Entry |
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Name |
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Definition |
cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
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Pathway |
ko00980 | Metabolism of xenobiotics by cytochrome P450 |
ko00982 | Drug metabolism - cytochrome P450 |
ko00983 | Drug metabolism - other enzymes |
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Disease |
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Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00830 Retinol metabolism
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6
09110 Biosynthesis of other secondary metabolites
00232 Caffeine metabolism
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6
00982 Drug metabolism - cytochrome P450
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6
00983 Drug metabolism - other enzymes
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6
09180 Brite Hierarchies
09181 Protein families: metabolism
00199 Cytochrome P450
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6
Enzymes [BR:ko01000]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
1.14.14.-
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6
Cytochrome P450 [BR:ko00199]
Cytochrome P450, animal type
CYP2 family
K17683 CYP2A6; cytochrome P450 family 2 subfamily A6
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Other DBs |
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Genes |
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Reference |
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Authors |
Miles JS, Bickmore W, Brook JD, McLaren AW, Meehan R, Wolf CR |
Title |
Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity. |
Journal |
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Sequence |
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Reference |
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Authors |
Fernandez-Salguero P, Hoffman SM, Cholerton S, Mohrenweiser H, Raunio H, Rautio A, Pelkonen O, Huang JD, Evans WE, Idle JR, et al. |
Title |
A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles. |
Journal |
Am J Hum Genet 57:651-60 (1995) |
Sequence |
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Reference |
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Authors |
Xu C, Goodz S, Sellers EM, Tyndale RF |
Title |
CYP2A6 genetic variation and potential consequences. |
Journal |
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