KEGG ORTHOLOGY: K17360

ORTHOLOGY: K17360

Entry

K17360                      KO

Symbol

ACOT7

Name

acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]

Pathway

map00062

Fatty acid elongation

map01040

Biosynthesis of unsaturated fatty acids

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Reaction

R01274

palmitoyl-CoA hydrolase

R08174

stearoyl-CoA hydrolase

R08176

oleoyl-CoA hydrolase

R08177

linoleoyl-CoA hydrolase

R08178

R08181

R09450

long-chain fatty-acyl-CoA hydrolase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K17360  ACOT7; acyl-coenzyme A thioesterase 7
   01040 Biosynthesis of unsaturated fatty acids
    K17360  ACOT7; acyl-coenzyme A thioesterase 7
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins
    K17360  ACOT7; acyl-coenzyme A thioesterase 7
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K17360  ACOT7; acyl-coenzyme A thioesterase 7
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.2  palmitoyl-CoA hydrolase
     K17360  ACOT7; acyl-coenzyme A thioesterase 7
Lipid biosynthesis proteins [BR:ko01004]
Fatty acid synthase
  Component type
   K17360  ACOT7; acyl-coenzyme A thioesterase 7
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K17360  ACOT7; acyl-coenzyme A thioesterase 7

Other DBs

GO:

0052816

Genes

HSA:	11332(ACOT7)

PTR:	100609278 745616(ACOT7)

PPS:	100977829(ACOT7) 100978366

GGO:	101126562(ACOT7) 101140727

PON:	100173009(ACOT7)

PPYG:

129009105(ACOT7) 129035377

NLE:	100581694(ACOT7) 100591490

HMH:	116456657 116812845(ACOT7)

SSYN:

129472491(ACOT7)

MCC:	703288(ACOT7) 705407

MCF:	101866731(ACOT7) 102120236

MTHB:

126952575

MNI:	105479612(ACOT7) 105487726

CSAB:

103225695(ACOT7) 103246191

CATY:

105580943(ACOT7)

PANU:

101008252 101009689(ACOT7)

TGE:	112636333(ACOT7)

MLEU:

105540534(ACOT7) 105542154

RRO:	104657575(ACOT7) 104679127

RBB:	108517951(ACOT7)

TFN:	117093402(ACOT7)

PTEH:

111534758 111544611(ACOT7)

CANG:

105509161(ACOT7) 105516771

CJC:	100390157(ACOT7) 100409427

SBQ:	101032149(ACOT7)

CIMI:

108282372(ACOT7) 108315899

ANAN:

105731798(ACOT7)

CSYR:

103258638(ACOT7)

MMUR:

105886115

LCAT:

123634551(ACOT7)

ERUF:

138389117(ACOT7)

PCOQ:

105824975(ACOT7)

OGA:	100945377(ACOT7)

MMU:	70025(Acot7)

MCAL:

110292926(Acot7)

MPAH:

110322920(Acot7)

RNO:	26759(Acot7)

MCOC:

116097092(Acot7)

ANU:	117709257(Acot7)

ASYL:

127681723(Acot7)

MUN:	110552721(Acot7)

CGE:	100755154(Acot7)

MAUA:

101826987(Acot7)

PROB:

127213501(Acot7)

PLEU:

114702615(Acot7)

PMAV:

102904302(Acot7)

MORG:

121448036(Acot7)

MFOT:

126508177

AAMP:

119816492(Acot7)

CNL:	130883566(Acot7)

NGI:	103725124(Acot7)

HGL:	101705865(Acot7)

CPOC:

100725212(Acot7)

CCAN:

109688362(Acot7)

DORD:

106000306(Acot7)

DSP:	122102215(Acot7)

DMER:

138838118(Acot7)

PLOP:

125354511(Acot7)

NCAR:

124978275

MMMA:

107155554(Acot7) 107159506

ITI:	101970189(Acot7)

OCU:

100354701

OPI:	101517685(ACOT7)

OCZ:	121161452(ACOT7)

TUP:	102478970(ACOT7)

GVR:	103585899(ACOT7)

CFA:	479589(ACOT7)

CLUD:

112646927(ACOT7)

VVP:	112924697(ACOT7)

VLG:	121500761(ACOT7)

NPO:	129497472(ACOT7)

