KEGG   ORTHOLOGY: K17399Help
Entry
K17399                      KO                                     

Name
DNMT3B
Definition
DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
Pathway
ko00270  Cysteine and methionine metabolism
ko01100  Metabolic pathways
ko05206  MicroRNAs in cancer
Module
M00035  Methionine degradation
Disease
H00087  Other humoral immunodeficiencies
H02308  Immunodeficiency-centromeric instability-facial anomalies syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins
    K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B
   03036 Chromosome and associated proteins
    K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.37  DNA (cytosine-5-)-methyltransferase
     K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B
DNA replication proteins [BR:ko03032]
 Eukaryotic type
  DNA Replication Termination Factors
   DNA methylation enzymes
    K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic type
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B
BRITE hierarchy
Other DBs
RN: R04858
GO: 0003886
Genes
HSA: 1789(DNMT3B)
PTR: 458174(DNMT3B)
PPS: 100970194(DNMT3B)
GGO: 101154595(DNMT3B)
PON: 100459992(DNMT3B)
NLE: 100598378(DNMT3B)
MCC: 711553(DNMT3B)
MCF: 102129422(DNMT3B)
CSAB: 103248325(DNMT3B)
RRO: 104653701(DNMT3B)
RBB: 108537006(DNMT3B)
CJC: 100412936(DNMT3B)
SBQ: 101032211(DNMT3B)
MMU: 13436(Dnmt3b)
RNO: 444985(Dnmt3b)
MUN: 110550088(Dnmt3b)
HGL: 101725788(Dnmt3b)
CCAN: 109700875
OCU: 100349823(DNMT3B)
TUP: 102496734(DNMT3B)
CFA: 100685634(DNMT3B)
VVP: 112928250(DNMT3B)
AML: 100466728(DNMT3B)
UMR: 103674332(DNMT3B)
UAH: 113258482(DNMT3B)
ORO: 101386328(DNMT3B)
FCA: 101092926(DNMT3B)
PTG: 102956318(DNMT3B)
PPAD: 109272569(DNMT3B)
AJU: 106974616(DNMT3B)
BTA: 353354(DNMT3B)
BOM: 102272906(DNMT3B)
BIU: 109567360(DNMT3B)
BBUB: 102405870(DNMT3B)
CHX: 102186778(DNMT3B)
OAS: 106990108(DNMT3B)
SSC: 100302109(DNMT3B)
CFR: 102509075(DNMT3B)
CDK: 105090549(DNMT3B)
BACU: 103012471(DNMT3B)
LVE: 103074262(DNMT3B)
OOR: 101272017(DNMT3B)
DLE: 111184286(DNMT3B)
PCAD: 102981912(DNMT3B)
ECB: 100053900(DNMT3B)
EPZ: 103540207
EAI: 106833740(DNMT3B)
MYB: 102253340(DNMT3B)
MYD: 102758477(DNMT3B)
MNA: 107527791(DNMT3B)
HAI: 109384467(DNMT3B)
DRO: 112304113(DNMT3B)
PALE: 102891726(DNMT3B)
RAY: 107519503(DNMT3B)
MJV: 108390027(DNMT3B)
LAV: 100660290(DNMT3B)
TMU: 101340520
MDO: 100009884(DNMT3B)
SHR: 100935177(DNMT3B)
PCW: 110211476(DNMT3B)
OAA: 100089985(DNMT3B)
GGA: 419287(DNMT3B)
MGP: 100545756(DNMT3B)
CJO: 107323238(DNMT3B)
NMEL: 110408287(DNMT3B)
APLA: 101794583(DNMT3B)
ACYG: 106047128(DNMT3B)
TGU: 100218113(DNMT3B)
LSR: 110469002(DNMT3B)
SCAN: 103818660(DNMT3B)
GFR: 102039180(DNMT3B)
FAB: 101810075(DNMT3B)
PHI: 102100132(DNMT3B)
PMAJ: 107213458(DNMT3B)
CCAE: 111938145(DNMT3B)
CCW: 104687843(DNMT3B)
ETL: 114063052(DNMT3B)
FPG: 101911875(DNMT3B)
FCH: 102055043(DNMT3B)
CLV: 102092155(DNMT3B)
EGZ: 104127627(DNMT3B)
NNI: 104018311(DNMT3B)
ACUN: 113487681(DNMT3B)
PADL: 103912473(DNMT3B)
AAM: 106490852
ASN: 102377429(DNMT3B)
AMJ: 102574151(DNMT3B)
PSS: 102451768
CMY: 102931466(DNMT3B)
CPIC: 101945964(DNMT3B)
ACS: 100528060(dnmt3b)
PVT: 110086712(DNMT3B)
PBI: 103068010(DNMT3B)
PMUR: 107299513
TSR: 106551303
PMUA: 114599848(DNMT3B)
GJA: 107123019(DNMT3B)
DRE: 30659(dnmt3bb.2) 317744(dnmt3bb.1) 321084(dnmt3ba)
PRET: 103461915(dnmt3b) 103467741
LCM: 102367712(DNMT3B)
CMK: 103172120
RTP: 109914174
CIN: 100179842
BTAB: 109031790
DPX: DAPPUDRAFT_320126(DNMT3)
PTEP: 107457158
CRG: 105334030
OBI: 106869540
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Jurkowski TP, Jeltsch A
  Title
On the evolutionary origin of eukaryotic DNA methyltransferases and Dnmt2.
  Journal
PLoS One 6:e28104 (2011)
DOI:10.1371/journal.pone.0028104
Reference
  Authors
Ponger L, Li WH
  Title
Evolutionary diversification of DNA methyltransferases in eukaryotic genomes.
  Journal
Mol Biol Evol 22:1119-28 (2005)
DOI:10.1093/molbev/msi098
Reference
  Authors
Okano M, Bell DW, Haber DA, Li E
  Title
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
  Journal
Cell 99:247-57 (1999)
DOI:10.1016/S0092-8674(00)81656-6
  Sequence
[mmu:13436]

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