KEGG   ORTHOLOGY: K17260
Entry
K17260                      KO                                     

Symbol
ACTR2, ARP2
Name
actin-related protein 2
Pathway
map04138  Autophagy - yeast
map04144  Endocytosis
map04530  Tight junction
map04666  Fc gamma R-mediated phagocytosis
map04810  Regulation of actin cytoskeleton
map05100  Bacterial invasion of epithelial cells
map05130  Pathogenic Escherichia coli infection
map05131  Shigellosis
map05132  Salmonella infection
map05135  Yersinia infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    K17260  ACTR2, ARP2; actin-related protein 2
   04138 Autophagy - yeast
    K17260  ACTR2, ARP2; actin-related protein 2
  09144 Cellular community - eukaryotes
   04530 Tight junction
    K17260  ACTR2, ARP2; actin-related protein 2
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    K17260  ACTR2, ARP2; actin-related protein 2
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    K17260  ACTR2, ARP2; actin-related protein 2
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    K17260  ACTR2, ARP2; actin-related protein 2
   05132 Salmonella infection
    K17260  ACTR2, ARP2; actin-related protein 2
   05131 Shigellosis
    K17260  ACTR2, ARP2; actin-related protein 2
   05135 Yersinia infection
    K17260  ACTR2, ARP2; actin-related protein 2
   05100 Bacterial invasion of epithelial cells
    K17260  ACTR2, ARP2; actin-related protein 2
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K17260  ACTR2, ARP2; actin-related protein 2
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins
    K17260  ACTR2, ARP2; actin-related protein 2
   04147 Exosome
    K17260  ACTR2, ARP2; actin-related protein 2
Membrane trafficking [BR:ko04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    K17260  ACTR2, ARP2; actin-related protein 2
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     K17260  ACTR2, ARP2; actin-related protein 2
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K17260  ACTR2, ARP2; actin-related protein 2
  Exosomal proteins of other body fluids (saliva and urine)
   K17260  ACTR2, ARP2; actin-related protein 2
  Exosomal proteins of bladder cancer cells
   K17260  ACTR2, ARP2; actin-related protein 2
Other DBs
COG: COG5277
Genes
HSA: 10097(ACTR2)
PTR: 746973(ACTR2)
PPS: 100984419(ACTR2)
GGO: 101135299 101146117(ACTR2)
PON: 100173969(ACTR2)
NLE: 100587384(ACTR2)
MCC: 697080(ACTR2)
MCF: 102117163(ACTR2)
CSAB: 103220149(ACTR2)
CATY: 105576480(ACTR2)
PANU: 101000314(ACTR2)
RRO: 104656189(ACTR2)
RBB: 108540803(ACTR2)
TFN: 117099748(ACTR2)
PTEH: 111550595(ACTR2)
CJC: 100392731(ACTR2)
SBQ: 101034581(ACTR2)
MMUR: 105871538(ACTR2)
MMU: 66713(Actr2)
MCAL: 110305500(Actr2)
MPAH: 110330537(Actr2)
RNO: 289820(Actr2)
MCOC: 116068010(Actr2)
MUN: 110540460(Actr2)
PLEU: 114703682(Actr2)
NGI: 103749563(Actr2)
HGL: 101711414(Actr2)
CCAN: 109685027(Actr2)
OCU: 100339213(ACTR2)
TUP: 102474683(ACTR2)
CFA: 481396(ACTR2)