AML:	100469263(ACOT7)

UMR:	103666697(ACOT7)

UAH:	113270572(ACOT7)

UAR:	123796156(ACOT7)

ELK:

111154684

LLV:	125083067 125097443

MPUF:

101671178(ACOT7)

MNP:	132002288(ACOT7) 132013166

MLK:	131808899(ACOT7) 131826664

NVS:	122899383(ACOT7)

ORO:	101376949(ACOT7)

EJU:	114213162(ACOT7)

ZCA:	113909339(ACOT7)

MLX:	118020066(ACOT7)

NSU:	110574631(ACOT7)

LWW:

102741618

FCA:	101090371(ACOT7)

PYU:	121019917(ACOT7)

PCOO:

112868019(ACOT7)

PBG:	122479862(ACOT7)

PVIV:

125173551(ACOT7)

LRUF:

124516387

LGF:	123597106(ACOT7)

AJU:

106982203

PTG:	102956825(ACOT7)

PPAD:

109274019(ACOT7)

PUC:

125913170

PLEZ:

122226990(ACOT7)

HHV:	120244056 120245990(ACOT7)

BTA:	514788(ACOT7)

BOM:	102279443(ACOT7)

BIU:	109570593(ACOT7)

BBUB:

102391823(ACOT7)

BKE:	129653112(ACOT7)

BBIS:

104996068(ACOT7)

CHX:	102180523(ACOT7)

OAS:	101121789(ACOT7)

BTAX:

128061367(ACOT7)

CSUM:

138090622(ACOT7)

ODA:	120880143(ACOT7)

CCAD:

122452080(ACOT7)

MREE:

136169080(ACOT7)

OVR:	110144533(ACOT7)

MBEZ:

129551468(ACOT7)

SSC:	100514773(ACOT7)

CFR:	102517012(ACOT7)

CBAI:

105071017(ACOT7)

CDK:	105104722(ACOT7)

VPC:	102541330(ACOT7)

BACU:

102998002(ACOT7)

BMUS:

118900741(ACOT7)

LVE:	103076361(ACOT7)

OOR:	101269957(ACOT7)

LALB:

132515286(ACOT7)

GMF:	115865393(ACOT7)

DDP:	132435601(ACOT7)

DLE:	111187100(ACOT7)

PCAD:

102977545(ACOT7)

PSIU:

116756150(ACOT7)

PPHC:

136125749(ACOT7)

NASI:

112406999(ACOT7)

ECB:	100059575(ACOT7)

EPZ:	103558985(ACOT7)

EAI:	106844539(ACOT7)

MYB:	102260728(ACOT7)

MYD:	102752282(ACOT7)

MMYO:

118675910(ACOT7)

MLF:	102421351(ACOT7)

MDT:	132231744(ACOT7)

MYUM:

139001603(ACOT7)

PKL:	118705207 118731990(ACOT7)

EFUS:

103295292(ACOT7)

MNA:	107538453(ACOT7)

DRO:	112299443(ACOT7)

SHON:

118998139(ACOT7)

AJM:	119055949(ACOT7)

PDIC:

114496265(ACOT7)

PHAS:

123831685(ACOT7)

MMF:	118626629(ACOT7)

PPAM:

129078494(ACOT7)

HAI:	109392168(ACOT7)

RFQ:	117027445(ACOT7)

PALE:

102887428(ACOT7)

PGIG:

120585709(ACOT7)

PVP:	105297688(ACOT7)

RAY:	107521002(ACOT7)

MJV:	108406613(ACOT7)

TOD:	119235762(ACOT7)

SARA:

101545213(ACOT7)

SFUM:

130033329(ACOT7)

SETR:

126011536(ACOT7)

LAV:	100667124(ACOT7)

TMU:

101344810

ETF:	101652199(ACOT7)

DNM:	101417393(ACOT7)

MDO:	100026645(ACOT7)

GAS:	123240949(ACOT7) 123254827

SHR:	100918199(ACOT7)

AFZ:

127555938

PCW:	110199988(ACOT7)

TVP:	118837464(ACOT7)

PBRV:

138154583(ACOT7)

MLAO:

141509231(ACOT7)

OAA:	100084547(ACOT7)

TACU:

119928304(ACOT7)

GGA:	419371(ACOT7)

PCOC:

