR

Title

Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins.

Journal

J Cell Sci 122:611-24 (2009)
DOI:10.1242/jcs.028621

Sequence

[hsa:27077] [cel:CELE_K03E6.4]

Reference

PMID:21763481

Authors

Dowdle WE, Robinson JF, Kneist A, Sirerol-Piquer MS, Frints SG, Corbit KC, Zaghloul NA, van Lijnschoten G, Mulders L, Verver DE, Zerres K, Reed RR, Attie-Bitach T, Johnson CA, Garcia-Verdugo JM, Katsanis N, Bergmann C, Reiter JF

Title

Disruption of a ciliary B9 protein complex causes Meckel syndrome.

Journal

Am J Hum Genet 89:94-110 (2011)
DOI:10.1016/j.ajhg.2011.06.003

Sequence

[mmu:27078]

All links

Ontology (1)   
   GO (1)   
Gene (1385)   
   MGENES (123)   
   RefGene (1260)   
   OC (2)   
All databases (1386)   

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