KEGG   ORTHOLOGY: K17065Help
Entry
K17065                      KO                                     

Name
DNM1L
Definition
dynamin 1-like protein [EC:3.6.5.5]
Pathway
ko04139  Mitophagy - yeast
ko04214  Apoptosis - fly
ko04217  Necroptosis
ko04621  NOD-like receptor signaling pathway
ko04668  TNF signaling pathway
Disease
H01900  Encephalopathy due to defective mitochondrial and peroxisomal fission
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    K17065  DNM1L; dynamin 1-like protein
 09140 Cellular Processes
  09141 Transport and catabolism
   04139 Mitophagy - yeast
    K17065  DNM1L; dynamin 1-like protein
  09143 Cell growth and death
   04214 Apoptosis - fly
    K17065  DNM1L; dynamin 1-like protein
   04217 Necroptosis
    K17065  DNM1L; dynamin 1-like protein
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K17065  DNM1L; dynamin 1-like protein
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K17065  DNM1L; dynamin 1-like protein
   03029 Mitochondrial biogenesis
    K17065  DNM1L; dynamin 1-like protein
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K17065  DNM1L; dynamin 1-like protein
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.5  Acting on GTP to facilitate cellular and subcellular movement
    3.6.5.5  dynamin GTPase
     K17065  DNM1L; dynamin 1-like protein
Membrane trafficking [BR:ko04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Dynamin
    K17065  DNM1L; dynamin 1-like protein
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    K17065  DNM1L; dynamin 1-like protein
   RhoA-dependent endocytosis
    K17065  DNM1L; dynamin 1-like protein
Mitochondrial biogenesis [BR:ko03029]
 Mitochondrial quality control factors
  Mitochondrial dynamics
   Fission and Fusion factors
    K17065  DNM1L; dynamin 1-like protein
   Retention of mitochondria
    K17065  DNM1L; dynamin 1-like protein
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K17065  DNM1L; dynamin 1-like protein
BRITE hierarchy
Other DBs
COG: COG0699
Genes
HSA: 10059(DNM1L)
PTR: 465266(DNM1L)
PPS: 100972805(DNM1L)
GGO: 101150167(DNM1L) 109025383
PON: 100458461(DNM1L)
NLE: 100583896(DNM1L)
MCC: 695388(DNM1L)
MCF: 101925205(DNM1L)
CSAB: 103218837(DNM1L)
RRO: 104668324(DNM1L)
RBB: 108538193(DNM1L)
CJC: 100390533(DNM1L)
SBQ: 101039686(DNM1L)
MMU: 74006(Dnm1l)
RNO: 114114(Dnm1l)
CGE: 100750819(Dnm1l)
NGI: 103731287(Dnm1l)
CCAN: 109689200 109689202(Dnm1l)
OCU: 100338814(DNM1L)
TUP: 102495046(DNM1L)
CFA: 477649(DNM1L)
AML: 100474116(DNM1L)
UMR: 103656150(DNM1L)
ORO: 101379539(DNM1L)
FCA: 101094189(DNM1L)
PTG: 102959135(DNM1L)
AJU: 106977409(DNM1L)
BTA: 540892(DNM1L)
BOM: 102268620(DNM1L)
BIU: 109558533 109559542(DNM1L)
PHD: 102338416(DNM1L)
CHX: 102180018(DNM1L)
OAS: 101108646(DNM1L)
SSC: 100624497(DNM1L)
CFR: 102516708(DNM1L)
CDK: 105084508(DNM1L)
BACU: 103015652(DNM1L)
LVE: 103083025(DNM1L)
OOR: 101270529(DNM1L)
ECB: 100070034(DNM1L)
EPZ: 103552054(DNM1L)
EAI: 106846957(DNM1L)
MYB: 102240524(DNM1L)
MYD: 102772882(DNM1L)
HAI: 109372452(DNM1L)
RSS: 109442814 109449878(DNM1L)
PALE: 102883219(DNM1L)
LAV: 100665946(DNM1L)
TMU: 101353980
MDO: 100012742(DNM1L) 100022725
GGA: 418132(DNM1L)
MGP: 100541339(DNM1L)
CJO: 107315715(DNM1L)
APLA: 101796617(DNM1L)
ACYG: 106030974(DNM1L)
TGU: 100229161(DNM1L)
GFR: 102041958(DNM1L)
FAB: 101821576(DNM1L)
PHI: 102101789(DNM1L)
PMAJ: 107204642(DNM1L)
CCW: 104696490(DNM1L)
FPG: 101921756(DNM1L)
FCH: 102056611(DNM1L)
CLV: 102084392(DNM1L)
