KEGG   ORTHOLOGY: K17505
Entry
K17505                      KO                                     
Symbol
PPM1K, PP2CM
Name
protein phosphatase 1K [EC:3.1.3.16]
Disease
H00172  Maple syrup urine disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K17505  PPM1K, PP2CM; protein phosphatase 1K
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     K17505  PPM1K, PP2CM; protein phosphatase 1K
Protein phosphatases and associated proteins [BR:ko01009]
 Protein serine/threonine phosphatases
  Mg2+- or Mn2+- dependent protein phosphatases (PPMs)
   PPM1 phosphatases (PP2C)
    K17505  PPM1K, PP2CM; protein phosphatase 1K
Other DBs
GO: 0004722
Genes
HSA: 152926(PPM1K)
PTR: 461368(PPM1K)
PPS: 100995592(PPM1K)
GGO: 101141730(PPM1K)
PON: 100174714(PPM1K)
NLE: 100583724(PPM1K)
MCC: 702398(PPM1K)
MCF: 102141701(PPM1K)
CSAB: 103235953(PPM1K)
CATY: 105576749(PPM1K)
PANU: 101018194(PPM1K)
TGE: 112625270(PPM1K)
RRO: 104664609(PPM1K)
RBB: 108544703(PPM1K)
TFN: 117085333(PPM1K)
PTEH: 111530859(PPM1K)
CJC: 100410897(PPM1K)
SBQ: 101028998(PPM1K)
MMUR: 105876375(PPM1K)
OGA: 100956906(PPM1K)
MMU: 243382(Ppm1k)
MCAL: 110296755(Ppm1k)
MPAH: 110316680(Ppm1k)
RNO: 312381(Ppm1k)
MCOC: 116098987(Ppm1k)
MUN: 110564240(Ppm1k)
CGE: 100763686(Ppm1k)
PLEU: 114710928(Ppm1k)
NGI: 103743378(Ppm1k)
HGL: 101723582(Ppm1k)
CPOC: 100723717(Ppm1k)
CCAN: 109700851(Ppm1k)
DORD: 105995913(Ppm1k)
DSP: 122097860(Ppm1k)
OCU: 100340852(PPM1K)
OPI: 101527987(PPM1K)
TUP: 102484960(PPM1K)
CFA: 478473(PPM1K)
VVP: 112919656(PPM1K)
VLG: 121492740(PPM1K)
AML: 100475039(PPM1K)
UMR: 103677888(PPM1K)
UAH: 113263160(PPM1K)
UAR: 123788343(PPM1K)
ELK: 111154614
MPUF: 101670139(PPM1K)
ORO: 101385323(PPM1K)
EJU: 114220141(PPM1K)
ZCA: 113924601(PPM1K)
MLX: 118010346(PPM1K)
FCA: 101093770(PPM1K)
PYU: 121032799(PPM1K)
PBG: 122478670(PPM1K)
PTG: 102951148(PPM1K)
PPAD: 109276116(PPM1K)
AJU: 106976215(PPM1K)
HHV: 120221186(PPM1K)
BTA: 540329(PPM1K)
BOM: 102273142(PPM1K)
BIU: 109560347(PPM1K)
BBUB: 102405526(PPM1K)
CHX: 102173647(PPM1K)
OAS: 101119821(PPM1K)
ODA: 120861954(PPM1K)
CCAD: 122422130(PPM1K)
SSC: 110262190(PPM1K)
CFR: 102523789(PPM1K)
CBAI: 105077703(PPM1K)
CDK: 105091569(PPM1K)
BACU: 103003216(PPM1K)
LVE: 103077336(PPM1K)
OOR: 101290439(PPM1K)
DLE: 111179055(PPM1K)
PCAD: 102976190(PPM1K)
PSIU: 116754098(PPM1K)
ECB: 100063504(PPM1K)
EPZ: 103553206(PPM1K)
EAI: 106831955(PPM1K)
MYB: 102242115(PPM1K)
MYD: 102760340(PPM1K)
MMYO: 118671319(PPM1K)
MLF: 102418723(PPM1K)
MNA: 107529727(PPM1K)
PKL: 118729070(PPM1K)
HAI: 109377044(PPM1K)
DRO: 112317807(PPM1K)
SHON: 118987062(PPM1K)
AJM: 119040112(PPM1K)
PDIC: 114493022(PPM1K)
PHAS: 123806854(PPM1K)
MMF: 118631494(PPM1K)
RFQ: 117022151(PPM1K)
PALE: 102891125(PPM1K)
PGIG: 120588308(PPM1K)
PVP: 105289567(PPM1K)
RAY: 107518927(PPM1K)
MJV: 108385385(PPM1K)
TOD: 119260478(PPM1K)
SARA: 101544979(PPM1K)
LAV: 100669396(PPM1K)
TMU: 101340270
DNM: 101447453(PPM1K)
MDO: 100024867(PPM1K)
GAS: 123251310(PPM1K)
SHR: 100917274(PPM1K)
PCW: 110209693(PPM1K)
OAA: 114812952(PPM1K)
GGA: 422614(PPM1K)
PCOC: 116231126(PPM1K)
MGP: 100546141
CJO: 107313458(PPM1K)
NMEL: 110397931(PPM1K)
APLA: 101793256(PPM1K)
ACYG: 106048171(PPM1K)
AFUL: 116489248(PPM1K)
TGU: 100227426(PPM1K)
LSR: 110476482(PPM1K)
SCAN: 103826082(PPM1K)
PMOA: 120497225(PPM1K)
OTC: 121339880(PPM1K)
PRUF: 121360196(PPM1K)
GFR: 102038274(PPM1K)
FAB: 101818110(PPM1K)
PHI: 102111088(PPM1K)
PMAJ: 107203364(PPM1K)
CCAE: 111928851(PPM1K)
CCW: 104697245(PPM1K)
ETL: 114057747(PPM1K)
