KEGG   ORTHOLOGY: K16848Help
Entry
K16848                      KO                                     

Name
IQGAP1
Definition
Ras GTPase-activating-like protein IQGAP1
Pathway
ko04520  Adherens junction
ko04810  Regulation of actin cytoskeleton
ko05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
 09160 Human Diseases
  09161 Cancers: Overview
   05205 Proteoglycans in cancer
    K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
   04147 Exosome
    K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Others
     K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
  Exosomal proteins of breast milk
   K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
  Exosomal proteins of other body fluids (saliva and urine)
   K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
  Exosomal proteins of colorectal cancer cells
   K16848  IQGAP1; Ras GTPase-activating-like protein IQGAP1
BRITE hierarchy
Genes
HSA: 8826(IQGAP1)
PTR: 467762(IQGAP1)
PPS: 100985354(IQGAP1)
GGO: 101133145(IQGAP1)
PON: 100174194(IQGAP1)
NLE: 100596536(IQGAP1)
MCC: 709283(IQGAP1)
MCF: 101926449(IQGAP1)
CSAB: 103231193 103231194
RRO: 104679277(IQGAP1)
RBB: 108517209(IQGAP1)
CJC: 100398711(IQGAP1)
SBQ: 101030045(IQGAP1)
MMU: 29875(Iqgap1)
RNO: 361598(Iqgap1)
CGE: 100757264(Iqgap1)
NGI: 103749878(Iqgap1)
HGL: 101720196(Iqgap1)
CCAN: 109696764(Iqgap1)
OCU: 100344867(IQGAP1)
TUP: 102471568(IQGAP1)
CFA: 479050(IQGAP1)
AML: 100479587(IQGAP1)
UMR: 103660204(IQGAP1)
ORO: 101369803(IQGAP1)
FCA: 101087841(IQGAP1)
PTG: 102957368(IQGAP1)
AJU: 106965891(IQGAP1)
BTA: 104968536(IQGAP1)
BOM: 102281381(IQGAP1)
BIU: 109575386(IQGAP1)
PHD: 102327870(IQGAP1)
CHX: 102172668(IQGAP1)
OAS: 101104610(IQGAP1)
SSC: 100157656(IQGAP1)
CFR: 102513791(IQGAP1)
CDK: 105094701(IQGAP1)
BACU: 103019637(IQGAP1)
LVE: 103077891(IQGAP1)
OOR: 101273971(IQGAP1)
ECB: 100068724(IQGAP1)
EPZ: 103546217(IQGAP1)
EAI: 106832054
MYB: 102263858(IQGAP1)
MYD: 102766452(IQGAP1)
HAI: 109381492(IQGAP1)
RSS: 109437122(IQGAP1)
PALE: 102888464(IQGAP1)
LAV: 100660209(IQGAP1)
TMU: 101356521
MDO: 100014032(IQGAP1)
SHR: 100933251(IQGAP1)
OAA: 100078899(IQGAP1)
GGA: 415591(IQGAP3)
MGP: 100550295(IQGAP1)
CJO: 107318890(IQGAP1)
APLA: 101789617(IQGAP1)
ACYG: 106049780(IQGAP1)
TGU: 100220311
GFR: 102042572(IQGAP1)
FAB: 101809992(IQGAP1)
PHI: 102103186(IQGAP1)
PMAJ: 107209265(IQGAP1)
CCAE: 111933926(IQGAP1)
CCW: 104683841(IQGAP1)
FPG: 101912284(IQGAP1)
FCH: 102054787(IQGAP1)
CLV: 102089584(IQGAP1)
EGZ: 104125986(IQGAP1)
AAM: 106494098(IQGAP1)
ASN: 102381745(IQGAP1)
AMJ: 102569599(IQGAP1)
PSS: 102458593(IQGAP1)
CMY: 102935527(IQGAP1)
CPIC: 101949591(IQGAP1)
ACS: 100551905(iqgap1)
PVT: 110077222(IQGAP1)
PBI: 103059858(IQGAP1)
GJA: 107109718(IQGAP1)
XLA: 398589(iqgap1.L) 445857
XTR: 100127767(iqgap1)
NPR: 108795256(IQGAP1)
DRE: 100002928(iqgap1)
SGH: 107596412(iqgap1) 107600473
IPU: 108259258(iqgap1)
AMEX: 103043074
TRU: 101061053(iqgap1)
LCO: 104927249(iqgap1)
NCC: 104948912(iqgap1)
MZE: 101469891(iqgap1)
OLA: 101162510(iqgap1)
XMA: 102219414(iqgap1)
PRET: 103462973(iqgap1)
NFU: 107382018(iqgap1)
KMR: 108247124(iqgap1)
CSEM: 103398470(iqgap1)
LCF: 108894212(iqgap1)
SDU: 111222899(iqgap1)
HCQ: 109514308(iqgap1)
BPEC: 110168840(iqgap1)
MALB: 109954516(iqgap1)
SASA: 100380768(iqga1) 106562619
ELS: 105014938(iqgap1)
SFM: 108941147(iqgap1)
LCM: 102355177(IQGAP1)
CMK: 103188605(iqgap1)
SPU: 593982(IQGAP1)
APLC: 110987066
SKO: 100372429(IQGAP1)
AME: 100578255
BIM: 100750164
BTER: 100649365
SOC: 105202300
AEC: 105152807
ACEP: 105625088
PBAR: 105427787
HST: 105189343
DQU: 106746465
CFO: 105256966
LHU: 105667951
PGC: 109861546
PCF: 106788500
MDL: 103577741
BMOR: 101742168
PMAC: 106718621
PRAP: 110995830
HAW: 110375142
PXY: 105390828
API: 100168908(IQGAP2)
DNX: 107165459
CLEC: 106667199
CRG: 105346947
MYI: 110453997
OBI: 106872737
ADF: 107351294
HMG: 100200912(IQGAP)
AQU: 100634031
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Noritake J, Watanabe T, Sato K, Wang S, Kaibuchi K
  Title
IQGAP1: a key regulator of adhesion and migration.
  Journal
J Cell Sci 118:2085-92 (2005)
DOI:10.1242/jcs.02379
Reference
  Authors
Brown MD, Sacks DB
  Title
IQGAP1 in cellular signaling: bridging the GAP.
  Journal
Trends Cell Biol 16:242-9 (2006)
DOI:10.1016/j.tcb.2006.03.002
Reference
  Authors
Li Z, McNulty DE, Marler KJ, Lim L, Hall C, Annan RS, Sacks DB
  Title
IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner.
  Journal
J Biol Chem 280:13871-8 (2005)
DOI:10.1074/jbc.M413482200
  Sequence
[hsa:8826]

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