EGZ: 104126186(DNM1L)
AAM: 106488599(DNM1L)
ASN: 102380635(DNM1L)
AMJ: 102568726(DNM1L)
PSS: 102457662(DNM1L)
CMY: 102933358(DNM1L) 102938375
ACS: 100560647(dnm1l) 100566729
PVT: 110078265(DNM1L) 110089196
PBI: 103052507 103058290(DNM1L)
GJA: 107111880(DNM1L) 107117362
XLA: 379244(MGC53884) 379875(dnm1l.L)
XTR: 100494576(dnm1l)
NPR: 108798761(DNM1L)
DRE: 393896(dnm1l) 566871(si:dkey-32e23.4)
IPU: 108265374 108269241(dnm1l)
AMEX: 103030788(dnm1l) 103036512
LCM: 102360171 102362872(DNM1L)
CMK: 103179403(dnm1l)
CIN: 100180573(dnm1l)
SPU: 577217(dnm1l)
APLC: 110988246
DME: Dmel_CG3210(Drp1)
DSI: Dsimw501_GD22819(Dsim_GD22819)
MDE: 101888875
AAG: 5571419
AME: 411472(Drp1)
BIM: 100741632
BTER: 100646574
SOC: 105199795
AEC: 105148002
ACEP: 105623467
PBAR: 105427871
HST: 105189859
CFO: 105251986
LHU: 105670264
PGC: 109852547
NVI: 100124244
TCA: 660635
DPA: 109543646
NVL: 108561038
BMOR: 101744411
PMAC: 106708523
PRAP: 110992552
PXY: 105391061
ZNE: 110831147
TUT: 107368101
CEL: CELE_T12E12.4(drp-1)
CBR: CBG19923(Cbr-drp-1)
BMY: Bm1_31610
TSP: Tsp_06787
CRG: 105328775
MYI: 110461247
OBI: 106867941
SHX: MS3_03326
HMG: 100215691
AQU: 100632064
ATH: AT2G14120(DRP3B) AT4G33650(DRP3A)
EGR: 104419877
LJA: Lj4g3v0386160.2(Lj4g3v0386160.2) Lj6g3v2192350.1(Lj6g3v2192350.1)
CSV: 101208055 101215383(Dynamin)
VVI: 100243718
INI: 109190517
DCR: 108227540
DOSA: Os01t0920400-01(Os01g0920400) Os04t0381000-01(Os04g0381000)
ATS: 109743753(LOC109743753) 109745633(LOC109745633) 109778656(LOC109778656)
ZMA: 100383931
CRE: CHLREDRAFT_195430(DRP3)
VCN: VOLCADRAFT_115648(drp3)
APRO: F751_5684
SCE: YKR001C(VPS1) YLL001W(DNM1)
KMX: KLMA_20110(DNM1) KLMA_30071(VPS1)
NCS: NCAS_0A01180(NCAS0A01180) NCAS_0A04970(NCAS0A04970)
NDI: NDAI_0C02270(NDAI0C02270) NDAI_0K02030(NDAI0K02030)
TPF: TPHA_0E02980(TPHA0E02980) TPHA_0G03350(TPHA0G03350)
TBL: TBLA_0B06480(TBLA0B06480) TBLA_0H02850(TBLA0H02850)
TDL: TDEL_0A02870(TDEL0A02870) TDEL_0E04110(TDEL0E04110)
KAF: KAFR_0D03460(KAFR0D03460) KAFR_0H03650(KAFR0H03650)
SLB: AWJ20_2055(DNM1) AWJ20_4293(VPS1) AWJ20_62(VPS1)
NTE: NEUTE1DRAFT56861(NEUTE1DRAFT_56861) NEUTE1DRAFT91539(NEUTE1DRAFT_91539)
BFU: BCIN_02g02630(Bcdnm1)
ANG: ANI_1_1470024(An02g10450) ANI_1_896034(An03g06950)
SPO: SPAC767.01c(vps1) SPBC12C2.08(dnm1)
ABP: AGABI1DRAFT111610(AGABI1DRAFT_111610) AGABI1DRAFT36087(AGABI1DRAFT_36087)
ABV: AGABI2DRAFT185821(AGABI2DRAFT_185821) AGABI2DRAFT190843(AGABI2DRAFT_190843)
DDI: DDB_G0277849(dymA) DDB_G0277851(dymB)
DFA: DFA_05937(dymA)
EHI: EHI_013180(282.t00012)
PYO: PY17X_0521500(PY04073)
PCB: PCHAS_052060(PC000555.02.0)
TAN: TA11580
TPV: TP02_0143
BBO: BBOV_III010040(17.m07872)
CPV: cgd2_3400
TGO: TGME49_267800(DRPA)
SMIN: v1.2.027040.t1(symbB.v1.2.027040.t1) v1.2.035111.t1(symbB.v1.2.035111.t1)
PTI: PHATRDRAFT_54751(DYN1)
TPS: THAPS_35266(DYN1)
SPAR: SPRG_05259
TCR: 508153.20
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Bleazard W, McCaffery JM, King EJ, Bale S, Mozdy A, Tieu Q, Nunnari J, Shaw JM
  Title
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast.
  Journal
Nat Cell Biol 1:298-304 (1999)
DOI:10.1038/13014
  Sequence
[sce:YLL001W]
Reference
PMID:9348079
  Authors
Shin HW, Shinotsuka C, Torii S, Murakami K, Nakayama K
  Title
Identification and subcellular localization of a novel mammalian dynamin-related protein homologous to yeast Vps1p and Dnm1p.
  Journal
J Biochem 122:525-30 (1997)
  Sequence
[hsa:10059]

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