ZAB: 102067362(PPM1K)
FPG: 101924666(PPM1K)
FCH: 102057478(PPM1K)
CLV: 102096560(PPM1K)
EGZ: 104127337(PPM1K)
NNI: 104021558(PPM1K)
ACUN: 113479629(PPM1K)
TALA: 104364700(PPM1K)
PADL: 103919901(PPM1K)
ACHC: 115345407(PPM1K)
AAM: 106494827(PPM1K)
AROW: 112970696(PPM1K)
NPD: 112951892(PPM1K)
DNE: 112985028(PPM1K)
ASN: 102385412(PPM1K)
AMJ: 106737213(PPM1K)
CPOO: 109322126(PPM1K)
GGN: 109303920(PPM1K)
PSS: 102462861(PPM1K)
CMY: 102935696(PPM1K)
CPIC: 101952046(PPM1K)
TST: 117878234(PPM1K)
CABI: 116836561(PPM1K)
MRV: 120406228(PPM1K)
ACS: 100562753(ppm1k)
PVT: 110080511(PPM1K)
SUND: 121931489(PPM1K)
PMUR: 107290996(PPM1K)
TSR: 106546819(PPM1K)
PGUT: 117678944(PPM1K)
VKO: 123022564(PPM1K)
PMUA: 114603977(PPM1K)
ZVI: 118083606(PPM1K)
GJA: 107110103(PPM1K)
XLA: 108711004(ppm1k.L) 432182(ppm1k.S)
XTR: 100487567(ppm1k)
NPR: 108784688(PPM1K)
RTEM: 120915334(PPM1K)
BBUF: 120989775(PPM1K)
BGAR: 122944721(PPM1K)
DRE: 503713(ppm1kb) 562087(si:ch211-149b19.3)
IPU: 108262962(ppm1kb)
PHYP: 113539821
SMEO: 124398704(ppm1ka) 124401816(ppm1kb)
AMEX: 103044547
EEE: 113591983
TRU: 101067181(ppm1k)
LCO: 104931319(ppm1k) 104932263
CGOB: 115011271(ppm1k) 115023549
ELY: 117245906 117255408(ppm1k)
PLEP: 121942089(ppm1kb) 121962108(ppm1ka)
SLUC: 116034241(ppm1k) 116061827
ECRA: 117935184(si:ch211-149b19.3) 117961185(ppm1k)
PFLV: 114545763 114569542(ppm1k)
GAT: 120821726(ppm1ka) 120824951(ppm1kb)
PPUG: 119218237(ppm1k) 119222986(si:ch211-149b19.3)
CUD: 121504702(ppm1ka) 121508360(ppm1kb)
MZE: 101464406 101478110(ppm1k)
ONL: 100700412 100701392(ppm1k)
OAU: 116319344 116330002(ppm1kb)
OML: 112137193(ppm1k) 112156484(si:ch211-149b19.3)
XMA: 102220408(ppm1k) 102229702
XCO: 114145634(ppm1k) 114156951
XHE: 116720206(ppm1k) 116733415
PRET: 103471014(ppm1k)
PFOR: 103144812(ppm1k) 103151629
PLAI: 106950625(ppm1k) 106962942
PMEI: 106928648(ppm1k) 106932816
GAF: 122821017(ppm1ka) 122829210(ppm1kb)
CVG: 107082778
CTUL: 119771658 119773883(ppm1k)
NFU: 107376848 107389354(ppm1k)
KMR: 108231009(ppm1k) 108251600
ALIM: 106517082(ppm1k) 106527320
NWH: 119410367 119423242(ppm1kb)
AOCE: 111582665(ppm1k) 111588619
CSEM: 103383314(ppm1k)
POV: 109638378(ppm1k) 109645856
SSEN: 122767204(ppm1ka) 122770621(ppm1kb)
HHIP: 117752138(si:ch211-149b19.3) 117767518(ppm1k)
LCF: 108873401(ppm1k) 108886841
SDU: 111233347 111240119(ppm1k)
SLAL: 111671192(ppm1k) 111673182
XGL: 120797274 120800702(ppm1kb)
HCQ: 109511173(ppm1k)
BPEC: 110153836(ppm1k)
MALB: 109951894 109955491(ppm1k)
OTW: 112261272(ppm1kb) 121847384
OGO: 124008440(ppm1ka) 124012146(ppm1kb)
ONE: 115123457(ppm1k)
SALP: 112074027(ppm1k)
ELS: 105020965(ppm1k) 105031515
SFM: 108924564(ppm1k)
PKI: 111837387
AANG: 118227877(ppm1k) 118231996
LOC: 102696178(ppm1k) 102696837
LCM: 102347504(PPM1K)
BFO: 118409440
BBEL: 109465381
SPU: 590885
DMK: 116932422
PCLA: 123746732
PTRU: 123506095
EAF: 111707981
DSV: 119436581
RSAN: 119399907
RMP: 119161515
DFR: 124496684
SDM: 118200931
BGT: 106078878
GAE: 121387766
HRF: 124149214
CRG: 105338899
PMAX: 117317793
MMER: 123557420
OSN: 115211791
NVE: 5518403
ATEN: 116306880
XEN: 124433353
HMG: 100208771
DOSA: Os11t0586001-00(Os11g0586001)
EHI: EHI_164420(54.t00015)
 » show all
Reference
  Authors
Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y
  Title
A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development.
  Journal
Genes Dev 21:784-96 (2007)
DOI:10.1101/gad.1499107
  Sequence
[hsa:152926] [mmu:243382]

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