VVP: 112934360(ACTR2)
VLG: 121491241(ACTR2)
AML: 100464823(ACTR2)
UMR: 103671799(ACTR2)
UAH: 113244810(ACTR2)
ORO: 101382123(ACTR2)
ELK: 111147990
MPUF: 101683212(ACTR2)
EJU: 114201274(ACTR2)
MLX: 118008048(ACTR2)
FCA: 101087729(ACTR2)
PYU: 121019097(ACTR2)
PTG: 102971744(ACTR2)
PPAD: 109260054(ACTR2)
AJU: 106976227(ACTR2)
HHV: 120239055(ACTR2)
BTA: 538486(ACTR2)
BOM: 102268534(ACTR2) 102276325
BIU: 109566217(ACTR2)
BBUB: 102402767(ACTR2)
CHX: 102174218(ACTR2)
OAS: 101112965(ACTR2)
ODA: 120851346(ACTR2)
CCAD: 122424660 122441845(ACTR2)
SSC: 100174962(ACTR2)
CFR: 102507886(ACTR2)
CBAI: 105075816(ACTR2)
CDK: 105088933(ACTR2)
BACU: 102999770(ACTR2)
LVE: 103072153(ACTR2)
OOR: 101284194(ACTR2)
DLE: 111186523(ACTR2)
PCAD: 102983608(ACTR2)
ECB: 100063005(ACTR2)
EPZ: 103560803(ACTR2)
EAI: 106828353(ACTR2)
MYB: 102252768(ACTR2)
MYD: 102753387(ACTR2)
MMYO: 118668933(ACTR2)
MNA: 107545978(ACTR2)
HAI: 109379151(ACTR2)
DRO: 112297870(ACTR2)
SHON: 118988448(ACTR2)
AJM: 119035060(ACTR2)
MMF: 118630616(ACTR2)
PALE: 102896516(ACTR2)
PGIG: 120621576(ACTR2)
RAY: 107518315(ACTR2)
MJV: 108392338(ACTR2)
TOD: 119259002(ACTR2)
LAV: 100668085(ACTR2)
MDO: 100033310(ACTR2)
SHR: 100928345(ACTR2)
PCW: 110207677(ACTR2)
OAA: 100082798(ACTR2)
GGA: 396147(ACTR2)
PCOC: 116232839(ACTR2)
MGP: 100538720(ACTR2)
CJO: 107310682(ACTR2)
NMEL: 110396013(ACTR2)
APLA: 101795715(ACTR2)
ACYG: 106044684(ACTR2)
TGU: 100231910(ACTR2)
LSR: 110484884(ACTR2)
SCAN: 103821396(ACTR2)
PMOA: 120506828(ACTR2)
GFR: 102033338(ACTR2)
FAB: 101807628(ACTR2)
PHI: 102110518(ACTR2)
PMAJ: 107201579(ACTR2)
CCAE: 111926525(ACTR2)
CCW: 104696588(ACTR2)
ETL: 114054872(ACTR2)
FPG: 101913819(ACTR2)
FCH: 102047800(ACTR2)
CLV: 102095333(ACTR2)
EGZ: 104126958(ACTR2)
NNI: 104018940(ACTR2)
ACUN: 113478064(ACTR2)
PADL: 103917830(ACTR2)
AAM: 106500105(ACTR2)
NPD: 112942908(ACTR2)
ASN: 102373979(ACTR2)
AMJ: 102574273(ACTR2)
CPOO: 109319538(ACTR2)
GGN: 109296936(ACTR2)
PSS: 102445782(ACTR2) 102461661
CMY: 102930625 102933572(ACTR2)
CPIC: 101949686 101954149(ACTR2)
TST: 117874276(ACTR2) 117880761
CABI: 116838795 116840133(ACTR2)
ACS: 100560302(actr2)
PVT: 110069801 110084211(ACTR2)
PBI: 103049979 103056628(ACTR2)
PMUR: 107287052(ACTR2)
TSR: 106547073(ACTR2)
PGUT: 117674448(ACTR2)
PMUA: 114586444 114593569(ACTR2)
ZVI: 118076034 118082570(ACTR2)
GJA: 107107618 107115229(ACTR2)
XLA: 443741(actr2.L) 734239(actr2.S)
XTR: 594957(actr2)
NPR: 108786547(ACTR2)
DRE: 406820(actr2a) 493612(zgc:101810) 554861(actr2b)
IPU: 108258541(actr2) 108263383 108267909(actr2a)
TRU: 101062388(actr2) 101079033
NCC: 104951274 104958382(actr2)
ELY: 117246130(zgc:101810) 117248156 117254603
PLEP: 121954521 121962339(zgc:101810)
SLUC: 116053379(zgc:101810) 116059209 116061799
ECRA: 117934625(zgc:101810) 117960070
GAT: 120814779 120821259(zgc:101810) 120825335(actr2a)
MSAM: 119913339(zgc:101810) 119915126(actr2a) 119917127
CUD: 121504264(zgc:101810) 121508103(actr2a) 121511535
