KEGG   ORTHOLOGY: K16796Help
Entry
K16796                      KO                                     

Name
SOX2
Definition
transcription factor SOX2 (SOX group B)
Pathway
ko04390  Hippo signaling pathway
ko04550  Signaling pathways regulating pluripotency of stem cells
Disease
H00544  Septo-optic dysplasia
H02170  Microphthalmia, syndromic
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    K16796  SOX2; transcription factor SOX2 (SOX group B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K16796  SOX2; transcription factor SOX2 (SOX group B)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K16796  SOX2; transcription factor SOX2 (SOX group B)
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   HMG SOX
    K16796  SOX2; transcription factor SOX2 (SOX group B)
BRITE hierarchy
Genes
HSA: 6657(SOX2)
PTR: 460869(SOX2)
PPS: 100974432(SOX2)
GGO: 101130724(SOX2)
PON: 100460719(SOX2)
NLE: 100597138(SOX2)
MCC: 707039(SOX2)
MCF: 102140202(SOX2)
CSAB: 103221186(SOX2)
RRO: 104662510(SOX2)
CJC: 100407856(SOX2)
SBQ: 101037370(SOX2)
MMU: 20674(Sox2)
RNO: 499593(Sox2)
CGE: 100759815(Sox2) 103160737
NGI: 103735982(Sox2)
HGL: 101723266(Sox2)
CCAN: 109699101(Sox2)
OCU: 100341629(SOX2)
TUP: 102495142(SOX2)
CFA: 488092(SOX2)
AML: 100469604(SOX2)
UMR: 103676195(SOX2)
ORO: 101370199(SOX2)
FCA: 100379629(SOX2)
AJU: 113599867(SOX2)
BTA: 784383(SOX2)
BOM: 102282812(SOX2)
BIU: 109557709(SOX2)
PHD: 102340676(SOX2)
CHX: 100861576(SOX2)
OAS: 101110563(SOX2)
SSC: 407739(SOX2)
CFR: 102518283
CDK: 105086005(SOX2)
BACU: 103008627(SOX2)
LVE: 103076684
OOR: 101287070(SOX2)
ECB: 100146979(SOX2)
EPZ: 103552994(SOX2)
EAI: 106829295(SOX2)
MYB: 102252536(SOX2)
MYD: 102753513(SOX2)
HAI: 109371444(SOX2)
RSS: 109450256(SOX2)
PALE: 102887894(SOX2)
LAV: 100671571(SOX2)
TMU: 101356483
MDO: 100014523(SOX2)
SHR: 100918115(SOX2)
OAA: 100075503(SOX2)
GGA: 396105(SOX2)
MGP: 104915998(SOX2)
CJO: 107318220(SOX2)
APLA: 110353632(SOX2)
ACYG: 106032159(SOX2)
TGU: 100231711(SOX2)
SCAN: 103815317(SOX2)
GFR: 102034102(SOX2)
FAB: 101811073(SOX2)
PHI: 102111938(SOX2)
PMAJ: 107208924(SOX2)
CCAE: 111943875(SOX2)
CCW: 104688003(SOX2)
FPG: 101914046(SOX2)
FCH: 102052610(SOX2)
CLV: 102086348(SOX2)
EGZ: 104129988(SOX2)
NNI: 104019600(SOX2) 104021457
AAM: 106482257(SOX2)
ASN: 102384908(SOX2)
AMJ: 102575875(SOX2)
PSS: 102443720(SOX2)
CMY: 102941629(SOX2)
CPIC: 101941633(SOX2)
PVT: 110086067(SOX2)
PMUR: 107299233(SOX2)
GJA: 107106761(SOX2)
XLA: 398000(sox2.S)
XTR: 407873(sox2)
NPR: 108796023(SOX2)
DRE: 378723(sox2)
IPU: 108260177 108267652(sox19a) 108271395(sox2)
AMEX: 103042739(sox2)
TRU: 101073272(sox2) 101075119
LCO: 104923498(sox2) 109138101
NCC: 104941096(sox2)
MZE: 101485475(sox2)
OLA: 101162114(sox2) 110017107
XMA: 106699802(sox2)
PRET: 103463116(sox2)
NFU: 107392993(sox2)
KMR: 108248624(sox2)
CSEM: 103391903(sox15) 103399558(sox2)
LCF: 108890333(sox2)
SDU: 111227364(sox2)
HCQ: 109525320(sox2)
BPEC: 110160472(sox2) 110163893
MALB: 109969869(sox2)
LCM: 102355249 102366157(SOX2)
CMK: 103187986(sox2)
APLC: 110985307
AME: 408411
BIM: 100742000
BTER: 100643013
MPHA: 105829268
AEC: 105147001
ACEP: 105616998
CFO: 105249927
OBO: 105283718
MDL: 103569292
TCA: 663351(SoxN)
DPA: 109534699
NVL: 108558406
API: 100164548
DNX: 107164294
CLEC: 106665864
ZNE: 110841325
CEL: CELE_K08A8.2(sox-2)
CBR: CBG16696(Cbr-sox-2)
BMY: Bm1_27950
CRG: 105348069
OBI: 106876660
LAK: 106166716
ADF: 107329280
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Avilion AA, Nicolis SK, Pevny LH, Perez L, Vivian N, Lovell-Badge R
  Title
Multipotent cell lineages in early mouse development depend on SOX2 function.
  Journal
Genes Dev 17:126-40 (2003)
DOI:10.1101/gad.224503
Reference
  Authors
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S
  Title
Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
  Journal
Cell 131:861-72 (2007)
DOI:10.1016/j.cell.2007.11.019

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