116242561(ACOT7)

MGP:	100547443(ACOT7)

CJO:	107323462(ACOT7)

TPAI:

128084939(ACOT7)

LMUT:

125703423(ACOT7)

NMEL:

110408754(ACOT7)

APLA:

101789631(ACOT7)

AACU:

137843440(ACOT7)

ACYG:

106047220(ACOT7)

CATA:

118253279(ACOT7)

AFUL:

116497671(ACOT7)

TGU:	100232141(ACOT7)

LSR:	110472517(ACOT7)

SCAN:

103820821(ACOT7)

PMOA:

120511057(ACOT7)

OTC:	121344084(ACOT7)

PRUF:

121358475(ACOT7)

ATRC:

139600643(ACOT7)

GFR:	102035195(ACOT7)

FAB:	101807279(ACOT7)

OMA:	130261817(ACOT7)

PHI:	102114502(ACOT7)

PMAJ:

107213584(ACOT7)

CCAE:

111938605(ACOT7)

CCW:	104693276(ACOT7)

CBRC:

103616145(ACOT7)

ACOE:

138121438(ACOT7)

ETL:	114060107(ACOT7)

ZAB:	102069647(ACOT7)

ZLE:	135456660(ACOT7)

ACHL:

103799648(ACOT7)

SVG:	106857684(ACOT7)

MMEA:

130579080(ACOT7)

HRT:	120762352(ACOT7)

SATI:

136370713(ACOT7)

CFAI:

136300583(ACOT7)

CCIC:

134052822(ACOT7)

FPG:	101917751(ACOT7)

FCH:	102046133(ACOT7)

CCRI:

104169531(ACOT7)

NNT:	104408015(ACOT7)

SHAB:

115617406(ACOT7)

ACUN:

113487926(ACOT7)

SURA:

141953951(ACOT7)

TALA:

104361258(ACOT7)

ACHC:

115342663(ACOT7)

HLE:	104830455(ACOT7)

AGEN:

126039955

HHAR:

128144176(ACOT7)

BBUT:

142030784(ACOT7)

GCL:

127024661

CSTI:

104562707(ACOT7)

MNB:	103775747(ACOT7)

DPUB:

104309894(ACOT7)

PPUS:

135190671(ACOT7)

AVIT:

104270985(ACOT7)

EGZ:	104132040(ACOT7)

NNI:	104008928(ACOT7)

PCRI:

104032839(ACOT7)

PARX:

142066663(ACOT7)

PADL:

103916262(ACOT7)

AFOR:

103894689(ACOT7)

FGA:	104073993(ACOT7)

CBOR:

142092314(ACOT7)

GSTE:

104261368(ACOT7)

CBOY:

140661671(ACOT7)

MAME:

142418647(ACOT7)

CLV:	102086257(ACOT7)

CNIC:

135997368(ACOT7)

MUI:	104545849(ACOT7)

PGUU:

104471978(ACOT7)

PLET:

104617575(ACOT7)

EHS:	104516796(ACOT7)

CMAC:

104480029(ACOT7)

CUCA:

104059868(ACOT7)

TEO:	104380826(ACOT7)

BREG:

104644016(ACOT7)

GAME:

129215969(ACOT7)

OHA:	104333814(ACOT7)

CPEA:

104395501(ACOT7)

CVF:	104290520(ACOT7)

RTD:	128918443(ACOT7)

CRID:

134524212(ACOT7)

LMIC:

141732078(ACOT7)

NARQ:

141473922(ACOT7)

AAM:	106492668(ACOT7)

AROW:

112975499(ACOT7)

NPD:	112957481(ACOT7)

TGT:	104570538(ACOT7)

DNE:	112995694(ACOT7)

SCAM:

104141971(ACOT7)

ASN:	102371135(ACOT7)

AMJ:	102558083(ACOT7)

CPOO:

109314184(ACOT7)

GGN:	109293592(ACOT7)

PSS:	102461234(ACOT7)

CIZ:	142000888(ACOT7)

CMY:	102930522(ACOT7)

CCAY:

125624359(ACOT7)

LKP:	140900062(ACOT7)

NDS:	142000716(ACOT7)

DCC:	119845026(ACOT7)

CPIC:

101937143(ACOT7)

TST:	117867834(ACOT7)