MZE: 101465187(actr2) 101481337
ONL: 100695482 100710986(actr2)
OAU: 116314333(zgc:101810) 116324833
OLA: 101157161 101167566(actr2)
OML: 112156140(zgc:101810) 112161632
XMA: 102216726 102231009(actr2)
XCO: 114138158(actr2) 114157412
XHE: 116713843(actr2) 116732550
PRET: 103475930 103476483(actr2)
CTUL: 119773420(zgc:101810) 119798082
NFU: 107376067(actr2) 107377040
KMR: 108244593 108249093(zgc:101810)
AOCE: 111576835 111585653(actr2)
CSEM: 103386498 103387093(actr2)
POV: 109643804(actr2) 109646890
XGL: 120796664 120797169(zgc:101810) 120800830(actr2a)
HCQ: 109508375 109526693(actr2)
BPEC: 110156804(actr2) 110170710
MALB: 109961093(actr2) 109971420
SFM: 108927095 108933721(actr2)
LOC: 102687047(actr2)
LCM: 102351819(ACTR2) 102354173
CMK: 103181666(actr2)
RTP: 109922016(actr2)
BFO: 118427016
BBEL: 109483808
CIN: 100185499
SCLV: 120335647
SPU: 579126
APLC: 110975192
SKO: 100370835
DME: Dmel_CG9901(Arp2)
DER: 6550488
DSE: 6617952
DSI: Dsimw501_GD15743(Dsim_GD15743)
DAN: 6503489
DWI: 6649237
DGR: 6565534
DAZ: 108618285
DNV: 108657259
DHE: 111593080
DVI: 6632140
CCAT: 101460082
MDE: 101890958
LCQ: 111679104
ACOZ: 120957624
AARA: 120905798
AAG: 5575287
AALB: 109431598
CPII: 120429690
AME: 409313
ACER: 108002009
BBIF: 117212397
MGEN: 117221581
NMEA: 116433307
CGIG: 122399946
AEC: 105152814
ACEP: 105625097
VEM: 105566993
DQU: 106741095
CFO: 105259023
FEX: 115238137
LHU: 105679410
PGC: 109858945
OBO: 105278987
PCF: 106788959
NVI: 100114960
CSOL: 105361892
MDL: 103568920
CCIN: 107269144
TCA: 660637
DPA: 109543293
ATD: 109600559
AGB: 108905585
LDC: 111511211
NVL: 108566058
APLN: 108744708
PPYR: 116180945
OTU: 111422680
BMOR: 101740851
BMAN: 114241113
MSEX: 115450516
BANY: 112058088
PMAC: 106708092
PPOT: 106108896
PXU: 106125817
PRAP: 110999330
ZCE: 119836056
HAW: 110381479
TNL: 113505197
PXY: 105381864
API: 100166242
DNX: 107165153
AGS: 114127911
RMD: 113555754
BTAB: 109042618
DCI: 103511137
CLEC: 106665870
HHAL: 106686237
NLU: 111059630
ZNE: 110833492
CSEC: 111862901
FCD: 110845093
DMK: 116926212
PVM: 113812648
HAZT: 108669084
EAF: 111717938
DSV: 119458078
RSAN: 119374140
RMP: 119167393
VDE: 111243192
VJA: 111260041
TUT: 107368088
DPTE: 113792956
PTEP: 107446362
SDM: 118183684
CEL: CELE_K07C5.1(arx-2)
CBR: CBG09586(Cbr-arx-2)
BMY: BM_BM4867(Bma-arx-2)
TSP: Tsp_03079
PCAN: 112569796
BGT: 106069273
GAE: 121371250
CRG: 105340621
MYI: 110454919
PMAX: 117323796
OBI: 106878019
LAK: 106153816
EGL: EGR_00127
NVE: 5511840
EPA: 110240349
ATEN: 116289565
ADF: 107343631
AMIL: 114956639
PDAM: 113677468
SPIS: 111341503
DGT: 114532517
HMG: 100199620
AQU: 100638556
ATH: AT3G27000(ARP2)
ALY: 9311420
CRB: 17886466
THJ: 104825634
CPAP: 110825539
CIT: 102619658
PVY: 116129885
TCC: 18601060
GRA: 105769986
GAB: 108450277
EGR: 104414714
VRA: 106780120
VAR: 108329310
VUN: 114189455
CCAJ: 109818279
APRC: 113861505
CAM: 101496096
LJA: Lj1g3v3858560.1(Lj1g3v3858560.1) Lj1g3v3858560.2(Lj1g3v3858560.2)
ADU: 107494770
AIP: 107604996
FVE: 101294490
RCN: 112187865
PPER: 18783559
PMUM: 103330305
PAVI: 110764447
PDUL: 117621374
MNT: 21394092
CSV: 101213341
CMO: 103485464
BHJ: 120075790
MCHA: 111006424
RCU: 8285309
HBR: 110653538
MESC: 110612995
POP: 7456250
PEU: 105108363
PALZ: 118055289
JRE: 108987088
QLO: 115976404
TWL: 119992420
VVI: 100242912
VRI: 117930792
SLY: 101263559
SPEN: 107011945
SOT: 102583119
CANN: 107860787
NSY: 104233483
NTO: 104106238
NAU: 109218860
INI: 109178900
ITR: 116022758
SIND: 105177452
EGT: 105964071
HAN: 110904138
LSV: 111888887
CCAV: 112526618
DCR: 108204657
BVG: 104895232
SOE: 110789949
NNU: 104592820
MING: 122083980
NCOL: 116248012
OSA: 4345402
DOSA: Os08t0369300-00(Os08g0369300)
OBR: 102713760
BDI: 100846379
ATS: 109768925
SBI: 8077510
ZMA: 103633595
SITA: 101765541
PHAI: 112903263
PDA: 103698014
EGU: 105051023
MUS: 103973671
DCT: 110097873
PEQ: 110031007
AOF: 109830626
ATR: 18434473
SMO: SELMODRAFT_113120(ARP2-2) SELMODRAFT_175848(ARP2-1)
PPP: 112295614
VCN: VOLCADRAFT_107669(arp2)
APRO: F751_5002
OLU: OSTLU_29609(ARP3504)
SCE: YDL029W(ARP2)
ERC: Ecym_5237
KMX: KLMA_10173(ARP2)
NCS: NCAS_0C03550(NCAS0C03550)
NDI: NDAI_0G02900(NDAI0G02900)
TPF: TPHA_0A00920(TPHA0A00920)
TBL: TBLA_0F00870(TBLA0F00870)
TDL: TDEL_0D04610(TDEL0D04610)
KAF: KAFR_0C01040(KAFR0C01040)
PIC: PICST_36825(ARP2) PICST_64180(ARP10)
CAL: CAALFM_CR08950WA(ARP2)
SLB: AWJ20_4899(ARP2)
BNN: FOA43_004604(ARP2)
BBRX: BRETT_001808(ARP2)
NCR: NCU07171(arp2)
NTE: NEUTE1DRAFT143590(NEUTE1DRAFT_143590)
MGR: MGG_17001
SSCK: SPSK_09260
NHE: NECHADRAFT_71431(ARP2108)
MAW: MAC_02843
MAJ: MAA_08046
CMT: CCM_09669
BFU: BCIN_14g00120(Bcarp2)
MBE: MBM_06535
ANI: AN0673.2
ANG: ANI_1_900074(An08g06400)
ABE: ARB_03611
TVE: TRV_03224
PTE: PTT_09447
ZTR: MYCGRDRAFT_107178(ARP2401)
SPO: SPAC11H11.06(arp2)
CNE: CNI03340
CNB: CNBH3200
TASA: A1Q1_08113
ABP: AGABI1DRAFT114780(AGABI1DRAFT_114780)
ABV: AGABI2DRAFT194972(AGABI2DRAFT_194972)
MGL: MGL_1008
MRT: MRET_3147
DDI: DDB_G0272106(arpB)
DFA: DFA_04728(arpB)
EHI: EHI_111050(1.t00001)
CPV: cgd5_600
SMIN: v1.2.013956.t1(symbB.v1.2.013956.t1)
SPAR: SPRG_08841
 » show all
Reference
  Authors
Gournier H, Goley ED, Niederstrasser H, Trinh T, Welch MD
  Title
Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity.
  Journal
Mol Cell 8:1041-52 (2001)
DOI:10.1016/S1097-2765(01)00393-8
Reference
  Authors
Morrell JL, Morphew M, Gould KL
  Title
A mutant of Arp2p causes partial disassembly of the Arp2/3 complex and loss of cortical actin function in fission yeast.
  Journal
Mol Biol Cell 10:4201-15 (1999)
DOI:10.1091/mbc.10.12.4201
  Sequence
Reference
PMID:9230079
  Authors
Welch MD, DePace AH, Verma S, Iwamatsu A, Mitchison TJ
  Title
The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
  Journal
J Cell Biol 138:375-84 (1997)
DOI:10.1083/jcb.138.2.375
  Sequence
[hsa:10097]

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