EOB:	135893489(ACOT7)

CABI:

116815425(ACOT7)

MRV:	120387821(ACOT7)

ACS:	100551908(acot7)

ASAO:

132764971(ACOT7)

PVT:	110082432(ACOT7)

SUND:

121937104(ACOT7)

PBI:	103057456(ACOT7)

PMUR:

107284665(ACOT7)

CTIG:

120318977(ACOT7)

TSR:	106549354(ACOT7)

PCAE:

139326199(ACOT7)

APRI:

131187165(ACOT7)

PTEX:

113449780(ACOT7)

NSS:	113423996(ACOT7)

VKO:	123017964(ACOT7)

PMUA:

114602351(ACOT7)

PRAF:

128419571(ACOT7)

ZVI:	118087070(ACOT7)

HCG:	128338600(ACOT7)

GJA:	107110578(ACOT7)

STOW:

125445942(ACOT7)

EMC:	129344670(ACOT7)

XLA:	108696607(acot7.L) 108697249

XTR:	779821(acot7)

NPR:	108804694(ACOT7)

RTEM:

120915897(ACOT7)

ACAT:

141111399(ACOT7)

PADS:

140341283(ACOT7)

BBUF:

120998804(ACOT7)

BGAR:

122928861(ACOT7)

DTC:	141074203(ACOT7)

PWL:	138300529(ACOT7)

MUO:	115456674(ACOT7)

GSH:	117349266(ACOT7)

DRE:	447878(acot7)

SRX:	107748973 107754737

SANH:

107687121 107693425

SGH:	107595775(acot7) 107602443

CCAR:

109079283 109090561

CAUA:

113039651 113107844

CGIB:

127963183 128018200

PTET:

122350041(acot7)

LROH:

127169211(acot7)

OMC:	131545587(acot7)

PPRM:

120473773(acot7)

RKG:	130082017(acot7)

MAMB:

125280321(acot7)

CIDE:

127517611

CERY:

137027299(acot7)

MASI:

127415186 127424749

TROS:

130549590(acot7)

TDW:	130440061(acot7)

MANU:

129414057(acot7)

PDAB:

135729925(acot7)

IPU:

108265054

IFU:	128607580(acot7)

PHYP:

113533403(acot7)

SMEO:

124400036(acot7)

TFD:	113656156(acot7)

TVC:	132854013(acot7)

CGAR:

128529686(acot7)

NGRA:

132892944(acot7)

TRN:	134317800(acot7)

AMEX:

103037715(acot7)

CMAO:

118813585(acot7)

EEE:	113578178(acot7)

CHAR:

105899067(acot7)

SPIL:

134087681(acot7)

ASAD:

121713063(acot7)

TRU:	101075291(acot7)

TFS:	130529701(acot7)

TNG:	GSTEN00022534G001

LCO:	104926410(acot7)

NCC:	104945179(acot7)

TBEN:

117494154(acot7)

CGOB:

115011378(acot7)

PGEO:

117450171(acot7)

GACU:

117541805(acot7)

EMAC:

134869875(acot7)

ELY:	117265632(acot7)

EFO:	125892163(acot7)

PLEP:

121947039(acot7)

SLUC:

116040723(acot7)

ECRA:

117947331(acot7)

ESP:	116692623(acot7)

PFLV:

114558725(acot7)

GAT:	120829582(acot7)

PPUG:

119221875(acot7)

AFB:	129100045(acot7)

CLUM:

117734155(acot7)

PSWI:

130199859(acot7)

CANA:

137801095(acot7)

CVE:	137889518(acot7)

MSAM:

119906222(acot7)

SCHU:

122882766(acot7)

EARM:

139288715(acot7)

CUD:	121517683(acot7)

SPUL:

138589669(acot7)

LMIX:

132989488(acot7)

HTC:	141799375(acot7)

ALAT:

119023283(acot7)

ASTR:

137589090(acot7)

PKLU:

139210249(acot7)

MZE:	101466734(acot7)

ONL:	100693869(acot7)

OAU:	116319009(acot7)

OLA:	101167535(acot7)

OML:	112158850(acot7)

CSAI:

133456521(acot7)

XMA:	102237860(acot7)

XCO:	114143995(acot7)

XHE:	116725419(acot7)

PRET:

103467275(acot7)

PFOR:

103138987(acot7)

PLAI:

106944882(acot7)

PMEI:

106915561(acot7)

GAF:	122832358(acot7)

PPRL:

129372477(acot7)

CVG:	107086633(acot7)

CTUL:

119795506(acot7)

GMU:	124871268(acot7)

NFU:	107390695(acot7)

KMR:	108236744(acot7)

ALIM:

106513033(acot7)

AOCE:

111568959(acot7)

EJA:	138193181(acot7)

BFRE:

138635767(acot7)

MCEP:

125000571(acot7)

CSEM:

103384470(acot7)

POV:	109630639(acot7)

SSEN:

122776596(acot7) 122785260

SSOE:

131469248(acot7)

HHIP:

117764841(acot7)

HSP:	118110356(acot7)

PPLT:

128442679(acot7)

SMAU:

118316548(acot7)

LCF:

108891665

SDU:	111219165(acot7)

SLAL:

111670592(acot7)

XGL:	120803407(acot7)

HCQ:	109514761(acot7)

SSCV:

125988390(acot7)

SBIA:

133508827(acot7)

PEE:	133405335(acot7)

PTAO:

133483007(acot7)

MALB:

109971641(acot7)

BSPL:

114858821(acot7)

SJO:	128356842(acot7)

SSCO:

133987810(acot7)

TTY:	137184286(acot7)

GMH:	115546552(acot7)

SASA:

106572204(acot7)

STRU:

115166104(acot7)

OTW:	112233041(acot7)

OMY:	110532161(acot7)

OGO:	124031835(acot7)

ONE:	115132045(acot7)

OKI:	109907895(acot7)

OKE:	118361244(acot7)

OMM:	135504515(acot7)

OCLA:

139417254

SALP:

111966348(acot7)

SNH:	120059409(acot7)

SFON:

129830238(acot7)

CCLU:

121538227(acot7)

ELS:	105013849(acot7)

OEP:	134019089(acot7)

SFM:	108924916(acot7)

PKI:	111859134(acot7)

AANG:

118208287(acot7)

AROT:

135233890(acot7)

CCOG:

133138922(acot7)

LOC:	102684375(acot7)

PSPA:

121328676 121328945

ARUT:

117425310 117963761

PSEX:

120531078(acot7)

LCM:	102366520(ACOT7)

CMK:	103184198(acot7)

RTP:	109918566(acot7)

CPLA:

122540397(acot7)

CPUN:

140486964(acot7)

HOC:	132833625(acot7)

SCAU:

119979742(acot7)

LERI:

129711754(acot7)

HAKA:

140718415(acot7)

PMRN:

116950453(ACOT7)

LRJ:	133352513(ACOT7)

BFO:

BBEL:

CIN:

SCLV:

CLEP:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:	100369260 100369403

PFLL:

139114694 139137807

HRO:	HELRODRAFT_85008

GAE:

LAK:

LLON:

NVE:

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HSY:

RES:

TAD:	TRIADDRAFT_26354 TRIADDRAFT_58304 TRIADDRAFT_58305 TRIADDRAFT_58306

AQU:

100635222

CCLM:

134195526

MBR:	MONBRDRAFT_1579

SRE:	PTSG_02905

» show all

Reference

PMID:23459938

Authors

Ellis JM, Wong GW, Wolfgang MJ

Title

Acyl coenzyme A thioesterase 7 regulates neuronal fatty acid metabolism to prevent neurotoxicity.

Journal

Mol Cell Biol 33:1869-82 (2013)
DOI:10.1128/MCB.01548-12

Sequence

[mmu:70025]

Reference

PMID:11834298

Authors

Kuramochi Y, Takagi-Sakuma M, Kitahara M, Emori R, Asaba Y, Sakaguchi R, Watanabe T, Kuroda J, Hiratsuka K, Nagae Y, Suga T, Yamada J

Title

Characterization of mouse homolog of brain acyl-CoA hydrolase: molecular cloning and neuronal localization.

Journal

Brain Res Mol Brain Res 98:81-92 (2002)
DOI:10.1016/S0169-328X(01)00323-0

Sequence

[mmu:70025]

All links

Ontology (1)   
   GO (1)   
Gene (455)   
   MGENES (210)   
   RefGene (243)   
   OC (2)   
All databases (456)   

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